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Polymeric Nanomaterials – Synthesis, Functionalization And Applications In Diagnosis And Therapy

J. Rieger, C. Jérôme, R. Jérôme, R. Auzély-Velty
Published 2007 · Materials Science

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The sections in this article are Introduction Polymer Materials Used for the Synthesis of Nanoparticles Natural Polymers Degradable Synthetic Polymers Nondegradable Synthetic Polymers PEO Preparation of Polymeric Nanoparticles Preparation of Nanospheres from Preformed Polymers Emulsion-evaporation Salting-out Emulsification-diffusion Nanoprecipitation Synthesis of Nanospheres by In Situ Polymerization Preparation of Nanocapsules Surface Functionalization Functionalization with Biological (Macro)molecules Functionalization with Specific Ligands: Specific Interaction through Biological Recognition Mono- or Oligosaccharides (Carbohydrates) Folate Receptor Antibodies Biotin Strategies for Surface Modification Adsorption on Preformed Nanoparticles Functional Surfactants as Stabilizers and Surface Modifiers Emulsion, Miniemulsion or Dispersion Polymerization Covalent Linking of Functional Molecules to Preformed Nanoparticles Analytical Techniques for Surface Modification Physicochemical Techniques Biological Assays/Methods Applications Drug Delivery Systems [141] Routes of Administration Therapeutic Applications of Nanoparticles Triggered Release Diagnosis Fluorescence Labeling of Polymeric Nanoparticles Contrast Agents for MRI Magnetic Nanoparticles for In Vitro Assays Electron Dense Agents for Transmission Electron Microscopy (TEM) Radiolabeled Nanoparticles Conclusion and Perspectives
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