Online citations, reference lists, and bibliographies.
← Back to Search

Polyacrylamide Grafted On Multi‐walled Carbon Nanotubes For Open‐tubular Capillary Electrochromatography: Comparison With Silica Hydride And Polyacrylate Phase Matrices

Jian-Lian Chen, Kai-Hsin Hsieh
Published 2010 · Chemistry, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
A new nanoparticle‐bound polymer stationary phase was prepared by in situ polymerization of methacrylamide (MAA), bis‐acrylamide crosslinker, and carboxylated multi‐walled carbon nanotubes (multi‐walled CNTs; MWNTs), using the abundant double bonds in the cyclopentadienyl rings in MWNT structure, on a silanized capillary. Each intermediate capillary between the synthesis steps was characterized by SEM, by ATR‐IR, and by EOF measurements varying the pH, concentration, and volumetric ratios of ACN in running buffers. The resulting EOF profile was comparable to those of two other capillaries with different phase matrices, silica hydride and polybutyl methacrylate (BMA) phases. With the complex functionality of MWNTs on the hydrophilic polyacrylamide network, the MAA‐CNT capillary was capable of separating diverse samples with a wide range of polarity and dissociation properties using open‐tubular CEC. Besides optimizing CEC conditions, the migration times of samples were analyzed with respect to velocity and retention factors to evaluate electrophoretic and chromatographic contributions to the CEC mechanism. The migration rates of benzoic acids were determined by the electrophoretic mobilities of the various phenolate ions, while phenolic aldehydes and ketones were additionally influenced by chromatographic interactions, such as π–π, electrostatic effects, hydrogen bonding, and hydrophobic interactions. The retention factors were greater for flavonoids, which are polyphenolic, than for simple phenols, but were smaller than those obtained from the hydrophobic BMA‐CNT column. A complete well‐resolved separation of the cationic forms of tetracyclines was acheived either by electrophoresis or by chromatography in the MAA‐CNT capillary, but not in the BMA‐CNT and silica hydride‐CNT capillaries.
This paper references
10.1002/elps.200700644
Polyacrylamide‐based monolithic capillary column with coating of cellulose tris(3,5‐dimethylphenyl‐carbamate) for enantiomer separation in capillary electrochromatography
X. Dong (2008)
10.1021/ac981175i
High-performance liquid chromatography of lignin-derived phenols in environmental samples with diode array detection.
J. R. Lobbes (1999)
10.1016/J.JBBM.2006.11.002
Porous polyacrylamide monoliths in hydrophilic interaction capillary electrochromatography of oligosaccharides.
V. Guryča (2007)
10.1016/j.chroma.2010.04.040
Succinyl methacrylate polymerized in porous-layered phases for open-tubular capillary electrochromatography: comparison with silica hydride monolayered phases.
Jian-Lian Chen (2010)
10.1002/ELPS.200600298
Recent progress in polar stationary phases for CEC
J. Ou (2007)
10.1002/elps.200800025
A mesoporous silica nanoparticles immobilized open‐tubular capillary column with a coating of cellulose tris(3,5‐dimethylphenyl‐carbamate) for enantioseparation in CEC
X. Dong (2008)
10.1002/APP.28754
Vinyl-carbon nanotubes for composite polymer materials
X. Kang (2008)
Colloids Surf
J. Lyklema (1998)
10.1002/elps.200800412
Recent progress of polar stationary phases in CEC and capillary liquid chromatography
X. Dong (2009)
10.1002/elps.200800142
Retention of proteins and metalloproteins in open tubular capillary electrochromatography with etched chemically modified columns
J. Pesek (2008)
Spectrometric Identification of Organic Compounds, 7th Edn
R M Silverstein (2005)
10.1021/AC00221A013
Electrophoretic separations of proteins in capillaries with hydrolytically stable surface structures.
K. Cobb (1990)
10.1002/ELPS.200500462
Titanium dioxide nanoparticles‐coated column for capillary electrochromatographic separation of oligopeptides
Yi-Ling Hsieh (2005)
10.1002/JSSC.200500317
Capillary electrochromatography of amino acids with a protein-bonded porous-layer open-tubular column.
T. Huang (2006)
10.1016/j.chroma.2009.12.018
Multi-wall carbon nanotubes bonding on silica-hydride surfaces for open-tubular capillary electrochromatography.
Jian-Lian Chen (2010)
10.1002/ELPS.200600259
Open‐tubular capillary columns with a porous layer of monolithic polymer for highly efficient and fast separations in electrochromatography
S. Eeltink (2006)
10.1016/j.chroma.2008.10.001
Polydopamine-based permanent coating capillary electrochromatography for auxin determination.
Xue-Bo Yin (2008)
10.1016/0021-9673(96)00306-8
Separation parameters via virtual migration distances in high-performance liquid chromatography, capillary zone electrophoresis and electrokinetic chromatography.
A. Rathore (1996)
10.1021/AC048544X
Gold nanoparticle-modified etched capillaries for open-tubular capillary electrochromatography.
L. Yang (2005)
10.1016/S0021-9673(01)95485-8
High-performance electrophoresis : Elimination of electroendosmosis and solute adsorption
S. Hjertén (1985)
10.1016/J.CHROMA.2007.06.072
Separation mechanism and determination of flavanones with capillary electrophoresis and high-performance liquid chromatography.
S. Wang (2007)
10.1016/J.CHROMA.2003.07.018
Capillary zone electrophoresis in non-aqueous solutions: pH of the background electrolyte.
S. P. Porras (2004)
10.1002/ELPS.200500628
Metallomesogenic stationary phase for open‐tubular capillary electrochromatography
Jian-Lian Chen (2006)
10.1016/J.COMPSCITECH.2008.08.011
Functionalization of MWNTs using polyacryloyl chloride and the properties of CNT–epoxy matrix nanocomposites
W. Zou (2008)
10.1021/AC9900735
Electrosmotic mobility and conductivity in columns for capillary electrochromatography.
A. Rathore (1999)
10.1039/J39710002164
Experiments on the synthesis of tetracycline. Part I. Introduction to the series
D. H. Barton (1971)
10.2116/ANALSCI.26.561
Capillary electrophoretic determination of selected phenolic compounds in humic substances of well waters and fertilizers.
Mei-Ying Chen (2010)
10.1002/elps.200700400
Novel open tubular CEC with tentacle‐type polymer stationary phase functionalized by phenylalanine
L. Xu (2008)
10.1016/j.chroma.2007.12.083
Protein separation by open tubular capillary electrochromatography employing a capillary coated with phenylalanine functionalized tentacle-type polymer under both cathodic and anodic electroosmotic flows.
L. Xu (2008)
10.1002/1522-2683(200205)23:9<1211::AID-ELPS1211>3.0.CO;2-B
Chromatographic and electrophoretic migration parameters in capillary electrochromatography
A. Rathore (2002)
10.1016/J.CHROMA.2007.09.027
Developments in the use and fabrication of organic monolithic phases for use with high-performance liquid chromatography and capillary electrochromatography.
N. Smith (2008)
10.1016/S0167-577X(02)00863-7
Non-destructive purification of multi-walled carbon nanotubes produced by catalyzed CVD
X. Chen (2002)
10.1016/J.CARBON.2009.03.060
Dimensional control of multi-walled carbon nanotubes in floating-catalyst CVD synthesis
Gregg S. B. McKee (2009)
10.1002/elps.200800683
Rapid analysis of peptides and amino acids by CE‐ESI‐MS using chemically modified fused‐silica capillaries
M. Lu (2009)
10.1021/la900852p
Molecular structures of citrate and tricarballylate adsorbed on alpha-FeOOH particles in aqueous suspensions.
Malin Lindegren (2009)
10.1016/S0927-7757(97)00266-5
On surface conduction and its role in electrokinetics.
J. Lyklema (1998)
10.1021/AC960894Z
Preparation and evaluation of bonded linear polymethacrylate stationary phases for open tubular capillary electrokinetic chromatography
Z. Tan (1997)
10.1002/elps.200800359
Chip‐based enantioselective open‐tubular capillary electrochromatography using bovine serum albumin‐gold nanoparticle conjugates as the stationary phase
H. Li (2009)
10.1016/S0021-9673(97)00626-2
Dynamics of capillary electrochromatography experimental study on the electrosmotic flow and conductance in open and packed capillaries.
G. Choudhary (1997)
10.1007/978-3-642-50687-1
Handbuch der Elektricität und des Magnetismus
O. Froelich (1887)
10.1002/elps.201000226
Multi‐walled carbon nanotube composites with polyacrylate prepared for open‐tubular capillary electrochromatography
Jian-Lian Chen (2010)
10.1016/j.chroma.2009.07.017
Comparision of succinate- and phthalate-functionalized etched silica hydride phases for open-tubular capillary electrochromatography.
Jian-Lian Chen (2009)
10.1002/elps.200800275
Carboxylic multi‐walled carbon nanotubes as immobilized stationary phase in capillary electrochromatography
L. Sombra (2008)
10.1016/J.CHROMA.2007.07.018
Use of nanoparticles in capillary and microchip electrochromatography.
C. Nilsson (2007)
10.1002/MARC.200300089
Synthesis and Dispersion Characteristics of Multi‐Walled Carbon Nanotube Composites with Poly(methyl methacrylate) Prepared by In‐Situ Bulk Polymerization
S. J. Park (2003)
10.1093/AJHP/33.12.1316
Drug Treatment: Principles and Practice of Clinical Pharmacology and Therapeutics
R. Scheife (1976)
10.1039/J39710002164
Experiments on the synthesis of tetracycline. I. Introduction to the series.
Barton Dh (1971)
10.1021/AC061871F
Hydrophilic interaction chromatography using methacrylate-based monolithic capillary column for the separation of polar analytes.
Zhengjin Jiang (2007)
10.1080/10826070903248411
Open Tubular Capillary Electrochromatographic Separation of Proteins and Peptides Using a TiO2 Nanoparticle-Deposited Capillary by Liquid Phase Deposition
Ting Li (2009)
10.1128/AAC.4.1.11
Separation and Detection of Tetracyclines by High-Speed Liquid Chromatography
A. Butterfield (1973)
10.1016/S0921-5093(99)00263-4
Study on poly(methyl methacrylate)/carbon nanotube composites
Zhijie Jia (1999)
10.1016/0924-2031(92)87024-A
Spectrometric Identification of Organic Compounds
Gary W Small (1992)
10.1016/j.chroma.2008.08.015
Preparation of an open-tubular capillary column with a monolithic layer of S-ketoprofen imprinted and 4-styrenesulfonic acid incorporated polymer and its enhanced chiral separation performance in capillary electrochromatography.
S. Zaidi (2009)
10.1002/elps.200800558
Novel negatively charged tentacle‐type polymer coating for on‐line preconcentration of proteins in CE
L. Xu (2009)
10.1007/BF02321428
Electrochromatography in packed tubes using 1.5 to 50 μm silica gels and ODS bonded silica gels
J. Knox (1991)
10.1021/J100895A062
Electrokinetic Flow in a Narrow Cylindrical Capillary
C. L. Rice (1965)
10.1016/J.CHROMA.2004.05.054
Influence of moderate Joule heating on electroosmotic flow velocity, retention, and efficiency in capillary electrochromatography.
Guofang Chen (2004)
10.1016/J.WATRES.2004.03.017
Potentiometric determination of acid dissociation constants (pKa) for human and veterinary antibiotics.
Z. Qiang (2004)
10.1021/JA01134A521
TERRAMYCIN. VI. THE STRUCTURE OF α- AND β-APOTERRAMYCIN, ACID REARRANGEMENT PRODUCTS OF TERRAMYCIN
F. Hochstein (1952)
10.1201/9781315274287
Principles of colloid and surface chemistry
P. C. Hiemenz (1977)
10.1016/S0021-9673(99)00795-5
Capillary electrochromatography of proteins and peptides with porous-layer open-tubular columns.
X. Huang (1999)
10.1016/J.CHROMA.2004.04.070
Polystyrene monolithic column functionalized with copper-iminodiacetate complex as a stationary phase for open tubular capillary electrochromatography.
S. Chuang (2004)
10.1002/elps.200800841
Etched succinate‐functionalized silica hydride stationary phase for open‐tubular CEC
Jian-Lian Chen (2009)
10.1002/jps.2600601024
Paper chromatographic determination of oxytetracycline.
A. Siña (1971)
10.1002/ELPS.200600714
Fabrication and characterization of open‐tubular CEC modified with tentacle‐type metal‐chelating polymer chains
L. Xu (2007)



This paper is referenced by
10.1016/j.msec.2018.11.026
Buchwald-Hartwig C-N cross coupling reactions catalyzed by palladium nanoparticles immobilized on thio modified-multi walled carbon nanotubes as heterogeneous and recyclable nanocatalyst.
H. Veisi (2019)
10.1016/J.CATTOD.2017.04.040
WITHDRAWN: Multi walled carbon nanotubes modified with mercapto-melamine groups for the stabilization of palladium nanoparticles: An efficient nanocatalyst for the Suzuki reaction in aqueous media under mild conditions
H. Veisi (2017)
10.1007/978-3-319-69378-1_4
Physical, Mechanical, and Thermal Properties of CNTs
P. Chandrasekhar (2018)
10.1016/j.chroma.2013.07.107
Comprehensive overview of recent preparation and application trends of various open tubular capillary columns in separation science.
W. Cheong (2013)
10.1016/j.talanta.2013.01.039
Visual detection of tetracycline antibiotics with the turned on fluorescence induced by a metal-organic coordination polymer.
Fei Leng (2013)
10.1007/978-3-642-35043-6_9
Electrochromatographic Methods: Capillary Electrochromatograpy
M. Szumski (2013)
10.1007/978-3-319-69378-1_25
Graphene Applications in Specialized Materials
P. Chandrasekhar (2018)
10.1002/elps.201700462
Preparation of β‐cyclodextrin‐gold nanoparticles modified open tubular column for capillary electrochromatographic separation of chiral drugs
L. Zhou (2018)
10.1021/acsami.6b13949
Conjugated Polyelectrolyte Based Sensitive Detection and Removal of Antibiotics Tetracycline from Water.
A. H. Malik (2017)
10.1007/978-3-319-69378-1_8
CNT Applications in Batteries and Energy Devices
P. Chandrasekhar (2018)
10.1007/978-3-319-69378-1_28
Conduction Models and Electronic Structure of CNTs
P. Chandrasekhar (2018)
10.1016/J.APMT.2017.09.008
Carbon nanotubes as analytical tools in capillary electromigration methods
M. Moreno (2017)
10.1007/978-3-319-69378-1_13
CNT Applications in Electrical Conductors, “Quantum Nanowires,” and Potential Superconductors
P. Chandrasekhar (2018)
10.1007/978-3-319-69378-1_7
CNT Applications in Specialized Materials
P. Chandrasekhar (2018)
10.1007/978-3-319-69378-1_27
Introducing Conducting Polymers (CPs)
P. Chandrasekhar (2018)
10.1007/978-3-319-69378-1_42
Electrochemomechanical, Chemomechanical, and Related Devices
P. Chandrasekhar (2018)
10.1007/978-3-319-69378-1_5
Toxicology of CNTs
P. Chandrasekhar (2018)
10.3923/AJSR.2014.303.311
Lotus-leaf Inspired Hydrophobic Nanocomposite Matrices for Electrophoretic Separation of Bacterial Outer Membrane Proteins
Lourdusamy Arul Antony Mar (2014)
10.1016/J.POLY.2019.01.070
Suzuki–Miyaura reaction by heterogeneously supported Pd nanoparticles on thio-modified multi walled carbon nanotubes as efficient nanocatalyst
H. Veisi (2019)
10.1007/978-3-319-69378-1_30
Basic Electrochemistry of CPs
P. Chandrasekhar (2018)
10.1002/9781118530009.CH6
Improving the Separation in Microchip Electrophoresis by Surface Modification
M. T. Fernández-Abedul (2013)
10.1007/978-81-322-2470-9_6
Multifunctionalized Carbon Nanotubes Polymer Composites: Properties and Applications
N. M. Julkapli (2015)
10.1016/j.aca.2013.03.041
Analytical application of carbon nanotubes, fullerenes and nanodiamonds in nanomaterials-based chromatographic stationary phases: a review.
Andrea Speltini (2013)
10.1007/978-3-319-69378-1_37
Batteries and Energy Devices
P. Chandrasekhar (2018)
10.1016/j.aca.2012.04.035
Carbon nanotubes applications in separation science: a review.
Antonio V. Herrera-Herrera (2012)
10.1007/978-3-319-69378-1_10
CNT Applications in Drug and Biomolecule Delivery
P. Chandrasekhar (2018)
10.1007/978-3-319-69378-1_14
CNT Applications in the Environment and in Materials Used in Separation Science
P. Chandrasekhar (2018)
10.1016/j.chroma.2014.04.003
Room temperature fabrication of post-modified zeolitic imidazolate framework-90 as stationary phase for open-tubular capillary electrochromatography.
L. Yu (2014)
10.1007/978-3-319-69378-1_12
Graphene Applications in Displays and Transparent, Conductive Films/Substrates
P. Chandrasekhar (2018)
10.1007/978-3-319-69378-1_32
Structural Aspects and Morphology of CPs
P. Chandrasekhar (2018)
10.1007/978-3-319-69378-1_9
CNT Applications in Sensors and Actuators
P. Chandrasekhar (2018)
10.1007/978-3-319-69378-1_21
Graphene Applications in Batteries and Energy Devices
P. Chandrasekhar (2018)
See more
Semantic Scholar Logo Some data provided by SemanticScholar