Regulation Of Thyroid Hormone Production And Measurement Of Thyrotropin
Published 2010 · Medicine
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The hypothalamic-pituitary axis regulates the production of thyroid hormones so that the serum concentrations of thyroxine (T4) and triiodothyronine (T3) remain in a narrow range in the euthyroid state. These hormones have essential roles in growth; development; metabolism of carbohydrate, fat, and proteins; and adaptation to the environment. This chapter will focus on the production of thyroid hormones, hypothalamic-pituitary control of the thyroid, and the use of serum thyrotropin (thyroid stimulating hormone, TSH) measurements for evaluation of thyroid function.
This paper references
Free triiodothyronine has a distinct circadian rhythm that is delayed but parallels thyrotropin levels.
W. Russell (2008)
The occurrence of mono- and di-iodotyrosine in the blood of a patient with congenital goiter.
J. Stanbury (1955)
Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin.
K. Spiegel (2004)
J. Morley (1980)
Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III).
J. Hollowell (2002)
Identification of cyclic adenosine 3',5'-monophosphate response element modulator as an activator of the human sodium/iodide symporter upstream enhancer.
M. Fenton (2008)
Pendred's syndrome: identification of the genetic defect a century after its recognition.
P. Kopp (1999)
Effect of normal and reversed sleep-wake cycles upon nyctohemeral rhythmicity of plasma thyrotropin: evidence suggestive of an inhibitory influence in sleep.
Donal C. Parker (1976)
Narrow individual variations in serum T(4) and T(3) in normal subjects: a clue to the understanding of subclinical thyroid disease.
S. Andersen (2002)
Update on intrathyroidal iodine metabolism.
J. T. Dunn (2001)
The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance.
O. Dohán (2003)
Linear modulation of serum thyrotrophin by thyroid hormone treatment in hypothyroidism.
A. Pekary (1980)
TSH Receptor Mutations and Thyroid Disease
L. Duprez (1998)
The molecular biology of thyroid peroxidase: cloning, expression and role as autoantigen in autoimmune thyroid disease.
S. Mclachlan (1992)
The importance of iodine nutrition during pregnancy.
D. Glinoer (2007)
Effect of cold exposure on serum thyrotropin.
J. Hershman (1970)
Immunoassay of endogenous plasma insulin in man.
R. Yalow (1960)
THE BIOASSAY OF THYROTROPIN IN SERUM1
J. Mckenzie (1958)
Control of thyrotropin secretion in man.
J. Hershman (1971)
The effect of stressful diagnostic studies and surgery on anterior pituitary hormone release in man.
J. Sowers (1977)
Urinary iodine concentration: United States National Health And Nutrition Examination Survey 2001-2002.
K. Caldwell (2005)
Molecular analysis of mutated thyroid peroxidase detected in patients with total iodide organification defects.
H. Bikker (1997)
A sensitive and precise radioimmunoassay for human thyroid-stimulating hormone.
A. Pekary (1975)
Age-specific distribution of serum thyrotropin and antithyroid antibodies in the US population: implications for the prevalence of subclinical hypothyroidism.
M. Surks (2007)
Serum thyrotropin and thyroid hormone levels in elderly and middle-aged euthyroid persons.
J. Hershman (1993)
Impairment of hypothalamic-pituitary-thyroid function in rats treated with human recombinant tumor necrosis factor-alpha (cachectin).
X. Pang (1989)
Factitious elevation of thyrotropin in a new ultrasensitive assay: implications for the use of monoclonal antibodies in "sandwich" immunoassay.
B. B. Kahn (1988)
A new monoclonal-antibody two-site solid-phase immunoradiometric assay for human thyrotropin evaluated.
A. Pekary (1984)
Dietary iodine in pregnant women from the Boston, Massachusetts area.
E. N. Pearce (2004)
Utility of the radioimmunoassay of serum thyrotrophin in man.
J. Hershman (1971)
Thyrotropin levels in a population with no clinical, autoantibody, or ultrasonographic evidence of thyroid disease: implications for the diagnosis of subclinical hypothyroidism.
T. E. Hamilton (2008)
Patterns off recovery of the hypothalamic-pituitary-thyroid axis in patients taken of chronic thyroid therapy.
L. Krugman (1975)
Central hypothyroidism associated with retinoid X receptor-selective ligands.
S. Sherman (1999)
A novel homozygous missense mutation of the dual oxidase 2 (DUOX2) gene in an adult patient with large goiter.
H. Ohye (2008)
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