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Actin-Binding Proteins And Disease
C. Remedios, D. Chhabra
Published 2008 · Chemistry
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What is PIP2? Phosphatidylinositol(4,5) bisphosphate (PI(4,5)P2 or more simply, PIP2) is only a minor component of the cell membrane lipids but it is the most abundant of the bisphorylated phosphoinositides. PIP2 is a key ligand in regulating the activity of a number of actin-binding proteins that regulate the assembly of actin microfilaments (Logan and Mandato 2006; Yin and Janmey 2003). Because of its central role, abnormal accumulation of PIP2 in the cell might be expected to produce defects in the assembly of cytoplasmic actin microfilaments. Similarly, a substantial reduction in cellular PIP2 is also not likely to be tolerated. Thus, mutations in enzymes that control cellular PIP2 content may be responsible, either directly or indirectly, for a number of human diseases/disorders.
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Cofactor Requirements for Nuclear Export of Rev Response Element (Rre)–And Constitutive Transport Element (Cte)–Containing Retroviral Rnas
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Lasp‐1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains
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Cell motility as a prognostic factor in Stage I nonsmall cell lung carcinoma
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The Shank Family of Postsynaptic Density Proteins Interacts with and Promotes Synaptic Accumulation of the βPIX Guanine Nucleotide Exchange Factor for Rac1 and Cdc42*
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Activation of Endogenous Cdc42 Visualized in Living Cells
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Molecular and Cell Biology of TGF-β
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Structural interpretation of the mutations in the beta-cardiac myosin that have been implicated in familial hypertrophic cardiomyopathy.
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How profilin promotes actin filament assembly in the presence of thymosin β4
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Angiopathic consequences of saturating the plasma scavenger system for actin.
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In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly
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Cytoplasmic localization and nuclear transport of cofilin in cultured myotubes.
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Induction of neuron-specific tropomyosin mRNAs by nerve growth factor is dependent on morphological differentiation
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Nuclear actin and myosin I are required for RNA polymerase I transcription
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Characterization of Palladin, a Novel Protein Localized to Stress Fibers and Cell Adhesions
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Cofilin (ADF) affects lateral contacts in F-actin.
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The Mouse Formin mDia1 Is a Potent Actin Nucleation Factor Regulated by Autoinhibition
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Utrophin upregulation for treating Duchenne or Becker muscular dystrophy: how close are we?
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Vessels and Nerves: Marching to the Same Tune
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Solution Structure of Human Cofilin
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Differential Expression of Vinculin between Weakly and Highly Metastatic B16‐Melanoma Cell Lines
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Strategies of epithelial repair: modulation of stem cell and transit amplifying cell proliferation.
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Smn, the spinal muscular atrophy–determining gene product, modulates axon growth and localization of β-actin mRNA in growth cones of motoneurons
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Cytoplasmic Actin: A Comparative Study
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Conformational difference between nuclear and cytoplasmic actin as detected by a monoclonal antibody.
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Mutant myosin VIIa causes defective melanosome distribution in the RPE of shaker-1 mice
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Transgenic Nude Mouse with Ubiquitous Green Fluorescent Protein Expression as a Host for Human Tumors
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Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro.
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The extracellular actin-scavenger system and actin toxicity.
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Proteomic analysis of NMDA receptor–adhesion protein signaling complexes
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Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity
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Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation
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Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia
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Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor.
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Cell Migration: A Physically Integrated Molecular Process
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Crystal structure of the actin-binding protein actophorin from Acanthamoeba
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Protein-protein interactions in the rigor actomyosin complex.
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Antibody to smooth muscle in patients with liver disease.
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Studies on the exchange of G-actin-bound calcium with bivalent cations.
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GFP expression in the mammary gland for imaging of mammary tumor cells in transgenic mice.
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Expression of Myopodin Induces Suppression of Tumor Growth and Metastasis
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The deficiency of PIP2 5-phosphatase in Lowe syndrome affects actin polymerization.
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Physical mapping and genomic structure of the Lowe syndrome gene OCRL1
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Pak to the future.
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Mutations in the γ-Actin Gene (ACTG1) Are Associated with Dominant Progressive Deafness (DFNA20/26)
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Regulation of the actin cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.
P. Hilpelä (2004)
Gelsolin inhibits the fibrillization of amyloid beta-protein, and also defibrillizes its preformed fibrils
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Phage display for epitope determination: a paradigm for identifying receptor-ligand interactions.
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Frequent loss of gelsolin expression in non-small cell lung cancers of heavy smokers.
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The Leukemic Protein Core Binding Factor β (CBFβ)–Smooth-Muscle Myosin Heavy Chain Sequesters CBFα2 into Cytoskeletal Filaments and Aggregates
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The tightly bound divalent cation regulates actin polymerization.
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Proteome analysis of human substantia nigra in Parkinson's disease
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The role of magnesium in the relaxation of myofibrils.
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Binding of nucleotide to cation-free G-action.
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Aczonin, a 550-Kd Putative Scaffolding Protein of Presynaptic Active Zones, Shares Homology Regions with Rim and Bassoon and Binds Profilin
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Identification of differentially expressed genes like cofilin2 in growing collateral arteries.
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Actophorin preferentially binds monomeric ADP‐Actin over ATP‐bound actin: consequences for cell locomotion
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Stimulation of actin synthesis in phalloidin‐treated cells
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The neurofibromatoses: when less is more.
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The actin binding site of thymosin beta 4 mapped by mutational analysis.
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Conformation of thymosin β4 in water determined by NMR spectroscopy
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Structure of gelsolin segment 1-actin complex and the mechanism of filament severing
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Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene
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Identification of profilin as a novel pollen allergen; IgE autoreactivity in sensitized individuals.
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FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.
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Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression.
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Interplay between components of a novel LIM kinase–slingshot phosphatase complex regulates cofilin
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Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells
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Loss of calponin h1 in renal angiomyolipoma correlates with aggressive clinical behavior.
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MEK Mediates v-Src-induced Disruption of the Actin Cytoskeleton via Inactivation of the Rho-ROCK-LIM Kinase Pathway*
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Corneal epithelial disease.
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Cell adhesion receptors, tyrosine kinases and actin modulators: a complex three-way circuitry.
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Congenital myopathies: diseases of the actin cytoskeleton
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A cofilin-like protein is involved in the regulation of actin assembly in developing skeletal muscle.
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SEPN1: Associated with congenital fiber‐type disproportion and insulin resistance
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Nemaline myopathy caused by absence of α‐skeletal muscle actin
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Targeting of a tropomyosin isoform to short microfilaments associated with the Golgi complex.
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Defective myosin VIIA gene responsible for Usher syndrome type IB
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Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition.
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Integrin αIIbβ3 signals lead cofilin to accelerate platelet actin dynamics
H. Falet (2005)
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Deconstructing the Cadherin-Catenin-Actin Complex
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Use of thymosin β15 as a urinary biomarker in human prostate cancer
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Novel testis-expressed profilin IV associated with acrosome biogenesis and spermatid elongation.
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Actin binding proteins: regulation of cytoskeletal microfilaments.
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The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
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Abnormal Spine Morphology and Enhanced LTP in LIMK-1 Knockout Mice
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F‐actin‐like filaments formed by plasmid segregation protein ParM
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Increased importin-β-dependent nuclear import of the actin modulating protein CapG promotes cell invasion
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Tropomyosin and Troponin Regulation of Wild Type and E93K Mutant Actin Filaments from Drosophila Flight Muscle
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A screen for modifiers of RacGAP(84C) gain-of-function in the Drosophila eye revealed the LIM kinase Cdi/TESK1 as a downstream effector of Rac1 during spermatogenesis
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Mammals Have Two Twinfilin Isoforms Whose Subcellular Localizations and Tissue Distributions Are Differentially Regulated*
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Calcium regulation of gelsolin and adseverin: a natural test of the helix latch hypothesis.
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A new locus for late-onset, progressive, hereditary hearing loss DFNA20 maps to 17q25.
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Autoregulation of actin synthesis responds to monomeric actin levels
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Proteomic changes in renal cancer and co‐ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect
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Actin polymerization and ATP hydrolysis.
M. Carlier (1990)
Autosomal dominant nemaline myopathy with intranuclear rods due to mutation of the skeletal muscle ACTA1 gene: Clinical and pathological variability within a kindred
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The cooperative nature of G-F transformation of actin.
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Defective Actin Reorganization and Polymerization of Wiskott-Aldrich T Cells in Response to CD3-Mediated Stimulation
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Defining α-skeletal and α-cardiac actin expression in human heart and skeletal muscle explains the absence of cardiac involvement in ACTA1 nemaline myopathy
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Protein kinase C isozyme-specific phosphorylation of profilin.
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Filopodia, Spines, and the Generation of Synaptic Diversity
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Beta-thymosins from marine invertebrates: primary structure and interaction with actin.
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Muscle fiber type transformation in nemaline myopathy and congenital fiber type disproportion
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Epidemic listeriosis--evidence for transmission by food.
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Real-time imaging of myosin II regulatory light-chain phosphorylation using a new protein biosensor.
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Delphilin: a Novel PDZ and Formin Homology Domain-Containing Protein that Synaptically Colocalizes and Interacts with Glutamate Receptor δ2 Subunit
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Human smooth muscle autoantibody. Its identification as antiactin antibody and a study of its binding to "nonmuscular" cells.
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Amplification-independent overexpression of thymosin beta-10 mRNA in human renal cell carcinoma.
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The oculocerebrorenal syndrome of lowe
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LIM kinase 1: evidence for a role in the regulation of intracellular vesicle trafficking of lysosomes and endosomes in human breast cancer cells.
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Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide.
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Eosinophilic bodies in some neurones in the thalamus of ageing mice
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Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex
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Functional plasticity of CH domains
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Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines.
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Organic-aciduria, decreased renal ammonia production, hydrophthalmos, and mental retardation; a clinical entity.
C. Lowe (1952)
LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics
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Intracellular pH modulation of ADF/cofilin proteins.
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Actin-dependent movement of bacterial pathogens
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The complexity of PTEN: mutation, marker and potential target for therapeutic intervention
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Nuclear actin bundles in Amoeba, Dictyostelium and human HeLa cells induced by dimethyl sulfoxide.
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In the cochlea
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Platelet-released phospholipids link haemostasis and angiogenesis.
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Recombinant Plasma Gelsolin Diminishes the Acute Inflammatory Response to Hyperoxia in Mice
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Chapter 3 – Macromolecular Assembly of Actin
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Espin gene (ESPN) mutations associated with autosomal dominant hearing loss cause defects in microvillar elongation or organisation
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A matter of life and death.
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Structure of the Mammalian Cochlea
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The actin cytoskeleton as a therapeutic target: state of the art and future directions.
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Furin at the cutting edge: From protein traffic to embryogenesis and disease
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Characterization of functional domains of mDia1, a link between the small GTPase Rho and the actin cytoskeleton.
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Interactions of Acanthamoeba profilin with actin and nucleotides bound to actin.
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Actin lessons from pathogens.
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Tumor suppressor activity of profilin requires a functional actin binding site.
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Imaging Sites of N-WASP Activity in Lamellipodia and Invadopodia of Carcinoma Cells
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Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced.
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The Crystal Structure of Uncomplexed Actin in the ADP State
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Aggregation of actin and cofilin in identical twins with juvenile‐onset dystonia
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The Williams syndrome: objective definition and diagnosis
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Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.
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A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease.
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The serine phosphatases PP1 and PP2A associate with and activate the actin‐binding protein cofilin in human T lymphocytes
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Dephosphorylation of Serine 3 Regulates Nuclear Translocation of Cofilin*
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The plasma and cytoplasmic forms of human gelsolin differ in disulfide structure.
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How molecular microscopy revealed new insights into the dynamics of hepatic endothelial fenestrae in the past decade
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Analysis of the interactions of actin depolymerizing factor with G- and F-actin.
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Nucleotide exchange between cytosolic ATP and F-actin-bound ADP may be a major energy-utilizing process in unstimulated platelets.
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Mechanism of K+-induced actin assembly
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Characterization of a novel cofilin isoform that is predominantly expressed in mammalian skeletal muscle.
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Neurodegenerative stimuli induce persistent ADF/cofilin–actin rods that disrupt distal neurite function
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α-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy
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Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells
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Analysis of Erythrocyte and Platelet Membrane Proteins in Various Forms of β-Thalassemia
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Actin Filament-Stabilizing Protein Tropomyosin Regulates the Size of Dendritic Fields
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Non-Muscle Cofilin Is a Component of Tubulobulbar Complexes in the Testis1
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Actin monomer binding proteins.
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Misakinolide A Is a Marine Macrolide That Caps but Does Not Sever Filamentous Actin*
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Cortactin signalling and dynamic actin networks.
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Gelsolin modulation in epithelial and stromal cells of mammary carcinoma.
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In vitro screening of crude extracts and pure metabolites obtained from marine invertebrates for the treatment of breast cancer
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Gelsolin superfamily proteins: key regulators of cellular functions
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Normal modes as refinement parameters for the F-actin model.
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Partial purification and characterization of an actin depolymerizing factor from brain
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The amino acid sequence of actin from chicken skeletal muscle actin and chicken gizzard smooth muscle actin
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Cytoskeletal Changes Regulated by the PAK4 Serine/Threonine Kinase Are Mediated by LIM Kinase 1 and Cofilin*
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Heterogeneity of nemaline myopathy cases with skeletal muscle α‐actin gene mutations
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Recent advances in understanding the cell death pathways activated by anticancer therapy
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Enhanced motility in NIH 3T3 fibroblasts that overexpress gelsolin.
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Purification, characterization and crystallization of human platelet profilin expressed in Escherichia coli.
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Citron-N is a neuronal Rho-associated protein involved in Golgi organization through actin cytoskeleton regulation
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Determining the differences in actin binding by human ADF and cofilin.
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Overexpression of profilin reduces the migration of invasive breast cancer cells.
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Kindler syndrome: a new mutation and new diagnostic possibilities.
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Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling.
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Phosphoinositides and membrane traffic in health and disease
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Muscle Z-band ultrastructure: titin Z-repeats and Z-band periodicities do not match.
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Liver autoimmune serology: a consensus statement from the committee for autoimmune serology of the International Autoimmune Hepatitis Group.
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The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration.
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Prothymosin α Interacts with Free Core Histones in the Nucleus of Dividing Cells
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Cyclase-associated protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells.
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Active ERK/MAP kinase is targeted to newly forming cell–matrix adhesions by integrin engagement and v‐Src
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Intracellular signaling pathways that regulate dendritic spine morphogenesis
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Specific requirement for two ADF/cofilin isoforms in distinct actin-dependent processes in Caenorhabditis elegans
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Filament Assembly from Profilin-Actin*
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Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression
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Actinin-4, a Novel Actin-bundling Protein Associated with Cell Motility and Cancer Invasion
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The motility of glioblastoma tumour cells is modulated by intracellular cofilin expression in a concentration-dependent manner.
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Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease.
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Postsynaptic actin and neuronal plasticity
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Role of nucleotide hydrolysis in the dynamics of actin filaments and microtubules.
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MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice, is mutated in autosomal dominant nonsyndromic hearing loss.
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Ezrin-Dependent Promotion of Glioma Cell Clonogenicity, Motility, and Invasion Mediated by BCL-2 and Transforming Growth Factor-β2
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The corneoscleral limbus in human corneal epithelial wound healing.
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The cell biology of neuronal navigation
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Affinity of alpha-actinin for actin determines the structure and mechanical properties of actin filament gels.
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Missense mutation in PAK3, R67C, causes X-linked nonspecific mental retardation.
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Cortactin Promotes Cell Motility by Enhancing Lamellipodial Persistence
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Two genes are responsible for Griscelli syndrome at the same 15q21 locus.
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Identification of cofilin, coronin, Rac and capZ in actin tails using a Listeria affinity approach.
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Replacement of ATP with ADP affects the dynamic and conformational properties of actin monomer.
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Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation.
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Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement
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Actopaxin Interacts with TESK1 to Regulate Cell Spreading on Fibronectin*
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Seizures induced by microperfusion of glutamate and glycine in the hippocampus of rats pretreated with latrunculin A
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Formins and VASPs may co-operate in the formation of filopodia.
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Spatial regulation of β-actin translation by Src-dependent phosphorylation of ZBP1
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Rho GTPases Regulate Axon Growth through Convergent and Divergent Signaling Pathways
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Cell migration: Rho GTPases lead the way.
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The gelsolin family of actin regulatory proteins: modular structures, versatile functions
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Environmental complexity and central nervous system development and function.
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Rapid Induction of Dendritic Spine Morphogenesis by trans-Synaptic EphrinB-EphB Receptor Activation of the Rho-GEF Kalirin
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Vaccinia virus motility.
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Cofilin Phosphorylation and Actin Reorganization Activities of Testicular Protein Kinase 2 and Its Predominant Expression in Testicular Sertoli Cells*
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12-fold difference between the critical monomer concentrations of the two ends of actin filaments in physiological salt conditions.
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Disoriented pathfinding by pioneer neurone growth cones deprived of filopodia by cytochalasin treatment
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Tropomyosin binding to F-actin protects the F-actin from disassembly by brain actin-depolymerizing factor (ADF).
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The role of the bound nucleotide in the polymerization of actin.
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Determination of the alpha-actinin-binding site on actin filaments by cryoelectron microscopy and image analysis
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A conformational change in the actin subunit can change the flexibility of the actin filament.
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Thymosin beta-4 expression is correlated with metastatic capacity of colorectal carcinomas.
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Frequency and significance of antibodies to actin in type 1 autoimmune hepatitis
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Downregulated gelsolin expression in hyperplastic and neoplastic lesions of the prostate
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Suppression of Tumorigenicity in Breast Cancer Cells by the Microfilament Protein Profilin 1
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The Yeast V159N Actin Mutant Reveals Roles for Actin Dynamics In Vivo
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A New Internal Mode in F-Actin Helps Explain the Remarkable Evolutionary Conservation of Actin's Sequence and Structure
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Actin's Actions in LTP-Induced Synapse Growth
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LIM Kinase 1 Activates cAMP-responsive Element-binding Protein during the Neuronal Differentiation of Immortalized Hippocampal Progenitor Cells*
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Nuclear localisation of the G-actin sequestering peptide thymosin β4
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Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
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Actin filament nucleation by the bacterial pathogen, Listeria monocytogenes
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High molecular weight microtubule-associated proteins bind to actin lattices (Hirano bodies)
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A Plasmodium actin-depolymerizing factor that binds exclusively to actin monomers.
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An α4 integrin–paxillin–Arf-GAP complex restricts Rac activation to the leading edge of migrating cells
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Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation.
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Specific features of neuronal size and shape are regulated by tropomyosin isoforms.
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Human diploid fibroblasts are resistant to MEK/ERK-mediated disruption of the actin cytoskeleton and invasiveness stimulated by Ras
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Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies.
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Structure, development, and plasticity of dendritic spines
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Overexpression of LIM Kinase 1 Renders Resistance to Apoptosis in PC12 Cells by Inhibition of Caspase Activation
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THE FINE STRUCTURE OF SOME INTRAGANGLIONIC ALTERATIONS
A. Hirano (1968)
A method for rapidly screening functionality of actin mutants and tagged actins
H. Rommelaere (2008)
Increase in Neurite Outgrowth Mediated by Overexpression of Actin Depolymerizing Factor
P. J. Meberg (2000)
Cofilin/ADF is required for cell motility during Drosophila ovary development and oogenesis
J. Chen (2001)
Cofilin takes the lead
V. Desmarais (2005)
Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics
A. Gohla (2005)
Further characterization of a conserved actin-binding 27-kDa fragment of actinogelin and alpha-actinins and mapping of their binding sites on the actin molecule by chemical cross-linking.
N. Mimura (1987)
Reversible induction of actin rods in mouse C3H-2K cells by incubation in salt buffers and by treatment with non-ionic detergents.
K. Iida (1986)
VEGF as a Key Mediator of Angiogenesis in Cancer
P. Carmeliet (2005)
Actin myopathy with nemaline bodies, intranuclear rods, and a heterozygous mutation in ACTA1 (Asp154Asn)
J. M. Schröder (2004)
Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain.
Nina Schumacher (2004)
Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells.
S. H. Chen (2003)
The essential role of profilin in the assembly of actin for microspike formation
S. Suetsugu (1998)
Nonrandom fusion of L‐Plastin(LCP1) and LAZ3(BCL6) genes by t(3;13)(q27;q14) chromosome translocation in two cases of B‐cell non‐Hodgkin lymphoma
S. Galiègue-Zouitina (1999)
Cation binding sites on actin: a structural relationship between antigenic epitopes and cation exchange.
C. Méjean (1988)
Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling
Y. Wang (1985)
A Family Demonstrating Inheritance of the Leach Phenotype: a Gerbich‐Negative Phenotype Associated with Elliptocytosis
G. Daniels (1986)
Fine structure of the Pick and Hirano bodies in a case of Pick's disease
S. Schochet (2004)
Cell migration during gastrulation.
R. Keller (2005)
Characterization of the activities of actin-affecting drugs on tumor cell migration.
C. Hayot (2006)
Prospectus: The road to autoimmune disease
N. Rose (2006)
Uncommon neurodegenerative causes of dementia.
A. Kurz (2005)
Congenital Fiber Type Disproportion—30 Years On
N. Clarke (2003)
Rac-WAVE2 signaling is involved in the invasive and metastatic phenotypes of murine melanoma cells
S. Kurisu (2005)
The actin cytoskeleton-associated protein zyxin acts as a tumor suppressor in Ewing tumor cells.
V. Amsellem (2005)
Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP‐dependent dendritogenesis
Si Tuen Lee-Hoeflich (2004)
Visualizing the Ca2+-dependent activation of gelsolin by using synchrotron footprinting
J. Kiselar (2003)
Usher I syndrome: unravelling the mechanisms that underlie the cohesion of the growing hair bundle in inner ear sensory cells
A. El-Amraoui (2005)
The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function
M. Egan (2003)
Chemotropic Responses of Retinal Growth Cones Mediated by Rapid Local Protein Synthesis and Degradation
D. S. Campbell (2001)
Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation.
J. Toshima (2001)
A monopartite nuclear localization sequence regulates nuclear targeting of the actin binding protein myopodin
Ariane de Ganck (2005)
PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans.
C. Nichols (2004)
Griscelli disease maps to chromosome 15q21 and is associated with mutations in the Myosin-Va gene
E. Pastural (1997)
Jasplakinolide's inhibition of the growth of prostate carcinoma cells in vitro with disruption of the actin cytoskeleton.
A. Senderowicz (1995)
Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity
A. Huttenlocher (1996)
Expression of transduced tropomyosin 1 cDNA suppresses neoplastic growth of cells transformed by the ras oncogene.
G. Prasad (1993)
Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer.
J. Welsh (2001)
Supravalvular aortic stenosis associated with a deletion disrupting the elastin gene.
A. K. Ewart (1994)
In vivo cell biology of cancer cells visualized with fluorescent proteins.
R. Hoffman (2005)
Mechanisms of Calcium Decay Kinetics in Hippocampal Spines: Role of Spine Calcium Pumps and Calcium Diffusion through the Spine Neck in Biochemical Compartmentalization
A. Majewska (2000)
Mutations in ACTN4, encoding α-actinin-4, cause familial focal segmental glomerulosclerosis
J. Kaplan (2000)
pH dependence of actin self-assembly.
F. Wang (1989)
Fine specificity and subclasses of IgG anti-actin autoantibodies differ in health and disease.
A. Zamanou (2003)
Alpha-actinin and myosin light chains in congenital nemaline myopathy.
C. Wallgren-Pettersson (1990)
Ankyrins and cellular targeting of diverse membrane proteins to physiological sites.
V. Bennett (2001)
Establishing cell polarity in development
A. Wodarz (2002)
Fascin, an actin-bundling protein expression in cervical neoplasms.
S. Kabukçuoğlu (2005)
Adenovirus mediated gelsolin gene therapy for orthotopic human bladder cancer in nude mice.
A. Sazawa (2002)
Cytoplasmic linker proteins promote microtubule rescue in vivo
Y. Komarova (2002)
Sertoli-Germ Cell Adherens Junction Dynamics in the Testis Are Regulated by RhoB GTPase via the ROCK/LIMK Signaling Pathway1
W. Lui (2003)
Signal-processing machines at the postsynaptic density.
M. Kennedy (2000)
Rho-associated Kinase ROCK Activates LIM-kinase 1 by Phosphorylation at Threonine 508 within the Activation Loop*
K. Ohashi (2000)
The Hallmarks of Cancer
D. Hanahan (2000)
Role of myosin VI in the differentiation of cochlear hair cells.
T. Self (1999)
Genome-wide screening for prognosis-predicting genes in early-stage non-small-cell lung cancer.
C. Müller-Tidow (2004)
BAG‐1 modulates the chaperone activity of Hsp70/Hsc70
S. Takayama (1997)
Effects of cytochalasin and phalloidin on actin
J. A. Cooper (1987)
Cofilin, a protein in porcine brain that binds to actin filaments and inhibits their interactions with myosin and tropomyosin.
E. Nishida (1984)
Specific organization of intracytoplasmic filaments in the dog testicular interstitial cell
T. Setoguti (2004)
The role of dynamin in the assembly and function of podosomes and invadopodia.
M. McNiven (2004)
Function and genetics of dystrophin and dystrophin-related proteins in muscle.
D. Blake (2002)
Microscopic Evidence That Actin-interacting Protein 1 Actively Disassembles Actin-depolymerizing Factor/Cofilin-bound Actin Filaments*
S. Ono (2004)
Structural studies of arthrin: monoubiquitinated actin.
S. Burgess (2004)
Coupling of Folding and Binding of Thymosin β4 upon Interaction with Monomeric Actin Monitored by Nuclear Magnetic Resonance*
M. Domanski (2004)
The calcium activation of gelsolin: insights from the 3A structure of the G4-G6/actin complex.
H. Choe (2002)
Overexpression of the thymosin β-10 gene in human ovarian cancer cells disrupts F-actin stress fiber and leads to apoptosis
S. Lee (2001)
Lessons from border cell migration in the Drosophila ovary: A role for myosin VI in dissemination of human ovarian cancer.
H. Yoshida (2004)
ADF/Cofilin Controls Cell Polarity during Fibroblast Migration
H. Dawe (2003)
Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile-X knockout mice.
S. Irwin (2002)
Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors
G. Raval (2003)
Apoptosis induced by interferon‐α and antagonized by EGF is regulated by caspase‐3‐mediated cleavage of gelsolin in human epidermoid cancer cells
M. Boccellino (2004)
LIM-kinase1 Hemizygosity Implicated in Impaired Visuospatial Constructive Cognition
J.Michael Frangiskakis (1996)
Pax and vertebrate development.
R. Wehr (1996)
Xenopus laevis actin-depolymerizing factor/cofilin: a phosphorylation- regulated protein essential for development
H. Abe (1996)
Regulation of the actin cytoskeleton by PIP2 in cytokinesis
M. Logan (2006)
Inhibition of invasiveness of human lung cancer cell line H1299 by over‐expression of cofilin
Yi-Jang Lee (2005)
An exonic mutation in the HuP2 paired domain gene causes Waardenburg's syndrome
C. Baldwin (1992)
Rho GTPases and activity-dependent dendrite development
L. Aelst (2004)
Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia – An in vivo study
N. Verrills (2006)
Immunohistochemical localization of C‐reactive protein‐binding sites in human atherosclerotic aortic lesions by a modified streptavidin‐biotin‐staining method
K. Hatanaka (1995)
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia
S. Kitajiri (2004)
Cell migration at a glance
M. Vicente-Manzanares (2005)
Expression of profilin, an actin-binding protein, in rat experimental glomerulonephritis and its upregulation by basic fibroblast growth factor in cultured rat mesangial cells.
M. Tamura (2000)
Involvement of Cytoskeletal Components in BK Virus Infectious Entry
S. Eash (2005)
Actin- and microtubule-dependent organelle motors: interrelationships between the two motility systems.
G. Langford (1995)
Myopodin, a synaptopodin homologue, is frequently deleted in invasive prostate cancers.
F. Lin (2001)
Identification and Testing of a Gene Expression Signature of Invasive Carcinoma Cells within Primary Mammary Tumors
W. Wang (2004)
Regulation of cell migration and survival by focal adhesion targeting of Lasp-1
Y. H. Lin (2004)
Actin-ATP Hydrolysis Is a Major Energy Drain for Neurons
B. W. Bernstein (2003)
Cloning of drebrin A and induction of neurite-like processes in drebrin-transfected cells.
T. Shirao (1992)
Role of Cofilin in Epidermal Growth Factor–Stimulated Actin Polymerization and Lamellipod Protrusion
A. Chan (2000)
Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons.
B. W. Bernstein (2006)
αvβ3 integrin and cofilin modulate K1735 melanoma cell invasion
D. Dang (2006)
Nuclear actin extends, with no contraction in sight.
T. Pederson (2005)
Stretch of the Vascular Wall Induces Smooth Muscle Differentiation by Promoting Actin Polymerization*
S. Albinsson (2004)
Domain motions in actin.
R. Page (1998)
The role of Pax3 and Pax7 in development and cancer.
A. Mansouri (1998)
Mutations of ESPN cause autosomal recessive deafness and vestibular dysfunction
S. Naz (2004)
Characterization of a beta-actin mRNA zipcode-binding protein.
A. Ross (1997)
Essential functions and actin‐binding surfaces of yeast cofilin revealed by systematic mutagenesis
P. Lappalainen (1997)
Structural Features of LIM Kinase That Control Effects on the Actin Cytoskeleton*
D. Edwards (1999)
Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose
L. Machesky (1994)
Cytoskeletal dissociation of ezrin during renal anoxia: role in microvillar injury.
J. Chen (1994)
Lateral motion of fluorescently labeled acetylcholine receptors in membranes of developing muscle fibers.
D. Axelrod (1976)
Actin is the naturally occurring inhibitor of deoxyribonuclease I.
E. Lazarides (1974)
THE SMALL PYRAMIDAL NEURON OF THE RAT CEREBRAL CORTEX
A. Peters (2004)
Gelsolin Deficiency Blocks Podosome Assembly and Produces Increased Bone Mass and Strength
M. Chellaiah (2000)
An αtropomyosin mutation alters dimer preference in nemaline myopathy
Mark A. Corbett (2005)
Influence of the bound nucleotide on the molecular dynamics of actin.
G. Hegyi (1988)
Opposite effects of cofilin and profilin from porcine brain on rate of exchange of actin-bound adenosine 5'-triphosphate.
E. Nishida (1985)
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
D. Hanahan (1996)
A comparative structural analysis of the ADF/Cofilin family
G. D. Bowman (2000)
Xenopus Actin-interacting Protein 1 (XAip1) Enhances Cofilin Fragmentation of Filaments by Capping Filament Ends*
K. Okada (2002)
X‐linked mild non‐syndromic mental retardation with neuropsychiatric problems and the missense mutation A365E in PAK3
A. Gedeon (2003)
Refinement of the F-actin model against X-ray fiber diffraction data by the use of a directed mutation algorithm.
M. Lorenz (1993)
Atomic model of the actin filament
K. Holmes (1990)
Actin cytoskeleton regulates extracellular matrix-dependent survival signals in glomerular epithelial cells.
K. Bijian (2005)
Actin and hnRNP U cooperate for productive transcription by RNA polymerase II
A. Kukalev (2005)
Control of Actin Reorganization by Slingshot, a Family of Phosphatases that Dephosphorylate ADF/Cofilin
R. Niwa (2002)
Expression of a nonpolymerizable actin mutant in Sf9 cells.
P. Joel (2004)
Prognostic significance of micrometastasis in non-small-cell lung cancer.
M. Coello (2004)
Rho and Rac Take Center Stage
K. Burridge (2004)
Phosphoinositide regulation of the actin cytoskeleton.
H. Yin (2003)
Structural basis of long-term potentiation in single dendritic spines
Masanori Matsuzaki (2004)
Associative Learning Elicits the Formation of Multiple-Synapse Boutons
Y. Geinisman (2001)
The human LASP1 gene is fused to MLL in an acute myeloid leukemia with t(11;17)(q23;q21)
S. Strehl (2003)
Equus caballus gelsolin--cDNA sequence and protein structural implications.
E. Koepf (1998)
Vinculin acts as a sensor in lipid regulation of adhesion-site turnover
I. Chandrasekar (2005)
Kinetic Analysis of the Interaction of Actin-depolymerizing Factor (ADF)/Cofilin with G- and F-Actins
F. Ressad (1998)
Specific Isoforms of Actin-binding Proteins on Distinct Populations of Golgi-derived Vesicles*
K. Heimann (1999)
Parsing the Polarity Code
I. Macara (2004)
Myosin VIIa Participates in Opsin Transport through The Photoreceptor Cilium
X. Liu (1999)
Widespread loss of gelsolin in breast cancers of humans, mice, and rats.
H. Asch (1996)
BCR/ABL induces multiple abnormalities of cytoskeletal function.
R. Salgia (1997)
Amino acid sequence of starfish oocyte depactin.
T. Takagi (1988)
Corn1: a mouse model for corneal surface disease and neovascularization.
R. S. Smith (1996)
Amyloid beta amyloidosis in Alzheimer's disease.
D. Price (1995)
Classification of dystonia.
S. Fahn (1998)
Nonmuscle myosin heavy-chain gene MYH14 is expressed in cochlea and mutated in patients affected by autosomal dominant hearing impairment (DFNA4).
F. Donaudy (2004)
Snyaptic and dendritic development and mental defect.
P. Huttenlocher (1975)
Pax: a murine multigene family of paired box-containing genes.
C. Walther (1991)
Regulation of substrate adhesion dynamics during cell motility.
I. Kaverina (2002)
α-Actinin-4-Mediated FSGS: An Inherited Kidney Disease Caused by an Aggregated and Rapidly Degraded Cytoskeletal Protein
J. Yao (2004)
Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective
R. Tanzi (2005)
Actin‐based motility of pathogens: the Arp2/3 complex is a central player
P. Cossart (2000)
Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein
A. Wada (1998)
Structural basis of actin sequestration by thymosin‐β4: implications for WH2 proteins
Edward Irobi (2004)
Gelsolin‐induced epithelial cell invasion is dependent on Ras–Rac signaling
V. De Corte (2002)
Actin in transcription
Neus Visa (2005)
Effect of Mutational Inactivation of Tyrosine Kinase Activity on BCR/ABL-Induced Abnormalities in Cell Growth and Adhesion in Human Hematopoietic Progenitors
P. Ramaraj (2004)
A quantitative analysis of G-actin binding proteins and the G-actin pool in developing chick brain
N. Devineni (1999)
Role of Proteins of the Ena/VASP Family in Actin-based Motility of Listeria monocytogenes
V. Laurent (1999)
Reconstitution of actin-based motility of Listeria and Shigella using pure proteins
T. Loisel (1999)
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Peng Li (1997)
A novel transcript encoding truncated LIM kinase 2 is specifically expressed in male germ cells undergoing meiosis.
H. Takahashi (1998)
The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.
C. Pugh (2003)
Thymosin beta-15 predicts for distant failure in patients with clinically localized prostate cancer-results from a pilot study.
A. Chakravatri (2000)
Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly
X. Chen (2006)
Actin-Based Motility of Intracellular Microbial Pathogens
M. Goldberg (2001)
Modular organization of actin crosslinking proteins.
Paul Matsudalra (1991)
Identification of Proteins in the Postsynaptic Density Fraction by Mass Spectrometry
R. Walikonis (2000)
Regulation of actin synthesis in rat hepatocytes by cytoskeletal rearrangements.
K. H. Reuner (1996)
A Role for Phospholipase C-γ-mediated Signaling in Tumor Cell Invasion
J. Kassis (1999)
The Molecular Signature of Metastases of Human Hepatocellular Carcinoma
A. Budhu (2005)
Binding proteins for mRNA localization and local translation, and their dysfunction in genetic neurological disease
G. Bassell (2004)
B-Raf Acts via the ROCKII/LIMK/Cofilin Pathway To Maintain Actin Stress Fibers in Fibroblasts
C. Pritchard (2004)
Kinetics of the cooperative association of actin to actin filaments.
A. Wegner (1975)
cDNA cloning and sequence of a new type of actin in mouse B16 melanoma.
H. Sadano (1988)
Differential Regulation of Actin Depolymerizing Factor and Cofilin in Response to Alterations in the Actin Monomer Pool*
L. Minamide (1997)
Prognostic meta-signature of breast cancer developed by two-stage mixture modeling of microarray data
R. Shen (2004)
Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome.
D. Siegel (2003)
Regulation of immunity by self-reactive T cells
M. Kronenberg (2005)
The tripartite motif family identifies cell compartments
A. Reymond (2001)
Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis.
M. Tamura (1996)
Tropomyosin isoforms from the γ gene differing at the C‐terminus are spatially and developmentally regulated in the brain
Bernadette Vrhovski (2003)
Polymerization of actin: mechanism of the Mg2+-induced process at pH 8 and 20 degrees C.
Carl Frieden (1983)
Interneuron deficits in patients with the Miller-Dieker syndrome
Maclean M Pancoast (2004)
Regulation of actin dynamics is critical for endothelial barrier functions.
J. Waschke (2005)
Prognostic significance of gelsolin expression level and variability in non-small cell lung cancer.
J. Yang (2004)
Decreased expression of the seven ARP2/3 complex genes in human gastric cancers.
A. Kaneda (2004)
Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells.
P. Hotulainen (2005)
Cofilin Promotes Actin Polymerization and Defines the Direction of Cell Motility
Mousumi Ghosh (2004)
AIP1/WDR1 supports mitotic cell rounding.
Taketsugu Fujibuchi (2005)
Tumor cells caught in the act of invading: their strategy for enhanced cell motility.
W. Wang (2005)
T-cell costimulatory molecules: optimal targets for the treatment of allergic airway disease with monoclonal antibodies.
R. Kroczek (2005)
Tropomyosin isoform diversity and neuronal morphogenesis
C. Dufour (1998)
New anti‐actin drugs in the study of the organization and function of the actin cytoskeleton
I. Spector (1999)
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
A. Goate (1991)
Proteome analysis of hepatocellular carcinoma cell strains, MHCC97‐H and MHCC97‐L, with different metastasis potentials
Shijian Ding (2004)
Interaction of G-actin with thymosin β4 and its variants thymosin β9 and thymosin β9met
Catherine Jean (2004)
Binding of Divalent Cation and Nucleotide to G-actin in the Presence of Profilin (*)
I. Perelroizen (1995)
Thymosin β4 and a synthetic peptide containing its actin‐binding domain promote dermal wound repair in db/db diabetic mice and in aged mice
D. Philp (2003)
Formin Is a Processive Motor that Requires Profilin to Accelerate Actin Assembly and Associated ATP Hydrolysis
S. Romero (2004)
Prespecification and plasticity: shifting mechanisms of cell migration.
P. Friedl (2004)
p21-activated Kinase Links Rac/Cdc42 Signaling to Merlin*
G. Xiao (2002)
Micrometastasis in breast cancer and other solid tumors.
K. Pantel (2004)
Role of Thymosin β4 in Tumor Metastasis and Angiogenesis
Hee-Jae Cha (2003)
Small-molecule inhibitors of actin dynamics and cell motility.
Gabriel Fenteany (2003)
The war on cancer
M. Sporn (1996)
In vitro expression analysis shows that the secretory form of gelsolin is the sole source of amyloid in gelsolin-related amyloidosis.
H. Kangas (1996)
Quantitative Cancer Proteomics: Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) as a Tool for Prostate Cancer Research*S
Patrick A Everley (2004)
Cofilin‐2, a novel type of cofilin, is expressed specifically at aggregation stage of Dictyostelium discoideum development
H. Aizawa (2001)
Identification, Characterization, and Intracellular Distribution of Cofilin in Dictyostelium discoideum(*)
H. Aizawa (1995)
Molecular requirements for epithelial-mesenchymal transition during tumor progression.
M. Huber (2005)
Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease
G. Stokin (2005)
WDR1 colocalizes with ADF and actin in the normal and noise‐damaged chick cochlea
S. Oh (2002)
Epigenetic regulation of gelsolin expression in human breast cancer cells.
L. M. Mielnicki (1999)
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
Neng Yang (1998)
Y. Gillerot (1983)
The modular structure of actin-regulatory proteins.
Y. Puius (1998)
On the trail of genetic culprits in Williams syndrome.
M. Keating (1997)
Evidence that actin and myosin are involved in the poleward flux of tubulin in metaphase kinetochore microtubules of crane-fly spermatocytes.
R. Silverman-Gavrila (2000)
Colocalization of ADF and cofilin in intranuclear actin rods of cultured muscle cells
S. Ono (2004)
Familial hypertrophic cardiomyopathy: from mutations to functional defects.
G. Bonne (1998)
Foot and mouth: podosomes, invadopodia and circular dorsal ruffles
R. Buccione (2004)
Clinical course correlates poorly with muscle pathology in nemaline myopathy
M. Ryan (2003)
Supravalvular Aortic Stenosis
J. C. Williams (1961)
Cohort migration of carcinoma cells: differentiated colorectal carcinoma cells move as coherent cell clusters or sheets.
K. Nabeshima (1999)
Hirano Body Filaments Contain Actin and Actin‐Associated Proteins
P. Galloway (1987)
Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins.
A. Gambhir (2004)
Smooth muscle autoantibodies and autoantigens.
B. H. Toh (1979)
Dendritic spines of rat cerebellar Purkinje cells: serial electron microscopy with reference to their biophysical characteristics
K. Harris (1988)
Detection of a sequence involved in actin-binding and phosphoinositide-binding in the N-terminal side of cofilin
K. Kusano (2004)
The oculocerebrorenal syndrome gene product is a 105-kD protein localized to the Golgi complex.
I. Olivos-Glander (1995)
Homozygosity for a nonsense mutation in the alpha-tropomyosin gene TPM3 in a patient with severe nemaline myopathy
P. Tan (1997)
Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein.
D. Stewart (1999)
Calcium from internal stores modifies dendritic spine shape.
K. Harris (1999)
Relationship of admission plasma gelsolin levels to clinical outcomes in patients after major trauma.
K. Mounzer (1999)
Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I
D. Drubin (1990)
An actin-interacting heptapeptide in the cofilin sequence.
N. Yonezawa (1989)
The Caenorhabditis elegans unc-60 gene encodes proteins homologous to a family of actin-binding proteins
K. McKim (2004)
Domain motion in actin observed by fluorescence resonance energy transfer.
M. Miki (1994)
The KKRKK sequence is involved in heat shock-induced nuclear translocation of the 18-kDa actin-binding protein, cofilin.
K. Iida (1992)
The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase C.
P. Goldschmidt-Clermont (1990)
Anticytoskeletal autoantibodies in the connective tissue diseases.
J. Senécal (1985)
An actin-depolymerizing protein (depactin) from starfish oocytes: properties and interaction with actin
I. Mabuchi (1983)
Head to tail polymerization of actin.
A. Wegner (1976)
Molecular details of formin-mediated actin assembly.
D. Kovar (2006)
Cofilin increases the torsional flexibility and dynamics of actin filaments.
E. Próchniewicz (2005)
Phosphorylation of Adf/Cofilin Abolishes Egf-Induced Actin Nucleation at the Leading Edge and Subsequent Lamellipod Extension
N. Zebda (2000)
Novel actin cytoskeleton: actin tubules.
M. Sameshima (2000)
Failure of gelsolin overexpression to regulate lymphocyte apoptosis.
S. C. Posey (2000)
p140mDia, a mammalian homolog of Drosophila diaphanous,is a target protein for Rho small GTPase and is a ligand for profilin
N. Watanabe (1997)
Inhibition of apoptosis by the actin‐regulatory protein gelsolin
M. Ohtsu (1997)
Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein
D. Gibbs (2003)
Axonal Protein Synthesis and Degradation Are Necessary for Efficient Growth Cone Regeneration
Poonam Verma (2005)
Beginning and ending an actin filament: control at the barbed end.
S. Zigmond (2004)
Ca2+ regulation of gelsolin activity: binding and severing of F-actin.
H. J. Kinosian (1998)
Complete amino acid sequences and phosphorylation sites, determined by Edman degradation and mass spectrometry, of rat parotid destrin- and cofilin-like proteins.
T. Kanamori (1998)
A role for cofilin and LIM kinase in Listeria-induced phagocytosis
H. Bierne (2001)
Friends or foes — bipolar effects of the tumour stroma in cancer
M. Mueller (2004)
Thymosin β15 expression in tumor cell lines with varying metastatic potential
L. Bao (2004)
Expression of transfected mutant beta-actin genes: transitions toward the stable tumorigenic state.
J. Leavitt (1987)
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
I. Vivanco (2002)
Dephosphorylation of cofilin accompanies heat shock-induced nuclear accumulation of cofilin.
Y. Ohta (1989)
Involvement of Slingshot in the Rho-mediated Dephosphorylation of ADF/Cofilin during Xenopus Cleavage
K. Tanaka (2005)
Caspase-3-induced gelsolin fragmentation contributes to actin cytoskeletal collapse, nucleolysis, and apoptosis of vascular smooth muscle cells exposed to proinflammatory cytokines.
Y. Geng (1998)
Gene expression correlates of clinical prostate cancer behavior.
Dinesh K Singh (2002)
Three novel brain tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene through the use of alternative promoters and alternative RNA processing.
J. P. Lees-Miller (1990)
Intracellular Localization of Tropomyosin mRNA and Protein Is Associated with Development of Neuronal Polarity
A. J. Hannan (1995)
Activation of Phospholipase C-γ by Phosphatidylinositol 3,4,5-Trisphosphate*
Y. S. Bae (1998)
Thymosin β4 Accelerates Wound Healing
K. M. Malinda (1999)
Regulation of the Cortical Actin Cytoskeleton in Budding Yeast by Twinfilin, a Ubiquitous Actin Monomer-sequestering Protein
B. Goode (1998)
Overexpression of EMS1/cortactin in NIH3T3 fibroblasts causes increased cell motility and invasion in vitro
A. S. Patel (1998)
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