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Reproductive And Hormonal Risk Factors For Postmenopausal Luminal, HER‐2‐overexpressing, And Triple‐negative Breast Cancer

A. Phipps, K. Malone, P. Porter, J. Daling, C. Li
Published 2008 · Medicine

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Molecular profiling studies have identified subtypes of breast cancer that can be approximately classified by estrogen receptor (ER), progesterone receptor (PR), and HER‐2/neu (HER‐2) expression. These molecular subtypes are prognostically significant, but to the authors' knowledge, differences in their etiologic profiles have not been established. Reproductive factors may plausibly be differentially correlated with the risk of different breast cancer subtypes because these factors are presumed to impact exposure to endogenous sex hormones.
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