Meta‐analysis Of Risk Factors And Complications Associated With Atrial Fibrillation After Oesophagectomy
Dimitrios Schizas, Marinos Kosmopoulos, Stefanos Giannopoulos, Spyridon Giannopoulos, Damianos G. Kokkinidis, Nikoleta Karampetsou, Christos A. Papanastasiou, Ioannis Rouvelas, Theodore Liakakos
Published 2019 · Medicine
Download PDFAnalyze on Scholarcy
BACKGROUND Oesophagectomy is associated with high morbidity and mortality rates. New-onset atrial fibrillation (AF) is a frequent complication following oesophagectomy. Several studies have explored whether new-onset AF is associated with adverse events after oesophagectomy. METHODS This review was performed according to PRISMA guidelines. Eligible studies were identified through a search of PubMed, Scopus and Cochrane CENTRAL databases up to 25 November 2018. A meta-analysis was conducted with the use of random-effects modelling. The I2 statistic was used to assess for heterogeneity. RESULTS In total, 53 studies including 9087 patients were eligible for analysis. The overall incidence of postoperative AF was 16·5 per cent. Coronary artery disease and hypertension were associated with AF, whereas diabetes, smoking and chronic obstructive pulmonary disease were not. Patients with AF had a significantly higher risk of overall postoperative adverse events than those without fibrillation (odds ratio (OR) 5·50, 95 per cent c.i. 3·51 to 8·30), including 30-day mortality (OR 2·49, 1·70 to 3·64), anastomotic leak (OR 2·65, 1·53 to 4·59) and pneumonia (OR 3·42, 2·39 to 4·90). CONCLUSION Postoperative AF is frequently observed in patients undergoing oesophagectomy for cancer. It is associated with an increased risk of death and postoperative complications.
This paper references
Usage of "Reversal Penetrating Technique" with Ancillary Trocar in Minimally Invasive Ivor Lewis Esophagectomy.
Saibo Pan (2017)
Video-assisted thoracoscopic esophagectomy for esophageal squamous carcinoma
Wang Qun (2007)
The suppressive effects of landiolol administration on the occurrence of postoperative atrial fibrillation and tachycardia, and plasma IL-6 elevation in patients undergoing esophageal surgery: A randomized controlled clinical trial.
Yuta Horikoshi (2017)
Atrial fibrillation after esophagectomy: an indicator of postoperative morbidity
Stanislaw Peter Stawicki (2011)
Benchmarking Complications Associated with Esophagectomy
Donald E Low (2019)
Benchmark values for transthoracic esophagectomy are not set as the defined "best possible"-a validation study.
Olli Helminen (2018)
The postoperative complication for adenocarcinoma of esophagogastric junction.
Hui Zhang (2015)
Preoperative Echocardiographic Indices of Diastolic Dysfunction and Brain Natriuretic Peptide in Predicting Postoperative Atrial Fibrillation After Noncardiac Surgery
Oren Brecher (2017)
Association between Postoperatively Developed Atrial Fibrillation and Long-Term Mortality after Esophagectomy in Esophageal Cancer Patients: An Observational Study
Ji-Hyun Chin (2016)
Early experience with totally robotic esophagectomy for malignancy. Surgical and oncological outcomes
Francesco Guerra (2018)
Type 2 diabetes mellitus and risk of incident atrial fibrillation in women.
Tobias Schoen (2012)
Atrial fibrillation and coronary artery disease: Resembling twins?
Masaharu Akao (2014)
Routine endoscopy to detect anastomotic leakage after esophagectomy.
Richard D. Page (2013)
Comparison of thoracolaparoscopic esophagectomy with cervical anastomosis with McKeown esophagectomy for middle esophageal cancer
Hai-tao Huang (2015)
50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study
Renate B. Schnabel (2015)
The first postesophagectomy chest X-ray predicts respiratory failure and the need for tracheostomy.
Emmanuel Gabriel (2018)
The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P. T. Higgins (2011)
Minimally invasive esophagectomy: results of a prospective phase II multicenter trial-the eastern cooperative oncology group (E2202) study.
James D. Luketich (2015)
Guidelines for Diagnosis and Treatment of Carcinoma of the Esophagus April 2012 edited by the Japan Esophageal Society
Hiroyuki Kuwano (2014)
Esophageal Society. Esophagus
AS Borggreve (2018)
Risk of atrial fibrillation in diabetes mellitus: A nationwide cohort study
Jannik Langtved Pallisgaard (2016)
Increased N-terminal pro-brain natriuretic peptide level predicts atrial fibrillation after surgery for esophageal carcinoma.
Jiang-long Hou (2008)
Long-term survival and toxicity outcomes of intensity modulated radiation therapy for the treatment of esophageal cancer: A large single-institutional cohort study
An-hui Shi (2017)
Impact of atrial fibrillation on long‐term survival following oesophagectomy: a 21‐year observational study
Cameron I. Wells (2018)
Systematic classification of morbidity and mortality after thoracic surgery.
Andrew J. E. Seely (2010)
Preoperative left atrial dysfunction and risk of postoperative atrial fibrillation complicating thoracic surgery
Charles T. Klodell (2012)
Survival based radiographic-grouping for esophageal squamous cell carcinoma may impact clinical T stage
Wenjie Cai (2018)
Recent improvements in the management of esophageal anastomotic leak after surgery for cancer.
Mathieu Messager (2017)
Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Florian Lordick (2016)
Minimally invasive esophagectomy for Barrett's adenocarcinoma.
Emanuele Asti (2018)
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
David Moher (2009)
Atrial fibrillation: profile and burden of an evolving epidemic in the 21st century.
Jocasta Ball (2013)
Is thoracoscopic-laparoscopic esophagectomy a better alternative to thoracoscopic esophagectomy?
Fei Yao (2017)
Changes in blood pressure and heart rhythm during transhiatal esophagectomy.
Novin Nikbakhsh (2012)
Dose escalated neoadjuvant chemoradiotherapy with dose-painting intensity-modulated radiation therapy and improved pathologic complete response in locally advanced esophageal cancer.
Puja S. Venkat (2017)
The first series of completely robotic esophagectomies with three-field lymphadenectomy: initial experience
Kemp H. Kernstine (2008)
Comparison of perioperative outcomes between open and minimally invasive esophagectomy for esophageal cancer
Teng Mao (2015)
Minimally Invasive Esophagectomy is Safe and Effective Following Neoadjuvant Chemoradiation Therapy
Kfir Ben-David (2011)
A randomized, open label study of the efficacy of prophylactic 24-h low-dose landiolol for atrial fibrillation in transthoracic esophagectomy
Takahiro Yoshida (2016)
Comparison of different risk-adjustment models in assessing short-term surgical outcome after transthoracic esophagectomy in patients with esophageal cancer.
Dirk J Bosch (2011)
Abdominocervical (transhiatal) oesophagectomy in the management of oesophageal carcinoma.
David C. Gotley (1990)
Comparison of the short-term clinical outcome between open and minimally invasive esophagectomy by comprehensive complication index
Guo-yuan Ma (2018)
Long‐term outcomes of 530 esophageal squamous cell carcinoma patients with minimally invasive Ivor Lewis esophagectomy
Wang Qi (2018)
Atrial fibrillation after esophagectomy is a marker for postoperative morbidity and mortality.
S Chidamabara Murthy (2003)
Transthoracic esophagectomy: a safe approach to carcinoma of the esophagus.
Douglas J. Mathisen (1988)
Totally minimally invasive esophagectomy after neoadjuvant chemoradiotherapy: Long‐term oncologic outcomes
Merel Lubbers (2018)
Postoperative atrial fibrillation in noncardiothoracic surgical patients.
Kathleen K Christians (2001)
Initial experience from a large referral center with robotic-assisted Ivor Lewis esophagogastrectomy for oncologic purposes
Sebastían De La Fuente (2013)
A Single Intercostal Space Thoracoscopic Approach for Minimally Invasive Ivor Lewis Esophagectomy.
Early Experience of Robot-Assisted Esophagectomy With Circular End-to-End Stapled Anastomosis.
Jon O. Wee (2016)
Lancet 2016; 388: 1459–1544
Burden of Disease Study (2015)
The clinical significance of systemic inflammation score in esophageal squamous cell carcinoma
Lihui Han (2015)
Experience with minimally invasive esophagectomy
Georgia C. Collins (2005)
Atrial fibrillation after surgery for esophageal carcinoma: clinical and prognostic significance.
Jian-yang Ma (2006)
Atrial fibrillation after esophageal cancer surgery: an analysis of 207 consecutive patients
Toshiyasu Ojima (2013)
Role of inflammation in atrial fibrillation pathophysiology and management.
Masahide Harada (2015)
NF-kappaB-dependent transcriptional regulation of the cardiac scn5a sodium channel by angiotensin II.
Lijuan Shang (2008)
ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions
Jonathan A C Sterne (2016)
Incidence and types of arrhythmias after mediastinal manipulation during transhiatal esophagectomy.
Surender Kumar Malhotra (2006)
Minimally Invasive Esophagectomy in the Lateral-prone Position: Experience of 226 Cases.
Xu Li (2016)
Randomized clinical trial of landiolol hydrochloride for the prevention of atrial fibrillation and postoperative complications after oesophagectomy for cancer
Toshiyasu Ojima (2017)
Age and neo-adjuvant chemotherapy increase the risk of atrial fibrillation following oesophagectomy.
Vinay P. Rao (2012)
Surgical treatment of esophageal cancer in the era of multimodality management
Alicia S. Borggreve (2018)
Minimally invasive 3-field esophagectomy with cervical single-port access.
Hakan Guven (2014)
Atrial fibrillation after transhiatal esophagectomy with transcervical endoscopic esophageal mobilization: one institution’s experience
Elizabeth M Colwell (2018)
Initial experience of total thoracoscopic and laparoscopic Ivor Lewis esophagectomy.
Robert E. Merritt (2012)
Short-Term Outcomes of Minimally Invasive Esophagectomy for Carcinoma In Patients with Liver Cirrhosis.
Marco Sozzi (2017)
Preoperative Nomogram to Risk Stratify Patients for the Benefit of Trimodality Therapy in Esophageal Adenocarcinoma
Lucas Goense (2018)
Post-operative atrial fibrillation: a maze of mechanisms
Bart Maesen (2012)
Risk factors associated with atrial fibrillation after noncardiac thoracic surgery: analysis of 2588 patients.
Ara Asadur Vaporciyan (2004)
Chronic obstructive pulmonary disease predicts higher incidence and in hospital mortality for atrial fibrillation. An observational study using hospital discharge data in Spain (2004-2013).
Manuel Méndez-Bailón (2017)
The new onset of atrial arrhythmias following major noncardiothoracic surgery is associated with increased mortality.
D Brathwaite (1998)
The predictive value of new-onset atrial fibrillation on postoperative morbidity after esophagectomy.
Maarten F. J. Seesing (2018)
Analysis of risk factors for post-operative complications and prognostic predictors of disease recurrence following definitive treatment of patients with esophageal cancer from two medical centers in Northwest China
Jichang Wang (2017)
Diagnosis, assessment, and management of surgical complications following esophagectomy.
Peter P Grimminger (2018)
New-onset atrial fibrillation post-surgery for esophageal and junctional cancer: incidence, management, and impact on short- and long-term outcomes.
Orla Mc Cormack (2014)
Perioperative outcomes associated with robotic Ivor Lewis esophagectomy in patient's undergoing neoadjuvant chemoradiotherapy.
R Gadre Shridhar (2016)
[Treatment and follow-up for ovarian cancer].
Michiaki Yakushiji (1990)
Clinical research of atrial fibrillation complicated with esophagectomy of esophageal carcinoma
Xin Hua (2011)
Minimally Invasive Approach to Esophagectomy
James D. Luketich (1998)
Atrial remodeling and atrial fibrillation: recent advances and translational perspectives.
Stanley Nattel (2014)
This paper is referenced by
Intraoperative indocyanine green fluorescence angiography to prevent anastomotic leak after low anterior resection for rectal cancer: a meta-analysis.
Yu Shen (2020)
Enhanced recovery pathways vs standard care pathways in esophageal cancer surgery: systematic review and meta-analysis
Tania Triantafyllou (2020)