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P51/p63, A Novel P53 Homologue, Potentiates P53 Activity And Is A Human Cancer Gene Therapy Candidate

R. Kunisaki, S. Ikawa, T. Maeda, Y. Nakazaki, R. Kurita, M. Harata, Y. Shutoh, Y. S. Bai, Yasushi Soda, T. Tanabe, T. Dohi, R. Kato, Y. Ikawa, S. Asano, K. Tani
Published 2006 · Biology, Medicine

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p51 (p73L/p63/p40/KET), a recently isolated novel p53 homologue, binds to p53‐responsive elements to upregulate some p53 target genes and has been suggested to share partially overlapping functions with p53. p51 may be a promising candidate target molecule for anti‐cancer therapy.
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