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Introduction To Cellular Signal Transduction

A. Sitaramayya
Published 1999 · Biology

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The mechanism of information transfer between cells is the subject of this text. In the past, aspects of this field were the domain of different disciplines, including endocrinology, neurochemistry, and pharmacology. However, in recent years, signal transduction has emerged as an independent discipline. This book covers the major topics in signal transduction: receptors which recognize the signal molecules at the cell surface; G-proteins which induce the signals; and adenylate cyclases, granylate cyclases, and prospholipases which generate the second messenger. The discussion focuses on ion channels, prosphodiesterases and protein kinases, which participate in the ultimate cellular response to signals, the health consequences of defects in signal transduction proteins, and the central role signal transduction plays in drug abuse. This volume is designed to be a reference source for investigators in the field, and is aimed at students interested in an overall understanding of the concepts involved in cell signalling. The topics are covered with the goal of preparing the reader for an in-depth examination.
This paper references
10.1073/PNAS.74.10.4238
A light-activated GTPase in vertebrate photoreceptors: regulation of light-activated cyclic GMP phosphodiesterase.
G. L. Wheeler (1977)
10.1038/342762A0
Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel
U. Kaupp (1989)
10.1073/PNAS.92.17.7864
Olfactory transduction is intrinsically noisy.
G. Lowe (1995)
10.1021/BI952711T
Characterization of two recombinant PDE3 (cGMP-inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells.
M. J. Leroy (1996)
Regulation of phosphatidate phosphatase activity from the yeast Saccharomyces cerevisiae by sphingoid bases.
W. Wu (1993)
10.1016/0968-0004(93)80001-R
A template for the protein kinase family.
S. Taylor (1993)
10.1016/0090-6980(87)90288-7
Increased arachidonic acid metabolites from cells in culture after treatment with the phosphatidylcholine-hydrolyzing phospholipase C from Bacillus cereus.
L. Levine (1987)
10.1021/BI00409A033
A Fourier-transform infrared spectroscopic study of the phosphoserine residues in hen egg phosvitin and ovalbumin.
J. M. Sanchez-Ruiz (1988)
10.1016/S0960-9822(09)00454-0
ARF and PITP restore GTPγS-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis
A. Fensome (1996)
Ca2+ -independent cytosolic
factor (1994)
10.1074/jbc.271.20.11694
Cytokines and Insulin Induce Cationic Amino Acid Transporter (CAT) Expression in Cardiac Myocytes
W. W. Simmons (1996)
10.1021/BI961659D
Interfacial catalysis by human 85 kDa cytosolic phospholipase A2 on anionic vesicles in the scooting mode.
T. Bayburt (1997)
10.1021/BI962512P
Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
L. Essen (1997)
10.1523/JNEUROSCI.11-11-03624.1991
Calcium-activated chloride conductance in frog olfactory cilia
S. J. Kleene (1991)
10.1016/0378-1119(95)00002-N
Toxic phospholipases D of Corynebacterium pseudotuberculosis, C. ulcerans and Arcanobacterium haemolyticum: cloning and sequence homology.
P. McNamara (1995)
10.1016/S0149-7634(89)80013-2
The discovery of self-stimulation and other stories
P. Milner (1989)
10.1017/S0033583500004571
Electrical activity of vertebrate photoreceptors.
T. Tomita (1970)
10.1038/374272A0
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
R. Bond (1995)
10.1016/s0021-9258(19)47208-6
Insulin-stimulated protein tyrosine phosphorylation in intact cells evaluated by giant two-dimensional gel electrophoresis.
R. Levenson (1989)
10.1126/SCIENCE.2166336
Protein tyrosine phosphatase activity of an essential virulence determinant in Yersinia.
K. Guan (1990)
10.1073/PNAS.93.24.14188
Identification and tissue-specific expression of PDE7 phosphodiesterase splice variants.
T. Bloom (1996)
10.1016/0896-6273(93)90213-B
Drug addiction: A model for the molecular basis of neural plasticity
E. Nestler (1993)
10.1038/325442A0
A cyclic nucleotide-gated conductance in olfactory receptor cilia
T. Nakamura (1987)
10.1073/PNAS.86.22.9030
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
D. Bredt (1989)
10.1074/jbc.272.13.8256
Saccharomyces cerevisiae Homologs of Mammalian B and B′ Subunits of Protein Phosphatase 2A Direct the Enzyme to Distinct Cellular Functions*
Y. Zhao (1997)
Differential regulation of bovine brain calmodulin-dependent cyclic nucleotide phosphodiesterase isozymes by cyclic AMP-dependent protein kinase and calmodulin-dependent phosphatase ( cell calcium / protein phosphorylation )
R. Sharma
10.1074/JBC.270.50.29640
Human ADP-ribosylation Factor-activated Phosphatidylcholine-specific Phospholipase D Defines a New and Highly Conserved Gene Family (*)
S. Hammond (1995)
Phospholipases
X. (1993)
Nitric oxide inhibits sodium reabsorption in the isolated perfused cortical collecting duct.
B. A. Stoos (1995)
10.1074/jbc.271.2.1111
Regulation of Cytokine-inducible Nitric Oxide Synthase in Cardiac Myocytes and Microvascular Endothelial Cells
K. Singh (1996)
10.1016/S0009-3084(96)02630-8
Kinetics of phosphatidylinositol-specific phospholipase C with vesicles of a thiophosphate analogue of phosphatidylinositol.
H. Hendrickson (1996)
10.1085/JGP.108.6.525
T-type Ca2+ channel lowers the threshold of spike generation in the newt olfactory receptor cell
F. Kawai (1996)
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon-gamma and bacterial lipopolysaccharide.
Q. Xie (1993)
10.1074/jbc.272.20.12881
Protein Kinase A Anchoring*
M. Dell'acqua (1997)
10.1016/0005-2744(72)90060-5
Separation of multiple molecular forms of cyclic adenosine-3',5'-monophosphate phosphodiesterase in rat cerebellum by polyacrylamide gel electrophoresis.
P. Uzunov (1972)
G-protein-regulated phospholipases C, D and A2-mediated signalling in neutrophils.
S. Cockcroft (1992)
10.1073/PNAS.90.13.5889
Signal transduction via the MAP kinases: proceed at your own RSK.
J. Blenis (1993)
10.1021/BI00024A003
Enhancement of Agkistrodon piscivorus piscivorus venom phospholipase A2 activity toward phosphatidylcholine vesicles by lysolecithin and palmitic acid: studies with fluorescent probes of membrane structure.
M. Sheffield (1995)
10.1016/0968-0004(94)90127-9
Inhibitors of protein kinases and phosphatases.
C. MacKintosh (1994)
10.1016/0014-5793(95)01134-Z
Up‐regulation of endothelial nitric oxide synthase expression by cyclic guanosine 3′,5′‐monophosphate
L. V. Ravichandran (1995)
10.1016/s0021-9258(17)37441-0
Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene.
N. Chartrain (1994)
10.1016/S0022-2836(83)80328-3
Structure of porcine pancreatic phospholipase A2 at 2.6 A resolution and comparison with bovine phospholipase A2.
B. W. Dijkstra (1983)
Phosphatidate phosphohydrolases in liver, heart and adipose tissue of the JCR:LA corpulent rat and the lean genotypes: implications for glycerolipid synthesis and signal transduction.
Z. Jamal (1992)
10.1152/AJPRENAL.1986.251.2.F379
Atrial peptides inhibit oxygen consumption in kidney medullary collecting duct cells.
M. Zeidel (1986)
10.1073/PNAS.90.15.7240
Nitric oxide activates cyclooxygenase enzymes.
D. Salvemini (1993)
10.1073/PNAS.87.23.9226
Interferon gamma response region in the promoter of the human DPA gene.
Z. Yang (1990)
10.1016/0092-8674(94)90557-6
Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses
M. Xu (1994)
10.1016/S0167-5699(97)01002-5
A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells.
C. E. Hack (1997)
10.1038/367639A0
Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness
V. R. Rao (1994)
Theophylline as a tool in studies of the role of cyclic adenosine 3',5'-monophosphate in hormone-induced lipolysis.
S. Hynie (1966)
10.1016/0968-0004(89)90086-8
Signal transduction via phosphatidylcholine cycles
S. Pelech (1989)
10.1016/S0014-2999(97)00065-4
Pharmacology and regulation of the neuronal dopamine transporter.
M. E. Reith (1997)
10.1021/BI00852A006
The assay of adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate in biological materials by enzymatic radioisotopic displacement.
G. Brooker (1968)
10.1111/j.1471-4159.1992.tb08332.x
Effect of Nitroprusside (Nitric Oxide) on Endogenous Dopamine Release from Rat Striatal Slices
X. Zhu (1992)
Cyclic GMP synthesis and function.
S. Waldman (1987)
The catalytic core domain of Ca2+
ization Sontag et al (1997)
Signal transduction pathways in response to protein misfolding in the extracytoplasmic compartments of E
D Missiakas (1997)
10.1016/s0021-9258(18)62703-6
Hydrolysis of cyclic guanosine and adenosine 3',5'-monophosphates by rat and bovine tissues.
J. Beavo (1970)
10.1016/s0021-9258(18)95888-6
Subcellular Distribution of Adenyl Cyclase and Cyclic Phosphodiesterase in Rat Brain Cortex
E. D. Robertis (1967)
Structure/function studies of the rod phosphodiesterase subunit
D Takemoto (1992)
However, with the acquisition of a library of amino
britsen (1983)
10.1073/PNAS.89.24.11993
Nitric oxide synthase in macula densa regulates glomerular capillary pressure.
C. Wilcox (1992)
Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens.
H. Nye (1995)
10.1021/BI960602O
Stereocontrolled syntheses of water-soluble inhibitors of phosphatidylinositol-specific phospholipase C: inhibition enhanced by an interface.
Y. Wu (1997)
10.1006/ABBI.1996.0276
The effects of nitric oxide on electron transport complexes.
R. Welter (1996)
10.1006/BBRC.1996.0193
Nitric oxide-donor compounds inhibit lipoxygenase activity.
M. Maccarrone (1996)
10.1073/PNAS.90.8.3462
Nitric oxide/cGMP pathway stimulates phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, in the substantia nigra.
K. Tsou (1993)
10.1038/nsb1295-1043
Protein tyrosine phosphatases take off
D. Barford (1995)
10.1085/JGP.100.1.45
Properties of cyclic nucleotide-gated channels mediating olfactory transduction. Activation, selectivity, and blockage
S. Frings (1992)
10.1074/jbc.272.4.2346
Evidence That Porcine Pancreatic Phospholipase A2 via Its High Affinity Receptor Stimulates Extracellular Matrix Invasion by Normal and Cancer Cells*
G. Kundu (1997)
10.1016/0929-7855(94)00029-C
Phosphoinositide hydrolysis by phospholipase C modulated by multivalent cations La(3+), Al(3+), neomycin, polyamines, and melittin.
L. J. McDonald (1995)
10.1172/JCI115908
Polymerase chain reaction localization of constitutive nitric oxide synthase and soluble guanylate cyclase messenger RNAs in microdissected rat nephron segments.
Y. Terada (1992)
10.1074/JBC.270.10.5130
Phosphatidylinositol 4,5-Bisphosphate Synthesis Is Required for Activation of Phospholipase D in U937 Cells (*)
P. Pertile (1995)
10.1113/jphysiol.1990.sp018295
The response induced by intracellular cyclic AMP in isolated olfactory receptor cells of the newt.
T. Kurahashi (1990)
10.1016/0006-291X(89)92117-7
Cyclic and noncyclic inositol phosphates are formed at different ratios by phospholipase C isozymes.
J. Kim (1989)
10.1073/PNAS.91.12.5387
Two distinct signaling pathways trigger the expression of inducible nitric oxide synthase in rat renal mesangial cells.
D. Kunz (1994)
10.1111/j.1365-2958.1993.tb01622.x
Bacterial and bacteriophage protein phosphatases
E. Koonin (1993)
Membrane potential-dependent ion channels in cell membrane : phylogenetic and developmental approaches
S. Hagiwara (1983)
10.1016/s0021-9258(17)42060-6
Cloning and expression of a membrane receptor for secretory phospholipases A2.
G. Lambeau (1994)
10.1016/s0021-9258(19)67782-3
The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells.
R. Kramer (1991)
10.1016/s0021-9258(19)41069-7
Purification and properties of the light-activated cyclic nucleotide phosphodiesterase of rod outer segments.
N. Miki (1975)
10.1146/ANNUREV.NE.09.030186.000511
Cyclic GMP cascade of vision.
L. Stryer (1986)
10.1096/fasebj.5.13.1680765
Guanylyl cyclases, a growing family of signal‐transducing enzymes
D. Koesling (1991)
10.1074/jbc.272.17.11118
Pancreatic Islets Express a Ca2+-independent Phospholipase A2 Enzyme That Contains a Repeated Structural Motif Homologous to the Integral Membrane Protein Binding Domain of Ankyrin*
Z. Ma (1997)
10.1074/JBC.270.33.19422
Purification and Characterization of a Novel Plasma Membrane Phosphatidate Phosphohydrolase from Rat Liver (*)
D. W. Waggoner (1995)
Analysis of the electrical activity of the olfactory epithelium.
D. Ottoson (1955)
10.1074/JBC.270.51.30671
An Essential Aspartic Acid at Each of Two Allosteric cGMP-binding Sites of a cGMP-specific Phosphodiesterase (*)
L. McAllister-Lucas (1995)
10.1161/01.HYP.27.3.679
Mechanism of the nitric oxide-induced blockade of collecting duct water permeability.
N. Garcia (1996)
10.1161/01.HYP.25.2.180
Inhibition of endothelial nitric oxide synthase activity by protein kinase C.
K. Hirata (1995)
10.1016/0009-3084(96)02543-1
Sphingoid bases and phospholipase D activation.
S. Spiegel (1996)
10.1016/0092-8674(93)90533-V
The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation
E. Sontag (1993)
A "typical" bacterium possesses up
Stock et al (1994)
10.1172/JCI117977
Flow modulates myogenic responses in isolated microperfused rabbit afferent arterioles via endothelium-derived nitric oxide.
L. A. Juncos (1995)
10.1038/371168A0
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
J. Harlan (1994)
10.1097/00001756-199601310-00055
Nitric oxide regulates NMDA‐induced dopamine release in rat striatum
M. Shibata (1996)
10.1152/physrev.1982.62.4.1377-r
Intracellular pH.
A. Roos (1981)
10.1093/AJH/4.3.260
Mediatory role of endothelium-derived nitric oxide in renal vasodilatory and excretory effects of bradykinin.
V. Lahera (1991)
10.1016/0143-4160(92)90055-W
Ca2+/calmodulin-regulated nitric oxide synthases.
H. Schmidt (1992)
10.1055/S-0029-1211496
Identification of the site in the cGMP-inhibited phosphodiesterase phosphorylated in adipocytes in response to insulin and isoproterenol.
T. Rahn (1996)
10.1016/s0021-9258(18)43894-x
Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide.
L. Castro (1994)
10.1016/s0021-9258(17)37448-3
Modulation of Syrian hamster 3-hydroxy-3-methylglutaryl-CoA reductase activity by phosphorylation. Role of serine 871.
R. V. Omkumar (1994)
10.1111/j.1365-2958.1991.tb02117.x
Detection of a gene encoding a phosphatidylinositol‐specific phospholipase C that is co‐ordinately expressed with listeriolysin in Listeria monocytogenes
M. Leimeister-Wächter (1991)
10.1007/978-1-4615-7858-1
Single-Channel Recording
B. Sakmann (1983)
phorbol ester, NFl, and shear stress regulatory regions (Marsden et a11993, Robinson et aI1994). Shear stress has been shown to increase not only NOS III activity but also mRNA (Awolesi et
L. Garvin (1994)
10.1016/0165-0173(95)00008-9
Plasmalogens, phospholipases A2 and signal transduction
A. Farooqui (1995)
10.1523/JNEUROSCI.14-09-05147.1994
Gases as biological messengers: nitric oxide and carbon monoxide in the brain
T. Dawson (1994)
10.1111/j.1476-5381.1996.tb16717.x
Nitric oxide‐mediated relaxation without concomitant changes in cyclic GMP content of rat proximal colon
T. Takeuchi (1996)
10.1126/SCIENCE.8211181
Arabidopsis ethylene-response gene ETR1: similarity of product to two-component regulators.
C. Chang (1993)
10.1016/s0955-0674(96)80065-2
Heterotrimeric G proteins.
H. Hamm (1996)
10.1016/0006-291X(85)91830-3
The differential stimulation of brain and heart cyclic-AMP phosphodiesterase by oncomodulin.
B. Mutus (1985)
10.1073/PNAS.89.13.5764
Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine.
B. Hope (1992)
10.1016/0968-0004(93)90109-Z
On target with a new mechanism for the regulation of protein phosphorylation.
M. Hubbard (1993)
Further studies on the nature and causes of mutations
HI Muller (1932)
10.1139/M92-220
A phosphatidylinositol-specific phospholipase C from Cytophaga: production, purification, and properties
E. Artursson (1992)
EDRF and the regulation of vascular tone.
Griffith Tm (1989)
10.1021/BI00246A010
Sequence comparison of the 63-, 61-, and 59-kDa calmodulin-dependent cyclic nucleotide phosphodiesterases.
J. Novack (1991)
10.1007/978-3-540-29678-2_1367
Cyclic GMP.
Nelson D. Goldberg (1973)
10.1021/BI00055A009
Phospholipase C-promoted membrane fusion. Retroinhibition by the end-product diacylglycerol.
J. Nieva (1993)
10.1016/0024-3205(93)90559-L
L-NAME and MK-801 attenuate sensitization to the locomotor-stimulating effect of cocaine.
C. Pudiak (1993)
10.1006/GENO.1994.1068
Isolation and chromosomal localization of the human endothelial nitric oxide synthase (NOS3) gene.
L. J. Robinson (1994)
cGMP phosphodiesterase noncatalytic site
A Zhao (1996)
10.1016/0014-5793(91)80095-K
Complete cDNA sequences of mouse rod photoreceptor cGMP phosphodiesterase α‐ and β‐subunits, and identification of β′‐, a putative β‐subunit isozyme produced by alternative splicing of the β‐subunit gene
W. Baehr (1991)
Bovine heart protein activator of cyclic nucleotide phosphodiesterase.
Wang Jh (1975)
10.1016/s0021-9258(17)38603-9
Glycosyl-sn-1,2-dimyristylphosphatidylinositol is covalently linked to Trypanosoma brucei variant surface glycoprotein.
M. Ferguson (1985)
10.1016/B978-012078160-7/50023-8
Chapter 20 – The Nitric Oxide–Cyclic GMP Signaling System
T. Lincoln (1996)
10.1016/0300-9629(85)90467-0
Ionic Channels of Excitable Membranes
B. V. Hille (1984)
Interaction of the gamma-subunit of retinal rod outer segment phosphodiesterase with transducin. Use of synthetic peptides as functional probes.
D. F. Morrison (1989)
10.1016/0167-4889(95)00198-0
Relevance of the arginine transport activity to the nitric oxide synthesis in mouse peritoneal macrophages stimulated with bacterial lipopolysaccharide.
T. Shibazaki (1996)
10.1084/JEM.173.3.751
Listeria monocytogenes mutants lacking phosphatidylinositol-specific phospholipase C are avirulent
A. Camilli (1991)
10.1126/science.2274785
Interfacial catalysis: the mechanism of phospholipase A2
D. Scott (1990)
10.1152/AJPRENAL.1993.264.2.F344
Exogenous cGMP prevents decrease in diuresis and natriuresis induced by inhibition of NO synthesis.
V. Lahera (1993)
10.1016/0306-9877(95)90128-0
Nitric oxide regulation of ADP-ribosylation of G proteins in hypertension.
N. Kanagy (1995)
10.1006/BBRC.1994.1251
The role of a phosphatidylcholine-specific phospholipase C in the production of diacylglycerol for nitric oxide synthesis in macrophages activated by IFN-gamma and LPS.
W. Sands (1994)
10.1074/jbc.270.45.26731
Induction of Nitric Oxide Synthase mRNA Expression
M. Colasanti (1995)
10.1016/0005-2744(69)90249-6
Cyclic 3',5'-nucleotide phosphodiesterase. Preparation of a partially inactive enzyme and its subsequent stimulation by snake venom.
W. Cheung (1969)
10.1074/jbc.271.47.29529
Regulation of Phosphatidic Acid Phosphohydrolase by Epidermal Growth Factor
Y. Jiang (1996)
10.1016/0306-4522(95)00207-Y
Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system
M. Berhow (1995)
10.1016/0005-2744(74)90048-5
Separation of multiple forms of cyclic nucleotide phosphodiesterases from rat brain by isoelectrofocusing.
W. J. Pledger (1974)
10.1074/jbc.271.40.24800
Ceramide Inhibits Phospholipase D in a Cell-free System*
M. Venable (1996)
10.1096/fasebj.7.12.8397130
EPR characterization of molecular targets for NO in mammalian cells and organelles
Y. Henry (1993)
10.1038/316255A0
Odorant-sensitive adenylate cyclase may mediate olfactory reception
U. Pace (1985)
10.1093/NAR/19.4.775
Activation of junB by PKC and PKA signal transduction through a novel cis-acting element.
R. D. de Groot (1991)
Peptide mapping of cyclic nucleotide phosphodiesterases.
D. Takemoto (1984)
10.1038/288373A0
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
R. Furchgott (1980)
10.1016/0092-8674(91)90461-7
PDGF stimulation of inositol phospholipid hydrolysis requires PLC-γ1 phosphorylation on tyrosine residues 783 and 1254
H. K. Kim (1991)
Homozygous individuals would show the lethal
Pollak (1993)
Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase.
J. Liu (1994)
10.1146/ANNUREV.BB.25.060196.001443
Activating mutations of rhodopsin and other G protein-coupled receptors.
V. R. Rao (1996)
10.1016/s0021-9258(19)50039-4
Growth factor stimulation of phospholipase C-gamma 1 activity. Comparative properties of control and activated enzymes.
M. Wahl (1992)
10.1016/0014-5793(87)80530-6
Cyclic GMP phosphodiesterase from bovine retina Amino acid sequence of the α‐subunit and nucleotide sequence of the corresponding cDNA
Yu. A. Ovchinnikov (1986)
10.1097/00008877-199308000-00021
Incentive-sensitization As The Basis Of Drug Craving
T. Robinson (1993)
10.1016/0300-9629(78)90065-8
Effects of different ionic environments on the responses of single olfactory receptors in the lamprey
Suzuki Noriyo (1978)
10.1093/NAR/24.12.2236
Inhibition of NF-κB DNA Binding by Nitric Oxide
J. R. Matthews (1996)
10.1042/BJ3210805
Differential regulation of phospholipase D and phospholipase A2 by protein kinase C in P388D1 macrophages.
J. Balsinde (1997)
10.1073/PNAS.88.17.7773
Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein.
D. Stuehr (1991)
10.1073/PNAS.88.24.11305
Characterization of the promoter of the human gene encoding the high-affinity IgG receptor: transcriptional induction by gamma-interferon is mediated through common DNA response elements.
R. Pearse (1991)
10.1016/0163-7258(91)90039-O
Cyclic nucleotide phosphodiesterases: pharmacology, biochemistry and function.
W. Thompson (1991)
10.1085/JGP.99.4.505
Voltage-dependent and odorant-regulated currents in isolated olfactory receptor neurons of the channel catfish
T. Miyamoto (1992)
10.1161/01.RES.78.6.998
Nitric oxide synthase (NOS3)-mediated cholinergic modulation of Ca2+ current in adult rabbit atrioventricular nodal cells.
X. Han (1996)
10.1126/science.1902986
Diversity of G proteins in signal transduction
M. Simon (1991)
10.1016/S0167-4889(96)00148-6
Phospholipase A2 has a role in proliferation but not in differentiation of HL-60 cells.
Y. Liu (1997)
Reversible and irreversible activation of cyclic nucleotide phosphodiesterase: separation of the regulatory and catalytic domains by limited proteolysis.
M. Krinks (1984)
10.1074/JBC.271.36.22240
Identification of Key Amino Acids in a Conserved cGMP-binding Site of cGMP-binding Phosphodiesterases
I. Turko (1996)
10.1172/JCI117825
Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases.
R. R. Reinhardt (1995)
10.1126/SCIENCE.1846707
Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.
A. Smrcka (1991)
10.1038/368545A0
Direct modulation by Ca2+–calmodulin of cyclic nucleotide-activated channel of rat olfactory receptor neurons
T. Chen (1994)
10.1126/SCIENCE.2499043
Golf: an olfactory neuron specific-G protein involved in odorant signal transduction.
D. Jones (1989)
10.1021/BI00044A002
A novel calcium-dependent activator of retinal rod outer segment membrane guanylate cyclase.
N. Pozdnyakov (1995)
10.1016/0921-8696(90)90013-S
Single cyclic nucleotide-activated ion channel activity in olfactory receptor cell soma membrane.
N. Suzuki (1990)
10.1016/0166-6851(92)90180-R
Glycosyl phosphatidylinositol-specific phospholipase C of Trypanosoma brucei: expression in Escherichia coli.
K. Mensa-Wilmot (1992)
10.1161/01.RES.77.4.841
Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves.
P. Schwarz (1995)
10.1016/0898-6568(94)00044-1
Regulation of signalling pathways to the nucleus by dopaminergic receptors.
P. Rogue (1994)
10.1163/2211730X96X00216
Evidence for involvement of ventral tegmental area cyclic AMP systems in behavioral sensitization to psychostimulants.
B. Tolliver (1996)
10.1021/BI00496A018
Amino acid sequence of the cyclic GMP stimulated cyclic nucleotide phosphodiesterase from bovine heart.
H. L. Trong (1990)
10.1016/0003-9861(71)90540-6
The effect of nucleotides and a nondialyzable factor on the hydrolysis of cyclic AMP by a cyclic nucleotide phosphodiesterase from beef heart.
E. Goren (1971)
10.1016/0896-6273(88)90168-7
Cyclic GMP depresses hippocampal Ca2+ current through a mechanism independent of cGMP-dependent protein kinase
D. Doerner (1988)
10.1038/321066A0
Single cyclic GMP-activated channel activity in excised patches of rod outer segment membrane
L. W. Haynes (1986)
10.1161/01.RES.76.4.634
Acetylcholine elicits a rebound stimulation of Ca2+ current mediated by pertussis toxin-sensitive G protein and cAMP-dependent protein kinase A in atrial myocytes.
Y. Wang (1995)
10.1146/ANNUREV.BI.64.070195.003253
Interfacial enzymology of glycerolipid hydrolases: lessons from secreted phospholipases A2.
M. Gelb (1995)
10.1146/ANNUREV.BI.61.070192.003015
Neuronal Ca2+/calmodulin-dependent protein kinases.
P. Hanson (1992)
10.1002/CBF.290120304
Regulation of nitric oxide synthase and soluble guanylyl cyclase
Bernd Mayer (1994)
Nitric oxide: physiology, pathophysiology, and pharmacology.
S. Moncada (1991)
10.1161/01.HYP.23.6.1040
Blockade of distal nephron sodium transport attenuates pressure natriuresis in dogs.
D. Majid (1994)
10.1073/PNAS.69.7.1791
3':5'-cyclic adenosine monophosphate phosphodiesterase: negative cooperativity.
T. Russell (1972)
10.1126/science.175.4023.757
Cyclic Nucleotide Phosphodiesterase: High Activity in a Mammalian Photoreceptor
R. Pannbacker (1972)
10.1152/PHYSREV.1997.77.2.303
Phospholipase D: enzymology, mechanisms of regulation, and function.
J. Exton (1997)
10.1113/jphysiol.1993.sp019550
Contribution of the ciliary cyclic nucleotide‐gated conductance to olfactory transduction in the salamander.
G. Lowe (1993)
Protein kinases and DNA repair
TM Gottlieb (1994)
193. Cyclic GMP-stimulated Cyclic Nucleotide Phosphodiesteraseの構造と機能について : 第34群 内分泌 VI
山本 稔彦 (1985)
10.1016/S0014-2999(96)00646-2
Regulation of the functional activity of the human dopamine transporter by the arachidonic acid pathway.
L. Zhang (1996)
10.1006/JCIS.1995.1059
Synthesis and Characterization of Short-Chain Diacylphosphatidic Acids
V. Garigapati (1995)
Structure-function relationships among cyclic nucleotide phosphodiesterases
H. Charbonneau (1990)
Purification of a Ca2+-activatable cyclic nucleotide phosphodiesterase from bovine heart by specific interaction with its Ca2+-dependent modulator protein.
H. C. Ho (1977)
Endothelial nitric oxide generating enzyme(s
KM Boje (1990)
10.1159/000136274
Cyclic 3’, 5’-AMP Phosphodiesterase in Isolated Fat Cells
P. Schoenhoefer (1972)
10.1126/SCIENCE.7684161
Mechanotransduction across the cell surface and through the cytoskeleton
Ning Wang (1993)
10.1111/J.1432-1033.1984.TB08522.X
The protein phosphatases involved in cellular regulation
N. Tonks (1984)
Allosteric activation of phosphatidylinosi
C Zhou (1997)
10.1016/s0021-9258(17)33203-9
Cyclic adenosine 3':5'-monophosphate phosphodiesterase. Distinct forms in human lymphocytes and monocytes.
W. Thompson (1976)
10.1016/s0021-9258(19)47335-3
Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate.
K. Guan (1991)
10.1002/PRO.5560021102
New insights into protein‐tyrosine kinase receptor signaling complexes
M. Fry (1993)
10.1007/978-94-009-0083-7_21
Molecular aspects of signal transduction of shear stress in the endothelial cell.
A. Malek (1994)
10.1016/0888-7543(90)90567-E
Molecular characterization of human and bovine rod photoreceptor cGMP phosphodiesterase alpha-subunit and chromosomal localization of the human gene.
S. Pittler (1990)
10.1074/jbc.272.6.3573
Structural Aspects of Interfacial Adsorption
S. Han (1997)
10.1113/jphysiol.1993.sp019721
Gating properties of the cAMP‐gated channel in toad olfactory receptor cells.
T. Kurahashi (1993)
10.1016/0003-9861(70)90460-1
Preparation and properties of a cyclic 3',5'-nucleotide phosphodiesterase isolated from frog erythrocytes.
O. Rosen (1970)
10.1042/BJ2880407
A competitive inhibitor of phospholipase A2 decreases surfactant phosphatidylcholine degradation by the rat lung.
A. Fisher (1992)
10.1016/0165-6147(92)90062-B
Neurobiology of opiate abuse.
G. Di Chiara (1992)
10.1152/AJPCELL.1996.270.4.C1153
Phospholipase activation and secretion: evidence that PLA2, PLC, and PLD are not essential to exocytosis.
J. Coorssen (1996)
10.1016/0968-0004(94)90135-X
Histidine and aspartate phosphorylation: two-component systems and the limits of homology.
R. Swanson (1994)
10.1016/0014-5793(91)80317-V
Sequence homologies between guanylyl cyclases and structural analogies to other signal‐transducing proteins
D. Koesling (1991)
10.1074/JBC.270.42.25200
Cloning, Sequencing, and Expression of a 24-kDa Ca2+-binding Protein Activating Photoreceptor Guanylyl Cyclase (*)
A. Dizhoor (1995)
10.1006/BBRC.1995.1813
An extracellular inositol phospholipid-specific phospholipase C is released by cultured Swiss 3T3 cells.
G. Birrell (1995)
Amyl nitrate in angina pectoris
Brunton TL. (1867)
10.1016/S0167-4838(96)00114-8
Vanadate is a potent competitive inhibitor of phospholipase C from Bacillus cereus.
C. Tan (1996)
10.1073/pnas.88.7.2936
Osteoclastic inhibition: an action of nitric oxide not mediated by cyclic GMP.
I. Macintyre (1991)
10.1042/BJ3050745
src-homology 2 (SH2) domain ligation as an allosteric regulator: modulation of phosphoinositide-specific phospholipase C gamma 1 structure and activity.
K. Koblan (1995)
10.1038/347689A0
X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor
Marjolein M. G. M. Thunnissen (1990)
Phospholipase A2: a model for membrane-bound enzymes
HM Verheij (1981)
Inhibition of nitric oxide synthase augments myocardial contractile responses to ~-adrenergic stimulation
JF JrKeaney (1996)
10.1016/s0021-9258(18)62207-0
Characterization of cyclic nucleotide phosphodiesterases of rat tissues.
W. Thompson (1971)
10.1016/s0021-9258(18)33316-7
Peptide mapping of multiple forms of cyclic nucleotide phosphodiesterase.
D. Takemoto (1982)
10.1016/s0021-9258(18)64253-x
Enzymatic hydrolysis of adenosine 3',5'-phosphoric acid.
G. Drummond (1961)
10.1021/BI00734A008
Effect of insulin and growth hormone on rat liver cyclic nucleotide phosphodiesterase.
W. Thompson (1973)
10.1016/0006-291X(70)90199-3
Calcium dependent phosphodiesterase activity and its activating factor (PAF) from brain studies on cyclic 3',5'-nucleotide phosphodiesterase (3).
S. Kakiuchi (1970)
Regulation of CREB expression: in vivo evidence for a functional role in morphine action in the nucleus accumbens.
K. L. Widnell (1996)
10.1172/JCI115481
Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator.
J. Cooke (1991)
10.1210/MEND.10.12.8961278
G proteins of the Gq family couple the H2 histamine receptor to phospholipase C.
B. Kühn (1996)
10.1016/0005-2736(94)90186-4
Effect of vesicle composition and curvature on the dissociation of phosphatidic acid in small unilamellar vesicles--a 31P-NMR study.
M. Swairjo (1994)
10.1038/369242A0
A two-component system that regulates an osmosensing MAP kinase cascade in yeast
T. Maeda (1994)
10.1021/BI961541X
Use of an imperfect neutral diluent and outer vesicle layer scooting mode hydrolysis to analyze the interfacial kinetics, inhibition, and substrate preferences of bee venom phospholipase A2.
B. Yu (1997)
10.2210/PDB1PP2/PDB
The refined crystal structure of dimeric phospholipase A2 at 2.5 A. Access to a shielded catalytic center.
S. Brunie (1985)
10.1016/0929-7855(96)00527-5
Effects of acid phospholipids on ARF activities: potential roles in membrane traffic.
R. Kahn (1996)
10.3109/10715769309145868
The reaction of no with superoxide.
R. E. Huie (1993)
10.1021/BI00571A026
Subunit structure and catalytic properties of bovine brain Ca2+-dependent cyclic nucleotide phosphodiesterase.
C. Klee (1979)
10.1016/0896-6273(94)90061-2
Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments
B. Hope (1994)
10.1111/j.1476-5381.1990.tb14151.x
Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
D. Rees (1990)
10.1038/323273A0
Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells
H. Hartzell (1986)
10.1016/0304-4165(91)90037-H
Cholinesterase solubilizing factor from Cytophaga sp. is a phosphatidylinositol-specific phospholipase C.
K. Jaeger (1991)
10.1096/fasebj.9.9.7601337
The MAPK signaling cascade
R. Seger (1995)
10.1038/380595A0
Crystal structure of a mammalian phosphoinositide-specific phospholipase Cδ
L. Essen (1996)
10.1074/JBC.270.15.8466
Regulation of Phospholipase D in HL60 Cells
A. R. Siddiqi (1995)
10.1016/0006-291X(76)90494-0
Affinity chromatography purification of a cyclic nucleotide phosphodiesterase using immobilized modulator protein, a troponin C-like protein from brain.
D. Watterson (1976)
10.1152/PHYSREV.1996.76.2.425
Paracrine regulation of the renal microcirculation.
L. G. Navar (1996)
10.1172/JCI117585
Endothelial nitric oxide synthase is expressed in cultured human bronchiolar epithelium.
P. Shaul (1994)
10.1126/science.271.5255.1586
Opposite Modulation of Cocaine-Seeking Behavior by D1- and D2-Like Dopamine Receptor Agonists
D. Self (1996)
10.1016/S0896-6273(00)80111-7
Addiction to Cocaine and Amphetamine
S. E. Hyman (1996)
10.1038/338357A0
High-resolution (1.5 Å) crystal structure of phospholipase C from Bacillus cereus
E. Hough (1989)
10.1007/978-3-642-16483-5_4540
[Phospholipase D].
T. Taki (1986)
Recent studies with transgenic mice, in which the fos B
Nye (1995)
10.1073/PNAS.92.8.3551
Constitutive activation of phototransduction by K296E opsin is not a cause of photoreceptor degeneration.
T. Li (1995)
10.1021/BI00865A020
Purification and properties of 3',5'-cyclic nucleotide phosphodiesterase from dog heart.
K. Nair (1966)
10.1016/0005-2760(93)90229-3
Metal ion and salt effects on the phospholipase A2, lysophospholipase, and transacylase activities of human cytosolic phospholipase A2.
L. Reynolds (1993)
10.1038/344336A0
Dual ion-channel regulation by cyclic GMP and cyclic GMP-dependent protein kinase
D. B. Light (1990)
10.1111/j.1749-6632.1992.tb25957.x
Common Intracellular Actions of Chronic Morphine and Cocaine in Dopaminergic Brain Reward Regions a
D. Beitner-Johnson (1992)
Role of nitric oxide and its interaction with superoxide in the suppression of cardiac muscle mitochondrial respiration
Xie Y-Wand Wolin MS. (1996)
The catalytic subunit of bovine brain platelet-activating factor acetylhydrolase is a novel type of serine esterase.
M. Hattori (1994)
10.1074/jbc.271.5.2574
Activation of Protein Phosphatase 1
Y. Chu (1996)
10.1016/0009-3084(96)02541-8
Biochemistry and cell biology of phospholipase D in human neutrophils.
S. Olson (1996)
10.1073/PNAS.84.16.5540
Phospholipase C associated with particulate fractions of bovine brain.
K. Y. Lee (1987)
10.1007/978-1-4613-0651-1_6
Molecular aspects of phospholipase A2 activation.
R. Biltonen (1990)
10.1113/jphysiol.1987.sp016678
Properties of ion channels closed by light and opened by guanosine 3',5'‐cyclic monophosphate in toad retinal rods.
G. Matthews (1987)
10.1113/jphysiol.1989.sp017868
Activation by odorants of cation‐selective conductance in the olfactory receptor cell isolated from the newt.
T. Kurahashi (1989)
10.1128/JB.178.10.2749-2756.1996
Identification of a Bacillus thuringiensis gene that positively regulates transcription of the phosphatidylinositol-specific phospholipase C gene at the onset of the stationary phase.
D. Lereclus (1996)
10.1021/BI00127A028
Ca2+/calmodulin-dependent NO synthase type I: a biopteroflavoprotein with Ca2+/calmodulin-independent diaphorase and reductase activities.
H. Schmidt (1992)
10.1210/EDRV-12-3-218
Hormonal regulation of cyclic nucleotide phosphodiesterases.
M. Conti (1991)
Nitric oxide inhibits norepinephrine uptake into cardiac sympathetic neurons
DM Kaye (1995)
10.1113/jphysiol.1991.sp018787
The spatial distributions of odorant sensitivity and odorant‐induced currents in salamander olfactory receptor cells.
G. Lowe (1991)
10.1016/s0021-9258(18)52889-1
Endothelial nitric oxide synthase. N-terminal myristoylation determines subcellular localization.
L. Busconi (1993)
10.1016/s0021-9258(19)44414-1
Purification and properties of the protein activator of bovine heart cyclic adenosine 3',5'-monophosphate phosphodiesterase.
T. S. Teo (1973)
NITRIC OXIDE SYNTHASE REGULATORY SITES: PHOSPHORYLATION BY CYCLIC AMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE C, AND CALCIUM/CALMODULIN BINDING SITES
D. Bredt (1992)
10.1042/BJ3070799
Characterization of a regulated form of phospholipase D in the yeast Saccharomyces cerevisiae.
K. M. Ella (1995)
10.1006/BBRC.1996.0106
In situ identification of messenger RNA of endothelial type nitric oxide synthase in rat cardiac myocytes.
T. Seki (1996)
10.1074/JBC.271.39.24164
Inhibition of Phospholipase D Activity by Fodrin
S. Lukowski (1996)
10.1038/236285b0
Crystal Structure
W. A. Wooster (1972)
10.1073/PNAS.86.10.3659
S-phase induction and transformation of quiescent NIH 3T3 cells by microinjection of phospholipase C.
M. Smith (1989)
10.1016/0092-8674(95)90409-3
Phospholipid signaling
N. Divecha (1995)
Cyclic 3',5'-nucleotide phosphodiesterases of Novikoff rat hepatoma, mouse L, and HeLa cells growing in suspension culture.
J. Schröder (1972)
Molecular mechanisms of drug addiction: adaptations in signal transduction pathways.
E. Nestler (1996)
10.1523/JNEUROSCI.13-02-00423.1993
Coordinate expression of c-fos and jun B is induced in the rat striatum by cocaine
R. Moratalla (1993)
10.1016/0022-2836(92)90938-G
Crystal structures of phosphate, iodide and iodate-inhibited phospholipase C from Bacillus cereus and structural investigations of the binding of reaction products and a substrate analogue.
S. Hansen (1992)
10.1042/BJ3210737
High specificity of human secretory class II phospholipase A2 for phosphatidic acid.
Y. Snitko (1997)
10.1152/AJPHEART.1991.261.1.H149
Flow modulation of agonist (ATP)-response (Ca2+) coupling in vascular endothelial cells.
R. Dull (1991)
Role of nitric oxide in progression and regression of atherosclerosis.
J. Cooke (1996)
Inhibition of Cl absorption (JeI) by NO produced in the thick ascending limb (THAL) by endogenous nitric oxide synthase (NOS) increases during salt loading
BA Stoos (1996)
10.1161/01.HYP.13.6.658
Endothelium and Control of Vascular Function State of the Art Lecture
P. VanHoutte (1989)
Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus.
M. Low (1981)
10.1126/science.173.3996.540
Adenosine 3',5'-Monophosphate Phosphodiesterase: Multiple Molecular Forms
E. Monn (1971)
10.1126/science.173.3998.745
Cyclic 3',5'-Nucleotide Phosphodiesterase: Cytochemical Localization in Cerebral Cortex
N. Florendo (1971)
10.1038/KI.1995.396
The renal cGMP-gated cation channel: its molecular structure and physiological role.
D. E. McCoy (1995)
Assay of phosphodiesterase with radioactivity labeled cyclic 3 '5' -AMP as substrate. Naunyn-Schmiedesbergs Archive Fur PharmakoI268:272-299
G Poch (1971)
10.1016/s0021-9258(18)62110-6
Stimulation of adenosine 3',5'-monophosphate hydrolysis by guanosine 3',5'-monophosphate.
J. Beavo (1971)
10.1016/s0021-9258(18)98653-9
Multisite and hierarchal protein phosphorylation.
P. Roach (1991)
(J Biol. Chem., 270(34):19861-19867)Expression and characterization of branched-chain a-keto acid dehydrogenase kinase from the rat. Is it a histidine-protein kinase
J. Davie (1995)
Subunit of Bovine Rod Photoreceptor cGMP Phosphodiesterase
V. Lipkin (1990)
10.1146/ANNUREV.BI.46.070177.004135
Cyclic GMP metabolism and involvement in biological regulation.
Nelson D. Goldberg (1977)
Phosphorylation by protein kinase C modulates agonist binding to striatal dopamine D2 receptors.
P. Rogue (1990)
10.1021/BI9616561
Origin of the lag period in the phospholipase C cleavage of phospholipids in membranes. Concomitant vesicle aggregation and enzyme activation.
G. Basañez (1996)
10.1152/AJPRENAL.1996.270.1.F106
Nitric oxide stimulates guanylate cyclase and regulates sodium transport in rabbit proximal tubule.
A. Roczniak (1996)
10.1016/S0955-0674(96)80061-5
Signal transduction through lipid second messengers.
S. Spiegel (1996)
10.1111/j.1365-2958.1991.tb02118.x
Identification of phosphatidylinositol‐specific phospholipase C activity in Listeria monocytogenes: a novel type of virulence factor?
J. Mengaud (1991)
10.1042/BJ3220353
Induction of cytosolic phospholipase A2 activity by phosphatidic acid and diglycerides in permeabilized human neutrophils: interrelationship between phospholipases D and A2.
S. A. Bauldry (1997)
10.1074/jbc.271.28.16703
Determination of the Structure of the N-terminal Splice Region of the Cyclic AMP-specific Phosphodiesterase RD1 (RNPDE4A1) by 1H NMR and Identification of the Membrane Association Domain Using Chimeric Constructs*
K. J. Smith (1996)
10.1073/PNAS.83.24.9308
Identification of a conserved domain among cyclic nucleotide phosphodiesterases from diverse species.
H. Charbonneau (1986)
10.1038/363071A0
Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells
T. Kurahashi (1993)
10.1113/jphysiol.1990.sp018061
Currents carried by monovalent cations through cyclic GMP‐activated channels in excised patches from salamander rods.
A. Menini (1990)
10.1083/JCB.134.2.295
Evidence that phospholipase D mediates ADP ribosylation factor- dependent formation of Golgi coated vesicles
N. Ktistakis (1996)
Regulation of nitric oxide synthase by nitric oxide.
A. Rengasamy (1993)
Protein phosphatases: recent progress.
S. Shenolikar (1991)
Phosphorylation of Ser871 impairs the function of His865 of Syrian hamster 3-hydroxy-3-methylglutaryl-CoA reductase.
R. V. Omkumar (1994)
These experiments stimulated further investigation into the identity and mechanism of action of this compound, which we now know is NO
Furchgott (1980)
10.5772/65615
Protein phosphorylation.
C. Rubin (1975)
10.1073/PNAS.89.2.471
Termination of second messenger signaling in olfaction.
I. Boekhoff (1992)
Effects of nitroprusside, glyceryl trinitrate, and 8-bromo cyclic GMP on phosphorylase a formation and myosin light chain phosphorylation in rat aorta.
R. Johnson (1985)
Regulation of PLC
L Wu (1995)
10.1016/0898-6568(95)00076-3
Phosphatidic acid: a lipid messenger involved in intracellular and extracellular signalling.
D. English (1996)
bacterial toxin lipopolysaccharide, and cAMP (Kunz et
Geller et al (1995)
10.1146/ANNUREV.NE.18.030195.002335
Molecular mechanisms of drug reinforcement and addiction.
D. Self (1995)
One thousand and one protein kinases
T Hunter (1987)
Single channel properties of the ciliary cyclic nucleotide-gated conductance
T Nakamura (1988)
10.1523/JNEUROSCI.06-09-02521.1986
Comparison of the light-sensitive and cyclic GMP-sensitive conductances of the rod photoreceptor: noise characteristics
G. Matthews (1986)
10.1176/AJP.148.4.495
Clinical features of cocaine induced paranoia.
S. Satel (1990)
10.1523/JNEUROSCI.11-11-03565.1991
Single odor-sensitive channels in olfactory receptor neurons are also gated by cyclic nucleotides
S. Firestein (1991)
10.1042/BJ3190861
Didecanoyl phosphatidylcholine is a superior substrate for assaying mammalian phospholipase D.
A. Vinggaard (1996)
10.1152/AJPLUNG.1994.267.3.L335
Inhibition of lung calcium-independent phospholipase A2 by surfactant protein A.
A. Fisher (1994)
10.1016/0014-2999(95)00618-4
L-N6-(1-iminoethyl)-lysine potently inhibits inducible nitric oxide synthase and is superior to NG-monomethyl-arginine in vitro and in vivo.
S. Stenger (1995)
10.1152/AJPCELL.1995.269.6.C1371
Regulation of endothelial cell nitric oxide synthase mRNA expression by shear stress.
M. Uematsu (1995)
10.1021/BI00463A018
Phospholipids chiral at phosphorus. Stereochemical mechanism of reactions catalyzed by phosphatidylinositide-specific phospholipase C from Bacillus cereus and guinea pig uterus.
G. Lin (1990)
10.1016/S0039-6060(05)80316-2
Regulation of inducible nitric oxide production by intracellular calcium.
M. Jordan (1995)
10.1016/0169-328X(94)00246-B
Cocaine binges differentially alter striatal preprodynorphin and zif/268 mRNAs.
J. Daunais (1995)
Serine 228 is essential for catalytic activities of 85-kDa cytosolic phospholipase A2.
J. Sharp (1994)
The regulation and cellular functions of PC hydrolysis
MM Billah (1990)
Cyclic 3',5'-nucleotide phosphodiesterase. Evidence for and properties of a protein activator.
W. Cheung (1971)
10.1101/SQB.1965.030.01.023
A physiologic and pharmacologic study of olfactory receptors.
D. Tucker (1965)
10.1038/317252A0
Light-suppressible, cyclic GMP-sensitive conductance in the plasma membrane of a truncated rod outer segment
K. Yau (1985)
10.1126/SCIENCE.8073283
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
D. E. Coleman (1994)
Fractionation and characterization of a cyclic adenine ribonucleotide formed by tissue particles.
E. Sutherland (1958)
10.1016/0014-5793(82)80319-0
Discovery of A Ca2+‐and calmodulin‐dependent protein phosphatase
A. Stewart (1982)
The enzyme may be found in either
phocytes Reinhardt (1995)
Basic and Clinical Pharmacology
B. Katzung (1982)
10.1021/BI00074A003
Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.
I. Street (1993)
10.1006/BBRC.1993.1092
Stimulation of rat liver microsomal cGMP-inhibited cAMP phosphodiesterase (PDE III) by phospholipase C and D.
F. Carpenedo (1993)
10.1021/BI961720E
Palmitoylation of endothelial nitric oxide synthase is necessary for optimal stimulated release of nitric oxide: implications for caveolae localization.
J. Liu (1996)
10.1021/AC60306A041
3',5'-cyclic adenosine monophosphate phosphodiesterase assay using high speed liquid chromatography.
S. Pennington (1971)
Cyclic strain increases endothelial nitric oxide synthase activity.
M. Awolesi (1994)
10.1074/jbc.270.6.2517
Glycan Requirements of Glycosylphosphatidylinositol Phospholipase C from Trypanosoma brucei
P. Liu (1995)
10.3891/ACTA.CHEM.SCAND.35B-0039
Effect of some divalent metal cations on phospholipase C from Bacillus cereus.
C. Little (1981)
10.1016/s0021-9258(19)68134-2
Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from bovine tissues.
T. J. Martins (1982)
10.1016/s0021-9258(17)46693-2
Purification and characterization of bovine brain platelet-activating factor acetylhydrolase.
M. Hattori (1993)
Physiological effects of inverse agonists in transgenic mice
RA Bond (1995)
Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis
A. B. Hancock (1996)
Cyclic nucleotide phosphodiesterase.
W. Cheung (1970)
10.1146/ANNUREV.PH.57.030195.003423
Nitric oxide synthases: properties and catalytic mechanism.
O. Griffith (1995)
10.1016/0167-4889(93)90006-B
The nitric oxide and cGMP signal transduction system: regulation and mechanism of action.
H. Schmidt (1993)
10.1016/0006-291X(91)91279-L
Phosphorylation of nitric oxide synthase by protein kinase A.
B. Brüne (1991)
10.1126/SCIENCE.3541204
The molecular genetics of cancer.
J. Bishop (1987)
Chronic cocaine treatment suppresses basal expression of zif268 in rat forebrain: in situ hybridization studies.
R. Bhat (1992)
Molecular cloning and complete amino acid sequence of form-l phosphoinositide-specific phospholipase C
CF Bennet (1988)
10.1016/0003-9861(78)90480-0
Phosphatidyl inositol-specific phospholipase C from Clostridium novyi type A.
R. Taguchi (1978)
10.1016/0896-6273(93)90192-T
Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
K. Yamagata (1993)
10.1016/S0968-0004(96)20031-3
The growing phospholipase A2 superfamily of signal transduction enzymes.
E. Dennis (1997)
10.1146/annurev.bi.37.070168.001053
Cyclic AMP.
G. A. Robison (1968)
10.1016/0929-7855(96)00525-1
Phosphatidylcholine hydrolysis and protein kinase C activation for intracellular signaling network.
S. Nakamura (1996)
10.1128/IAI.64.7.2440-2444.1996
Use of site-directed mutagenesis to probe structure-function relationships of alpha-toxin from Clostridium perfringens.
I. Guillouard (1996)
An electrophysiological characterization of ciliated olfactory receptor cells of the coho salmon Oncorhynchus kisutch.
G. Nevitt (1992)
10.1128/JB.177.22.6510-6517.1995
Isolation and cloning of a protein-serine/threonine phosphatase from an archaeon.
J. Leng (1995)
10.1006/ABBI.1993.1016
Inhibition of cytochromes P450 by nitric oxide and a nitric oxide-releasing agent.
D. Wink (1993)
10.1083/JCB.128.6.1131
A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle
E. Sontag (1995)
Phosphorylation of an inhibitory subunit of cGMP phosphodiesterase in Rana catesbeiana rod photoreceptors. I. Characterization of the phosphorylation.
S. Tsuboi (1994)
10.1038/370216A0
Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor
Mitsuharu Hattori (1994)
Vesicle membrane association of nitric oxide synthase in primary mouse macrophages.
Y. Vodovotz (1995)
10.1006/PREP.1997.0756
Cloning, overexpression, refolding, and purification of the nonspecific phospholipase C from Bacillus cereus.
C. Tan (1997)
10.1128/JB.178.16.4759-4764.1996
Fancy meeting you here! A fresh look at "prokaryotic" protein phosphorylation.
P. Kennelly (1996)
The role of protein phosphoryla
J Beltman (1993)
10.1016/0076-6879(81)71086-3
[84] Phosphatidylinositol-specific phospholipase C from Bacillus cereus and Bacillus thurinǵiensis
H. Ikezawa (1981)
10.1042/BJ2960293
Phosphohistidine and phospholysine phosphatase activities in the rat: potential protein-lysine and protein-histidine phosphatases?
C. Wong (1993)
10.1016/s0021-9258(19)47113-5
Atrial natriuretic peptide-dependent phosphorylation of smooth muscle cell particulate fraction proteins is mediated by cGMP-dependent protein kinase.
B. Sarcevic (1989)
10.1016/s0021-9258(18)54354-4
Structure and function studies of the cGMP-stimulated phosphodiesterase.
S. Stroop (1991)
synaptic regions of brain
Robertis et al (1968)
10.1146/ANNUREV.PH.57.030195.003303
Nitric oxide as a neurotransmitter in peripheral nerves: nature of transmitter and mechanism of transmission.
M. Rand (1995)
10.1074/JBC.270.3.995
Agonist-modulated Palmitoylation of Endothelial Nitric Oxide Synthase (*)
L. J. Robinson (1995)
10.1016/0076-6879(91)00141-I
Analyzing protein phosphorylation in prokaryotes.
J. Cortay (1991)
10.1152/AJPRENAL.1994.267.5.F748
In situ hybridization localization of mRNA encoding inducible nitric oxide synthase in rat kidney.
K. Y. Ahn (1994)
The role of insulin-sensitive phosphodiesterase in insulin action.
H. Makino (1992)
10.1074/JBC.270.23.14214
Induction and Stabilization of IκBα by Nitric Oxide Mediates Inhibition of NF-κB (*)
Hai-bing Peng (1995)
Immunologic approaches to the study of cyclic nucleotide phosphodiesterases.
R. Hurwitz (1984)
10.1046/j.1471-4159.1995.65062706.x
Differential Effects of D1 and D2 Dopamine Receptor Antagonists on Acute Amphetamine‐ or Methamphetamine‐Induced Up‐Regulation of zif/268 mRNA Expression in Rat Forebrain
J. Wang (1995)
10.1523/JNEUROSCI.16-15-04707.1996
Regulation of ERK ( Extracellular Signal Regulated Kinase), Part of the Neurotrophin Signal Transduction Cascade, in the Rat Mesolimbic Dopamine System by Chronic Exposure to Morphine or Cocaine
M. Berhow (1996)
10.1042/BJ3070069
Mutations within a highly conserved sequence present in the X region of phosphoinositide-specific phospholipase C-delta 1.
M. Ellis (1995)
10.1159/000113838
Transduction mechanisms in the olfactory and vomeronasal organs of turtles.
T. Shoji (1993)
10.1523/JNEUROSCI.11-02-00435.1991
Voltage-gated currents in identified rat olfactory receptor neurons
P. Trombley (1991)
10.1074/jbc.272.13.8576
Identity between the Ca2+-independent Phospholipase A2 Enzymes from P388D1 Macrophages and Chinese Hamster Ovary Cells*
M. Balboa (1997)
10.1016/0006-291X(63)90566-7
Isolation of adenosine 3', 5'-monophosphate and guanosine 3', 5'-monophosphate from rat urine.
D. Ashman (1963)
10.1016/0006-291X(71)90525-0
Cyclic 3',5'-nucleotide phosphodiesterase, IV. Two enzymes with different properties from brain.
S. Kakiuchi (1971)
10.1073/PNAS.91.20.9574
Identification of a phosphatidic acid-preferring phospholipase A1 from bovine brain and testis.
H. Higgs (1994)
10.1007/BF00208802
Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor
B. Berg (1995)
10.1074/JBC.271.26.15468
Phosphatidylinositol Phospholipase C Is Activated Allosterically by the Aminoglycoside G418
J. Morris (1996)
10.1016/0006-291X(68)90224-6
Adenyl cyclase activity in the chronically denervated cat heart.
B. Sobel (1968)
10.1152/AJPRENAL.1995.268.5.F885
Topography of nitric oxide synthesis by localizing constitutive NO synthases in mammalian kidney.
S. Bachmann (1995)
10.1210/EDRV-15-2-135
The family of guanylyl cyclase receptors and their ligands.
J. G. Drewett (1994)
10.1016/s0021-9258(18)92038-7
Control of the Metabolism and Lipolytic Effects of Cyclic 3',5'-Adenosine Monophosphate in Adipose Tissue by Insulin, Methyl Xanthines, and Nicotinic Acid
M. Blecher (1968)
10.1016/0076-6879(91)97138-O
Phospholipase A2-catalyzed hydrolysis of vesicles: uses of interfacial catalysis in the scooting mode.
M. Jain (1991)
10.1146/ANNUREV.BB.22.060193.001215
The effects of phosphorylation on the structure and function of proteins.
L. Johnson (1993)
10.1093/PROTEIN/7.4.571
A proposal for the catalytic mechanism in phospholipase C based on interaction energy and distance geometry calculations.
S. Sundell (1994)
Purification and characterization of a new isozyme of thiol:protein-disulfide oxidoreductase from rat hepatic microsomes
Srivastava Sp (1991)
10.1126/SCIENCE.7540771
Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B.
Z. Jia (1995)
10.1073/PNAS.86.6.1796
Molecular cloning of rat type 2C (IA) protein phosphatase mRNA.
S. Tamura (1989)
10.1152/AJPHEART.1995.269.2.H550
Constitutive NOS expression in cultured endothelial cells is elevated by fluid shear stress.
V. Ranjan (1995)
10.1038/nm0895-792
Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice
N. Kohl (1995)
10.1016/0006-291X(67)90508-6
Cyclic 3',5'-nucleotide phosphodiesterase: pronounced stimulation by snake venom.
W. Y. Cheung (1967)
10.1152/AJPLUNG.1997.272.2.L238
Role of acidic Ca2+-independent phospholipase A2 in synthesis of lung dipalmitoyl phosphatidylcholine.
A. Fisher (1997)
10.1021/JM960434Y
Synthesis, structure-activity relationships, and the effect of polyethylene glycol on inhibitors of phosphatidylinositol-specific phospholipase C from Bacillus cereus.
M. Ryan (1996)
10.1093/EURHEARTJ/11.SUPPL_B.35
Endothelium-dependent modulation of vascular tone and platelet function.
U. Pohl (1990)
10.1006/JMBI.1993.1572
Crystal structure of phospholipase C from Bacillus cereus complexed with a substrate analog.
S. Hansen (1993)
Nitric oxide: a signal
B Brune (1993)
10.1038/347184A0
Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons
R. S. Dhallan (1990)
Nitric oxide synthase inhibitor alters papillary muscle force-frequency relationship.
M. Finkel (1995)
10.1111/j.1476-5381.1993.tb12798.x
7‐Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti‐nociceptive activity in the mouse without increasing blood pressure
P. Moore (1993)
10.1074/JBC.270.46.27577
Angiotensin II Stimulates System y+ and Cationic Amino Acid Transporter Gene Expression in Cultured Vascular Smooth Muscle Cells (*)
B. C. Low (1995)
10.1126/SCIENCE.8080500
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity.
J. Zhang (1994)
10.1016/0024-3205(72)90146-4
Characterization of multiple cyclic nucleotide phosphodiesterase activities of rat adipose tissue
U. Klotz (1972)
10.1146/ANNUREV.CB.08.110192.002335
1002 protein phosphatases?
H. Charbonneau (1992)
10.1021/BI00487A010
Phosphatidylinositol-specific phospholipase C from Bacillus cereus combines intrinsic phosphotransferase and cyclic phosphodiesterase activities: a 31P NMR study.
J. Volwerk (1990)
10.1016/0014-2999(90)90531-A
Nω-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation
K. Ishii (1990)
10.1002/j.1460-2075.1995.tb00086.x
Solution structure of porcine pancreatic phospholipase A2.
B. Berg (1995)
10.1016/0014-5793(93)81190-B
Activation of phosphatidylinositol lipid‐specific phospholipase C‐β3 by G‐protein βγ subunits
A. Carozzi (1993)
10.1016/s0021-9258(18)98436-x
Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases.
P. Kennelly (1991)
Advances in Cyclic Nucleotide and Protein Phosphorylation Research
P. Greengard (1975)
Brain-stimulation reward as a model of drug-induced euphoria: comparison of cocaine and opiates
C. (1992)
10.1016/s0021-9258(17)36961-2
Functional effect of phosphorylation of the photoreceptor phosphodiesterase inhibitory subunit by protein kinase C.
I. Udovichenko (1994)
10.1016/s0021-9258(18)93463-0
Activation of skeletal muscle phosphorylase kinase by adenosine triphosphate and adenosine 3',5'-monophosphate.
R. Delange (1968)
10.1016/s0021-9258(17)37546-4
Molecular cloning of pancreatic group I phospholipase A2 receptor.
J. Ishizaki (1994)
10.1016/0003-9861(73)90540-7
Phospholipase A2 activity towards phosphatidylcholine in mixed micelles: surface dilution kinetics and the effect of thermotropic phase transitions.
E. Dennis (1973)
10.1126/SCIENCE.2541501
Studies of inositol phospholipid-specific phospholipase C.
S. Rhee (1989)
10.1128/JB.170.6.2763-2769.1988
Nucleotide sequence of aceK, the gene encoding isocitrate dehydrogenase kinase/phosphatase.
D. Klumpp (1988)
10.1111/J.1432-1033.1996.0105U.X
Inhibition by gangliosides of Bacillus cereus phospholipase C activity against monolayers, micelles and bilayer vesicles.
J. J. Daniele (1996)
10.1021/BI00246A009
Evidence for domain organization within the 61-kDa calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine brain.
H. Charbonneau (1991)
10.1021/BI960601W
Activation of phosphatidylinositol-specific phospholipase C toward inositol 1,2-(cyclic)-phosphate.
C. Zhou (1997)
10.1016/0006-291X(66)90358-5
Puromycin: a potent metabolic effect independent of protein synthesis.
M. Appleman (1966)
10.1146/ANNUREV.PH.57.030195.003343
Nitric oxide signaling in the central nervous system.
J. Garthwaite (1995)
10.1097/00000658-199404000-00009
Nitric Oxide Modulates Water and Electrolyte Transport in the Ileum
M. Barry (1994)
10.1002/j.1460-2075.1995.tb00057.x
Crystal structure of the phosphatidylinositol‐specific phospholipase C from Bacillus cereus in complex with myo‐inositol.
D. W. Heinz (1995)
10.1126/SCIENCE.1411571
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C.
Y. Nishizuka (1992)
10.1021/BI00085A014
Substrate requirements of bacterial phosphatidylinositol-specific phospholipase C.
K. A. Lewis (1993)
10.1152/AJPRENAL.1995.268.4.F770
Cytokines activate inducible nitric oxide synthase gene transcription in inner medullary collecting duct cells.
M. Mohaupt (1995)
10.1038/376307A0
Protein molecules as computational elements in living cells
D. Bray (1995)
10.1128/JB.178.1.136-142.1996
Cloning, purification, and properties of a phosphotyrosine protein phosphatase from Streptomyces coelicolor A3(2).
Y. Li (1996)
10.3181/00379727-137-35577
Assay of Cyclic 3′,5′-Nucleotide Phosphodiesterase in Tissue Homogenates 1
P. Gulyassy (1971)
10.1007/s002329900081
Calcium-dependent Modulation of the Agonist Affinity of the Mammalian Olfactory Cyclic Nucleotide-gated Channel by Calmodulin and a Novel Endogenous Factor
S. Balasubramanian (1996)
10.1146/ANNUREV.MED.47.1.219
Nitric oxide synthase: role as a transmitter/mediator in the brain and endocrine system.
T. Dawson (1996)
A chemilumines
M Lucas (1995)
10.1016/S0065-230X(08)60835-0
SH2 and SH3 domains in signal transduction.
T. Pawson (1994)
Isolation and characterization of cGMP phosphodiesterase from bovine rod outer segments.
W. Baehr (1979)
10.1084/JEM.172.6.1599
Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts
G. Werner-felmayer (1990)
10.1016/0165-6147(90)90066-H
Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors.
J. Beavo (1990)
Calmodulin and Ca2+-dependent phosphorylation and dephosphorylation of 63-kDa subunit-containing bovine brain calmodulin-stimulated cyclic nucleotide phosphodiesterase isozyme.
R. Sharma (1986)
10.1111/J.1432-1033.1994.TB18618.X
Conservation analysis and structure prediction of the protein serine/threonine phosphatases. Sequence similarity with diadenosine tetraphosphatase from Escherichia coli suggests homology to the protein phosphatases.
G. Barton (1994)
10.1021/BI00856A017
Properties of cyclic 3',5'-nucleotide phosphodiesterase from rat brain.
W. Cheung (1967)
An electrophysiological survey of frog olfactory cilia.
S. J. Kleene (1994)
GTPase-inhibiting mutations activate the alpha-chain of Gs in human tumours.
L. Vallar (1990)
10.1073/PNAS.91.22.10488
Oncogenic potential of guanine nucleotide stimulatory factor alpha subunit in thyroid glands of transgenic mice.
F. Michiels (1994)
10.1016/0006-291X(86)91065-X
Antibodies prepared to Bacillus cereus phospholipase C crossreact with a phosphatidylcholine preferring phospholipase C in mammalian cells.
M. Clark (1986)
Identification of PI-PLC beta 1, gamma 1, and delta 1 in rat liver: subcellular distribution and relationship to inositol lipid nuclear signalling.
V. Bertagnolo (1995)
10.1126/SCIENCE.1948070
Structures of free and inhibited human secretory phospholipase A2 from inflammatory exudate.
D. Scott (1991)
Activation of the beta 1 isozyme of phospholipase C by alpha subunits of the Gq class of G proteins.
S. J. Taylor (1991)
10.1161/01.RES.58.3.407
Cyclic Guanosine Monophosphate Inhibition of Contraction May be Mediated through Inhibition of Phosphatidylinositol Hydrolysis in Rat Aorta
R. Rapoport (1986)
10.1016/0028-3908(94)90023-X
Cyclic nucleotide dependent phosphorylation of neuronal nitric oxide synthase inhibits catalytic activity
J. Dinerman (1994)
10.1038/313310A0
Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment
E. E. Fesenko (1985)
10.1152/JN.1995.74.1.479
Odor-induced currents in Xenopus olfactory receptor cells measured with perforated-patch recording.
A. Zhainazarov (1995)
Thermodynamic analyses of the growth and structure of asymmetric linear short-chain lecithin micelles based on small angle neutron scattering data
Lin T-L (1987)
10.1113/jphysiol.1985.sp015561
The ionic selectivity and calcium dependence of the light‐sensitive pathway in toad rods.
A. Hodgkin (1985)
10.1074/JBC.270.1.263
A Structure-Function Study of Bovine Pancreatic Phospholipase A Using Polymerized Mixed Liposomes (*)
Raj S. Dua (1995)
Molecular and biochemical features of poly(ADP-ribose) synthetase in neurotoxicity
D Lautier (1993)
10.1016/0092-8674(92)90236-6
Adenylyl cyclases
W. Tang (1992)
Influences of cyclic guanosine 3'5'-monophosphate on the enzymatic hydrolysis of adenosine 3'5'-monophosphate
U Klotz (1972)
Co- and Post-Translational Modification of Proteins: Chemical Principles and Biological Effects
D. Graves (1994)
10.1016/0092-8674(93)90617-Y
Mutations in the human Ca2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism
M. Pollak (1993)
10.1016/s0021-9258(19)74313-0
Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation.
P. Méry (1993)
10.1016/s0021-9258(18)52994-x
The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans.
C. Samuel (1993)
Regulation of phospholipase A2 activation by phosphorylation in mouse peritoneal macrophages.
Z. Qiu (1993)
10.2210/pdb1gym/pdb
PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C IN COMPLEX WITH GLUCOSAMINE-(ALPHA-1-6)-MYO-INOSITOL
D. W. Heinz (1996)
10.1016/0014-5793(94)01453-8
An SH3 domain is required for the mitogenic activity of microinjected phospholipase C‐γ1
P. Huang (1995)
Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene.
P. Marsden (1993)
10.1016/0959-437X(94)90087-6
SH2/SH3 signaling proteins.
J. Schlessinger (1994)
10.1002/PRO.5560050513
A novel family of phospholipase D homologues that includes phospholipid synthases and putative endonucleases: Identification of duplicated repeats and potential active site residues
C. Ponting (1996)
10.1523/JNEUROSCI.14-10-06239.1994
Inactivation of Gi and G(o) proteins in nucleus accumbens reduces both cocaine and heroin reinforcement
D. Self (1994)
10.1016/0006-291X(71)90507-9
Cyclic GMP stimulation and inhibition of cyclic AMP phosphodiesterase from thymic lymphocytes.
D. Franks (1971)
Identification of some novel inhibitors of the vascular nitric oxide synthase in vitro and in vivo
DD Rees (1990)
In the central nervous system NOS I is found in the cerebellum, cerebral cortex, dorsal root ganglion, and hippocampus, among others (Dawson and Dawson
nals Schwartz et al (1995)
10.1037/e496052006-001
Activation of Immediate Early Genes By Drugs of Abuse : (NIDA Research Monograph ; 125)
R. Grzanna (1993)
10.1097/00001756-199401120-00007
Nitric oxide modulates endogenous dopamine release in bovine retina.
O. Bugnon (1994)
10.1016/S0959-4388(96)80079-1
Neurobiology of addiction
R. Wise (1996)
10.2210/PDB4ICD/PDB
Regulation of isocitrate dehydrogenase by phosphorylation involves no long-range conformational change in the free enzyme.
J. Hurley (1990)
10.1016/0169-328X(94)90295-X
Differential induction of Fos protein and a Fos-related antigen following acute and repeated cocaine administration.
J. Rosen (1994)
10.1152/AJPHEART.1991.261.2.H487
Selective inhibition of cGMP-inhibitable cAMP phosphodiesterase decreases pulmonary vasoreactivity.
J. Haynes (1991)
10.1038/376745A0
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1
J. Goldberg (1995)
10.1042/BJ1950645
Purification and properties of the insulin-stimulated cyclic AMP phosphodiesterase from rat liver plasma membranes.
R. J. Marchmont (1981)
10.1016/0006-8993(90)90605-B
Ca2+-dependent adaptive properties in the solitary olfactory receptor cell of the newt
T. Kurahashi (1990)
10.1096/fasebj.10.10.8751718
Phospholipases: structural and functional motifs for working at an interface
M. Roberts (1996)
10.1016/0076-6879(91)01035-Z
Classification of protein-serine/threonine phosphatases: identification and quantitation in cell extracts.
P. Cohen (1991)
Gold of 200-1000 Ilm-2 (Kurahashi and Kaneko 1993, Kleene 1994), while in the dendrite or cell body the channel density is only a few Ilm-2 (Kurahashi
G.H.T. Kurahashi (1993)
10.1016/S0741-5214(96)70276-8
Role of nitric oxide in the effect of blood flow on neointima formation.
M. Ellenby (1996)
10.1074/jbc.271.50.32028
Up-Regulation of Protein Kinase C-ε Promotes the Expression of Cytokine-inducible Nitric Oxide Synthase in RAW 264.7 Cells*
M. J. Díaz-Guerra (1996)
10.1111/j.1476-5381.1996.tb15734.x
Cyclic GMP‐independent effects of nitric oxide on guinea‐pig uterine contractility
K. Kuenzli (1996)
10.1016/0076-6879(89)77015-4
Phosphorus-31 nuclear magnetic resonance of phosphoproteins.
H. Vogel (1989)
10.1016/0014-5793(87)80383-6
Modulation of retinal transducin and phosphodiesterase activities by synthetic peptides of the phosphodiesterase γ‐subunit
D. F. Morrison (1987)
10.1038/313585A0
Cyclic GMP can increase rod outer-segment light-sensitive current 10-fold without delay of excitation
W. Cobbs (1985)
10.1016/S0005-2760(97)00066-0
Diacylglycerol partitioning and mixing in detergent micelles: relevance to enzyme kinetics.
C. Zhou (1997)
10.1074/jbc.271.2.953
Conversion of Lysophospholipids to Cyclic Lysophosphatidic Acid by Phospholipase D (*)
P. Friedman (1996)
10.1074/jbc.271.48.30879
Expression, Purification, and Kinetic Characterization of a Recombinant 80-kDa Intracellular Calcium-independent Phospholipase A2*
M. Wolf (1996)
Cytoplasmic calcium response to fluid
J Ando (1988)
10.1016/0960-9822(92)90345-B
Regulation and function of cyclic nucleotides
J. Bentley (1992)
10.1016/s0021-9258(17)33231-3
Structural similarities between the Ca2+-dependent regulatory proteins of 3':5'-cyclic nucleotide phosphodiesterase and actomyosin ATPase.
D. Watterson (1976)
Subunit structure and catalytic properties of bovine brain cyclic nucleotide PDE
C Klee (1978)
10.1073/PNAS.90.13.6252
Phosphorylation and subcellular translocation of endothelial nitric oxide synthase.
T. Michel (1993)
10.1126/SCIENCE.2443973
A glycan-phosphatidylinositol-specific phospholipase D in human serum.
M. A. Davitz (1987)
10.1016/0165-6147(91)90519-X
The expanding family of guanylyl cyclases.
S. Schulz (1991)
10.1074/jbc.272.13.8567
A Novel Cytosolic Calcium-independent Phospholipase A2 Contains Eight Ankyrin Motifs*
J. Tang (1997)
10.1021/BI00204A023
Fluorescence studies of phosphatidylcholine micelle mixing: relevance to phospholipase kinetics.
C. E. Soltys (1994)
10.1021/BI00088A005
Polymerizable phosphatidylcholines: importance of phospholipid motions for optimum phospholipase A2 and C activity.
C. E. Soltys (1993)
10.1016/0006-291X(67)90398-1
Lipolytic action of 3,3'5-triiodo-L-thyronine, a cyclic AMP phosphodiesterase inhibitor.
L. R. Mandel (1967)
10.1073/PNAS.89.14.6348
Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform.
S. Lamas (1992)
10.1016/0092-8674(91)90556-E
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
J. D. Clark (1991)
10.1006/GENO.1994.1039
Localization of the human gene for inducible nitric oxide synthase (NOS2) to chromosome 17q11.2-q12.
P. Marsden (1994)
10.1073/PNAS.90.2.522
Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes.
D. Geller (1993)
NOS II is primarily found in the cytosol as a soluble enzyme, although there is at least one report showing that it is associated with intracellular vesicles (Vodovotz et aI1995)
L. Garvin (1994)
10.1098/rspb.1991.0148
Inhibition of the olfactory cyclic nucleotide gated ion channel by intracellular calcium
F. Zufall (1991)
10.1097/00001756-199205000-00008
Role of nitric oxide in NMDA-evoked release of [3H]-dopamine from striatal slices.
I. Hanbauer (1992)
10.1139/O96-051
"Cross talk" between the bioactive glycerolipids and sphingolipids in signal transduction.
D. Brindley (1996)
10.1042/BJ2880001
Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors.
S. Cockcroft (1992)
10.1111/j.1476-5381.1989.tb11833.x
A specific inhibitor of nitric oxide formation from l‐arginine attenuates endothelium‐dependent relaxation
D. Rees (1989)
10.1073/PNAS.89.9.3721
Molecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase.
E. Meacci (1992)
10.1161/01.RES.74.5.970
8-bromo-cGMP reduces the myofilament response to Ca2+ in intact cardiac myocytes.
A. M. Shah (1994)
10.1164/AJRCCM.149.2.7508323
The biology of nitrogen oxides in the airways.
B. Gaston (1994)
10.1128/MCB.12.1.128
A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C.
Q. C. Vega (1992)
10.1073/PNAS.90.7.2623
Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of inositol 1,4,5-trisphosphate production.
P. Ruth (1993)
Cyclic nucleotide derivatives as probes of phosphodiesterase catalytic and regulatory sites.
C. Erneux (1984)
10.2210/pdb1bp2/pdb
STRUCTURE OF BOVINE PANCREATIC PHOSPHOLIPASE A2 AT 1.7 ANGSTROMS RESOLUTION
B. W. Dijkstra (1981)
10.1016/0306-4522(95)00100-W
A single injection of amphetamine or methamphetamine induces dynamic alterations in c-fos,zif/268 and preprodynorphin messenger RNA expression in rat forebrain
J. Wang (1995)
10.1016/s0021-9258(17)36703-0
Regulation of biosynthesis of nitric oxide.
C. Nathan (1994)
10.1016/s0021-9258(18)42704-4
Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.
C. Lyons (1992)
10.1073/PNAS.94.19.10397
FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects.
N. Hiroi (1997)
10.1016/0092-8674(95)90405-0
Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling
T. Hunter (1995)
10.1152/AJPRENAL.1995.269.5.F718
Role of NF-kappa B in the regulation of inducible nitric oxide synthase in an MTAL cell line.
B. Kone (1995)
10.1016/0092-8674(91)90418-X
A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
L. Buck (1991)
10.1021/BI00213A016
Characterization of the cardiac troponin I phosphorylation domain by 31P nuclear magnetic resonance spectroscopy.
K. Jaquet (1993)
10.1016/S0006-291X(05)81351-8
Phosphorylation by calcium calmodulin-dependent protein kinase II and protein kinase C modulates the activity of nitric oxide synthase.
M. Nakane (1991)
[Influence of hydrochlorothiazide and other sulfamoyl diuretics on the activity of 3',5'-AMP phosphodiesterase in rat kidney].
G. Senft (1968)
10.1016/0301-4622(94)00153-B
Cyclic nucleotide-gated channels in visual and olfactory transduction.
A. Menini (1995)
10.1038/KI.1992.382
Expression of nitric oxide synthase in kidney macula densa cells.
P. Mundel (1992)
10.1038/KI.1994.318
Differential expression and induction of mRNAs encoding two inducible nitric oxide synthases in rat kidney.
M. Mohaupt (1994)
10.1172/JCI117895
Autocrine inhibition of Na+/K(+)-ATPase by nitric oxide in mouse proximal tubule epithelial cells.
N. Guzman (1995)
10.1016/0028-3908(83)90239-3
Potential antidepressant activity of rolipram and other selective cyclic adenosine 3′,5′-monophosphate phosphodiesterase inhibitors
Helmut Wachtel (1983)
10.1016/S0076-6879(82)81074-4
Real time assay of rod disk membrane cGMP phosphodiesterase and its controller enzymes.
P. Liebman (1982)
Purification of cyclic 3',5'-nucleotide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to Sepharose.
C. Klee (1978)
10.1021/bi00778a018
Multiple cyclic nucleotide phosphodiesterase activities from rat brain.
W. Thompson (1971)
10.1176/AJP.153.2.151
Initiation and adaptation: a paradigm for understanding psychotropic drug action.
S. E. Hyman (1996)
10.1002/9780470123072.CH6
ADP-ribosylation of guanyl nucleotide-binding regulatory proteins by bacterial toxins.
J. Moss (1988)
10.1016/S0167-4889(96)00083-3
How do protein kinases recognize their substrates?
L. Pinna (1996)
Structure of the first C-2 domain of synaptotagrnin
RB Sutton (1995)
10.1126/SCIENCE.1862342
Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase.
D. R. Knighton (1991)
10.5107/SCCJ.32.240
Molecular Mechanisms of the Olfactory Signal Transduction
T. Kurahashi (1998)
10.1016/0021-9797(92)90333-H
Comparison of surface properties and thermodynamic behavior of lyso- and diacylphosphatidylcholines
Jinru Bian (1992)
A second type of rat phosphoinositide-specific phospholipase C containing a src-related sequence not essential for phosphoinositide-hydrolyzing activity.
Y. Emori (1989)
10.1085/JGP.103.1.87
Cyclic nucleotide-gated channels of rat olfactory receptor cells: divalent cations control the sensitivity to cAMP
J. W. Lynch (1994)
10.1161/01.HYP.25.3.415
Regulation of endothelial constitutive nitric oxide synthase by protein kinase C.
Y. O'hara (1995)
10.1021/BI00121A019
Cloning, expression, and catalytic mechanism of the low molecular weight phosphotyrosyl protein phosphatase from bovine heart.
Y. Wo (1992)
The c-fos promoter carries two CREs, one of which is sensitive to both Ca2+ and cAMP (CaRE/CREl) (see review of Rogue and Malviya
M.E.A. Reith Widnell (1996)
10.1002/BIES.20343
Signal transduction in bacterial chemotaxis
J. Stock (1992)
10.1002/PRO.5560050412
Expression, characterization, and crystallization of the catalytic core of rat phosphatidylinositide‐specific phospholipase C δ1
J. Grobler (1996)
10.1016/s0021-9258(18)42284-3
Regulation of inositol phospholipid-specific phospholipase C isozymes.
S. Rhee (1992)
10.1016/s0021-9258(18)60975-5
Inactivation of isocitrate dehydrogenase by phosphorylation is mediated by the negative charge of the phosphate.
P. E. Thorsness (1987)
10.1016/s0021-9258(19)44303-2
Separate phosphodiesterases for the hydrolysis of cyclic adenosine 3',5'-monophosphate and cyclic guanosine 3',5'-monophosphate in rat liver.
T. Russell (1973)
Role of endothelium in the vasodilator response to acetylcholine
RF Furchgott (1981)
Goodman & Gilman's The Pharmacological Basis of Therapeutics
M. Leider (1985)
Isolation and characterization of a y-type phosphoinositide specific phospholipase C (PLCy2)
Y Homma (1990)
activated protein kinase
RA Harris (1995)
10.1074/JBC.270.32.18711
Lipid Signaling Enzymes and Surface Dilution Kinetics (*)
G. Carman (1995)
10.1038/npp.1994.37
Molecular Neurobiology of Drug Addiction
Eric J. Nestler (1994)
10.1146/ANNUREV.PH.58.030196.001043
Defects in G protein-coupled signal transduction in human disease.
A. Spiegel (1996)
Characterization and biological role of the cGMPdependent protein kinase
TM Lincoln (1983)
10.1016/0091-3057(91)90365-9
Marijuana's interaction with brain reward systems: Update 1991
E. Gardner (1991)
10.1006/BBRC.1994.2710
Use of photoacoustic Fourier-transform infrared spectroscopy to study phosphates in proteins.
D. Graves (1994)
10.1111/j.1476-5381.1995.tb13219.x
Increased striatal dopamine efflux in vivo following inhibition of cerebral nitric oxide synthase by the novel monosodium salt of 7‐nitro indazole
M. T. Silva (1995)
10.1016/0014-5793(94)01404-O
Down‐regulation of phospholipase C‐γ1 during the differentiation of U937 cells
Y. Lee (1995)
Using NMR spectroscopy to assay phospholipases
Roberts MF. (1991)
The 61-kDa brain species has 529 residues, and, by limited proteolysis, a fully active and calmodulin-independent species of 36 kDa was isolated and found to comprise residues 136-450
Novack (1991)
10.1146/ANNUREV.NE.12.030189.001445
Cyclic GMP-activated conductance of retinal photoreceptor cells.
K. Yau (1989)
10.1016/S0960-9822(97)70090-3
Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization
W. C. Colley (1997)
10.1016/0021-9290(95)00093-3
Multiple cis-elements mediate shear stress-induced gene expression.
J. Shyy (1995)
10.1152/AJPRENAL.1996.270.1.F206
Nitric oxide inhibits ADH-stimulated osmotic water permeability in cortical collecting ducts.
N. Garcia (1996)
10.1042/BJ2520269
Cyclic GMP-dependent protein kinase phosphorylates phospholamban in isolated sarcoplasmic reticulum from cardiac and smooth muscle.
L. Raeymaekers (1988)
10.1038/366283A0
Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor cells
G. Lowe (1993)
10.1152/AJPRENAL.1996.270.6.F1027
Coordinate regulation of renal expression of nitric oxide synthase, renin, and angiotensinogen mRNA by dietary salt.
I. Singh (1996)
10.1126/science.270.5236.641
Activation of Cell-Specific Transcription by a Serine Phosphatase at the Site of Asymmetric Division
L. Duncan (1995)
10.1021/BI953084A
Dual inhibitory effect of gangliosides on phospholipase C-promoted fusion of lipidic vesicles.
G. Basañez (1996)
10.1042/BJ2600931
Discovery of a protein phosphatase activity encoded in the genome of bacteriophage lambda. Probable identity with open reading frame 221.
P. Cohen (1989)
The antibiotic puromycin was shown to be a competitive inhibitor of cyclic AMP phosphodiesterase and was useful in early studies
Cheung 1967a (1971)
10.1161/01.RES.77.4.803
cGMP-dependent protein kinase regulation of the L-type Ca2+ current in rat ventricular myocytes.
K. Sumii (1995)
10.1038/385725A0
Mechanism of odorant adaptation in the olfactory receptor cell
T. Kurahashi (1997)
10.1037/0033-295X.94.4.469
A psychomotor stimulant theory of addiction.
R. Wise (1987)
Factors affecting the ability of glycosylphosphatidylinositol-specific phospholipase D to degrade the membrane anchors of cell surface proteins
Kuo-Sen HUANGt
Chronic cocaine treatment decreases levels of the G protein subunits Gi alpha and Go alpha in discrete regions of rat brain.
E. Nestler (1990)
10.1177/17.8.505
CYCLIC 3',5'-NUCLEOTIDE PHOSPHODIESTERASE IN BRAIN
B. Breckenridge (1969)
Active sites of the cyclic GMP phosphodiesterase y-subunit of retinal rod outer segments
Moscow (1988)
10.1016/B978-0-444-81125-7.50008-6
CHAPTER 1 - Signalling through phospholipid breakdown
J. Exton (1990)
10.1038/362764A0
A new subunit of the cyclic nucleotide-gated cation channel in retinal rods
T. Chen (1993)
10.1074/jbc.271.28.16526
Phosphorylation and Activation of a cAMP-specific Phosphodiesterase by the cAMP-dependent Protein Kinase
C. Sette (1996)
10.1146/ANNUREV.PH.54.030192.001101
Role of cGMP and Ca2+ in vertebrate photoreceptor excitation and adaptation.
U. B. Kaupp (1992)
10.1016/0092-8674(89)90047-0
EGF induces tyrosine phosphorylation of phospholipase C-II: A potential mechanism for EGF receptor signaling
B. Margolis (1989)
10.1146/ANNUREV.BI.62.070193.004223
Function and regulation of ras.
D. Lowy (1993)
10.1111/J.1432-1033.1994.00447.X
Nitric oxide regulation of glyceraldehyde-3-phosphate dehydrogenase activity in Dictyostelium discoideum cells and lysates.
Y. Tao (1994)
10.1097/00001756-199101000-00001
High density cAMP-gated channels at the ciliary membrane in the olfactory receptor cell.
T. Kurahashi (1991)
10.1073/PNAS.87.1.293
Bovine cone photoreceptor cGMP phosphodiesterase structure deduced from a cDNA clone.
T. S. Li (1990)
10.1016/0006-2952(68)90185-8
Regional and subcellular distribution of adenyl cyclase and 3',5'-cyclic nucleotide phosphodiesterase in brain and pineal gland.
B. Weiss (1968)
10.1016/0005-2795(70)90195-9
Studies on phospholipase A and its zymogen from porcine pancreas. I. The complete amino acid sequence.
G. D. de Haas (1970)
10.1159/000159039
The nitric oxide synthase family of proteins.
W. Sessa (1994)
The binding of PP1 to these subunits
subunits Hubbard (1993)
10.1016/0092-8674(95)90408-5
Calcium signaling
D. Clapham (1995)
10.1073/PNAS.86.13.4922
Expression in bacteria of functional inhibitory subunit of retinal rod cGMP phosphodiesterase.
R. L. Brown (1989)
10.1038/364061A0
Role of H5 domain in determining pore diameter and ion permeation through cyclic nucleotide-gated channels
Evan H. Goulding (1993)
10.1073/PNAS.88.5.1788
Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells.
U. Foerstermann (1991)
10.1074/jbc.272.17.11011
Involvement of Phosphatidylcholine-specific Phospholipase C in Platelet-derived Growth Factor-induced Activation of the Mitogen-activated Protein Kinase Pathway in Rat-1 Fibroblasts*
M. V. van Dijk (1997)
10.1074/JBC.270.25.15175
Gα15 and Gα16 Couple a Wide Variety of Receptors to Phospholipase C (*)
S. Offermanns (1995)
[Mammalian non-pancreatic phospholipase A2: structure, characterization, and function].
I. Kudo (1992)
10.1016/S0065-3233(08)60638-5
Structure and catalytic mechanism of secretory phospholipases A2.
D. Scott (1994)
10.1128/MCB.10.9.4770
Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.
W. Burgess (1990)
10.1016/B978-0-12-185285-6.50008-7
[2] – Rat Brain Membrane-Bound Phospholipase D
M. Danin (1993)
homologous at the amino acid level, but there is 80-94% homology of a given NOS from different species
I II NOS (1994)
10.1021/JA00117A004
NITRIC OXIDE ENHANCES PROSTAGLANDIN-H SYNTHASE-1 ACTIVITY BY A HEME-INDEPENDENT MECHANISM : EVIDENCE IMPLICATING NITROSOTHIOLS
D. Hajjar (1995)
10.1021/BI00255A008
Structural consequences of histidine phosphorylation: NMR characterization of the phosphohistidine form of histidine-containing protein from Bacillus subtilis and Escherichia coli.
P. Rajagopal (1994)
Adenosine 3',5'-monophosphate in biological materials. II. The measurement of adenosine 3',5'-monophosphate in tissues and the role of the cyclic nucleotide in the lipolytic response of fat to epinephrine.
R. W. Butcher (1965)
10.1113/jphysiol.1978.sp012480
Adaptive properties of olfactory receptors analysed with odour pulses of varying durations.
T. Getchell (1978)
10.1016/0167-4889(90)90067-N
Hormone-sensitive lipase--a multipurpose enzyme in lipid metabolism.
S. J. Yeaman (1990)
10.1016/s0021-9258(18)52900-8
Phosphatidic acid, lysophosphatidic acid, and lipid A are inhibitors of glycosylphosphatidylinositol-specific phospholipase D. Specific inhibition of a phospholipase by product analogues?
M. Low (1993)
10.1016/s0021-9258(18)43893-8
Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not.
A. Hausladen (1994)
10.1016/s0021-9258(18)55344-8
Identification of the retinal cyclic GMP phosphodiesterase inhibitory gamma-subunit interaction sites on the catalytic alpha-subunit.
B. Oppert (1991)



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