Online citations, reference lists, and bibliographies.
← Back to Search

Determination Of Tablet Strength By The Diametral-compression Test.

J. T. Fell, J. Newton
Published 1970 · Chemistry, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
The strength of lactose tablets has been measured by application of the diametral-compression test. The relative value of tensile, compressive, and shear stresses within the tablet varies, depending on the characteristics of the tablets and the surface providing the applied compression. It has been shown that to obtain reproducible results for the strength of tablets prepared at a given compression force, the tablet must break in such a manner that the tensile stress is the major stress. For a given tablet, this may require the placing of suitable padding material between the tablet and the compressing surfaces. Assessment of the type of failure can be made visually and under the correct conditions, the results expressed as a tensile strength. There are, however, a range of conditions which ensure tensile failure resulting in different values for the tensile strength. These values are characteristic of the tablet and test conditions and are not absolute values of tensile strength.
This paper references

This paper is referenced by
Effects of interacting variables on the tensile strengths and disintegration times of paracetamol tablets
A. B. Bangudu (1985)
Effect of compression speed and pressure on the physical characteristics of maltodextrin tablets.
M. C. Monedero (1998)
Production of inert cushioning beads: effect of excipients on the physicomechanical properties of freeze-dried beads containing microcrystalline cellulose produced by extrusion-spheronization.
Y. Habib (2002)
Modeling of adhesion in tablet compression. II. Compaction studies using a compaction simulator and an instrumented tablet press.
J. J. Wang (2004)
Modulating the Dissolution and Mechanical Properties of Resveratrol by Cocrystallization
Hongyan He (2017)
Instrumentation of tableting machines : high speed compaction investigation through simulation and radial die-wall pressure monitoring
Abdel-Hamid Abd-Rabo (2011)
Mechanistic evaluation of binary effects of magnesium stearate and talc as dissolution retardants at 85% drug loading in an experimental extended-release formulation.
T. Duerig (1997)
Compression and Mechanical Properties of Tablet Formulations Containing Corn, Sweet Potato, and Cocoyam Starches as Binders
O. Odeku (2005)
Oral Controlled-Release Solid Dosage Forms, Use of Novel Polymer and Unconventional Polymer Blends
R. Ali (2015)
Effect of Moisture on the Compressibility and Compactibility of Sodium Starch Glycolate
P. Young (2007)
Tablet strength testing
J. F. Bavitz (1974)
Evaluation of Citrus Fibers as a Tablet Excipient
M. Cespi (2013)
Formulation and development of matrix tablets of tramadol using katira gum as release modifier.
I. Singh (2010)
How do roll compaction/dry granulation affect the tableting behaviour of inorganic materials? Microhardness of ribbons and mercury porosimetry measurements of tablets.
F. Freitag (2004)
Calcium phosphates in pharmaceutical tableting
P. Schmidt (2005)
Xanthan gum as a rate-controlling polymer for the development of alcohol resistant matrix tablets and mini-tablets.
A. Lazzari (2018)
High-shear granulation of high-molecular weight hypromellose: effects of scale-up and process parameters on flow and compaction properties
Peter Grdešič (2018)
A Quantitative Correlation of the Effect of Density Distributions in Roller-Compacted Ribbons on the Mechanical Properties of Tablets Using Ultrasonics and X-ray Tomography
I. Akseli (2011)
A New Method of Producing Monoclinic Paracetamol Suitable for Direct Compression
A. G. Ogienko (2011)
Effect of process variables on physicomechanical properties of the agglomerates obtained by spherical crystallization technique
M. Maghsoodi (2011)
Towards a better understanding of dry binder functionality
Oscar-Rupert Arndt (2018)
Mechanical properties and drug release of venlafaxine HCl solid mini matrices prepared by hot-melt extrusion and hot or ambient compression
Theodoros Avgerinos (2018)
Evaluation of an external lubrication system implemented in a compaction simulator.
Cedrine de Backere (2020)
Effect of the surface free energy of materials on the lamination tendency of bilayer tablets.
Kitti Papós (2015)
Resveratrol cocrystals with enhanced solubility and tabletability.
Zhengzheng Zhou (2016)
Computational intelligence modelling of pharmaceutical tabletting processes using bio-inspired optimization algorithms
Hossam M. Zawbaa (2018)
Effects of the granule composition on the compaction behavior of deformable dry granules
B. Mitra (2016)
The relation between the compaction pressure,porosity and tensile strength of compacted powders
J. Newton (1974)
Compression Characteristics of Granulated Materials. VII. The Effect of Intragranular Binder Distribution on the Compactibility of Some Lactose Granulations
M. Wikberg (2004)
The compressive to tensile strength ratio of pharmaceutical compacts
J. Newton (1993)
The effects of compression rate and force on the compaction properties of different viscosity grades of hydroxypropylmethylcellulose 2208
A. Nokhodchi (1996)
Characterization of compressibility and compactibility of poly(ethylene oxide) polymers for modified release application by compaction simulator.
L. Yang (1996)
See more
Semantic Scholar Logo Some data provided by SemanticScholar