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Shape-, Size- And Structure-controlled Synthesis And Biocompatibility Of Iron Oxide Nanoparticles For Magnetic Theranostics

Wensheng Xie, Zhenhu Guo, F. Gao, Q. Gao, D. Wang, Bor-shuang Liaw, Q. Cai, Xiaodan Sun, Xiumei Wang, Lingyun Zhao
Published 2018 · Materials Science, Medicine

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In the past decade, iron oxide nanoparticles (IONPs) have attracted more and more attention for their excellent physicochemical properties and promising biomedical applications. In this review, we summarize and highlight recent progress in the design, synthesis, biocompatibility evaluation and magnetic theranostic applications of IONPs, with a special focus on cancer treatment. Firstly, we provide an overview of the controlling synthesis strategies for fabricating zero-, one- and three-dimensional IONPs with different shapes, sizes and structures. Then, the in vitro and in vivo biocompatibility evaluation and biotranslocation of IONPs are discussed in relation to their chemo-physical properties including particle size, surface properties, shape and structure. Finally, we also highlight significant achievements in magnetic theranostic applications including magnetic resonance imaging (MRI), magnetic hyperthermia and targeted drug delivery. This review provides a background on the controlled synthesis, biocompatibility evaluation and applications of IONPs as cancer theranostic agents and an overview of the most up-to-date developments in this area.
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Biocompatibility assessment of sub-5 nm silica-coated superparamagnetic iron oxide nanoparticles in human stem cells and in mice for potential application in nanomedicine.
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EDTA-grafted Cu2+-doped superparamagnetic nanoparticles: facile novel synthesis and their structural and magnetic characterizations
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Artificial Saliva: Challenges and Future Perspectives for the Treatment of Xerostomia
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Synthesis and Characterization of Oleic Acid Coated Magnetic Nanoparticles for Hyperthermia Applications
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A Carbon-Cloth Anode Electroplated with Iron Nanostructure for Microbial Fuel Cell Operated with Real Wastewater
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Irregularly Shaped Iron Nitride Nanoparticles as a Potential Candidate for Biomedical Applications: From Synthesis to Characterization
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pH Dependent Drug Release of Silibinin, a Polyphenol Conjugated with Magnetic Nanoparticle Against the Human Colon Cancer Cell
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Magnetite Nanoparticles and Essential Oils Systems for Advanced Antibacterial Therapies
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Gas-phase synthesis of iron oxide nanoparticles for improved magnetic hyperthermia performance
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Electrochemically synthesized γ-Fe2O3 nanoparticles as peptide carriers and sensitive and reproducible SERS biosensors. Comparison of adsorption on γ-Fe2O3 versus Fe
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X‐Ray‐Induced Persistent Luminescence Promotes Ultrasensitive Imaging and Effective Inhibition of Orthotopic Hepatic Tumors
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Unravelling the Thermal Decomposition Parameters for The Synthesis of Anisotropic Iron Oxide Nanoparticles
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Shape Anisotropic Iron Oxide-Based Magnetic Nanoparticles: Synthesis and Biomedical Applications
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Hyperbranched lipopolymer-folate-stabilized manganese ferrite nanoparticles for the water-soluble targeted MRI contrast agent
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Liquid-Phase Synthesis of Iron Oxide Nanostructured Materials and Their Applications.
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Biosynthesis of Zinc oxide nanoparticles from essential oil of Eucalyptus globulus with antimicrobial and anti-biofilm activities
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Exploiting Nanomaterial-mediated Autophagy for Cancer Therapy.
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Iron Oxide Nanoparticle-Induced Autophagic Flux Is Regulated by Interplay between p53-mTOR Axis and Bcl-2 Signaling in Hepatic Cells
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10.3390/nano9091195
Application of Nanoparticles and Nanomaterials in Thermal Ablation Therapy of Cancer
Zhannat Ashikbayeva (2019)
10.1016/j.jconrel.2020.06.026
Taking advantage of cellular uptake of ferritin nanocages for targeted drug delivery.
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10.3390/nano9111565
In Vitro and In Vivo Antioxidant Activity of the New Magnetic-Cerium Oxide Nanoconjugates
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10.3390/nano9101480
Purification of Fluorescently Derivatized N-Glycans by Magnetic Iron Nanoparticles
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10.1016/j.ijhydene.2020.04.111
Visible light-driven hydrogen evolution by using mesoporous carbon nitride-metal ferrite (MFe2O4/mpg-CN; M: Mn, Fe, Co and Ni) nanocomposites as catalysts
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Pharmaceutical Applications of Iron-Oxide Magnetic Nanoparticles
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Magnetic heating of nanoparticles as a scalable cryopreservation technology for human induced pluripotent stem cells
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Surface Modification of Magnetic Nanoparticles by Carbon-Coating Can Increase Its Biosafety: Evidences from Biochemical and Neurobehavioral Tests in Zebrafish
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Ultrathin surface coated water-soluble cobalt ferrite nanoparticles with high magnetic heating efficiency and rapid in vivo clearance.
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Using magnetic particle imaging systems to localize and guide magnetic hyperthermia treatment: tracers, hardware, and future medical applications
Prashant Chandrasekharan (2020)
10.1016/j.mtnano.2020.100084
Magnetic nanoparticles in regenerative medicine: what of their fate and impact in stem cells?
A. V. D. Walle (2020)
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