Online citations, reference lists, and bibliographies.
← Back to Search

Malign Plevral Mezotelyoma Hastalarında Destek Tedavisi Ve Plöredezin Karşılaştırılması

A. C. Tanrıkulu, Özlem Abakay, C. Sezgi, H. Şen, A. Abakay
Published 2012 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Objectives: Malignant Pleural Mesothelioma (MPM) is a poor prognosis cancer that affects pleura. This study was designed for examination of the differences between MPM patients which who were received only supportive treatment and supportive treatment plus pleurodesis. Materials and methods: The files of 96 MPM patients were analyzed retrospectively who were followed up in Dicle University Medical Faculty Hospital. Age, gender, exposure of asbestos, diagnostic methods, histopathological types and treatment regimens were recorded. Results: The mean age of 96 MPM patients were 60.4 p 12.6 years. The sixty-three (65.6%) patients were male and 33 (34.4%) were female. A total 75 (78.1%) patients have environmental asbestos exposure and mean environmental asbestos exposure time was 33 years. The epithelial type of pleural mesothelioma was determined in 63 patients. Pleural fluid cytology was positive in 30 patients. The most detected symptom was dyspnea which was determined in 91 cases. Thirty patients were taken only supportive treatment and 66 were taken supportive treatment plus pleurodesis. The median survival time was 10 months in the total of the two groups. Median survival was 10.7 months, in the group that treated with pleurodesis and 9.1 months in the group that not treated with pleurodesis. However, this difference was not statistically significant (p = 0.35). Conclusions: Malignant pleural mesothelioma is an aggressive form of cancer which is resistant to many therapeutic options. Progressive dyspnea is primary symptom in these patients and often depends on the pleural fluid. Pleurodesis is an option to control the fluid. However, there is not any contribution on survival, alone. Extensive investigations are needed on this topic.
This paper references
10.1200/JCO.1988.6.3.527
Malignant pleural mesothelioma: a disease unaffected by current therapeutic maneuvers.
A. Alberts (1988)
10.1016/J.LUNGCAN.2006.11.005
A retrospective analysis of malignant pleural mesothelioma patients treated either with chemotherapy or best supportive care between 1990 and 2005 A single institution experience.
M. Metintas (2007)
10.1183/09031936.97.10071648
Pleurodesis: state of the art.
F. Rodríguez-Panadero (1997)
10.1183/09031936.98.12040972
Malignant pleural mesothelioma.
C. Boutin (1998)
The incidence of mesothelioma has not decreased for the last twenty years in Southeast region of Anatolia.
A. I. Carkanat (2011)
Malignant Pleural Mesothelioma Caused by Environmental Exposure to Asbestos in the Southeast of Turkey : CT Findings in 117 Patients
H. Leblebı̇cı̇a (2000)
10.1097/MCP.0b013e328302851d
Malignant mesothelioma 2008
M. Zervos (2008)
10.1378/CHEST.102.3.790
Malignant pleural mesothelioma due to environmental mineral fiber exposure in Turkey. Analysis of 135 cases.
Z. Selçuk (1992)
10.1016/S0169-5002(99)00044-6
Prognostic value of the serum tumour markers Cyfra 21-1 and tissue polypeptide antigen in malignant mesothelioma.
H. Schouwink (1999)
10.1510/icvts.2010.256271
Is pleurectomy and decortication superior to palliative care in the treatment of malignant pleural mesothelioma?
I. Zahid (2011)
10.1378/CHEST.70.1.43
Pleural calcification associated with exposure to chrysotile asbestos in southeast Turkey.
S. Yazicioglu (1976)
10.7326/0003-4819-120-1-199401010-00010
Chemical Pleurodesis for Malignant Pleural Effusions
P. Walker-Renard (1994)
10.1136/thx.39.4.255
Malignant mesothelioma of the pleura: a study of 52 treated and 64 untreated patients.
M. Law (1984)
10.1016/S1010-7940(02)00273-7
The management of malignant pleural mesothelioma; single centre experience in 10 years.
T. Aziz (2002)
10.1378/CHEST.122.6.2224
Malignant mesothelioma due to environmental exposure to asbestos: follow-up of a Turkish cohort living in a rural area.
S. Metintaş (2002)
10.1177/030089161209800206
Effects of Combined Therapies on the Survival of Pleural Mesothelioma Patients Treated in Brescia, 1982–2006
Pietro Gino Barbieri (2012)
10.1378/CHEST.116.2.504
Advances in the treatment of malignant pleural mesothelioma.
D. Sterman (1999)
Environmental malignant pleural mesothelioma in Southeast Turkey.
A. C. Tanrıkulu (2006)
10.1016/S0954-6111(99)90318-9
Environmental asbestos exposure and malignant pleural mesothelioma.
M. Metintas (1999)
10.1159/000056289
Incidence of Malignant Pleural Mesothelioma due to Environmental Asbestos Fiber Exposure in the Southeast of Turkey
A. Şenyiğit (2000)



Semantic Scholar Logo Some data provided by SemanticScholar