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Effect Of Chewing Betel Nut (Areca Catechu) On Salivary Cortisol Measurement.

Martina Konečná, Samuel S. Urlacher
Published 2015 · Medicine
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OBJECTIVES Cultural practices may compromise the accuracy of salivary hormone measurements and must be considered when designing human biology research protocols. This study aims to evaluate the acute effect of one common human practice-chewing betel nut-on the measurement of salivary cortisol levels under field conditions. MATERIALS AND METHODS Data were collected from 17 adult habitual betel nut users (males = 11; females = 6; mean age = 32.8 years) from a small rural community in Papua New Guinea. Saliva was collected in time series from each participant before and at 0, 15, 30, 45, 60, and 75 min after chewing betel nut. Samples were analyzed by radioimmunoassay and cortisol levels were compared across time using linear mixed effects modeling. RESULTS Measured mean cortisol concentration fell nearly 40% immediately following betel nut use and remained significantly below baseline levels for the following 45 min (all P < 0.05). Cortisol concentrations measured at 60 min and 75 min were indistinguishable from baseline levels (all P > 0.16). DISCUSSION Chewing betel nut is associated with a transient but significant reduction in measured levels of salivary cortisol. Future research must take this into account in populations where betel nut use is prevalent.
This paper references
10.1002/bimj.200810425
Simultaneous inference in general parametric models.
Torsten Hothorn (2008)
10.1002/ajhb.10203
Salivary testosterone and body composition among Ariaal males.
Benjamin Charles Campbell (2003)
10.1080/13556210120091482
The oral health consequences of chewing areca nut.
Chetan R. Trivedy (2002)
10.1002/ajpa.1330920410
Brief communication: effect of coca-leaf chewing on salivary progesterone assays.
Virginia J Vitzthum (1993)
10.1080/13556210020091437
Global epidemiology of areca nut usage.
Prakash C Gupta (2002)
10.1007/s10565-011-9195-5
Betel nut extract and arecoline block insulin signaling and lipid storage in 3T3-L1 adipocytes
Tusty-Jiuan Hsieh (2011)
10.1002/ajpa.20513
Effect of chewing betel nut on measurements of salivary progesterone and estradiol.
Alejandra Núñez-de la Mora (2007)
10.1016/j.drugalcdep.2009.06.021
Betel nut chewing during pregnancy, Madang province, Papua New Guinea.
M. Thurman Senn (2009)
10.1080/13556210120091446
Anthropological perspectives on use of the areca nut.
Simon S. Strickland (2002)
10.1002/ajhb.1310010304
Development of protocols for the application of salivary steroid analysis to field conditions.
Susan F. Lipson (1989)
10.1016/0022-4731(87)90297-4
The measurement of hormones in saliva: possibilities and pitfalls.
R. F. W. Vining (1987)
10.1002/ajpa.1330310507
Human salivary steroids: Methodological considerations and applications in physical anthropology
Peter T Ellison (1988)
10.1159/000054038
Effects of Betel Chewing on the Central and Autonomic Nervous Systems
N S Chu (2001)
nlme : linear and nonlinear mixed effects models
J Pinheiro (2015)



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