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Bone Tissue Engineering Via Carbon-Based Nanomaterials.

Zhili Peng, T. Zhao, Yiqun Zhou, Shanghao Li, Jiaojiao Li, R. Leblanc
Published 2020 · Medicine, Materials Science

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Bone tissue engineering (BTE) has received significant attention due to its enormous potential in treating critical-sized bone defects and related diseases. Traditional materials such as metals, ceramics, and polymers have been widely applied as BTE scaffolds; however, their clinical applications have been rather limited due to various considerations. Recently, carbon-based nanomaterials attract significant interests for their applications as BTE scaffolds due to their superior properties, including excellent mechanical strength, large surface area, tunable surface functionalities, high biocompatibility as well as abundant and inexpensive nature. In this article, recent studies and advancements on the use of carbon-based nanomaterials with different dimensions such as graphene and its derivatives, carbon nanotubes, and carbon dots, for BTE are reviewed. Current challenges of carbon-based nanomaterials for BTE and future trends in BTE scaffolds development are also highlighted and discussed.
This paper references
10.1002/ZAAC.19623160303
Das Adsorptionsverhalten sehr dünner Kohlenstoff‐Folien
H. Boehm. (1962)
Phosphates and phosphoric acid.
P. Becker (1983)
P. Becker (1983)
10.1038/318162a0
C60: Buckminsterfullerene
H. Kroto (1985)
On Biomineralization
Heinz A. Lowenstam (1989)
10.1038/347354a0
Solid C60: a new form of carbon
W. Krätschmer (1990)
10.1351/pac199163070961
Hierarchical structure of collagen composite systems: lessons from biology
E. Baer (1991)
10.1097/00010694-196109000-00021
Calcification in Biological Systems
E. Bonucci (1992)
E. Bonucci (1992)
10.1038/363605A0
Cobalt-catalysed growth of carbon nanotubes with single-atomic-layer walls
D. Bethune (1993)
10.1038/363603A0
Single-shell carbon nanotubes of 1-nm diameter
S. Iijima (1993)
D. BuckleyJ. (1993)
10.1097/00004669-199701000-00009
Biomaterials Science: An Introduction to Materials in Medicine
B. Ratner (1996)
10.1016/0142-9612(96)85754-1
Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers.
K. Athanasiou (1996)
10.1146/ANNUREV.MATSCI.28.1.271
THE MATERIAL BONE: Structure-Mechanical Function Relations
S. Weiner (1998)
10.1002/(SICI)1097-4636(19991205)47:3<324::AID-JBM6>3.0.CO;2-Y
In vitro analysis of biodegradable polymer blend/hydroxyapatite composites for bone tissue engineering.
K. Marra (1999)
10.1089/107632700418083
Fundamentals of biomechanics in tissue engineering of bone.
K. Athanasiou (2000)
10.1126/SCIENCE.1060928
Carbon Nanotubes--the Route Toward Applications
R. Baughman (2002)
10.1021/JA0355574
Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-* versus 1O2.
Y. Yamakoshi (2003)
10.22203/ECM.V005A01
Biodegradable synthetic polymers for tissue engineering.
P. Gunatillake (2003)
10.1089/107632703762687555
Poly(D,L-lactic acid)-poly(ethylene glycol)-monomethyl ether diblock copolymers control adhesion and osteoblastic differentiation of marrow stromal cells.
E. Lieb (2003)
10.1126/SCIENCE.1102896
Electric Field Effect in Atomically Thin Carbon Films
K. Novoselov (2004)
10.1002/MABI.200400026
Bone tissue engineering: state of the art and future trends.
A. Salgado (2004)
10.1021/JA040082H
Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments.
Xiaoyou Xu (2004)
D. RatnerB. (2004)
10.1007/S10047-005-0292-1
Bone tissue engineering with porous hydroxyapatite ceramics
H. Yoshikawa (2005)
10.1016/J.BIOMATERIALS.2004.04.024
Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation.
Christopher G. Williams (2005)
10.1073/pnas.0407356102
Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation
B. Keselowsky (2005)
10.1021/CM0500399
A Bone Mimic Based on the Self-Assembly of Hydroxyapatite on Chemically Functionalized Single-Walled Carbon Nanotubes
Bin Zhao (2005)
10.1016/J.BIOMATERIALS.2005.11.025
45S5 Bioglass-derived glass-ceramic scaffolds for bone tissue engineering.
Qi-zhi Chen (2006)
10.1021/JA062677D
Quantum-sized carbon dots for bright and colorful photoluminescence.
Ya-Ping Sun (2006)
10.1021/NL051861E
Bone cell proliferation on carbon nanotubes.
L. Zanello (2006)
10.1021/JA063303N
Control of sp2/sp3 carbon ratio and surface chemistry of nanodiamond powders by selective oxidation in air.
S. Osswald (2006)
10.1021/NL060162E
Cellular toxicity of carbon-based nanomaterials.
A. Magrez (2006)
10.1016/j.cell.2006.06.044
Matrix Elasticity Directs Stem Cell Lineage Specification
A. Engler (2006)
10.1007/S10856-006-0435-9
Gene activation by bioactive glasses
G. Jell (2006)
10.1016/J.MSEC.2005.03.009
Apatite formation on carbon nanotubes
T. Akasaka (2006)
10.1039/B604308A
Supramolecular [60]fullerene chemistry on surfaces.
D. Bonifazi (2007)
10.1038/NMAT1849
The rise of graphene.
Andre K. Geim (2007)
10.1002/ANIE.200701271
Fluorescent carbon nanoparticles derived from candle soot.
Haipeng Liu (2007)
10.1021/JA073527L
Carbon dots for multiphoton bioimaging.
L. Cao (2007)
10.1016/J.MSER.2007.05.001
Bone structure and formation: A new perspective
M. Olszta (2007)
10.1016/J.TOXLET.2007.08.009
A new approach to the toxicity testing of carbon-based nanomaterials--the clonogenic assay.
E. Herzog (2007)
10.1002/smll.200700670
Carbon nanotubes with high bone-tissue compatibility and bone-formation acceleration effects.
Yuki Usui (2008)
10.1016/j.bone.2008.04.013
In vivo biocompatibility of ultra-short single-walled carbon nanotube/biodegradable polymer nanocomposites for bone tissue engineering.
B. Sitharaman (2008)
10.1007/S10856-007-3196-1
Electrophoretic deposition of HA/MWNTs composite coating for biomaterial applications
Changjian Lin (2008)
10.4065/83.9.1032
Bisphosphonates: mechanism of action and role in clinical practice.
M. Drake (2008)
10.1039/b812420e
Facile preparation of low cytotoxicity fluorescent carbon nanocrystals by electrooxidation of graphite.
Qiao-Ling Zhao (2008)
10.1002/ADEM.200700241
Multi‐walled Carbon Nanotube‐Reinforced Hydroxyapatite Layers on Ti6Al4V Medical Implants by Electrophoretic Deposition (EPD)
C. Kaya (2008)
10.1002/ADMA.200800757
Mechanically Strong, Electrically Conductive, and Biocompatible Graphene Paper
H. Chen (2008)
10.1016/J.BIOMATERIALS.2007.09.021
Multiwall carbon nanotube scaffolds for tissue engineering purposes.
A. Abarrategi (2008)
10.1111/j.1365-2818.2008.02142.x
Virtual histology by means of high‐resolution X‐ray CT
V. Cnudde (2008)
10.1002/term.63
Bone morphogenetic proteins in tissue engineering: the road from the laboratory to the clinic, part I (basic concepts)
P. C. Bessa (2008)
H. Yoshikawa (2008)
M. Bacakova (2008)
10.1021/JP905912N
Fluorescent Carbon Nanoparticles: Synthesis, Characterization, and Bioimaging Application
S. Ray (2009)
10.1039/B812943F
One-step synthesis of fluorescent carbon nanoparticles by laser irradiation
S. Hu (2009)
10.1021/ja809073f
Electrochemiluminescence of water-soluble carbon nanocrystals released electrochemically from graphite.
Liyan Zheng (2009)
10.1021/nn900252j
Suppression of human bone morphogenetic protein signaling by carboxylated single-walled carbon nanotubes.
Qingxin Mu (2009)
10.1021/ES8031506
Microbial cytotoxicity of carbon-based nanomaterials: implications for river water and wastewater effluent.
Seoktae Kang (2009)
10.1126/science.1171245
Large-Area Synthesis of High-Quality and Uniform Graphene Films on Copper Foils
Xuesong Li (2009)
10.3390/ma2030833
Biodegradable Polymers in Bone Tissue Engineering
R. Kroeze (2009)
10.1021/JP9085969
Carbon Dots as Nontoxic and High-Performance Fluorescence Imaging Agents.
Sheng-Tao Yang (2009)
10.1007/S10853-009-3770-7
A review on biodegradable polymeric materials for bone tissue engineering applications
M. Sabir (2009)
10.1021/nl8030746
Multiwalled carbon nanotubes specifically inhibit osteoclast differentiation and function.
N. Narita (2009)
10.3390/ma2030790
Metallic Scaffolds for Bone Regeneration
Kelly Alvarez (2009)
10.1016/j.actbio.2009.05.005
Mechanical and in vitro biological performances of hydroxyapatite-carbon nanotube composite coatings deposited on Ti by aerosol deposition.
B. Hahn (2009)
10.1166/JNN.2009.NS26
Nanodiamond as promising material for bone tissue engineering.
L. Grausova (2009)
10.1016/s1351-4180(09)70357-5
Carbon materials for catalysis
P. Serp (2009)
10.1016/J.MSEC.2008.05.009
Preparation and characterization of a novel hydroxyapatite/carbon nanotubes composite and its interaction with osteoblast-like cells
Jinling Xu (2009)
10.1021/ja904843x
Carbon dots for optical imaging in vivo.
Sheng-Tao Yang (2009)
P. Serp (2009)
10.1007/978-1-60761-579-8
Carbon Nanotubes
G. Ostojic (2010)
10.1038/NPHYS1836
Nobel Prize 2010: Andre Geim & Konstantin Novoselov
E. Gerstner (2010)
10.1016/j.ijbiomac.2010.03.015
Biocomposites containing natural polymers and hydroxyapatite for bone tissue engineering.
M. Swetha (2010)
10.1016/S1369-7021(10)70002-X
Toxicity of single-walled carbon nanotube: How we were wrong?
H. Ren (2010)
10.1016/J.MSEB.2009.12.044
Strong adhesion of Saos-2 cells to multi-walled carbon nanotubes
M. Matsuoka (2010)
10.1016/J.CARBON.2010.07.045
Graphene substrates promote adherence of human osteoblasts and mesenchymal stromal cells
M. Kalbáčová (2010)
10.1016/J.MSEC.2010.05.007
Electrophoretic deposition of carbon nanotubeshydroxyapatite nanocomposites on titanium substrate
Yu Bai (2010)
10.1021/JP911539R
Photoluminescent Carbon Dots as Biocompatible Nanoprobes for Targeting Cancer Cells in Vitro
Qin Li (2010)
10.1021/MA902862U
Enhanced Mechanical Properties of Graphene-Based Poly(vinyl alcohol) Composites
X. Zhao (2010)
10.1073/pnas.0903269107
Geometric cues for directing the differentiation of mesenchymal stem cells
K. Kilian (2010)
A. Gloria (2010)
S. Sajadi (2010)
A. Geim (2010)
10.1016/J.MSEC.2010.10.014
Fabrication and mechanical properties of calcium phosphate cements (CPC) for bone substitution
Jingtao Zhang (2011)
10.1021/nn200500h
Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem cells.
T. R. Nayak (2011)
10.1002/jbm.a.32958
Bone formation on carbon nanotube composite.
M. Bhattacharya (2011)
10.1155/2011/290602
POLYMERIC SCAFFOLDS IN TISSUE ENGINEERING APPLICATION: A REVIEW
Brahatheeswaran Dhandayuthapani (2011)
10.1016/j.biomaterials.2010.08.090
Fluorescent PLLA-nanodiamond composites for bone tissue engineering.
Qingwei Zhang (2011)
10.1002/jbm.a.32952
Wear behavior and in vitro cytotoxicity of wear debris generated from hydroxyapatite-carbon nanotube composite coating.
D. Lahiri (2011)
10.1016/j.actbio.2011.03.019
Nanoscale hydroxyapatite particles for bone tissue engineering.
Hongjian Zhou (2011)
10.1016/S1369-7021(11)70145-6
Carbon nanotubes : from bench chemistry to promising biomedical applications
G. Pastorin (2011)
10.1016/J.MSEC.2011.04.022
Bioactive glass scaffolds for bone tissue engineering: state of the art and future perspectives.
Q. Fu (2011)
10.1258/ebm.2011.011132
Carbon dots of different composition and surface functionalization: cytotoxicity issues relevant to fluorescence cell imaging
Yanli Wang (2011)
10.1021/nn202190c
Origin of enhanced stem cell growth and differentiation on graphene and graphene oxide.
Wong Cheng Lee (2011)
S. Brady (2011)
10.1016/J.CARBON.2011.08.011
Surface modifications for the effective dispersion of carbon nanotubes in solvents and polymers
Sang Won Kim (2012)
10.1615/CRITREVBIOMEDENG.V40.I5.10
Bone tissue engineering: recent advances and challenges.
A. Amini (2012)
10.1016/j.tibtech.2012.07.005
Recent advances in bone tissue engineering scaffolds.
S. Bose (2012)
Basic neurochemistry : principles of molecular, cellular and medical neurobiology
S. Brady (2012)
10.1021/JP2102226
Simultaneous Reduction and Surface Functionalization of Graphene Oxide for Hydroxyapatite Mineralization
Hongyan Liu (2012)
10.1021/ac202667x
Fractionation of carbon-based nanomaterials by anion-exchange HPLC.
J. Vinci (2012)
10.1016/j.biomaterials.2012.03.063
Mechanical properties and biomineralization of multifunctional nanodiamond-PLLA composites for bone tissue engineering.
Qingwei Zhang (2012)
10.12693/APHYSPOLA.121.518
Nanocomposite Polymer Scaffolds for Bone Tissue Regeneration
E. Stodolak-Zych (2012)
10.1002/smll.201101706
In vivo NIR fluorescence imaging, biodistribution, and toxicology of photoluminescent carbon dots produced from carbon nanotubes and graphite.
Huiquan Tao (2012)
P. BankoffA.D. (2012)
10.1039/c3nr00803g
Three-dimensional graphene foams promote osteogenic differentiation of human mesenchymal stem cells.
S. W. Crowder (2013)
10.1016/J.MATTOD.2013.11.017
Bone tissue engineering using 3D printing
S. Bose (2013)
10.1016/J.CARBON.2013.06.029
Performance of carbon nanotube wires in extreme conditions
D. Janas (2013)
10.1016/j.actbio.2013.06.014
Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior.
S. Samavedi (2013)
10.1039/C3TB00018D
Carbon "quantum" dots for optical bioimaging.
P. Luo (2013)
10.1002/jcb.24451
TGF‐β/BMP signaling pathway is involved in cerium‐promoted osteogenic differentiation of mesenchymal stem cells
Dandan Liu (2013)
10.1039/C3RA00166K
Bioactive ceramics: from bone grafts to tissue engineering
A. J. Salinas (2013)
10.1039/C3TB20761G
Carbon dots functionalized gold nanorod mediated delivery of doxorubicin: tri-functional nano-worms for drug delivery, photothermal therapy and bioimaging.
S. Pandey (2013)
10.1021/nn402043c
In vivo biodistribution and toxicology of carboxylated graphene quantum dots.
M. Nurunnabi (2013)
10.1016/J.PROENG.2013.05.093
Bio-inspired Ceramics: Promising Scaffolds for Bone Tissue Engineering☆
M. López-Álvarez (2013)
10.5772/46192
Regenerative Medicine and Tissue Engineering
J. Andrades (2013)
10.1021/jz301911y
Hidden Properties of Carbon Dots Revealed After HPLC Fractionation.
J. Vinci (2013)
10.1002/APP.37924
Fabrication and characterization of poly(vinyl alcohol)/graphene oxide nanofibrous biocomposite scaffolds
Yuanyuan Qi (2013)
10.1021/ar300128j
Photoluminescence properties of graphene versus other carbon nanomaterials.
L. Cao (2013)
10.1002/ADFM.201203637
Self-Supporting Graphene Hydrogel Film as an Experimental Platform to Evaluate the Potential of Graphene for Bone Regeneration
Jiayu Lu (2013)
10.1007/s00441-013-1770-z
Bone tissue engineering by using a combination of polymer/Bioglass composites with human adipose-derived stem cells
W. Lu (2013)
10.3390/ijms14059182
Growth and Potential Damage of Human Bone-Derived Cells on Fresh and Aged Fullerene C60 Films
I. Kopová (2013)
10.1039/c3an01239e
In vitro detection of calcium in bone by modified carbon dots.
A. Krishna (2013)
10.1002/adhm.201200307
Carbon-based nanomaterials for tissue engineering.
Sook Hee Ku (2013)
10.1002/smll.201300571
Delivery of a therapeutic protein for bone regeneration from a substrate coated with graphene oxide.
Wan-Geun La (2013)
K. Mediaswanti (2013)
10.1166/JBN.2014.1969
Applications of carbon nanomaterials in bone tissue engineering.
J. Venkatesan (2014)
10.1002/ADFM.201400793
Dual Roles of Graphene Oxide in Chondrogenic Differentiation of Adult Stem Cells: Cell-Adhesion Substrate and Growth Factor-Delivery Carrier
H. Yoon (2014)
10.1038/srep04712
Enhancement mechanisms of graphene in nano-58S bioactive glass scaffold: mechanical and biological performance
C. Gao (2014)
10.1021/am4057826
Biomimetic and cell-mediated mineralization of hydroxyapatite by carrageenan functionalized graphene oxide.
Hongyan Liu (2014)
10.1002/anie.201403794
Three-dimensional scaffolds of carbonized polyacrylonitrile for bone tissue regeneration.
Seungmi Ryu (2014)
10.1016/J.NANTOD.2014.09.004
Carbon dots—Emerging light emitters for bioimaging, cancer therapy and optoelectronics
K. Holá (2014)
10.1039/c3nr06590a
Quantitative and real-time effects of carbon quantum dots on single living HeLa cell membrane permeability.
Weiqian Kong (2014)
10.1002/jbm.a.34993
The effect of graphene substrate on osteoblast cell adhesion and proliferation.
A. Aryaei (2014)
10.1007/s11426-014-5064-4
Biological applications of carbon dots
Wei Wang (2014)
10.1039/c4cc02442g
Synergistic acceleration in the osteogenesis of human mesenchymal stem cells by graphene oxide-calcium phosphate nanocomposites.
Rameshwar Tatavarty (2014)
10.7567/JJAP.53.06JD04
Graphene oxide coating facilitates the bioactivity of scaffold material for tissue engineering
E. Nishida (2014)
10.1039/c4nr00355a
Gelatin functionalized graphene oxide for mineralization of hydroxyapatite: biomimetic and in vitro evaluation.
Hongyan Liu (2014)
10.1039/C4TB00918E
Functionalized carbon dots enable simultaneous bone crack detection and drug deposition.
A. Krishna (2014)
10.1039/C4AY01052C
Separation of carbon quantum dots on a C18 column by binary gradient elution via HPLC
Lu Yan (2014)
10.1016/J.MSER.2014.04.001
Biomimetic porous scaffolds for bone tissue engineering
Shuilin Wu (2014)
10.1039/C4TC00988F
Carbon quantum dots: synthesis, properties and applications
Youfu Wang (2014)
U. LeeH. (2014)
L. WeiW. (2014)
10.1039/c4cs00269e
Carbon quantum dots and their applications.
Shi Ying Lim (2015)
10.1021/BK-2015-1215.CH003
Interactions between Graphene Oxide and Biomolecules from Surface Chemistry and Spectroscopy
Shanghao Li (2015)
10.1021/acsnano.5b05575
Self-Targeting Fluorescent Carbon Dots for Diagnosis of Brain Cancer Cells.
M. Zheng (2015)
10.1016/J.CARBON.2014.11.029
Covalent conjugation of mechanically stiff graphene oxide flakes to three-dimensional collagen scaffolds for osteogenic differentiation of human mesenchymal stem cells
Seokyung Kang (2015)
10.1016/J.CARBON.2015.04.048
Graphene-oxide-modified β-tricalcium phosphate bioceramics stimulate in vitro and in vivo osteogenesis
C. Wu (2015)
10.1088/1748-6041/10/1/015019
The promising application of graphene oxide as coating materials in orthopedic implants: preparation, characterization and cell behavior.
Changhong Zhao (2015)
10.1002/ADFM.201501524
Biocompatible PEG‐Chitosan@Carbon Dots Hybrid Nanogels for Two‐Photon Fluorescence Imaging, Near‐Infrared Light/pH Dual‐Responsive Drug Carrier, and Synergistic Therapy
Hui Wang (2015)
10.1021/acsami.5b00628
DNA-carbon dots function as fluorescent vehicles for drug delivery.
Han Ding (2015)
10.1088/0957-4484/26/16/161001
Graphene oxide nanoflakes incorporated gelatin-hydroxyapatite scaffolds enhance osteogenic differentiation of human mesenchymal stem cells.
M. Nair (2015)
10.1021/cr500304f
Broad family of carbon nanoallotropes: classification, chemistry, and applications of fullerenes, carbon dots, nanotubes, graphene, nanodiamonds, and combined superstructures.
V. Georgakilas (2015)
10.1166/JBN.2015.2115
Metallic Nanomaterials for Bone Tissue Engineering.
S. Dhivya (2015)
10.1016/J.APSUSC.2015.10.048
A new approach to fabrication of Cs/BG/CNT nanocomposite scaffold towards bone tissue engineering and evaluation of its properties
S. Shokri (2015)
10.1002/jat.3024
Graphene supports in vitro proliferation and osteogenic differentiation of goat adult mesenchymal stem cells: potential for bone tissue engineering
H. Elkhenany (2015)
10.1371/journal.pone.0123680
Growth and Potential Damage of Human Bone-Derived Cells Cultured on Fresh and Aged C60/Ti Films
I. Kopová (2015)
10.2147/IJN.S79971
Development of a new carbon nanotube–alginate–hydroxyapatite tricomponent composite scaffold for application in bone tissue engineering
R. Rajesh (2015)
10.1016/j.biomaterials.2015.04.027
In situ hybridization of carbon nanotubes with bacterial cellulose for three-dimensional hybrid bioscaffolds.
Subeom Park (2015)
10.1166/JNN.2015.9844
Bone Marrow Stem Cells Response to Collagen/Single-Wall Carbon Nanotubes-COOHs Nanocomposite Films with Transforming Growth Factor Beta 1.
Jianhua Wang (2015)
10.1038/srep18833
Enhanced Osteogenesis by Reduced Graphene Oxide/Hydroxyapatite Nanocomposites
Jong Ho Lee (2015)
10.1039/c5nr01107h
Graphene and hydroxyapatite self-assemble into homogeneous, free standing nanocomposite hydrogels for bone tissue engineering.
Xingyi Xie (2015)
10.3389/fbioe.2015.00202
Bioceramics and Scaffolds: A Winning Combination for Tissue Engineering
F. Baino (2015)
10.1021/CM504572B
Nontoxic Carbon Dots Potently Inhibit Human Insulin Fibrillation
Shanghao Li (2015)
10.1021/acsami.5b04811
Vortex-aligned fullerene nanowhiskers as a scaffold for orienting cell growth.
Venkatachalam Krishnan (2015)
10.3390/ma8125481
Graphene-Based Materials for Stem Cell Applications
Tae-Hyung Kim (2015)
10.1039/c4nr05060f
Strontium eluting graphene hybrid nanoparticles augment osteogenesis in a 3D tissue scaffold.
S. Kumar (2015)
10.1038/boneres.2015.5
TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation
M. S. Rahman (2015)
10.1002/anie.201501193
Red, green, and blue luminescence by carbon dots: full-color emission tuning and multicolor cellular imaging.
Kai Jiang (2015)
10.1016/J.CARBON.2014.12.045
Recent advances in bioapplications of C-dots
Andong Zhao (2015)
10.1007/s12274-014-0644-3
The photoluminescence mechanism in carbon dots (graphene quantum dots, carbon nanodots, and polymer dots): current state and future perspective
Shoujun Zhu (2015)
10.1039/C5TB00570A
Rapid microwave-assisted synthesis of ultra-bright fluorescent carbon dots for live cell staining, cell-specific targeting and in vivo imaging.
Hua He (2015)
10.1002/adma.201500323
Red-Emissive Carbon Dots for Fluorescent, Photoacoustic, and Thermal Theranostics in Living Mice.
Jiechao Ge (2015)
10.1177/0883911515569918
MC3T3-E1 preosteoblast cell-mediated mineralization of hydroxyapatite by poly-dopamine-functionalized graphene oxide
Ju Cheng (2015)
10.1039/c5nr01580d
Reduced graphene oxide-coated hydroxyapatite composites stimulate spontaneous osteogenic differentiation of human mesenchymal stem cells.
Jong Ho Lee (2015)
10.1039/C5RA21137A
Carbon dots isolated from chromatographic fractions for sensing applications
Lizhen Liu (2015)
10.1002/jbm.a.35283
Enhanced osteogenic differentiation of mesenchymal stem cells on poly(L-lactide) nanofibrous scaffolds containing carbon nanomaterials.
Shun Duan (2015)
10.1021/acsami.5b00862
Enhanced proliferation and osteogenic differentiation of mesenchymal stem cells on graphene oxide-incorporated electrospun poly(lactic-co-glycolic acid) nanofibrous mats.
Yu Luo (2015)
10.1039/C5AY01978H
Fluorescent carbon dots from beer for breast cancer cell imaging and drug delivery
Ziyi Wang (2015)
10.1016/J.COMPSCITECH.2015.08.010
High performance luminescent thermosetting waterborne hyperbranched polyurethane/carbon quantum dot nanocomposite with in vitro cytocompatibility
S. Gogoi (2015)
10.1177/0960327114550883
Carbon nanotube-reinforced hydroxyapatite composite and their interaction with human osteoblast in vitro
P. Khalid (2015)
R. Rajesh (2015)
10.1016/j.addr.2016.03.007
Graphene-based materials for tissue engineering.
S. Shin (2016)
10.1002/adma.201505375
Multilayered Graphene Hydrogel Membranes for Guided Bone Regeneration.
Jiayu Lu (2016)
10.1007/S40898-016-0001-2
Metals for bone implants: safety, design, and efficacy
N. Shayesteh Moghaddam (2016)
10.1021/ACSAMI.6B12252
Aspirin-Based Carbon Dots, a Good Biocompatibility of Material Applied for Bioimaging and Anti-Inflammation.
Xiaowei Xu (2016)
10.1021/acsami.6b05635
Poly(propylene fumarate)/Polyethylene Glycol-Modified Graphene Oxide Nanocomposites for Tissue Engineering.
A. Díez-Pascual (2016)
10.1039/C6RA08006E
Tailoring in vitro biological and mechanical properties of polyvinyl alcohol reinforced with threshold carbon nanotube concentration for improved cellular response
Tejinder Kaur (2016)
10.1039/C6TB00390G
3D-printed bioceramic scaffolds with a Fe3O4/graphene oxide nanocomposite interface for hyperthermia therapy of bone tumor cells.
Yongliang Zhang (2016)
10.1007/s41779-016-0016-4
Development of carboxylated multi-walled carbon nanotubes and bovine serum albumin reinforced hydroxyapatite for bone substitute applications
F. Gholami (2016)
10.2147/IJN.S115468
Graphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway
Xinxin Yan (2016)
10.1016/J.CARBON.2016.01.086
Fabrication and properties of carbon nanotube-reinforced hydroxyapatite composites by a double in situ synthesis process
Hai-peng Li (2016)
10.1039/C6TB02241C
"Dark" carbon dots specifically "light-up" calcified zebrafish bones.
Shanghao Li (2016)
10.1039/C6TB01259K
Carbon dots as a trackable drug delivery carrier for localized cancer therapy in vivo.
Q. Zeng (2016)
10.1039/C6RA16709H
Development of functionalized multi-walled carbon nanotube-based polysaccharide–hydroxyapatite scaffolds for bone tissue engineering
R. Rajesh (2016)
10.1016/j.colsurfb.2016.05.007
Crossing the blood-brain-barrier with transferrin conjugated carbon dots: A zebrafish model study.
Shanghao Li (2016)
10.1016/j.dental.2015.09.008
Design and characterization of calcium phosphate ceramic scaffolds for bone tissue engineering.
I. Denry (2016)
10.1016/j.msec.2016.01.078
Enhanced bone formation in electrospun poly(L-lactic-co-glycolic acid)-tussah silk fibroin ultrafine nanofiber scaffolds incorporated with graphene oxide.
Weili Shao (2016)
10.1039/C6TA04813G
Improving the functionality of carbon nanodots: doping and surface functionalization
Youngjin Park (2016)
10.2174/1385272819666150730220948
Carbon Quantum Dots: Surface Passivation and Functionalization
K. Dimos (2016)
10.1039/c5cc07754k
Semiconductor and carbon-based fluorescent nanodots: the need for consistency.
A. Cayuela (2016)
10.2147/IJN.S104778
Graphene oxide scaffold accelerates cellular proliferative response and alveolar bone healing of tooth extraction socket
E. Nishida (2016)
10.1016/J.NANTOD.2016.08.006
Shining carbon dots: Synthesis and biomedical and optoelectronic applications
Fanglong Yuan (2016)
10.1021/acsami.6b07453
One-Pot To Synthesize Multifunctional Carbon Dots for Near Infrared Fluorescence Imaging and Photothermal Cancer Therapy.
M. Zheng (2016)
10.1039/C6NR05055G
Transferrin conjugated nontoxic carbon dots for doxorubicin delivery to target pediatric brain tumor cells.
Shanghao Li (2016)
10.1002/adhm.201600359
Self-Assembled Heterojunction Carbon Nanotubes Synergizing with Photoimmobilized IGF-1 Inhibit Cellular Senescence.
Wu-Ya Chen (2016)
10.2147/IJN.S110920
A nano-sandwich construct built with graphene nanosheets and carbon nanotubes enhances mechanical properties of hydroxyapatite–polyetheretherketone scaffolds
P. Feng (2016)
10.1016/j.lfs.2016.08.003
A novel 3D bone-mimetic scaffold composed of collagen/MTA/MWCNT modulates cell migration and osteogenesis.
T. Valverde (2016)
10.3390/polym8080287
Novel Electrospun Polylactic Acid Nanocomposite Fiber Mats with Hybrid Graphene Oxide and Nanohydroxyapatite Reinforcements Having Enhanced Biocompatibility
Chen Liu (2016)
10.1039/C6RA15267H
Room-temperature fabrication of a three-dimensional reduced-graphene oxide/polypyrrole/hydroxyapatite composite scaffold for bone tissue engineering
Fuxiang Song (2016)
10.1039/C6TB02131J
Heteroatom-doped carbon dots: synthesis, characterization, properties, photoluminescence mechanism and biological applications.
Quan Xu (2016)
10.1039/C6RA02341J
A renewable resource based carbon dot decorated hydroxyapatite nanohybrid and its fabrication with waterborne hyperbranched polyurethane for bone tissue engineering
S. Gogoi (2016)
10.1016/j.aca.2016.08.014
Determination of the composition, encapsulation efficiency and loading capacity in protein drug delivery systems using circular dichroism spectroscopy.
Zhili Peng (2016)
10.1002/cbic.201500694
Imaging Cancer Cells Expressing the Folate Receptor with Carbon Dots Produced from Folic Acid
Susanta Kumar Bhunia (2016)
10.1039/c5nr06906h
Engineering a multi-biofunctional composite using poly(ethylenimine) decorated graphene oxide for bone tissue regeneration.
S. Kumar (2016)
10.5650/jos.ess15248
Interactions between Carbon Nanomaterials and Biomolecules.
Xu Han (2016)
10.1039/c6nr00247a
Doxorubicin conjugated functionalizable carbon dots for nucleus targeted delivery and enhanced therapeutic efficacy.
Lei Yang (2016)
10.1039/C6TB00976J
Carbon dots: surface engineering and applications.
Weijian Liu (2016)
10.1002/adhm.201500770
Effects of Graphene Quantum Dots on the Self-Renewal and Differentiation of Mesenchymal Stem Cells.
Jichuan Qiu (2016)
10.1021/acsami.5b09232
Biomimetic Mineralized Hierarchical Graphene Oxide/Chitosan Scaffolds with Adsorbability for Immobilization of Nanoparticles for Biomedical Applications.
Chaoming Xie (2016)
10.1016/j.msec.2015.10.075
Influence of low contents of superhydrophilic MWCNT on the properties and cell viability of electrospun poly (butylene adipate-co-terephthalate) fibers.
B. V. Rodrigues (2016)
10.1038/srep19343
Bioactivity of periodontal ligament stem cells on sodium titanate coated with graphene oxide
Qi Zhou (2016)
10.2174/1874325001610010877
Carbon Nanostructures in Bone Tissue Engineering
B. Perkins (2016)
G. MotaR.C.d.A. (2016)
E. Nishida (2016)
10.1089/ten.tea.2017.0430
Strategic Directions in Osteoinduction and Biomimetics
HabibovicPamela (2017)
10.1021/acsami.7b04668
Fluorescent Nanoparticles with Tissue-Dependent Affinity for Live Zebrafish Imaging.
D. K. Khajuria (2017)
10.1016/J.JIEC.2016.10.029
A unique scaffold for bone tissue engineering: An osteogenic combination of graphene oxide–hyaluronic acid–chitosan with simvastatin
A. R. Unnithan (2017)
10.1186/s40580-017-0096-z
Guiding osteogenesis of mesenchymal stem cells using carbon-based nanomaterials
Ee-Seul Kang (2017)
10.1007/s41061-017-0102-2
Advances in Production and Applications of Carbon Nanotubes
Xilai Jia (2017)
10.1016/J.CCR.2017.06.001
Carbon dots: Biomacromolecule interaction, bioimaging and nanomedicine
Zhili Peng (2017)
10.1002/jbm.a.35684
Multi and mixed 3D-printing of graphene-hydroxyapatite hybrid materials for complex tissue engineering.
A. Jakus (2017)
10.1097/BOT.0000000000000978
Size Matters: Defining Critical in Bone Defect Size!
E. Schemitsch (2017)
10.3390/polym9020067
Polymers in Carbon Dots: A Review
Yiqun Zhou (2017)
10.1039/c7nr05731h
Carbon dots: promising biomaterials for bone-specific imaging and drug delivery.
Zhili Peng (2017)
10.1039/C6TA10220D
Recent progress in carbon dot–metal based nanohybrids for photochemical and electrochemical applications
B. De (2017)
10.1002/mabi.201600271
Nano-Bio Engineered Carbon Dot-Peptide Functionalized Water Dispersible Hyperbranched Polyurethane for Bone Tissue Regeneration.
S. Gogoi (2017)
10.1039/c7bm00358g
Carbon dots for tracking and promoting the osteogenic differentiation of mesenchymal stem cells.
Dan Shao (2017)
10.1002/9781119441632.CH96
Synthetic Biodegradable Polymers for Bone Tissue Engineering
Jiuhong Zhang (2017)
10.1016/j.msec.2017.03.269
Graphene oxide versus graphene for optimisation of PMMA bone cement for orthopaedic applications.
E. Paz (2017)
10.1016/J.CARBON.2017.02.013
Three-dimensional porous scaffold by self-assembly of reduced graphene oxide and nano-hydroxyapatite composites for bone tissue engineering
W. Nie (2017)
10.1039/c7nr04352j
Biocompatible and blood-brain barrier permeable carbon dots for inhibition of Aβ fibrillation and toxicity, and BACE1 activity.
Xu Han (2017)
10.1038/srep46604
Graphene oxide as an interface phase between polyetheretherketone and hydroxyapatite for tissue engineering scaffolds
S. Peng (2017)
10.1038/boneres.2017.59
Bone biomaterials and interactions with stem cells
C. Gao (2017)
10.1021/acsami.7b14267
Electrospun Poly(3-hydroxybutyrate-co-4-hydroxybutyrate)/Graphene Oxide Scaffold: Enhanced Properties and Promoted in Vivo Bone Repair in Rats.
T. Zhou (2017)
10.1021/acsomega.7b01139
Development of Graphene Oxide-/Galactitol Polyester-Based Biodegradable Composites for Biomedical Applications
Janeni Natarajan (2017)
10.1016/j.msec.2017.05.017
Scaffolds for Bone Tissue Engineering: State of the art and new perspectives.
L. Roseti (2017)
10.1002/9783527689934.CH16
Bone Tissue Engineering: State of the Art, Challenges, and Prospects
J. Gordeladze (2017)
10.1016/j.msec.2016.08.063
On the biological performance of graphene oxide-modified chitosan/polyvinyl pyrrolidone nanocomposite membranes: In vitro and in vivo effects of graphene oxide.
Nafiseh Mahmoudi (2017)
E. Hirata (2017)
Handbook of composites from renewable materials
Vijay Kumar Thakur (2017)
C. DuttaR. (2017)
10.1039/c8nr02177e
Graphitic and oxidised high pressure high temperature (HPHT) nanodiamonds induce differential biological responses in breast cancer cell lines† †Electronic supplementary information (ESI) available: Supplementary methods and figures. See DOI: 10.1039/C8NR02177E
Ben J. Woodhams (2018)
10.3390/ijms19030826
Applications of Metals for Bone Regeneration
K. Glenske (2018)
10.1016/j.jmbbm.2018.03.016
In-vitro biocompatibility, bioactivity, and mechanical strength of PMMA-PCL polymer containing fluorapatite and graphene oxide bone cements.
F. Pahlevanzadeh (2018)
10.1002/adhm.201701061
Current Approaches to Bone Tissue Engineering: The Interface between Biology and Engineering
Jiao Jiao Li (2018)
10.1021/acsami.8b02792
Accelerated Bone Regeneration by Nitrogen-Doped Carbon Dots Functionalized with Hydroxyapatite Nanoparticles.
D. K. Khajuria (2018)
10.1093/rb/rby013
Bone tissue engineering via growth factor delivery: from scaffolds to complex matrices
Tinke-Marie De Witte (2018)
10.1016/j.bioactmat.2017.08.004
The development of collagen based composite scaffolds for bone regeneration
D. Zhang (2018)
10.1186/s12989-018-0253-5
Carbon black suppresses the osteogenesis of mesenchymal stem cells: the role of mitochondria
Yulai Shen (2018)
10.1021/acs.bioconjchem.8b00400
Zero-Dimensional Carbon Dots Enhance Bone Regeneration, Osteosarcoma Ablation, and Clinical Bacterial Eradication.
Yao Lu (2018)
10.3390/ma11020295
Carbon-Based Nanomaterials/Allotropes: A Glimpse of Their Synthesis, Properties and Some Applications
Salisu Nasir (2018)
10.1080/10667857.2017.1404278
Fabrication of magnesium-based metallic scaffolds for bone tissue engineering
Lipi Malladi (2018)
10.2147/DDDT.S165440
Current development of biodegradable polymeric materials for biomedical applications
Richard Song (2018)
10.1007/s10856-018-6095-8
Achieving stem cell imaging and osteogenic differentiation by using nitrogen doped graphene quantum dots
Hao Geng (2018)
10.1016/j.carbpol.2017.11.091
One pot synthesis of carbon dots decorated carboxymethyl cellulose- hydroxyapatite nanocomposite for drug delivery, tissue engineering and Fe3+ ion sensing.
C. Sarkar (2018)
10.1093/rb/rby001
Effect of microporosity on scaffolds for bone tissue engineering
Ke Zhang (2018)
10.1126/scitranslmed.aam8828
Mechanobiologically optimized 3D titanium-mesh scaffolds enhance bone regeneration in critical segmental defects in sheep
A. Pobloth (2018)
10.1016/J.MATPR.2018.04.160
Synergistic combination of bioactive glasses and polymers for enhanced bone tissue regeneration
S. Kargozar (2018)
10.1016/J.MATLET.2018.08.108
Aligned porous chitosan/graphene oxide scaffold for bone tissue engineering
Yaxin Liu (2018)
10.1016/J.CCLET.2018.04.018
Toxicity and bio-distribution of carbon dots after single inhalation exposure in vivo
Yue Yang (2018)
10.1021/acsami.8b03727
Fluorescence Detection of Bone Microcracks Using Monophosphonated Carbon Dots.
Fatemeh Ostadhossein (2018)
10.3390/molecules23020378
Cancer Targeting and Drug Delivery Using Carbon-Based Quantum Dots and Nanotubes
J. Pardo (2018)
10.1016/j.ijbiomac.2017.11.033
Preparation and characterization of three-dimensional scaffolds based on hydroxypropyl chitosan-graft-graphene oxide.
P. Sivashankari (2018)
10.1201/9781315121079-3
Bioactive Ceramics and Metals for Regenerative Engineering
Changchun Zhou (2018)
10.1038/s41598-018-25330-x
Photoluminescent Cationic Carbon Dots as efficient Non-Viral Delivery of Plasmid SOX9 and Chondrogenesis of Fibroblasts
X. Cao (2018)
10.1186/s11671-018-2432-6
Graphene Oxide Hybridized nHAC/PLGA Scaffolds Facilitate the Proliferation of MC3T3-E1 Cells
C. Liang (2018)
H. Miyaji (2018)
10.1021/ACSABM.8B00599
Three-Dimensionally N-Doped Graphene–Hydroxyapatite/Agarose as an Osteoinductive Scaffold for Enhancing Bone Regeneration
Jianjun Luo (2019)
10.1186/s12989-019-0299-z
Cellular Toxicity and Immunological Effects of Carbon-based Nanomaterials
Xia Yuan (2019)
10.1002/ADEM.201900287
Bioactıve Glass‐Polymer Nanocomposites for Bone Tıssue Regeneration Applicatıons: A Revıew
Melek Erol‐Taygun (2019)
10.1111/jipb.12887
Acknowledgements.
(2019)
10.1016/j.colsurfb.2019.03.035
Bioactive carbon dots direct the osteogenic differentiation of human bone marrow mesenchymal stem cells.
Yu Han (2019)
10.1016/j.msec.2019.03.003
Egg shell-derived calcium phosphate/carbon dot nanofibrous scaffolds for bone tissue engineering: Fabrication and characterization.
S. Shafiei (2019)
10.1002/PPSC.201800315
Facile Synthesis of Mg2+-Doped Carbon Dots as Novel Biomaterial Inducing Cell Osteoblastic Differentiation
M. Yang (2019)
10.3390/molecules24091669
Fabrication and Application of Novel Porous Scaffold in Situ-Loaded Graphene Oxide and Osteogenic Peptide by Cryogenic 3D Printing for Repairing Critical-Sized Bone Defect
Yidi Zhang (2019)
10.1039/C8RA09729A
Bone-targeting carbon dots: effect of nitrogen-doping on binding affinity
Kyung Kwan Lee (2019)
10.1080/21691401.2019.1576706
Effects of graphene oxide and graphene oxide quantum dots on the osteogenic differentiation of stem cells from human exfoliated deciduous teeth
X. Yang (2019)
10.1002/sctm.18-0289
Bioconjugated Carbon Dots for Delivery of siTnfα to Enhance Chondrogenesis of Mesenchymal Stem Cells by Suppression of Inflammation
Jianwei Liu (2019)
10.1016/J.APCATB.2019.02.019
Size-Dependent Photocatalytic Activity of Carbon Dots with Surface-State Determined Photoluminescence.
Yiqun Zhou (2019)
10.1021/ACSOMEGA.8B01763
Doping of Carbon Quantum Dots (CDs) in Calcium Phosphate Nanorods for Inducing Ectopic Chondrogenesis via Activation of the HIF-α/SOX-9 Pathway
Bodhisatwa Das (2019)
10.1016/j.tiv.2019.02.015
Doping of carbon nanodots for saving cells from silver nanotoxicity: A study on recovering osteogenic differentiation potential.
Bodhisatwa Das (2019)
10.3389/fbioe.2019.00004
Biological Response to Carbon-Family Nanomaterials: Interactions at the Nano-Bio Interface
M. Rahmati (2019)
R. Eivazzadeh‐Keihan (2019)



This paper is referenced by
10.2147/IJN.S311001
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Lijia Cheng (2021)
10.3390/APP11156814
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Maria Cristina Cringoli (2021)
10.1039/D1RA01849C
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Xinmin Zheng (2021)
10.1016/J.MSEC.2020.111584
A bioinspired, ice-templated multifunctional 3D cryogel composite crosslinked through in situ reduction of GO displayed improved mechanical, osteogenic and antimicrobial properties.
Vianni Chopra (2021)
10.3390/COATINGS11020232
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B. Vercelli (2021)
10.3390/biomedicines9050570
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Simone Adorinni (2021)
10.3390/nano11051083
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Pariya Zare (2021)
10.1016/j.matlet.2020.128990
Ultrasonic-assisted preparation of reduced graphene oxide-hydroxyapatite nanocomposite for bone remodeling
B. Li (2021)
10.3390/molecules26134084
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Petr Rozhin (2021)
10.1016/j.colsurfb.2021.111785
Composites made of polyorganophosphazene and carbon nanotube up-regulating osteogenic activity of BMSCs under electrical stimulation.
Yiqian Huang (2021)
10.3390/biomedicines9091138
Rapid Fabrication of MgNH4PO4·H2O/SrHPO4 Porous Composite Scaffolds with Improved Radiopacity via 3D Printing Process
Xiaofeng Cao (2021)
10.1007/s00339-021-04708-1
Influence of carbon nanotubes reinforcement on the structural feature and bioactivity of SiO2–Al2O3–MgO–K2CO3–CaO–MgF2 bioglass
Shweta (2021)
10.1007/978-1-0716-1246-0_17
Biomimetic 3D-Bone Tissue Model.
Mahmut Parmaksiz (2021)
10.1016/J.MATDES.2021.109941
Enhanced three-dimensional printing scaffold for osteogenesis using a mussel-inspired graphene oxide coating
Ji Min Seok (2021)
10.1016/j.neuint.2021.105005
Graphene-based hybrid materials as promising scaffolds for peripheral nerve regeneration
S. Grijalvo (2021)
10.1039/d0tb01601b
Mimicking the electrophysiological microenvironment of bone tissue using electroactive materials to promote its regeneration.
Tianyi Zheng (2020)
10.3390/nano10081560
Facile Synthesis of “Boron-Doped” Carbon Dots and Their Application in Visible-Light-Driven Photocatalytic Degradation of Organic Dyes
Zhili Peng (2020)
10.1080/02678292.2020.1783705
Self-assembly and ion transport behaviour of liquid-crystalline graphene oxide multilayer sandwich nanopapers
Lele Bie (2020)
10.1021/acssensors.0c01556
Recent Developments of Carbon Dots in Biosensing: A Review.
Chunyu Ji (2020)
10.3389/fmats.2020.594686
Tailoring Scaffolds for Orthopedic Application With Anti-Microbial Properties: Current Scenario and Future Prospects
A. Preethi (2020)
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