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Cerebral Cortical Control Of Deglutition
D. Vasant, S. Hamdy
Published 2013 · Medicine
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The human swallowing musculature is coordinated centrally through a multidimensional hierarchy of deglutative centres both in the cerebral cortex and brain stem. The cortex has an important role in initiation of the volitional swallow and has a role in all three phases of deglutition. Developments in technology, particularly functional brain imaging, have seen a fuller delineation of the human swallowing network and studies have shown that this system is adaptable to stimuli and subject to plastic change both to internal and external inputs. There is evidence to suggest cortical functional asymmetry, with a dominant swallowing hemisphere in healthy individuals, and when this is affected by stroke, with the non-dominant hemisphere clinically thought to be relevant in re-organisation and recovery of swallowing function. Finally, there is now considerable interest in neuromodulatory-based techniques in driving this brain re-organisation after cerebral injury.
This paper references
The role of the cerebral cortex in swallowing
R. Martin (2005)
Effect of esophageal acid exposure on the cortical swallowing network in healthy human subjects.
M. Kern (2009)
SOMATIC MOTOR AND SENSORY REPRESENTATION IN THE CEREBRAL CORTEX OF MAN AS STUDIED BY ELECTRICAL STIMULATION
W. Penfield (1937)
Discrete functional contributions of cerebral cortical foci in voluntary swallowing: a functional magnetic resonance imaging (fMRI) “Go, No-Go” study
Jillian A. Toogood (2004)
Cortical activation induced by intraoral stimulation with water in humans.
D. Zald (2000)
The organisation and re-organisation of human swallowing motor cortex.
S. Hamdy (2003)
Modulation of Activity in Swallowing Motor Cortex Following Esophageal Acidification: A Functional Magnetic Resonance Imaging Study
P. Paine (2007)
Unilateral suppression of pharyngeal motor cortex to repetitive transcranial magnetic stimulation reveals functional asymmetry in the hemispheric projections to human swallowing
S. Mistry (2007)
Distal and deglutitive inhibition in the rat esophagus: role of inhibitory neurotransmission in the nucleus tractus solitarii.
H. Dong (2000)
Lateralization of cortical function in swallowing: a functional MR imaging study.
K. Mosier (1999)
Stuttered swallowing: Electric stimulation of the right insula interferes with water swallowing. A case report
Peter Sörös (2011)
Dissociating the spatio-temporal characteristics of cortical neuronal activity associated with human volitional swallowing in the healthy adult brain
P. Furlong (2004)
Supranuclear Control of Swallowing
N. Leopold (2009)
Deglutitive inhibition affects both esophageal peristaltic amplitude and shortening.
G. Shi (2003)
The cortical paths for mastication and deglutition
F. Miller (1920)
Dysphagia in unilateral cerebral lesions
J. Meadows (1973)
Brain Stem Control of the Phases of Swallowing
I. M. Lang (2009)
Effects of atropine on the central mechanism of deglutition in anesthetized sheep
A. Car (2002)
Functional brain imaging of swallowing: An activation likelihood estimation meta‐analysis
Peter Sörös (2009)
Dysphagia in acute stroke.
C. Gordon (1987)
Functional oropharyngeal sensory disruption interferes with the cortical control of swallowing
I. Teismann (2007)
The topographic representation of esophageal motor function on the human cerebral cortex.
Q. Aziz (1996)
Recovery of swallowing after dysphagic stroke relates to functional reorganization in the intact motor cortex.
S. Hamdy (1998)
The neurobiology of swallowing and dysphagia.
A. Miller (2008)
Normal Swallowing and Functional Magnetic Resonance Imaging: A Systematic Review
I. Humbert (2007)
Cortical Regulation During the Early Stage of Initiation of Voluntary Swallowing in Humans
Y. Watanabe (2003)
SOME OBSERVATIONS ON THE BUCCO‐PHARYNGEAL STAGE OF REFLEX DEGLUTITION IN THE CAT
F. R. Miller (1915)
Task-dependent differences in corticobulbar excitability of the submental motor projections: Implications for neural control of swallowing
S. Doeltgen (2011)
Volitional control of food transport and bolus formation during feeding
J. Palmer (2007)
Dysphagia After Stroke: Incidence, Diagnosis, and Pulmonary Complications
R. Martino (2005)
Enhancing effects of flavored nutritive stimuli on cortical swallowing network activity.
A. Babaei (2010)
Physiology and Pathophysiology of the Swallowing Area of Human Motor Cortex
S. Hamdy (2001)
Neuroimaging evidence for cortical involvement in the preparation and in the act of swallowing
R. Dziewas (2003)
Cerebral cortical processing of swallowing in older adults
R. Martin (2006)
Driving Plasticity in Human Adult Motor Cortex Is Associated with Improved Motor Function after Brain Injury
C. Fraser (2002)
The natural history and functional consequences of dysphagia after hemispheric stroke.
D. Barer (1989)
Neurophysiology of swallowing
C. Ertekin (2003)
Cortical activation during human volitional swallowing: an event-related fMRI study.
S. Hamdy (1999)
Cerebral cortical representation of reflexive and volitional swallowing in humans.
M. Kern (2001)
Magnetoencephalographic Study of the Starting Point of Voluntary Swallowing
S. Abe (2003)
Modulation of human cortical swallowing motor pathways after pleasant and aversive taste stimuli.
S. Mistry (2006)
Sensory Input Pathways and Mechanisms in Swallowing: A Review
C. Steele (2010)
Stimulation of the chewing area of the cerebral cortex induces inhibitory effects upon swallowing in sheep
Mohamed Lamkadem (1999)
Neural control of feeding and swallowing.
S. Mistry (2008)
An electrophysiological and morphological study of esophageal motoneurons in rats.
B. Kruszewska (1994)
The cortical topography of human swallowing musculature in health and disease
S. Hamdy (1996)
Cerebral areas processing swallowing and tongue movement are overlapping but distinct: a functional magnetic resonance imaging study.
R. Martin (2004)
Role of cerebral cortex in the control of swallowing
S. Hamdy (2006)
Neurophysiology of swallowing: Effects of age and bolus type
I. Humbert (2009)
Adjunctive functional pharyngeal electrical stimulation reverses swallowing disability after brain lesions.
V. Jayasekeran (2010)
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Assessment and behavioural modulation of the upper oesophageal sphincter in healthy swallowing.
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Neuroanatomy of Voice and Swallowing
N. Y. Li-Jessen (2020)
The Relationship Between Lesion Localization and Dysphagia in Acute Stroke
S. Daniels (2017)
Tempo de trânsito oral e lateralidade da lesão cerebral no acidente vascular encefálico
Thaís Coelho Alves (2017)
Relationship between pharyngeal response time and lateralized brain lesion in stroke
Thaís Coelho Alves (2019)
Characterization of swallow modulation in response to bolus volume in healthy subjects accounting for catheter diameter
L. Ferris (2018)