Online citations, reference lists, and bibliographies.
← Back to Search

Anterior Cingulate Cortex: An FMRI Analysis Of Conflict Specificity And Functional Differentiation

M. Milham, M. Banich
Published 2005 · Psychology, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
In this event‐related functional magnetic resonance imaging (fMRI) study, we provide evidence that the role of the anterior cingulate cortex (ACC) in cognitive control may not be unitary, as the responses of different ACC subregions vary depending upon the nature of task‐irrelevant information. More specifically, using the color‐word Stroop task (congruent, incongruent, and neutral trial types), we examined the degree to which increases in neural activity within ACC are specific to conditions of conflict, as posited by the conflict monitoring theory (Botvinick et al. [1999]: Rev Neurosci 10:49–57; Carter et al. [ 1998 ]: Science 280:747–749). Although incongruent and congruent trials both involve two competing sources of color information (color word and ink color), only incongruent trials involve a direct conflict between task‐relevant and task‐irrelevant information. Although the anterior division of the ACC rostral zone exhibited conflict specific increases in neural activity (i.e., incongruent > congruent = neutral), the posterior division exhibited a more generalized pattern, increasing whenever the task‐irrelevant information was color related, regardless of whether it was conflicting (i.e., incongruent and congruent > neutral). Our data thus suggest a possible functional differentiation within the ACC. As such, it is unlikely that the role of the ACC in cognitive control will be able to be accommodated by a single unifying theory. Hum Brain Mapp, 2005. © 2005 Wiley‐Liss, Inc.
This paper references
10.1037/H0021284
Choice reaction times to hues printed in conflicting hue names and nonsense words.
B. Gholson (1968)
10.1037/H0035245
Interference and facilitation for color naming with separate bilateral presentations of the word and color.
F. Dyer (1973)
10.3758/BF03197574
Selective attention between words, shapes and colors in speeded classification and vocalization tasks
J. Flowers (1977)
10.1037/0096-1523.8.6.875
Time course analysis of the Stroop phenomenon.
M. Glaser (1982)
Co-Planar Stereotaxic Atlas of the Human Brain: 3-Dimensional Proportional System: An Approach to Cerebral Imaging
J. Talairach (1988)
10.1038/jcbfm.1989.13
A Highly Accurate Method of Localizing Regions of Neuronal Activation in the Human Brain with Positron Emission Tomography
Mark A. Mintun (1989)
10.1016/S0009-9260(05)80985-7
Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268
M. Torrens (1990)
10.1037/0033-2909.109.2.163
Half a century of research on the Stroop effect: an integrative review.
Colin M. Macleod (1991)
10.1152/JN.1993.70.2.453
Role of the human anterior cingulate cortex in the control of oculomotor, manual, and speech responses: a positron emission tomography study.
T. Paus (1993)
10.1002/MRM.1910330508
Improved Assessment of Significant Activation in Functional Magnetic Resonance Imaging (fMRI): Use of a Cluster‐Size Threshold
S. Forman (1995)
10.1126/SCIENCE.280.5364.747
Anterior cingulate cortex, error detection, and the online monitoring of performance.
C. Carter (1998)
10.1016/S1361-8415(98)80009-1
Three-dimensional multi-scale line filter for segmentation and visualization of curvilinear structures in medical images
Y. Sato (1998)
10.1073/PNAS.97.4.1944
Parsing executive processes: strategic vs. evaluative functions of the anterior cingulate cortex.
C. Carter (2000)
10.1111/1469-8986.3720216
Error processing and the rostral anterior cingulate: an event-related fMRI study.
K. Kiehl (2000)
10.1038/74899
Prefrontal–cingulate interactions in action monitoring
W. Gehring (2000)
10.1016/S1053-8119(00)91037-1
Anterior cingulate cortex and response conflict: Effects of response modality and processing domain
D. Barch (2000)
10.1162/08989290051137521
fMRI Studies of Stroop Tasks Reveal Unique Roles of Anterior and Posterior Brain Systems in Attentional Selection
M. Banich (2000)
10.1016/S0926-6410(01)00076-3
The relative involvement of anterior cingulate and prefrontal cortex in attentional control depends on nature of conflict.
M. Milham (2001)
10.1016/S1361-8415(01)00036-6
A global optimisation method for robust affine registration of brain images
M. Jenkinson (2001)
10.1093/CERCOR/11.9.837
Anterior Cingulate Cortex and Response Conflict: Effects of Response Modality and Processing Domain
M. Deanna (2001)
10.1006/nimg.2001.0931
Temporal Autocorrelation in Univariate Linear Modeling of FMRI Data
M. Woolrich (2001)
10.1093/CERCOR/11.9.825
Anterior cingulate cortex and response conflict: effects of frequency, inhibition and errors.
T. Braver (2001)
10.1038/35077500
Primate anterior cingulate cortex: Where motor control, drive and cognition interface
T. Paus (2001)
10.1073/pnas.152694799
The role of the parietal cortex in visual feature binding
Keith M. Shafritz (2002)
10.1006/brcg.2001.1501
Attentional Control in the Aging Brain: Insights from an fMRI Study of the Stroop Task
M. Milham (2002)
10.1016/j.tics.2004.10.003
Conflict monitoring and anterior cingulate cortex: an update
M. Botvinick (2004)



This paper is referenced by
10.1016/j.biopsych.2021.08.020
Midfrontal theta activity in psychiatric illness: an index of cognitive vulnerabilities across disorders
G. McLoughlin (2021)
10.1371/journal.pone.0248006
The Prisoner’s Dilemma paradigm provides a neurobiological framework for the social decision cascade
Khalil Thompson (2021)
10.1159/000511605
Theta-Burst Stimulation Is Able to Impact Cognitive Processing: A P300 and Neuropsychological Test Study
Nuno Pinto (2021)
10.1016/j.dcn.2020.100826
Neonatal brain volume as a marker of differential susceptibility to parenting quality and its association with neurodevelopment across early childhood
S. Nolvi (2020)
10.1016/j.bbr.2020.112544
Resting-state functional connectivity of the anterior cingulate cortex in young adults depressed patients with and without suicidal behavior
H. Qiu (2020)
10.1017/S0033291720000434
Sub-regional anterior cingulate cortex functional connectivity revealed default network subsystem dysfunction in patients with major depressive disorder
Xiaolong Peng (2020)
10.1371/journal.pone.0234104
Emojis influence autobiographical memory retrieval from reading words: An fMRI-based study
C. Chatzichristos (2020)
10.1016/j.schres.2020.03.072
Impulsive decision making, brain cortical thickness and familial schizophrenia risk
A. B. Barry (2020)
Error-related brain activity reflects independent systems in human error monitoring [cumulative dissertation]
F. Gregorio (2019)
10.1371/journal.pone.0210736
A functional MRI investigation of crossmodal interference in an audiovisual Stroop task
Megan C. Fitzhugh (2019)
10.3389/fpsyg.2019.02164
The Stroop Effect Occurs at Multiple Points Along a Cascade of Control: Evidence From Cognitive Neuroscience Approaches
M. Banich (2019)
10.1038/s41598-019-40277-3
A fine-grained time course investigation of brain dynamics during conflict monitoring
Paolo Ruggeri (2019)
10.1016/j.actpsy.2019.04.016
It's more than just conflict: The functional role of congruency in the sequential control adaptation.
Anja Berger (2019)
10.3389/fnhum.2019.00101
The Immediate and Sustained Positive Effects of Meditation on Resilience Are Mediated by Changes in the Resting Brain
S. Kwak (2019)
10.3389/fnins.2019.00123
Prenatal Protein Malnutrition Produces Resistance to Distraction Similar to Noradrenergic Deafferentation of the Prelimbic Cortex in a Sustained Attention Task
L. A. Newman (2019)
10.1002/cne.24804
The functional anatomy of cognitive control: A domain‐general brain network for uncertainty processing
Tingting Wu (2019)
10.1016/j.neuroimage.2017.10.023
Overlapping and distinct neural correlates of imitating and opposing facial movements
Detre A. Godinez (2018)
10.1016/j.jpsychires.2017.11.008
Impulsivity in unaffected adolescent biological relatives of schizophrenia patients.
B. Ho (2018)
10.1038/s10038-018-0418-y
Nature vs. nurture in human sociality: multi-level genomic analyses of social conformity
Biqing Chen (2018)
10.1111/psyp.13060
Emerging themes in cognitive control: Commentary on the special issue of Psychophysiology entitled "Dynamics of Cognitive Control: A View Across Methodologies".
M. Banich (2018)
10.3389/fnhum.2018.00464
Modulating Effects of Contextual Emotions on the Neural Plasticity Induced by Word Learning
Jingjing Guo (2018)
10.1007/s10072-017-3104-5
An fMRI paradigm based on Williams inhibition test to study the neural substrates of attention and inhibitory control
A. Dores (2017)
10.1101/149567
Beyond Consensus: Embracing Heterogeneity in Neuroimaging Meta-Analysis
Gia H. Ngo (2017)
10.1093/cercor/bhw350
Distinct Roles for the Anterior Cingulate and Dorsolateral Prefrontal Cortices During Conflict Between Abstract Rules
E. Boschin (2017)
Exploring the Relationship between Motor and Frontoparietal Brain Networks in Upper Limb Motor Outcome Post-stroke
Timothy K. Lam (2016)
A dimensional assessment of an implicit measure of emotion regulation
Benjamin O Emmert-Aronson (2016)
10.1016/j.bandc.2016.03.008
Functional independence in resting-state connectivity facilitates higher-order cognition
G. James (2016)
10.1016/j.bbr.2016.03.004
Cerebral white matter correlates of delay discounting in adolescents
B. Ho (2016)
10.1002/hbm.23219
Functional connectivity at rest is sensitive to individual differences in executive function: A network analysis
A. E. Reineberg (2016)
Dissociable sources of uncertainty in perceptual decision making
E. Michael (2016)
10.1037/dev0000074
The Development of Stimulus and Response Interference Control in Midchildhood
Lucy Cragg (2016)
10.4236/JBBS.2016.69035
Dysregulation within the Prefronto-Parietal Background-Monitoring Network in Schizophrenia
S. Wolter (2016)
See more
Semantic Scholar Logo Some data provided by SemanticScholar