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Structure, Function, And Antigenicity Of The Hemagglutinin Of Influenza Virus

S. A. Wharton, W. Weis, J. Skehel, D. Wiley
Published 1989 · Biology

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The major surface glycoprotein of influenza virus is hemagglutinin (HA). This chapter reviews the two major functions of HA: (1) its involvement in binding to receptors on cells before their infection, and (2) its role in the fusion of viral and endosomal membranes, necessary for the release of the viral genome into the cell. In addition, HA is the viral antigen that interacts with infectivity-neutralizing antibodies; alterations in the molecule enable the virus to escape immune surveillance and cause epidemics of disease. The nature of these changes in antigenicity is discussed.

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Jose M Galarza (2005)
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J. Pitt (2000)
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Influenza virus epidemiological surveillance in Argentina, 1987-1993, with molecular characterization of 1990 and 1993 isolates.
O. Uez (1998)
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M. Tang (2002)
On the dynamics of infectious diseases in non-homogeneous populations
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Histological and histochemical investigations of the pharyngeal jaw apparatus of a carp Cirrhinus mrigala.
Usha Kumari (2014)
Influenza virus antigens and ‘antigenic drift’
A. Hampson (2002)
Influenza virus genetics.
E. Brown (2000)
Varicella-zoster virus gE escape mutant VZV-MSP exhibits an accelerated cell-to-cell spread phenotype in both infected cell cultures and SCID-hu mice.
R. A. Santos (2000)
Histochemical analysis of glycoproteins in the secretory cells in the epidermis of the head skin of Indian Major Carp, Labeo rohita.
A. K. Rai (2012)
Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses
Seyhan Boyoglu-Barnum (2020)
and A Portela particles obtained from recombinant plasmids . acetyltransferase RNA into influenza virus-like Rescue of a synthetic chloramphenicol
I. Mena (1996)
Virus-like particle (VLP) vaccine conferred complete protection against a lethal influenza virus challenge.
Jose M Galarza (2005)
Insilico Prediction of Immunogenic Peptide of Hemagglutinin Protein in H1N1 Influenza Virus
Banpreet Gujral (2011)
Production and characterization of monoclonal antibodies to Brazilian isolates of bovine viral diarrhea virus.
L. C. Kreutz (2000)
A Perspective of Influenza Pandemics
John S. Oxford (2014)
Biology of the Sialic Acids
A. Rosenberg (1995)
Identification of Peptide Containing T Cell Epitope Of Hemagglutinin Protein In H5n1 Influenza Virus
N. Kumari (2014)
Histochemical characterization of glycoproteins in the buccal epithelium of the catfish, Rita rita.
M. Yashpal (2007)
Glycoproteins in the Epithelium of Lips and Associated Structures of a Hill Stream Fish Garra lamta (Cyprinidae, Cypriniformes): A Histochemical Investigation
S. Mittal (2008)
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