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Actin And Diseases Of The Nervous System
B. W. Bernstein, M. Maloney, J. Bamburg
Published 2011 · Biology
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Abnormal regulation of the actin cytoskeleton results in several pathological conditions affecting primarily the nervous system. Those of genetic origin arise during development, but others manifest later in life. Actin regulation is also affected profoundly by environmental factors that can have sustained consequences for the nervous system. Those consequences follow from the fact that the actin cytoskeleton is essential for a multitude of cell biological functions ranging from neuronal migration in cortical development and dendritic spine formation to NMDA receptor activity in learning and alcoholism. Improper regulation of actin, causing aggregation, can contribute to the neurodegeneration of amyloidopathies, such as Down’s syndrome and Alzheimer’s disease. Much progress has been made in understanding the molecular basis of these diseases.
This paper references
The Dynamics of Dendritic Structure in Developing Hippocampal Slices
M. Dailey (1996)
Intranuclear actin bundles induced by dimethyl sulfoxide in interphase nucleus of Dictyostelium
Y. Fukui (1978)
Cofilin expression induces cofilin-actin rod formation and disrupts synaptic structure and function in Aplysia synapses.
Dong-Hyuk Jang (2005)
Dendritic Spine "Dysgenesis" and Mental Retardation
D. Purpura (1974)
Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1
M. Innocenti (2003)
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
E. Roberson (2007)
Storage of Spatial Information by the Maintenance Mechanism of LTP
Eva Pastalkova (2006)
A Role of Actin Filament in Synaptic Transmission and Long-Term Potentiation
C. H. Kim (1999)
Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons.
B. W. Bernstein (2006)
Actin-ATP Hydrolysis Is a Major Energy Drain for Neurons
B. W. Bernstein (2003)
Uncommon neurodegenerative causes of dementia.
A. Kurz (2005)
Actin disassembles reversibly during electrically induced recycling of synaptic vesicles in cultured neurons.
B. W. Bernstein (1998)
Morphogen signaling at the vertebrate growth cone: a few cases or a general strategy?
P. Bovolenta (2005)
Rho proteins, mental retardation and the cellular basis of cognition
G. Ramakers (2002)
INTRACYTOPLASMIC ROD‐LIKE INCLUSIONS IN CAUDATE NUCLEUS
N. Kawano (1981)
Direct Measurement of Coupling Between Dendritic Spines and Shafts
K. Svoboda (1996)
Organization and translation of mRNA in sympathetic axons
Sunkyung Lee (2003)
Unusual, rod-shaped cytoplasmic inclusions (Hirano bodies) in a cerebellar hemangioblastoma
Yao-Shi Fu (2004)
Cofilin-mediated neurodegeneration in alzheimer’s disease and other amyloidopathies
M. Maloney (2007)
Effects of secreted oligomers of amyloid β‐protein on hippocampal synaptic plasticity: a potent role for trimers
M. Townsend (2006)
LIM Kinase 1 Coordinates Microtubule Stability and Actin Polymerization in Human Endothelial Cells*
M. Gorovoy (2005)
F. Goodwin (1990)
Rod-shaped filamentous inclusions and other ultrastructural features in a cerebellar astrocytoma
E. Gessaga (2004)
Spatial regulation of β-actin translation by Src-dependent phosphorylation of ZBP1
S. Hüttelmaier (2005)
Bridging cognition, the brain and molecular genetics: evidence from Williams syndrome
U. Bellugi (1999)
Familial clustering of the ataxic form of Creutzfeldt-Jakob disease with Hirano bodies.
L. Cartier (1985)
Microtubule “Plus-End-Tracking Proteins” The End Is Just the Beginning
S. Schuyler (2001)
Mapping cofilin-actin rods in stressed hippocampal slices and the role of cdc42 in amyloid-beta-induced rods.
R. C. Davis (2009)
Smn, the spinal muscular atrophy–determining gene product, modulates axon growth and localization of β-actin mRNA in growth cones of motoneurons
W. Rossoll (2003)
SUPERNUMERARY RIBS IN DEVELOPMENTAL TOXICITY BIOASSAYS AND IN HUMAN POPULATIONS: INCIDENCE AND BIOLOGICAL SIGNIFICANCE
N. Chernoff (2004)
BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin
Zhexing Wen (2007)
Structure and function of dendritic spines.
E. Nimchinsky (2002)
Mutation in Filamin A Causes Periventricular Heterotopia, Developmental Regression, and West Syndrome in Males
Marcelo R. Masruha (2006)
Direct stimulation of receptor‐controlled phospholipase D1 by phospho‐cofilin
L. Han (2007)
Acute actions of marine toxin latrunculin A on the electrophysiological properties of cultured dorsal root ganglion neurones.
Wael E Houssen (2006)
Presynaptic Contributions of Chordin to Hippocampal Plasticity and Spatial Learning
M. Sun (2007)
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2
S. F. Tavazoie (2005)
On dendrites in Down syndrome and DS murine models: a spiny way to learn
R. Benavides-Piccione (2004)
Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia
G. Corfas (2004)
An essential role for cortactin in the modulation of the potassium channel Kv1.2
M. R. Williams (2007)
Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulation.
K. Shen (1999)
Axonal Protein Synthesis and Degradation Are Necessary for Efficient Growth Cone Regeneration
Poonam Verma (2005)
Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice
Mansuo L. Hayashi (2007)
Ultrastructure of Hirano bodies
M. Tomonaga (2004)
Transient and Persistent Dendritic Spines in the Neocortex In Vivo
A. Holtmaat (2005)
Fine structure of the Pick and Hirano bodies in a case of Pick's disease
S. Schochet (2004)
Regulation of NMDA Receptors by Neuregulin Signaling in Prefrontal Cortex
Zhenglin Gu (2005)
Actin polymerization serves as a membrane domain switch in model lipid bilayers.
A. Liu (2006)
The Williams syndrome: objective definition and diagnosis
M. Preus (1984)
Amyloid beta amyloidosis in Alzheimer's disease.
D. Price (1995)
Calcium from internal stores modifies dendritic spine shape.
K. Harris (1999)
Signaling from MARK to Tau: Regulation, Cytoskeletal Crosstalk, and Pathological Phosphorylation
T. Timm (2006)
Tolcapone: COMT inhibition for the treatment of Parkinson's disease.
S. Fahn (1998)
Formation of Hirano bodies in Dictyostelium and mammalian cells induced by expression of a modified form of an actin-crosslinking protein.
Andrew Maselli (2002)
THE SMALL PYRAMIDAL NEURON OF THE RAT CEREBRAL CORTEX
A. Peters (2004)
Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function
J. Darnell (2001)
Serum cholesterol changes after midlife and late-life cognition
A. Solomon (2007)
Actin' together: serum response factor, its cofactors and the link to signal transduction.
G. Posern (2006)
Mitochondrial translocation of cofilin is an early step in apoptosis induction
B. T. Chua (2003)
N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex.
G. C. Bellenchi (2007)
The effect of cellular cholesterol on membrane-cytoskeleton adhesion
M. Sun (2007)
Filopodia, Spines, and the Generation of Synaptic Diversity
J. Jontes (2000)
Transient decrease in F‐actin may be necessary for translocation of proteins into dendritic spines
Y. Ouyang (2005)
Transmembrane Neuregulins Interact with LIM Kinase 1, a Cytoplasmic Protein Kinase Implicated in Development of Visuospatial Cognition*
J. Wang (1998)
An electron-microscopic study of scrapie in the rat: further observations on "inclusion bodies" and virus-like particles.
E. J. Field (1972)
The physiological significance of β-actin mRNA localization in determining cell polarity and directional motility
E. Shestakova (2001)
Secreted cell signaling molecules in axon guidance
S. Yoshikawa (2004)
Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
M. Ankarcrona (1995)
Role of the β‐amyloid protein in Alzheimer's disease
S. Sisodia (1995)
Hirano bodies and related neuronal inclusions
A. Hirano (1994)
Evidence That Long-Term Potentiation Occurs within Individual Hippocampal Synapses during Learning
V. Fedulov (2007)
LIM Kinase 1 Activates cAMP-responsive Element-binding Protein during the Neuronal Differentiation of Immortalized Hippocampal Progenitor Cells*
E. J. Yang (2004)
Molecular functions of nuclear actin in transcription
P. Percipalle (2006)
Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease.
T. Suzuki (2000)
The role of cholesterol in the biosynthesis of β-amyloid.
E. Frears (1999)
Natural oligomers of the amyloid-β protein specifically disrupt cognitive function
J. Cleary (2005)
Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses
W. Morishita (2005)
Environmental complexity and central nervous system development and function.
M. Lewis (2004)
Histological Changes induced in Sympathetic, Motor, and Sensory Nerve Cells by Functional Activity (Preliminary note).
G. Mann (1894)
Pathways towards and away from Alzheimer's disease
M. Mattson (2004)
The cytoskeleton and cell signaling: component localization and mechanical coupling.
P. Janmey (1998)
LIM-kinase1 Hemizygosity Implicated in Impaired Visuospatial Constructive Cognition
J.Michael Frangiskakis (1996)
Actin-based plasticity in dendritic spines.
A. Matus (2000)
Nuclear Actin Regulates Dynamic Subcellular Localization and Activity of the SRF Cofactor MAL
M. Vartiainen (2007)
Chemotropic Responses of Retinal Growth Cones Mediated by Rapid Local Protein Synthesis and Degradation
D. S. Campbell (2001)
Tropomyosin and ADF/cofilin as collaborators and competitors.
T. Kuhn (2008)
Actin's Actions in LTP-Induced Synapse Growth
J. Lisman (2003)
Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice
C. Hoogenraad (2002)
Nuclear DNA helicase II (RNA helicase A) binds to an F-actin containing shell that surrounds the nucleolus.
S. Zhang (2004)
Dendritic development and mental defect.
P. Huttenlocher (1970)
Cocaine Increases Actin Cycling: Effects in the Reinstatement Model of Drug Seeking
S. Toda (2006)
The Slingshot Family of Phosphatases Mediates Rac1 Regulation of Cofilin Phosphorylation, Laminin-332 Organization, and Motility Behavior of Keratinocytes*
K. Kligys (2007)
Dendritic spine abnormalities in the occipital cortex of C57BL/6 Fmr1 knockout mice
B. C. McKinney (2005)
Meige syndrome: Neuropathology of a case
J. Kulisevsky (1988)
Increased Ethanol Resistance and Consumption in Eps8 Knockout Mice Correlates with Altered Actin Dynamics
N. Offenhäuser (2006)
Regulation of ADF/cofilin phosphorylation and synaptic function by LIM-kinase
Yanghong Meng (2004)
Correlates of life stress in an alcohol treatment sample.
J. Mcquaid (2000)
Mechanism of actin filament turnover by severing and nucleation at different concentrations of ADF/cofilin.
E. Andrianantoandro (2006)
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
A. Goate (1991)
Regulation of Spine Calcium Dynamics by Rapid Spine Motility
A. Majewska (2000)
Functional, structural, and metabolic abnormalities of the hippocampal formation in Williams syndrome.
A. Meyer-Lindenberg (2005)
Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules
Xinnan Wang (2007)
FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.
M. Castets (2005)
Nap1-Regulated Neuronal Cytoskeletal Dynamics Is Essential for the Final Differentiation of Neurons in Cerebral Cortex
Yukako Yokota (2007)
Destruction of microfilament bundles in mouse embryo fibroblasts treated with inhibitors of energy metabolism.
A. Bershadsky (1980)
Neuropathological changes of the brain in myotonic dystrophy - some new observations
S. Ono (1987)
Control of Actin Reorganization by Slingshot, a Family of Phosphatases that Dephosphorylate ADF/Cofilin
R. Niwa (2002)
Cytoplasmic inclusion bodies within neurons of the thalamus in myotonic dystrophy. A light and electron microscope study.
A. Culebras (1973)
Hirano bodies and chronic alcoholism
R. Laas (1994)
Integration of biochemical signalling in spines
M. Kennedy (2005)
On the trail of genetic culprits in Williams syndrome.
M. Keating (1997)
Shrinkage of Dendritic Spines Associated with Long-Term Depression of Hippocampal Synapses
Q. Zhou (2004)
Lateral motion of fluorescently labeled acetylcholine receptors in membranes of developing muscle fibers.
D. Axelrod (1976)
Caspase cleavage of the amyloid precursor protein modulates amyloid β‐protein toxicity
D. Lu (2003)
Induction of Spine Growth and Synapse Formation by Regulation of the Spine Actin Cytoskeleton
K. Zito (2004)
Aggregation of actin and cofilin in identical twins with juvenile‐onset dystonia
M. Gearing (2002)
The behavioural and motor consequences of focal lesions of the basal ganglia in man.
K. Bhatia (1994)
Human CAP1 is a key factor in the recycling of cofilin and actin for rapid actin turnover.
K. Moriyama (2002)
Synaptic regulation of protein synthesis and the fragile X protein
W. Greenough (2001)
Rapid Increase in Clusters of Presynaptic Proteins at Onset of Long-Lasting Potentiation
I. Antonova (2001)
Adult glycogenosis II with paracrystalline mitochondrial inclusions and Hirano bodies in skeletal muscle
R. Fernández (1999)
Regulating actin-filament dynamics in vivo.
H. Chen (2000)
Synaptogenesis Via Dendritic Filopodia in Developing Hippocampal Area CA1
J. Fiala (1998)
Molecular mechanisms of dendritic spine development and remodeling
I. Ethell (2005)
Brain-Derived Neurotrophic Factor Regulation of Retinal Growth Cone Filopodial Dynamics Is Mediated through Actin Depolymerizing Factor/Cofilin
Scott Gehler (2004)
The Mammalian Sec6/8 Complex Interacts with Ca2+ Signaling Complexes and Regulates Their Activity
D. Shin (2000)
A decade of molecular studies of fragile X syndrome.
W. T. O'donnell (2002)
Actin cytoskeleton regulates ion channel activity in retinal neurons
G. Maguire (1998)
Proteomic analysis of corticobasal degeneration: a case study of corticobasal degeneration at the proteome level.
W. Chen (2005)
Local Protein Synthesizing Activity in Axonal Fields Regenerating In Vitro
E. Koenig (1982)
THE FINE STRUCTURE OF SOME INTRAGANGLIONIC ALTERATIONS
A. Hirano (1968)
Hirano bodies and Alzheimer's disease.
S. Mitake (1997)
Shining Light on Depression
T. Insel (2007)
Differential Transport and Local Translation of Cytoskeletal, Injury-Response, and Neurodegeneration Protein mRNAs in Axons
Dianna E Willis (2005)
K+ Channel Facilitation of Exocytosis by Dynamic Interaction with Syntaxin
D. Singer-Lahat (2007)
Cell migration in the forebrain.
O. Marín (2003)
Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity
K. Okamoto (2004)
Evidence that fragile X mental retardation protein is a negative regulator of translation.
B. Laggerbauer (2001)
Presynaptic component of long-term potentiation visualized at individual hippocampal synapses.
A. Malgaroli (1995)
LIMK1 and CLIP-115: linking cytoskeletal defects to Williams syndrome.
C. Hoogenraad (2004)
Numbers of Hirano bodies in the hippocampus of normal and demented people with Alzheimer's disease
P. Gibson (1977)
ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion.
S. L. Ashworth (2003)
Phosphorylation of Actin-Depolymerizing Factor/Cofilin by LIM-Kinase Mediates Amyloid β-Induced Degeneration: A Potential Mechanism of Neuronal Dystrophy in Alzheimer's Disease
L. Heredia (2006)
Structural abnormalities of the cerebral cortex in human chromosomal aberrations: a Golgi study.
M. Marin-Padilla (1972)
Cofilin phosphatases and regulation of actin dynamics.
T. Huang (2006)
Learning Induces Long-Term Potentiation in the Hippocampus
Jonathan R. Whitlock (2006)
Specific organization of intracytoplasmic filaments in the dog testicular interstitial cell
T. Setoguti (2004)
BMPs as Mediators of Roof Plate Repulsion of Commissural Neurons
A. Augsburger (1999)
Localized Activation of p21-Activated Kinase Controls Neuronal Polarity and Morphology
T. Jacobs (2007)
Heat shock induction of intranuclear actin rods in cultured mammalian cells.
K. Iida (1986)
Eosinophilic bodies in some neurones in the thalamus of ageing mice
H. Fraser (1969)
A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease.
J. Murrell (1991)
Binding proteins for mRNA localization and local translation, and their dysfunction in genetic neurological disease
G. Bassell (2004)
Signaling mechanisms that regulate actin‐based motility processes in the nervous system
G. Meyer (2002)
The specification of dorsal cell fates in the vertebrate central nervous system.
K. Lee (1999)
Progressive multifocal leukoencephalopathy with paramyxovirus-like structures, Hirano bodies and neurofibrillary tangles
M. Gary Hadfield (2004)
Review: Fine structure of synaptogenesis in the vertebrate central nervous system
J. Vaughn (1989)
BMP signaling is necessary for neural crest cell migration and ganglion formation in the enteric nervous system
A. Goldstein (2005)
A cytoskeletal-based perimeter fence selectively corrals a sub-population of cell surface Kv2.1 channels
M. Tamkun (2007)
TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines
R. Fujii (2005)
Y. Gillerot (1983)
The Number of Glutamate Receptors Opened by Synaptic Stimulation in Single Hippocampal Spines
E. Nimchinsky (2004)
Cofilin is a component of intranuclear and cytoplasmic actin rods induced in cultured cells.
E. Nishida (1987)
Hirano‐bodies in the distal symmetric polyneuropathy of the spontaneously diabetic BB‐Wistar rat
A. Sima (1983)
Hippocampal seizures cause depolymerization of filamentous actin in neurons independent of acute morphological changes
Y. Ouyang (2007)
Reversible translocation of cytoplasmic actin into the nucleus caused by dimethyl sulfoxide.
J. Sanger (1980)
Etiological heterogeneity of familial periventricular heterotopia and hydrocephalus
V. Sheen (2004)
Expression analysis of actin-related genes as an underlying mechanism for mood disorders.
N. Nakatani (2007)
Screening for the β-amyloid precursor protein mutation (APP717: Val → Ile) in extended pedigrees with early onset Alzheimer's disease
M. Chartier‐Harlin (1991)
Nuclear actin bundles in Amoeba, Dictyostelium and human HeLa cells induced by dimethyl sulfoxide.
Y. Fukui (1979)
Cytoplasmic linker proteins promote microtubule rescue in vivo
Y. Komarova (2002)
Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination.
M. K. Lim (2007)
Hirano body in an inflammatory cell of leptomeningeal vessel infected by fungus paecilomyces
K. Ho (2004)
Actin is closely associated with RNA polymerase II and involved in activation of gene transcription.
X. Zhu (2004)
The pathophysiology of primary dystonia.
A. Berardelli (1998)
Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective
R. Tanzi (2005)
Dystonia musculorum deformans. Analysis with electromyography.
N. Yanagisawa (1971)
Essential requirement for Rho family GTPase signaling in Pax3 induced mesenchymal-epithelial transition.
O’Neil Wiggan (2006)
Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
R. Ehehalt (2003)
Amyloid β interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease
A. Lorenzo (2000)
Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1
R. Vadlamudi (2002)
Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene
M. Chartier-Harlin (1991)
The function of dendritic spines: devices subserving biochemical rather than electrical compartmentalization
C. Koch (1993)
Role of actin cytoskeleton in dendritic spine morphogenesis
Y. Sekino (2007)
CRIM1 Regulates the Rate of Processing and Delivery of Bone Morphogenetic Proteins to the Cell Surface*
L. Wilkinson (2003)
Organizing principles of real-time memory encoding: neural clique assemblies and universal neural codes
L. Lin (2006)
The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines.
A. Peters (1970)
The Neuron Doctrine, Redux
T. Bullock (2005)
The HEM proteins: a novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis.
S. Baumgartner (1995)
Classification of dystonia.
S. Fahn (1998)
Eps8 controls actin-based motility by capping the barbed ends of actin filaments
A. Disanza (2004)
Structural basis of long-term potentiation in single dendritic spines
Masanori Matsuzaki (2004)
Analysis of epitopes shared by Hirano bodies and neurofilament proteins in normal and Alzheimer's disease hippocampus.
M. L. Schmidt (1989)
Neurodegenerative stimuli induce persistent ADF/cofilin–actin rods that disrupt distal neurite function
L. Minamide (2000)
Caspase cleavage of members of the amyloid precursor family of proteins
V. Galván (2002)
Actin-binding proteins take the reins in growth cones
C. Pak (2008)
Hippocampal LTP Is Accompanied by Enhanced F-Actin Content within the Dendritic Spine that Is Essential for Late LTP Maintenance In Vivo
Y. Fukazawa (2003)
Regulation of Growth Cone Actin Dynamics by ADF/Cofilin1
Ravine A. Gungabissoon (2003)
Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease
G. Stokin (2005)
Electron microscopic observations on the cerebellar cortex in kuru.
E. J. Field (1969)
Intracytoplasmic eosinophilic inclusions in the neurons of the central nervous system
C. Pena (2004)
Two actin binding proteins, actin depolymerizing factor and cofilin, are associated with Hirano bodies.
S. Maciver (1995)
Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites
F. R. Schubert (2001)
The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure
K. Okamoto (2007)
Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate.
N. Allbritton (1992)
β-Secretase-Cleaved Amyloid Precursor Protein Accumulates at Actin Inclusions Induced in Neurons by Stress or Amyloid β: A Feedforward Mechanism for Alzheimer's Disease
M. Maloney (2005)
Snyaptic and dendritic development and mental defect.
P. Huttenlocher (1975)
The KKRKK sequence is involved in heat shock-induced nuclear translocation of the 18-kDa actin-binding protein, cofilin.
K. Iida (1992)
Brain-Derived Neurotrophic Factor Promotes Long-Term Potentiation-Related Cytoskeletal Changes in Adult Hippocampus
Christopher Rex (2007)
Ultrastructure of Hirano bodies
S. S. Schochet (2004)
Renal ischemia induces tropomyosin dissociation-destabilizing microvilli microfilaments.
S. L. Ashworth (2004)
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
A. Verkerk (1991)
Aβ1-42 stimulates actin polymerization in hippocampal neurons through Rac1 and Cdc42 Rho GTPases
A. Mendoza-Naranjo (2007)
Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease
Li-xia Zhao (2006)
Actin depolymerizing factor and cofilin phosphorylation dynamics: response to signals that regulate neurite extension.
P. J. Meberg (1998)
Bone morphogenetic protein signalling and vertebrate nervous system development
A. Liu (2005)
Nucleotide exchange between cytosolic ATP and F-actin-bound ADP may be a major energy-utilizing process in unstimulated platelets.
J. Daniel (1986)
Synaptic connections of morphologically identified and physiologically characterized large basket cells in the striate cortex of cat
P. Somogyi (1983)
Pax genes and organogenesis
E. Dahl (1997)
Abnormal Spine Morphology and Enhanced LTP in LIMK-1 Knockout Mice
Yanghong Meng (2002)
Dephosphorylation of cofilin accompanies heat shock-induced nuclear accumulation of cofilin.
Y. Ohta (1989)
Postsynaptic actin and neuronal plasticity
A. Matus (1999)
Evidence for a Role of Dendritic Filopodia in Synaptogenesis and Spine Formation
N. Ziv (1996)
Calcium Signal-induced Cofilin Dephosphorylation Is Mediated by Slingshot via Calcineurin*
Yan Wang (2005)
Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP‐dependent dendritogenesis
Si Tuen Lee-Hoeflich (2004)
Cdc42 Regulates Cofilin during the Establishment of Neuronal Polarity
Boyan K. Garvalov (2007)
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
J. Hardy (2002)
[Spine biology in psychiatric diseases].
T. Takumi (2007)
This paper is referenced by
Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses
Sarah R. Gilman (2011)
Cytoskeletal pathologies of Alzheimer disease.
J. Bamburg (2009)
Actin in axons: stable scaffolds and dynamic filaments.
Paul C. Letourneau (2009)
The axonal cytoskeleton: from organization to function
J. Kevenaar (2015)
Calcium-mediated mechanisms of retinal ganglion cell degeneration during autoimmune optic neuritis
Jovana Bojcevski (2017)
Network based analysis of genetic disease associations
Sarah R. Gilman (2013)
A Genetically Encoded Reporter for Real-Time Imaging of Cofilin-Actin Rods in Living Neurons
Jianjie Mi (2013)
Functional diversity of actin cytoskeleton in neurons and its regulation by tropomyosin.
G. Schevzov (2012)