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Nickel-Catalyzed Arylboration Of Alkenylarenes: Synthesis Of Boron-Substituted Quaternary Carbons And Regiodivergent Reactions.

Liang-An Chen, Alan R. Lear, Pin Gao, Michael K. Brown
Published 2019 · Chemistry, Medicine
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A method for the construction of boron-substituted quaternary carbons or diarylquaternary carbons by arylboration of highly substituted alkenylarenes is presented. A wide range of alkenes and arylbromides can participate in this reaction thus allowing for a diverse assortment of products to be prepared. In addition, a solvent dependent regiodivergent arylboration of 1,2-disubstituted alkenylarenes is presented, thus greatly increasing the scope of products that can be accessed.
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