Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

The Insular Cortex And The Amygdala: Shared Functions And Interactions

R. Moraga-Amaro, Jimmy Stehberg
Published 2012 · Biology

Save to my Library
Download PDF
Analyze on Scholarcy
Share
The Insular Cortex (IC) is a portion of the cerebral cortex folded deep within the lateral sulcus – in rodents surrounding the rhinal fissure between the temporal and frontal lobes. The IC was first described by J.C. Reil in 1809 [1], after whom it received the name “the island of Reil”. Historically, the IC has been mentioned with several names, including “the central lobe”, “the fifth lobe”, “intersylvian convolutions” and “intralobular gyri” (reviewed in [2]).
This paper references
10.1016/j.brainres.2006.07.036
NMDA receptor antagonist MK-801 infused into the insular cortex prevents the attenuation of gustatory neophobia in rats
Yazmín Figueroa-Guzmán (2006)
Circulatory effects of cortical stimulation.
Delgado Jm (1960)
10.1016/j.brainres.2008.12.058
Conditioned taste aversion and latent inhibition following extensive taste preexposure in rats with insular cortex lesions
C. Roman (2009)
10.1002/CNE.902700105
Visceral cortex: Integration of the mucosal senses with limbic information in the rat agranular insular cortex
L. A. Krushel (1988)
10.1016/0006-8993(75)90469-2
The pontine taste area in the rat
R. Norgren (1975)
Circulatory effects of cortical stimulation.
J. M. Delgado (1960)
10.1016/0361-9230(82)90007-7
Special senses are really special: Evidence for a reciprocal, bilateral pathway between insular cortex and nucleus parabrachialis
M. Shipley (1982)
10.1016/j.nlm.2011.03.005
The role of the insular cortex in taste function
Jimmy Stehberg (2011)
Research note psychic ageusia in rats lacking gustatory neocortex.
J. Braun (1981)
10.1161/01.STR.30.5.946
Neglect after right insular cortex infarction.
F. Manes (1999)
10.1016/j.neuroimage.2006.10.032
Empathy for positive and negative emotions in the gustatory cortex
M. Jabbi (2007)
10.1016/j.pain.2009.07.014
Somatotopic organization of pain responses to direct electrical stimulation of the human insular cortex
L. Mazzola (2009)
10.1523/JNEUROSCI.19-17-07661.1999
Redundant Basal Forebrain Modulation in Taste Aversion Memory Formation
H. Gutiérrez (1999)
10.1016/0166-4328(94)90107-4
Tetrodotoxin blockade of amygdala overlapping with poisoning impairs acquisition of conditioned taste aversion in rats
G. Roldán (1994)
10.1016/0006-8993(71)90521-X
Unit study of exteroceptive inputs to claustrocortex in awake, sitting, squirrel monkey.
K. Sudakov (1971)
Cerebrogenic cardiac arrhythmias : Cortical lateralization and clinical significance
S. Oppenheimer (2014)
10.1093/cercor/bhn054
Auditory, somatosensory, and multisensory insular cortex in the rat.
K. M. Rodgers (2008)
10.1146/ANNUREV.NEURO.27.070203.144157
The amygdala modulates the consolidation of memories of emotionally arousing experiences.
J. D. McGaugh (2004)
10.1016/S0031-9384(01)00433-4
Effects of amygdala lesions on body weight, conditioned taste aversion, and neophobia
B. L. Rollins (2001)
10.1186/1744-9081-8-8
Generalized anxiety modulates frontal and limbic activation in major depression
M. Schlund (2011)
10.1016/S0006-8993(00)02397-0
Different disruptive effects on the acquisition and expression of conditioned taste aversion by blockades of amygdalar ionotropic and metabotropic glutamatergic receptor subtypes in rats
Y. Yasoshima (2000)
10.1037//0033-295x.101.2.222
William James and emotion: is a century of fame worth a century of misunderstanding?
P. Ellsworth (1994)
10.1002/CNE.903080210
Efferent projections of the infralimbic cortex of the rat
K. Hurley (1991)
The Insular Cortex and the Amygdala: Shared Functions and Interactions 255
Autonomic and myocardial changes in middle cerebral artery stroke models in the rat
D Cechetto (1989)
10.1523/JNEUROSCI.1246-08.2008
Contextual Fear Conditioning in Humans: Cortical-Hippocampal and Amygdala Contributions
Ruben P. Alvarez (2008)
10.1016/S0306-4522(01)00316-5
The visceral sector of the thalamic reticular nucleus in the rat
J. Stehberg (2001)
10.1002/hbm.21416
Localization of pain‐related brain activation: A meta‐analysis of neuroimaging data
E. G. Duerden (2013)
10.1016/0304-3940(81)90235-4
Access to the cerebral cortex of extra-lingual taste inputs in the rat
T. Yamamoto (1981)
10.1016/0006-8993(89)90625-2
Autonomic and myocardial changes in middle cerebral artery occlusion: stroke models in the rat
D. Cechetto (1989)
10.1152/AJPREGU.1984.246.5.R832
Units in the amygdala responding to activation of carotid baro- and chemoreceptors.
D. Cechetto (1984)
10.1006/nlme.2002.4082
Amygdala Modulation of Memory Consolidation: Interaction with Other Brain Systems
J. D. McGaugh (2002)
10.1016/j.neuroimage.2007.04.043
A structural neural deficit in adolescents with conduct disorder and its association with lack of empathy
P. Sterzer (2007)
Functional imaging of brain responses to pain. A review, meta-analysis
R Peyron (2000)
10.1176/FOC.7.2.FOC274
Emotion circuits in the brain.
Joseph E LeDoux (2000)
10.1016/0166-4328(95)00262-6
Transient impairment of cholinergic function in the rat insular cortex disrupts the encoding of taste in conditioned taste aversion
Cathy Naor (1996)
10.1111/J.1748-1716.1958.TB01565.X
The effect of stimulation of autonomic areas in the cerebral cortex upon the adrenaline and noradrenaline secretion from the adrenal gland in the cat.
U. V. Von Euler (1958)
10.1152/JN.1953.16.5.499
Cortical organization in gustation (Macaca mulatta).
M. Bagshaw (1953)
10.1007/s00429-010-0263-z
Anterior insula degeneration in frontotemporal dementia
W. Seeley (2010)
10.1016/0168-0102(90)90004-X
Taste area in granular and dysgranular insular cortices in the rat identified by stimulation of the entire oral cavity
H. Ogawa (1990)
10.1002/hbm.21131
Within‐limb somatotopic representation of acute muscle pain in the human contralateral dorsal posterior insula
L. Henderson (2011)
10.1016/0168-0102(94)90165-1
Anatomical location of a taste-related region in the thalamic reticular nucleus in rats
T. Hayama (1994)
10.1016/s0140-6736(00)47063-7
The Cerebral Cortex of Man
W. Penfield (1950)
10.1002/CNE.902700310
Neurons containing calcitonin gene‐related peptide in the parabrachial nucleus project to the central nucleus of the amygdala
J. Schwaber (1988)
10.1016/0006-8993(86)90787-0
Gustatory cortex in the rat. I. Physiological properties and cytoarchitecture
E. Kosar (1986)
10.1016/0006-8993(84)90899-0
Projections from the parvocellular part of the posteromedial ventral nucleus of the thalamus to the lateral amygdaloid nucleus in the cat
Y. Yasui (1984)
10.1002/CNE.902050104
Connections of the amygdala of the rat. IV: Corticoamygdaloid and intraamygdaloid connections as studied with axonal transport of horseradish peroxidase
O. Ottersen (1982)
10.1016/j.biopsycho.2011.10.010
Insula reactivity and connectivity to anterior cingulate cortex when processing threat in generalized social anxiety disorder
H. Klumpp (2012)
10.1016/j.neuroimage.2003.11.003
The neural correlates of maternal and romantic love
A. Bartels (2004)
10.1002/(SICI)1096-9861(19990322)405:4<421::AID-CNE1>3.0.CO;2-2
Differential projections to the intralaminar and gustatory thalamus from the parabrachial area: A PHA‐L study in the rat
H. Bester (1999)
10.1002/cne.20749
Neural mechanisms of autonomic, affective, and cognitive integration
H. Critchley (2005)
10.1001/archopht.1951.01700010242018
The Cerebral Cortex of Man: A Clinical Study of Localization of Function
W. Penfield (1950)
Conditioned Taste Aversion-Memory of a Special Kind : Oxford Psychology Series, Jan Bures, Federico Bermudez-Rattoni, 山本隆著, 192頁, 18,150円, Oxford University Press, 1998年, ISBN 019 8523475
松尾 龍二 (1999)
10.1152/JN.1990.63.4.689
Gustatory responses of single neurons in the insula of the macaque monkey.
S. Yaxley (1990)
10.1002/CNE.903230204
The organization of the thalamocortical connections of the mediodorsal thalamic nucleus in the rat, related to the ventral forebrain–prefrontal cortex topography
J. P. Ray (1992)
10.1136/BMJ.310.6988.1213
Descartes' Error: Emotion, Reason and the Human Brain
S. Spence (1995)
10.1016/S0166-4328(05)80328-6
Differential involvement of gustatory insular cortex and amygdala in the acquisition and retrieval of conditioned taste aversion in rats
M. Gallo (1992)
Neocortico-amygdalar interaction in the conditioned taste aversion in rats.
O. Burešová (1978)
10.1016/j.schres.2010.08.027
The role of the insula in schizophrenia
Korey P. Wylie (2010)
10.1111/j.0953-816X.2004.03215.x
Amygdalar circuits required for either consolidation or extinction of taste aversion memory are not required for reconsolidation
A. Bahar (2004)
10.1136/jnnp.20.1.11
LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS
W. Scoville (1957)
10.1037//0735-7044.112.5.1104
The parabrachial nucleus is essential for acquisition of a conditioned odor aversion in rats.
P. S. Grigson (1998)
10.1037/H0033815
Effect of US habituation following conditioning.
R. Rescorla (1973)
10.1037//0735-7044.106.1.140
Taste avoidance, but not aversion, learning in rats lacking gustatory cortex.
S. Kiefer (1992)
10.1002/CNE.902770303
Efferent connections of the substantia innominata in the rat
E. Grove (1988)
10.1080/01616412.1985.11739692
The insular lobe in primates including humans.
J. Augustine (1985)
10.1016/j.brainresbull.2003.08.009
Effects of excitotoxic lesions of the gustatory thalamus on latent inhibition and blocking of conditioned taste aversion in rats
S. Reilly (2003)
10.1037//0735-7044.112.1.172
Long-term memory retrieval deficits of learned taste aversions are ameliorated by cortical fetal brain implants.
C. Ormsby (1998)
10.1016/S0925-4927(97)00063-2
Functional MRI reveals left amygdala activation during emotion
Frank Schneider (1997)
Latent inhibition: a review and a new hypothesis.
K. R. Weiss (1974)
10.1016/j.biopsych.2008.09.028
Binge-Eating Disorder: Reward Sensitivity and Brain Activation to Images of Food
A. Schienle (2009)
Somato-motor, autonomic and electrocorticographic responses to electrical stimulation of rhinencephalic and other structures in primates, cat, and dog; a study of responses from the limbic, subcallosal, orbito-insular, piriform and temporal cortex, hippocampus-fornix and amygdala.
B. Kaada (1951)
10.1016/0006-8993(80)91117-8
Efferent connections of the parabrachial nucleus in the rat
C. Saper (1980)
10.1016/j.autneu.2006.01.006
Visceral-related area in the rat insular cortex
V. Bagaev (2006)
10.1016/S0006-8993(99)01519-X
Differential effects of 192IgG-saporin and NMDA-induced lesions into the basal forebrain on cholinergic activity and taste aversion memory formation
H. Gutiérrez (1999)
10.1016/0168-0102(95)00875-T
Conditioned taste aversion in rats with excitotoxic brain lesions
Takashi Yamamoto (1995)
10.1073/PNAS.96.20.11642
Basolateral amygdala noradrenergic influence enables enhancement of memory consolidation induced by hippocampal glucocorticoid receptor activation.
B. Roozendaal (1999)
10.1126/SCIENCE.1058165
Memory Extinction, Learning Anew, and Learning the New: Dissociations in the Molecular Machinery of Learning in Cortex
Diego E. Berman (2001)
10.1037/0735-7044.113.6.1242
Gustatory thalamus lesions eliminate successive negative contrast in rats.
S. Reilly (1999)
10.1037/0735-7044.118.2.365
Excitotoxic lesions of the gustatory thalamus spare simultaneous contrast effects but eliminate anticipatory negative contrast: evidence against a memory deficit.
S. Reilly (2004)
10.1002/CNE.903030303
Autonomic responses and efferent pathways from the insular cortex in the rat
Y. Yasui (1991)
10.1152/AJPREGU.1995.268.3.R666
Responses of single neurons in amygdala to interoceptive and exteroceptive stimuli in conscious cats.
M. Knuepfer (1995)
10.1016/0165-1838(85)90002-5
Convergence of vagal and gustatory afferent input within the parabrachial nucleus of the rat.
G. Hermann (1985)
10.1037/0735-7044.98.4.590
Taste agnosia following gustatory neocortex ablation: dissociation from odor and generality across taste qualities.
S. Kiefer (1984)
10.1007/s00429-010-0296-3
Functional neuroanatomy of the insular lobe
C. Stephani (2010)
10.1038/nature01808
Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex
L. Jasmin (2003)
10.1002/CNE.903110102
Organization of visceral and limbic connections in the insular cortex of the rat
G. V. Allen (1991)
10.1038/384159A0
A new brain region for coordinating speech articulation
N. Dronkers (1996)
10.1016/0006-8993(81)90913-6
Lateralized effects of bilateral frontal cortex lesions in rats
David A Ross (1981)
10.1152/JN.1980.44.3.440
Localization of cortical gustatory area in rats and its role in taste discrimination.
T. Yamamoto (1980)
10.1093/BRAIN/78.4.445
The insula; further observations on its function.
W. Penfield (1955)
10.1016/0006-8993(86)91635-5
The medial frontal cortex and gastric motility: Microstimulation results and their possible significance for the overall pattern of organization of rat frontal and parietal cortex
K. Hurley-Gius (1986)
10.1176/AJP.2007.164.2.318
Increased amygdala and insula activation during emotion processing in anxiety-prone subjects.
M. Stein (2007)
10.1016/J.EURPSY.2007.02.006
Insular cortex and neuropsychiatric disorders: a review of recent literature.
M. Nagai (2007)
10.1080/02699931.2011.565037
Early information processing biases in social anxiety
V. Miskovic (2012)
10.1016/j.bbr.2009.03.004
The functional neuroanatomy of depression: Distinct roles for ventromedial and dorsolateral prefrontal cortex
M. Koenigs (2009)
10.1023/B:NERE.0000010445.27905.aa
Biochemical Modulation of NMDA Receptors: Role in Conditioned Taste Aversion
B. Jiménez (2004)
10.1006/nlme.2000.3969
Effects of Excitotoxic Brain Lesions on Taste-Mediated Odor Learning in the Rat
N. Sakai (2001)
10.1523/JNEUROSCI.19-01-00420.1999
Pain Pathways Involved in Fear Conditioning Measured with Fear-Potentiated Startle: Lesion Studies
C. Shi (1999)
10.1002/CNE.903300310
Functional and anatomical organization of cardiovascular pressor and depressor sites in the lateral hypothalamic area. II. Ascending projections
G. V. Allen (1993)
10.1002/CNE.902410308
Cerebral cortical projections to the reticular regions around the trigeminal motor nucleus in the cat
Y. Yasui (1985)
10.1016/0166-4328(94)90097-3
Neural substrates for conditioned taste aversion in the rat
T. Yamamoto (1994)
10.1016/S1074-7427(03)00066-2
Cholinergic dependence of taste memory formation: Evidence of two distinct processes
R. Gutierrez (2003)
10.1523/JNEUROSCI.3272-03.2004
Posterior Triangular Thalamic Neurons Convey Nociceptive Messages to the Secondary Somatosensory and Insular Cortices in the Rat
C. Gauriau (2004)
10.1016/S0006-8993(00)01939-9
Bilateral lesions of the gustatory thalamus disrupt morphine- but not LiCl-induced intake suppression in rats: evidence against the conditioned taste aversion hypothesis
P. S. Grigson (2000)
10.1523/JNEUROSCI.19-21-j0002.1999
Molecular Mechanisms of Long-Term Potentiation in the Insular Cortex In Vivo
M. W. Jones (1999)
10.1101/LM.97605
Insular cortex is involved in consolidation of object recognition memory.
F. Bermúdez-Rattoni (2005)
10.1006/NLME.2000.3963
Calcitonin Gene-Related Peptide Released within the Amygdala Is Involved in Pavlovian Auditory Fear Conditioning
Laura H. Kocorowski (2001)
10.1002/(SICI)1096-9861(19981005)399:4<469::AID-CNE3>3.0.CO;2-#
Cascade projections from somatosensory cortex to the rat basolateral amygdala via the parietal insular cortex
C. J. Shi (1998)
Localization of pain-related brain activation: A metaanalysis of neuroimaging data. Hum Brain Mapp
E Duerden
10.1016/S0006-8993(97)00217-5
Transfer of information about taste from the nucleus of the solitary tract to the parabrachial nucleus of the pons
P. D. Lorenzo (1997)
10.1002/CNE.902570210
Thalamocortical and thalamo‐amygdaloid projections from the parvicellular division of the posteromedial ventral nucleus in the cat
Y. Yasui (1987)
10.1002/CNE.902240102
The organization of projections from the cortes, amygdala, and hypothalamus to the nucleus of the solitary tract in rat
D. van der Kooy (1984)
10.1016/s0165-0173(03)00172-3
The insula (Island of Reil) and its role in auditory processing: Literature review
D. Bamiou (2003)
10.1016/j.schres.2008.12.011
Mapping grey matter reductions in schizophrenia: An anatomical likelihood estimation analysis of voxel-based morphometry studies
A. Fornito (2009)
10.1016/B978-0-444-53860-4.00007-6
The insular cortex: a review.
R. Nieuwenhuys (2012)
10.1016/j.biopsych.2006.03.042
An Insular View of Anxiety
M. Paulus (2006)
10.1093/CERCOR/BHH076
The anatomy of spatial neglect based on voxelwise statistical analysis: a study of 140 patients.
H. Karnath (2004)
Role of the cerebral cortex in autonomic functions
D Cechetto (1990)
10.1037/0735-7044.102.1.3
Double dissociations of the effects of amygdala and insular cortex lesions on conditioned taste aversion, passive avoidance, and neophobia in the rat using the excitotoxin ibotenic acid.
L. T. Dunn (1988)
10.1523/JNEUROSCI.19-10-04169.1999
Dopamine Reuptake Inhibition in the Rostral Agranular Insular Cortex Produces Antinociception
A. Burkey (1999)
10.1037/h0034425
Latent inhibition.
R. Lubow (1973)
10.1037/0735-7044.107.6.1005
Parabrachial nucleus lesions and conditioned taste aversion: evidence supporting an associative deficit.
S. Reilly (1993)
10.1016/0163-1047(93)91145-D
Taste memory: the role of protein synthesis in gustatory cortex.
K. Rosenblum (1993)
10.1016/j.geb.2004.06.010
The somatic marker hypothesis: A neural theory of economic decision
A. Bechara (2005)
10.1016/S0361-9230(99)00218-X
Lateral parabrachial nucleus lesions in the rat: long- and short-duration gustatory preference tests
S. Reilly (2000)
10.1016/S0166-4328(96)00039-3
Ipsilateral connections between the gustatory cortex, amygdala and parabrachial nucleus are necessary for acquisition and retrieval of conditioned taste aversion in rats
E. Bielavská (1996)
10.1097/00001756-199704140-00009
Rat gustatory memory requires protein kinase C activity in the amygdala and cortical gustatory area
Y. Yasoshima (1997)
10.1152/JN.1953.16.4.343
Stimulation studies of insular cortex of Macaca mulatta.
B. L. Hoffman (1953)
10.1007/s00429-010-0255-z
A link between the systems: functional differentiation and integration within the human insula revealed by meta-analysis
F. Kurth (2010)
10.1126/SCIENCE.1145590
Inactivation of the Interoceptive Insula Disrupts Drug Craving and Malaise Induced by Lithium
Marco Contreras (2007)
10.1016/0196-9781(86)90233-0
Cardiovascular effects produced by microinjection of calcitonin gene-related peptide into the rat central amygdaloid nucleus
K. Q. Nguyen (1986)
10.1152/JN.00198.2004
Neural signature of taste familiarity in the gustatory cortex of the freely behaving rat.
A. Bahar (2004)
10.1016/S0163-1047(05)80046-9
Accelerating behavioral recovery after cortical lesions. I. Homotopic implants plus NGF.
M. Escobar (1994)
10.1146/ANNUREV.NEURO.25.032502.111311
The central autonomic nervous system: conscious visceral perception and autonomic pattern generation.
C. Saper (2002)
10.1046/j.1460-9568.2003.02551.x
The amygdalar circuit that acquires taste aversion memory differs from the circuit that extinguishes it
A. Bahar (2003)
Lubow R (1973) Latent inhibition
10.1523/JNEUROSCI.16-20-06612.1996
An Opioidergic Cortical Antinociception Triggering Site in the Agranular Insular Cortex of the Rat that Contributes to Morphine Antinociception
A. Burkey (1996)
10.1016/S0361-9230(01)00517-2
Lateral parabrachial nucleus lesions in the rat: neophobia and conditioned taste aversion
S. Reilly (2001)
10.1037/0735-7044.105.6.933
Central gustatory lesions: I. Preference and taste reactivity tests.
F. Flynn (1991)
10.1016/S0093-934X(03)00347-X
The contribution of the insula to motor aspects of speech production: A review and a hypothesis
H. Ackermann (2004)
10.1016/0031-9384(85)90350-6
Taste discriminations in rats lacking anterior insular gustatory neocortex
P. S. Lasiter (1985)
10.1016/S0031-9384(97)00352-1
Gustatory Thalamus Lesions in the Rat: III. Simultaneous Contrast and Autoshaping
S. Reilly (1997)
10.1016/j.neuroimage.2009.12.097
The impact of prior risk experiences on subsequent risky decision-making: The role of the insula
Gui Xue (2010)
Functional and anatomical organization of cardiovascular pressor and depressor sites in the lateral hypothalamic area
G Allen (1993)
10.1523/JNEUROSCI.20-18-07017.2000
The Role of Identified Neurotransmitter Systems in the Response of Insular Cortex to Unfamiliar Taste: Activation of ERK1–2 and Formation of a Memory Trace
Diego E. Berman (2000)
10.1016/S1074-7427(03)00061-3
Role of cholinergic system on the construction of memories: Taste memory encoding
M. I. Miranda (2003)
10.1111/j.1749-6632.1999.tb09275.x
Cortical Afferents to the Extended Amygdala
A. McDonald (1999)
10.1037//0735-7044.99.3.477
Thalamocortical relations in taste aversion learning: II. Involvement of the medial ventrobasal thalamic complex in taste aversion learning.
P. S. Lasiter (1985)
10.1002/CNE.902100207
Convergence of autonomic and limbic connections in the insular cortex of the rat
C. Saper (1982)
10.1016/S0006-8993(98)00931-7
The NMDA receptor antagonist CPP impairs conditioned taste aversion and insular cortex long-term potentiation in vivo.
M. Escobar (1998)
10.1016/j.neuroscience.2010.01.032
Efferent connections of an auditory area in the caudal insular cortex of the rat: anatomical nodes for cortical streams of auditory processing and cross-modal sensory interactions
A. Kimura (2010)
10.1046/j.1460-9568.2003.02608.x
Blockade of cortical muscarinic but not NMDA receptors prevents a novel taste from becoming familiar
R. Gutierrez (2003)
10.1097/00000658-197702000-00014
Effect of 50% distal small bowel resection on gastric emptying in Rhesus monkeys.
A. W. Hall (1977)
10.1006/nimg.2002.1087
Functional Neuroanatomy of Emotion: A Meta-Analysis of Emotion Activation Studies in PET and fMRI
K. L. Phan (2002)
10.1016/j.tics.2009.05.001
A common role of insula in feelings, empathy and uncertainty
T. Singer (2009)
10.1002/CNE.902620106
Amygdaloid connections with posterior insular and temporal cortical areas in the rat
A. McDonald (1987)
10.1152/JN.1985.53.6.1370
Gustatory responses of cortical neurons in rats. III. Neural and behavioral measures compared.
T. Yamamoto (1985)
10.1016/0304-3940(82)90238-5
Visceral cortex: A direct connection from prefrontal cortex to the solitary nucleus in rat
D. Kooy (1982)
10.1001/ARCHNEURPSYC.1956.02330210011001
The conduction of pain above the level of the thalamus opticus.
A. Biemond (1956)
10.1037/0735-7044.110.4.746
Gustatory thalamus lesions in the rat: II. Aversive and appetitive taste conditioning.
S. Reilly (1996)
10.1016/0006-8993(94)90890-7
Functional anatomy of taste perception in the human brain studied with positron emission tomography
S. Kinomura (1994)
10.1038/nature05405
Smell images and the flavour system in the human brain
G. Shepherd (2006)
10.1016/0959-4388(95)80023-9
Retrograde amnesia and memory consolidation: a neurobiological perspective
L. Squire (1995)
10.1523/JNEUROSCI.17-21-08443.1997
cAMP Response Element-Binding Protein in the Amygdala Is Required for Long- but not Short-Term Conditioned Taste Aversion Memory
R. Lamprecht (1997)
10.1016/S0987-7053(00)00227-6
Functional imaging of brain responses to pain. A review and meta-analysis (2000)
R. Peyron (2000)
10.1016/0031-9384(78)90245-7
Development of carbohydrate preference during water rationing: A specific hunger?
D. T. Corey (1978)
10.1126/SCIENCE.1089134
Does Rejection Hurt? An fMRI Study of Social Exclusion
N. Eisenberger (2003)
10.1002/(SICI)1096-9861(19991101)413:4<572::AID-CNE6>3.0.CO;2-S
Human forebrain activation by visceral stimuli
A. B. King (1999)
10.1016/S0168-0102(99)00129-7
An anterograde and retrograde tract-tracing study on the projections from the thalamic gustatory area in the rat: distribution of neurons projecting to the insular cortex and amygdaloid complex
M. Nakashima (2000)
10.1152/AJPREGU.1990.258.1.R245
Subcortical sites mediating sympathetic responses from insular cortex in rats.
D. Cechetto (1990)
10.1002/CNE.902900404
Calcitonin gene‐related peptide immunoreactivity in the visceral sensory cortex, thalamus, and related pathways in the rat
Y. Yasui (1989)
10.1037//0735-7044.108.6.1107
Influence of the noradrenergic state of the nucleus accumbens in basolateral amygdala mediated changes in neophobia of rats.
B. Roozendaal (1994)
10.1002/CNE.901780204
Amygdaloid projections to subcortical structures within the basal forebrain and brainstem in the rat and cat
J. E. Krettek (1978)
10.1002/CNE.902620104
Evidence for a viscerotopic sensory representation in the cortex and thalamus in the rat
D. Cechetto (1987)
10.1111/j.1460-9568.2007.05872.x
Effects of insular cortex lesions on conditioned taste aversion and latent inhibition in the rat
C. Roman (2007)
10.3389/fnbeh.2012.00010
Involvement of the insular cortex in regulating glucocorticoid effects on memory consolidation of inhibitory avoidance training
R. V. Fornari (2012)
10.1101/LM.72804
Enhancement of inhibitory avoidance and conditioned taste aversion memory with insular cortex infusions of 8-Br-cAMP: involvement of the basolateral amygdala.
M. I. Miranda (2004)
10.1016/j.neulet.2009.03.101
Functional organization of the human anterior insular cortex
I. Mutschler (2009)
10.1016/0306-4522(88)90339-9
Organization of the afferent connections of the mediodorsal thalamic nucleus in the rat, related to the mediodorsal-prefrontal topography
H. Groenewegen (1988)
10.1016/j.tics.2006.08.008
The empathic brain: how, when and why?
F. D. Vignemont (2006)
10.1016/j.brainres.2008.11.040
Taste, olfactory and trigeminal neophobia in rats with forebrain lesions
Jian-you Lin (2009)
10.1523/JNEUROSCI.5188-06.2007
Differential Spatial Representation of Taste Modalities in the Rat Gustatory Cortex
R. Accolla (2007)
Somato-motor, autonomic and electrocorticographic responses to electrical stimulation of rhinencephalic and other structures in primates, cat, and dog; a study of responses from the limbic, subcallosal, orbito-insular, piriform and temporal cortex, hippocampus-fornix and amygdala.
Kaada Br (1951)
10.1002/CNE.901500208
Ascending central gustatory pathways
R. Norgren (1973)
10.1037//0735-7044.105.6.944
Central gustatory lesions: II. Effects on sodium appetite, taste aversion learning, and feeding behaviors.
F. Flynn (1991)
10.1002/ANA.410310502
Functional reorganization of the brain in recovery from striatocapsular infarction in man
C. Weiller (1992)
10.1016/0006-8993(93)90300-C
Cardiac and sympathetic effects of middle cerebral artery occlusion in the spontaneously hypertensive rat
K. Butcher (1993)
10.1126/SCIENCE.2218534
The primate hippocampal formation: evidence for a time-limited role in memory storage.
S. Zola-Morgan (1990)
10.1016/0006-8993(75)90531-4
Projections of thalamic gustatory and lingual areas in the rat
R. Norgren (1975)
10.1002/mds.20191
Insular dopamine D2 receptors and novelty seeking personality in Parkinson's disease
V. Kaasinen (2004)
10.1016/S0166-2236(02)02211-7
Memory consolidation and the amygdala: a systems perspective
J. D. McGaugh (2002)
10.1093/acprof:oso/9780198523475.001.0001
[Conditioned taste aversion].
J. Bures̆ (1977)
10.1016/J.PARKRELDIS.2006.04.007
Are the insular cortex and cortisol implicated in Parkinsonian features?
M. Tops (2006)
10.1002/(SICI)1096-9861(19981005)399:4<440::AID-CNE2>3.0.CO;2-1
Cortical, thalamic, and amygdaloid connections of the anterior and posterior insular cortices
C. J. Shi (1998)
10.1111/j.1460-9568.2005.04440.x
Basolateral amygdala glutamatergic activation enhances taste aversion through NMDA receptor activation in the insular cortex
G. Ferreira (2005)
10.1016/j.neuron.2005.09.025
Contributions of the Amygdala to Emotion Processing: From Animal Models to Human Behavior
E. Phelps (2005)
10.1016/j.biopsych.2008.09.022
Functional Brain Correlates of Social and Nonsocial Processes in Autism Spectrum Disorders: An Activation Likelihood Estimation Meta-Analysis
A. Martino (2009)
10.1038/nrn2555
How do you feel — now? The anterior insula and human awareness
A. D. Craig (2009)
10.1016/S0006-8993(00)01990-9
Baroreceptive and somatosensory convergent thalamic neurons project to the posterior insular cortex in the rat
Z. Zhang (2000)
10.1002/CNE.902290310
The cortical projection of the basolateral amygdaloid nucleus in the rat: A retrograde fluorescent dye study
K. Sripanidkulchai (1984)
10.1093/CERCOR/12.4.376
Representation of pain and somatic sensation in the human insula: a study of responses to direct electrical cortical stimulation.
K. Ostrowsky (2002)
10.1101/LM.69704
Perirhinal cortex muscarinic receptor blockade impairs taste recognition memory formation.
R. Gutierrez (2004)
Provocation of obsessive-compulsive symptoms: a quantitative voxel-based meta-analysis of functional neuroimaging studies.
Jean-Yves Rotgé (2008)
10.1101/LM.53703
Conflicting processes in the extinction of conditioned taste aversion: behavioral and molecular aspects of latency, apparent stagnation, and spontaneous recovery.
Diego E. Berman (2003)
10.1016/j.nlm.2010.10.002
Involvement of the insular cortex in retention of conditioned taste aversion is not time dependent
Jimmy Stehberg (2011)
Role of the cerebral cortex in autonomic functions. In: Central Regulation of Autonomic Functions, edited by A
D Cechetto (1990)
10.1007/s002210050501
Processing of twitter-call fundamental frequencies in insula and auditory cortex of squirrel monkeys
A. Bieser (1998)
10.1016/J.COGBRAINRES.2004.06.005
The dynamics of cortico-amygdala and autonomic activity over the experimental time course of fear perception.
L. Williams (2004)
10.1016/0031-9384(83)90201-9
Autonomic and somatomotor effects of amygdala central N. stimulation in awake rabbits
C. Applegate (1983)
10.1016/j.neuroimage.2009.05.024
Functional neuroanatomy of autonomic regulation
D. Cechetto (2009)
10.1006/nlme.1995.1051
Latent Inhibition in Conditioned Taste Aversion: The Roles of Stimulus Frequency and Duration and the Amount of Fluid Ingested During Preexposure
G. Delacasa (1995)
10.1101/LM.3.1.31
Transient expression of c-Fos in rat amygdala during training is required for encoding conditioned taste aversion memory.
R. Lamprecht (1996)
10.1002/CNE.903590204
Efferent projections of the paraventricular thalamic nucleus in the rat
M. Moga (1995)
10.1126/SCIENCE.1585183
Modality-specific retrograde amnesia of fear.
J. J. Kim (1992)
10.1016/0165-0173(84)90012-2
Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat
C. Fulwiler (1984)
10.1016/S0361-9230(98)00173-7
The parabrachial nucleus and conditioned taste aversion
S. Reilly (1999)
10.1007/BF00580694
A study of the amygdaloid defence reaction showing the value of Althesin anaesthesia in studies of the functions of the fore-brain in cats
R. J. Timms (2004)
10.1007/s00429-010-0252-2
Anterior insula activations in perceptual paradigms: often observed but barely understood
P. Sterzer (2010)
10.1007/s00429-010-0266-9
Taste representation in the human insula
D. Small (2010)
10.1523/JNEUROSCI.1336-08.2008
Corticotropin-Releasing Factor in the Basolateral Amygdala Enhances Memory Consolidation via an Interaction with the β-Adrenoceptor–cAMP Pathway: Dependence on Glucocorticoid Receptor Activation
B. Roozendaal (2008)
10.1016/0306-4522(78)90102-1
Projections from the nucleus of the solitary tract in the rat
R. Norgren (1978)
Amygdala and insula response to emotional images in patients with generalized social anxiety disorder.
S. G. Shah (2009)
10.1016/0361-9230(82)90040-5
Insular cortex projection to the nucleus of the solitary tract and brainstem visceromotor regions in the mouse
M. Shipley (1982)
10.1016/S0166-4328(01)00329-1
In vivo effects of intracortical administration of NMDA and metabotropic glutamate receptors antagonists on neocortical long-term potentiation and conditioned taste aversion
M. Escobar (2002)
10.1016/0014-4886(81)90020-0
Psychic ageusia in rats lacking gustatory neocortex
J. Braun (1981)
10.1016/j.neubiorev.2009.06.002
The anterior insula in autism: Under-connected and under-examined
L. Uddin (2009)
10.1037//0735-7044.111.3.633
Gustatory functions, sodium appetite, and conditioned taste aversion survive excitotoxic lesions of the thalamic taste area.
G. Scalera (1997)
10.1016/j.tins.2008.09.009
The hidden island of addiction: the insula
N. Naqvi (2009)
10.1016/0014-4886(87)90109-9
Sensory input to single neurons in the amygdala of the cat
I. Schuetze (1987)
10.1016/S0166-4328(01)00302-3
Conditioned taste aversion as a learning and memory paradigm
H. Welzl (2001)
10.1093/CERCOR/10.3.206
The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans.
D. Ongür (2000)
10.1023/A:1025048802629
The Emotional Brain, Fear, and the Amygdala
Joseph E LeDoux (2004)
10.1111/j.1528-1167.2010.02755.x
Anatomofunctional organization of the insular cortex: A study using intracerebral electrical stimulation in epileptic patients
Afif Afif (2010)
10.1016/j.neuroimage.2007.03.071
The cognitive control network: Integrated cortical regions with dissociable functions
Michael W. Cole (2007)
10.1016/S0006-8993(02)03159-1
Time-limited role of the hippocampus in the memory for trace eyeblink conditioning in mice
K. Takehara (2002)
10.1152/JAPPLPHYSIOL.00852.2003
Functional magnetic resonance signal changes in neural structures to baroreceptor reflex activation.
L. Henderson (2004)
10.1016/S0006-8993(99)02134-4
Long-term potentiation in the insular cortex enhances conditioned taste aversion retention
M. Escobar (2000)
10.1038/nrn894
How do you feel? Interoception: the sense of the physiological condition of the body
A. D. Craig (2002)
10.1037//0735-7044.110.5.1074
Basolateral amygdala lesions block glucocorticoid-induced modulation of memory for spatial learning.
B. Roozendaal (1996)
10.1016/S0006-8993(97)00284-9
Characterization, distribution and lateralization of baroreceptor-related neurons in the rat insular cortex
Z. Zhang (1997)
10.1002/CNE.902570206
A role of insular cortex in cardiovascular function
D. Ruggiero (1987)
10.1016/0006-8993(91)90616-4
Insular cortex and amygdala lesions differentially affect acquisition on inhibitory avoidance and conditioned taste aversion
F. Bermúdez-Rattoni (1991)
10.1152/PHYSREV.1963.43.1.68
Effects of cortical stimulation and lesions on cardiovascular function.
E. Hoff (1963)



This paper is referenced by
10.1007/s11060-016-2120-2
Surgery of insular and paralimbic diffuse low-grade gliomas: technical considerations
K. Michaud (2016)
10.3389/fphys.2019.00330
The Role of the Rodent Insula in Anxiety
Maxs Méndez-Ruette (2019)
10.1016/j.pmn.2019.06.013
Supremacy of Auditory Versus Visual Input in Somatic Empathy and Perceived Pain Level.
Sepideh Agahi (2019)
10.3389/fnbeh.2016.00050
Distinctive Roles of 5-aza-2′-deoxycytidine in Anterior Agranular Insular and Basolateral Amygdala in Reconsolidation of Aversive Memory Associated with Morphine in Rats
Peng Liu (2016)
10.1016/j.neuropsychologia.2019.107290
The behavioral and neural basis of foreign language effect on risk-taking
Liling Zheng (2020)
10.1101/633263
Sustained perturbation in functional connectivity induced by cold pain
Elena Makovac (2019)
10.1523/JNEUROSCI.0752-19.2019
Activity of Insula to Basolateral Amygdala Projecting Neurons is Necessary and Sufficient for Taste Valence Representation
Haneen Kayyal (2019)
10.1016/j.ynpai.2020.100052
Chronic inflammatory pain alters alcohol-regulated frontocortical signaling and associations between alcohol drinking and thermal sensitivity
M. Adrienne McGinn (2020)
10.3389/fnbeh.2015.00108
Noradrenergic activation of the basolateral amygdala enhances object recognition memory and induces chromatin remodeling in the insular cortex
H. Beldjoud (2015)
10.24377/RESEARCHONLINE.LJMU.AC.UK.00009599
Individual differences in behavioural and physiological responses to affective touch
Cj Haggarty (2018)
10.1007/s12264-016-0016-y
Insular Cortex is Critical for the Perception, Modulation, and Chronification of Pain
Changbo Lu (2016)
10.3389/fnbeh.2016.00181
Goal-Directed Behavior and Instrumental Devaluation: A Neural System-Level Computational Model
Francesco Mannella (2016)
10.3389/fnbeh.2015.00164
The insula modulates arousal-induced reluctance to try novel tastes through adrenergic transmission in the rat
S. Rojas (2015)
10.3389/fphar.2020.00743
Postretrieval Microinjection of Baclofen Into the Agranular Insular Cortex Inhibits Morphine-Induced CPP by Disrupting Reconsolidation
Kuisheng Sun (2020)
10.1093/brain/awu305
Reduced anterior insula, enlarged amygdala in alcoholism and associated depleted von Economo neurons.
V. Senatorov (2015)
10.1016/j.neuroimage.2014.12.003
Rotarod training in mice is associated with changes in brain structure observable with multimodal MRI
J. Scholz (2015)
10.1016/j.neuroimage.2015.08.014
The left amygdala: A shared substrate of alexithymia and empathy
K. S. Goerlich-Dobre (2015)
10.1016/j.neuropharm.2018.08.018
Basolateral amygdala noradrenergic activity is required for enhancement of object recognition memory by histone deacetylase inhibition in the anterior insular cortex
Yanfen Chen (2018)
10.3389/fnana.2018.00030
Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum
H. Jiang (2018)
10.1080/00207454.2020.1716751
The effect of insular cortex lesion on hyperacusis-like behavior in rats
M. Karimi (2020)
Semantic Scholar Logo Some data provided by SemanticScholar