The Role Of Thyroid Fine‐needle Aspiration Cytology In The Pediatric Population: An Institutional Experience
E. Rossi, P. Straccia, M. Martini, L. Revelli, C. P. Lombardi, A. Pontecorvi, G. Fadda
Published 2014 · Medicine
Download PDFAnalyze on Scholarcy
The current study was conducted to investigate the role of thyroid fine‐needle aspiration cytology (FNAC) in the authors' pediatric series. Thyroid pediatric FNAC has been reported to have conflicting sensitivity and specificity in different series. The authors evaluated their thyroid cytological series mainly for the categories of 1) follicular/indeterminate neoplasms with atypical cells of indeterminate significance (FN/AUS) and 2) suspicious for malignancy (SM). In this setting, the application of immunocytochemistry (ICC) is likely to allow a correct diagnosis.
This paper references
Thyroid tumors in children and adolescents: preoperative study.
G. Ardito (2001)
Pediatric thyroid carcinoma: incidence and outcomes in 1753 patients.
A. Hogan (2009)
Paired box gene 8, HBME‐1, and cytokeratin 19 expression in preoperative fine‐needle aspiration of papillary thyroid carcinoma
A. Schmitt (2010)
Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology.
G. Fadda (2011)
Liquid-Based Cytology in Fine-Needle Aspiration Biopsies of the Thyroid Gland
G. Fadda (2011)
Immunocytochemistry with cytokeratin 19 and anti-human mesothelial cell antibody (HBME1) increases the diagnostic accuracy of thyroid fine-needle aspirations: preliminary report of 150 liquid-based fine-needle aspirations with histological control.
B. Cochand-Priollet (2011)
Indeterminate Pediatric Thyroid Fine Needle Aspirations: A Study of 68 Cases
M. Smith (2013)
Predictive factors of malignancy in pediatric thyroid nodules.
R. Roy (2011)
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS (AACE), ASSOCIAZIONE MEDICI ENDOCRINOLOGI (AME), AND EUROPEAN THYROID ASSOCIATION (ETA) MEDICAL GUIDELINES FOR CLINICAL PRACTICE FOR THE DIAGNOSIS AND MANAGEMENT OF THYROID NODULES
H. Gharib (2010)
Cost Impact of Molecular Testing for Indeterminate Thyroid Nodule Fine-Needle Aspiration Biopsies
L. Yip (2012)
The Bethesda System for Reporting Thyroid Cytopathology.
E. Cibas (2009)
Pathogenesis, diagnosis and management of thyroid nodules in children.
M. Niedziela (2006)
Thyroid Nodules in Pediatrics: Which Ones Can Be Left Alone, Which Ones Must be Investigated, When and How
A. Corrias (2013)
HBME-1 immunostaining in thyroid fine-needle aspirations: a useful marker in the diagnosis of carcinoma.
M. Sack (1997)
Thin layer compared to direct smear in thyroid fine needle aspiration
J. Scurry (2000)
Pediatric thyroid fine-needle aspiration cytology: a meta-analysis.
C. Stevens (2009)
Immunohistochemical Diagnosis of Papillary Thyroid Carcinoma
C. Cheung (2001)
Diagnostic features of thyroid nodules in pediatrics.
A. Corrias (2010)
Cytologic artifacts and pitfalls of thyroid fine‐needle aspiration using ThinPrep®
A. Afify (2001)
Use of molecular markers in samples obtained from preoperative aspiration of thyroid.
Homero Gustavo Correia Rodrigues (2012)
Cytological classification of thyroid nodules. Proposal of the SIAPEC-IAP Italian Consensus Working Group.
G. Fadda (2010)
Cytomorphological and molecular genetic findings in pediatric thyroid fine‐needle aspiration
S. Monaco (2012)
Management of thyroid nodules in children and adolescents.
W. Wiersinga (2007)
Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer.
D. Cooper (2009)
Accuracy of fine needle aspiration biopsy of thyroid nodules in detecting malignancy in childhood: comparison with conventional clinical, laboratory, and imaging approaches.
A. Corrias (2001)
American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and EuropeanThyroid Association Medical Guidelines for Clinical Practice for the Diagnosis and Management of Thyroid Nodules.
H. Gharib (2010)
Aggressive variants of follicular cell derived thyroid carcinoma; the so called ‘Real Thyroid Carcinomas’
Zubair W Baloch (2013)
Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules.
Y. Nikiforov (2009)
The Canadian Pediatric Thyroid Nodule Study: an evaluation of current management practices.
Chris Stevens (2008)
Pediatric thyroid nodules: disease demographics and clinical management as determined by fine needle aspiration biopsy.
S. Raab (1995)
Thyroidectomy in children: changing trends and surgical strategies.
M. Bagłaj (2013)
Fine-needle aspiration biopsy in the management of thyroid nodules in children and adolescents.
A. Al-Shaikh (2001)
Fine‐needle aspiration of follicular patterned lesions of the thyroid: Diagnosis, management, and follow‐up according to National Cancer Institute (NCI) recommendations
W. Faquin (2010)
The UK Royal College of Pathologists Thyroid Fine-Needle Aspiration Diagnostic Classification Is a Robust Tool for the Clinical Management of Abnormal Thyroid Nodules
C. Lobo (2011)
An analysis of fine-needle aspiration biopsy of the thyroid in children and adolescents.
B. M. Degnan (1996)
Pediatric thyroid nodules: management in the era of fine needle aspiration.
H. Lugo-Vicente (1998)
Cytopathologic analysis of thyroid lesions in the pediatric population
G. Hosler (2006)
Thyroid fine needle aspiration cytology processed by ThinPrep: an additional slide decreased the number of inadequate results
E. Rossi (2010)
Immunocytochemical evaluation of thyroid neoplasms on thin‐layer smears from fine‐needle aspiration biopsies
E. Rossi (2005)
Thyroid carcinoma in children and adolescents: diagnostic implications of analysis of the tumor genome
D. Zimmerman (2013)
Follicular-patterned lesions of the thyroid: the bane of the pathologist.
Z. Baloch (2002)
Contribution of molecular testing to thyroid fine‐needle aspiration cytology of “follicular lesion of undetermined significance/atypia of undetermined significance”
N. P. Ohori (2010)
Nodular Thyroid Disease in Children and Adolescents
B. Millman (1997)
PAX8 is expressed in anaplastic thyroid carcinoma diagnosed by fine-needle aspiration: a study of three cases with histological correlates.
C. Bellevicine (2013)
Diagnosis of “follicular neoplasm”: A gray zone in thyroid fine‐needle aspiration cytology
Z. Baloch (2002)
This paper is referenced by
Pediatric Thyroid Carcinoma in Patients with Graves' Disease: The Role of Ultrasound in Selecting Patients for Definitive Therapy
Kevin J Kovatch (2015)
Fine needle aspiration biopsy of thyroid nodules: cytologic and histopathologic correlation of 1096 patients.
C. Uğurluoğlu (2015)
The Etiology, Diagnosis and Treatment of Differentiated Thyroid Carcinoma in Children and Adolescents
Jiangqiao Geng (2014)
Cyto‐morphologic spectrum of thyroid lesions in children
P. Pathak (2018)
Histologic and clinical follow‐up of thyroid fine‐needle aspirates in pediatric patients
Kristen L Partyka (2016)
Fine needle aspiration cytology of thyroid nodules by liquid based cytology using LBC PREP2
Tomomi Yamaguchi (2017)
Cytologic features of aggressive variants of follicular‐derived thyroid carcinoma
E. Rossi (2019)
Noninvasive follicular thyroid neoplasm with papillary‐like nuclear features in the pediatric age group
E. Rossi (2018)
Immunohistochemical expression of HBME-1 and galectin-3 in the differential diagnosis of follicular-derived thyroid nodules.
Samar M. Abd-El Raouf (2014)
Cytological correlation of spectrum of head and neck lesions with epidemiological and diagnostic parameters
Rahul Mannan (2017)
The role of thyroid FNA cytology in pediatric malignant lesions: An overview of the literature
E. Rossi (2017)
Malignant risk of indeterminate pediatric thyroid nodules—An institutional experience
Amer Heider (2019)
Risk of malignancy for each Bethesda class in pediatric thyroid nodules.
O. Norlén (2015)
Morphological features that can predict BRAFV600E‐mutated carcinoma in paediatric thyroid cytology
E. Rossi (2017)
The role of fine-needle aspiration in the thyroid nodules of elderly patients
E. Rossi (2016)