Online citations, reference lists, and bibliographies.

Craniopharyngioma: Current Classification, Management, And Future Directions

Z. Habibi, Deya Abu Reesh, J. Rutka
Published 2019 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
Craniopharyngioma is one of the most challenging brain tumors, located in sellar/suprasellar region in close proximity to the optic apparatus and hypothalamus. Although histologically low grade, the tumor can be locally aggressive and serve as a source of considerable morbidity due to compression and/or adherence to nearby structures. Due to its unpredictable natural history and long-term sequelae of various treatments, the ideal management of craniopharyngioma has been constantly debated over several generations of neurosurgeons. Many clinical series have advocated for gross total resection (GTR) to reduce the risk of tumor recurrence, while craniopharyngiomas are considered unresectable lesions by other authors and a recommendation for a more conservative neurosurgical approach followed by radiation therapy or intracystic treatment is given. The ongoing debate regarding the use of “aggressive” or “less invasive” surgical approaches has at least the benefit of suggesting that treatment plans should be customized to the individual patient and tumor characteristics. In this way, the maximum, safe neurosurgical procedure can be performed while minimizing untoward patient morbidity.
This paper references
10.1097/00006123-199702000-00006
Cystic craniopharyngioma: long-term results after intracavitary irradiation with stereotactically applied colloidal beta-emitting radioactive sources.
J. Voges (1997)
10.1159/000113019
Childhood Craniopharyngioma
H. Müller (2008)
10.3171/2009.5.PEDS09106
Modified orbitozygomatic craniotomy for craniopharyngioma resection in children.
Kiarash J Golshani (2009)
10.1016/S1091-8531(99)70047-9
Visual recovery after a year of craniopharyngioma-related amaurosis: report of a nine-year-old child and a review of pathophysiologic mechanisms.
K. Stark (1999)
10.3171/PED.2007.106.1.3
Pediatric craniopharyngiomas: classification and treatment according to the degree of hypothalamic involvement.
S. Puget (2007)
10.1016/S0022-3476(73)80369-5
Craniopharyngioma in children.
M. Banna (1973)
10.1007/s003810050224
Perioperative fluid and electrolyte management in children undergoing surgery for craniopharyngioma A 10-year experience in a single institution
T. Lehrnbecher (1998)
Craniopharyngioma: ophthalmological aspects at diagnosis.
S. Defoort-Dhellemmes (2006)
10.3171/JNS/2008/108/4/0715
Expanded endonasal approach, a fully endoscopic transnasal approach for the resection of midline suprasellar craniopharyngiomas: a new classification based on the infundibulum.
A. Kassam (2008)
10.1227/01.NEU.0000335786.10968.2F
Management of cystic craniopharyngiomas with stereotactic endocavitary irradiation using colloidal 186 Re
M. Smyth (2008)
10.3171/2016.9.FOCUS16325
Diagnosis and management of craniopharyngiomas in the era of genomics and targeted therapy.
J. C. Martinez-Gutierrez (2016)
10.3171/2016.8.FOCUS16307
Molecular pathology of adamantinomatous craniopharyngioma: review and opportunities for practice.
J. Apps (2016)
10.3171/2016.9.FOCUS16211
Aggressive surgery based on an anatomical subclassification of craniopharyngiomas.
H. Morisako (2016)
10.1007/s11060-016-2147-4
Microsurgical removal of craniopharyngioma: endoscopic and transcranial techniques for complication avoidance
Saira Alli (2016)
10.1586/14737175.2016.1166959
Risk-adapted treatment and follow-up management in childhood-onset craniopharyngioma
H. Müller (2016)
10.3233/CBM-140397
High expression levels of CXCL12 and CXCR4 predict recurrence of adamanti-nomatous craniopharyngiomas in children.
J. Gong (2014)
10.1016/S0360-3016(02)04597-2
Patterns of patient movement during frameless image-guided radiosurgery.
M. Murphy (2003)
10.1007/s11060-011-0540-6
Incidence of craniopharyngioma in Denmark (n = 189) and estimated world incidence of craniopharyngioma in children and adults
E. H. Nielsen (2011)
10.1016/j.pediatrneurol.2013.09.003
A review of childhood and adolescent craniopharyngiomas with particular attention to hypothalamic obesity.
Amy Rosenfeld (2014)
10.1016/s1042-3680(18)30628-4
Suprasellar and sellar tumors in childhood and adolescence.
J. Rutka (1992)
10.1038/nri3845
Type I interferons in anticancer immunity
L. Zitvogel (2015)
10.3171/2010.1.FOCUS09310
Craniopharyngiomas: intratumoral chemotherapy with interferon-alpha: a multicenter preliminary study with 60 cases.
S. Cavalheiro (2010)
10.3171/2013.9.JNS122133
Microsurgical resection of extensive craniopharyngiomas using a frontolateral approach: operative technique and outcome.
V. Gerganov (2014)
10.1227/00006123-198209000-00008
Craniopharyngiomas in children.
P. Carmel (1982)
10.1007/s10143-017-0933-x
Predicting pituitary stalk position by in vivo visualization of the hypothalamo-hypophyseal tract in craniopharyngioma using diffusion tensor imaging tractography
F. Wang (2017)
10.1016/J.BRAINDEV.2007.07.011
Comparison of hypothalamopituitary axis dysfunction of intrasellar and third ventricular craniopharyngiomas in children
Yi-Yen Lee (2008)
10.1097/01.MLG.0000234933.37779.E4
A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap.
G. Hadad (2006)
10.1007/s11060-014-1600-5
The ophthalmic natural history of paediatric craniopharyngioma: a long-term review
E. Drimtzias (2014)
The pre-operative endocrine assessment of craniopharyngiomas.
N. Hopper (2006)
10.1530/EJE-15-0422
Nonalcoholic fatty liver disease and fatigue in long-term survivors of childhood-onset craniopharyngioma.
A. Hoffmann (2015)
10.1016/J.RADONC.2006.11.005
Fractionated stereotactic conformal radiotherapy following conservative surgery in the control of craniopharyngiomas.
G. Minniti (2007)
10.3171/2010.1.FOCUS09309
Surgical nuances for removal of retrochiasmatic craniopharyngiomas via the transbasal subfrontal translamina terminalis approach.
J. Liu (2010)
10.3389/fendo.2012.00039
Intracystic Therapies for Cystic Craniopharyngioma in Childhood
U. Bartels (2012)
10.3171/JNS.1998.88.1.0043
Dose-response tolerance of the visual pathways and cranial nerves of the cavernous sinus to stereotactic radiosurgery.
K. Leber (1998)
10.3171/2010.2.FOCUS09304
Craniopharyngioma Clinical Status Scale: a standardized metric of preoperative function and posttreatment outcome.
R. Elliott (2010)
10.1097/00006123-200210001-00009
The sellar region.
A. Rhoton (2002)
10.1159/000120855
Pathology of craniopharyngiomas: clinical import of pathological findings.
D. Miller (1994)
10.1016/S0140-6736(00)04006-X
Association between premature mortality and hypopituitarism
J. Tomlinson (2001)
10.1097/MED.0000000000000214
Craniopharyngioma and hypothalamic injury: latest insights into consequent eating disorders and obesity
H. Müller (2016)
10.1227/01.NEU.0000335786.10968.2F
MANAGEMENT OF CYSTIC CRANIOPHARYNGIOMAS WITH STEREOTACTIC ENDOCAVITARY IRRADIATION USING COLLOIDAL 186: A RETROSPECTIVE STUDY OF 48 CONSECUTIVE PATIENTS
S. Derrey (2008)
10.1093/neuonc/noy035
Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma
S. Coy (2018)
10.1159/000120693
Radical resections of childhood craniopharyngiomas.
T. Tomita (1993)
10.1007/s11060-018-2776-x
The diagnostic value of preoperative inflammatory markers in craniopharyngioma: a multicenter cohort study
M. Chen (2018)
10.1007/s00428-018-2323-3
Molecular defects in BRAF wild-type ameloblastomas and craniopharyngiomas—differences in mutation profiles in epithelial-derived oropharyngeal neoplasms
S. Bartels (2018)
10.1159/000368401
Water and Electrolyte Disorders at Long-Term Post-Treatment Follow-Up in Paediatric Patients with Suprasellar Tumours Include Unexpected Persistent Cerebral Salt-Wasting Syndrome
Laura G González Briceño (2014)
10.1016/j.wneu.2017.11.012
Preoperative Assessment of Craniopharyngioma Adherence: Magnetic Resonance Imaging Findings Correlated with the Severity of Tumor Attachment to the Hypothalamus.
R. Prieto (2018)
10.1530/EJE-15-0957
ENDOCRINE TUMORS: BRAF V600E mutations in papillary craniopharyngioma.
P. Brastianos (2016)
10.3171/jns.1990.73.1.0003
Total removal of craniopharyngiomas. Approaches and long-term results in 144 patients.
M. Yașargil (1990)
10.1016/J.IJROBP.2005.09.034
Combined proton and photon irradiation for craniopharyngioma: long-term results of the early cohort of patients treated at Harvard Cyclotron Laboratory and Massachusetts General Hospital.
M. Fitzek (2006)
10.1007/s00381-005-1190-9
The pathogenesis of craniopharyngiomas
V. Prabhu (2005)
10.3171/JNS.2002.97.1.0003
Craniopharyngioma in adults and children: a study of 122 surgical cases.
R. van Effenterre (2002)
10.3171/2014.10.PEDS14384
Recurrent craniopharyngioma after conformal radiation in children and the burden of treatment.
P. Klimo (2015)
10.1007/BF00165157
Therapeutic benefits of combination chemotherapy with vincristine, BCNU, and procarbazine on recurrent cystic craniopharyngioma
A. Bremer (1984)
10.3171/2010.2.FOCUS09311
The role of radiosurgery in the treatment of craniopharyngiomas.
A. Veeravagu (2010)
10.1038/ng.2868
Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas
P. Brastianos (2014)
10.1016/S0090-3019(02)00701-2
Surgical management of colloid cyst of the third ventricle--a study of 105 cases.
K. Desai (2002)
10.1227/00006123-199412000-00001
Craniopharyngiomas: A clinicopathological analysis of factors predictive of recurrence and functional outcome
H. Weiner (1994)
10.1097/00006123-200111000-00005
Memory Deficits among Children with Craniopharyngiomas
S. Carpentieri (2001)
10.1016/j.clineuro.2007.10.013
Craniopharyngioma: Surgical experience of 309 cases in China
X. Shi (2008)
Fractionated Proton Radiation Treatment for Pediatric Craniopharyngioma: Preliminary Report
Q. T. Luu (2006)
10.1111/j.1365-2265.2005.02231.x
Craniopharyngiomas in children and adults: systematic analysis of 121 cases with long‐term follow‐up
N. Karavitaki (2005)
10.3171/PED-07/10/318
Neuroradiological findings of bleomycin leakage in cystic craniopharyngioma. Report of three cases.
L. Lafay-Cousin (2007)
10.3171/jns.1995.83.2.0206
Papillary craniopharyngioma: a clinicopathological study of 48 cases.
T. Crotty (1995)
10.1007/s00381-005-1246-x
Endocrine manifestations of craniopharyngioma
I. Halac (2005)
10.3171/SPI.2002.97.1.0001
Atraumatic bloodless removal of intramedullary hemangioblastomas of the spinal cord.
L. Malis (2002)
10.3171/jns.1998.89.4.0547
The descriptive epidemiology of craniopharyngioma.
G. Bunin (1997)
10.1093/neuonc/not026
Trends in treatment and outcomes of pediatric craniopharyngioma, 1975-2011.
M. Cohen (2013)
10.1016/S1090-3798(98)80040-8
Chemotherapy with Adriamycin (doxorubicin) and CCNU (lomustine) in four children with recurrent craniopharyngioma.
R. J. Lippens (1998)
10.1055/s-0037-1621738
Pediatric Craniopharyngiomas: A Primer for the Skull Base Surgeon
C. Graffeo (2018)
10.1186/1824-7288-37-38
Obesity and craniopharyngioma
L. Iughetti (2011)
10.1530/EJE-18-0081
Microstructural white matter alterations and hippocampal volumes are associated with cognitive deficits in craniopharyngioma
S. Fjalldal (2018)
10.1016/j.radonc.2014.11.035
Long-term disease control and toxicity outcomes following surgery and intensity modulated radiation therapy (IMRT) in pediatric craniopharyngioma.
Brad J. Greenfield (2015)
10.1016/j.ijrobp.2014.05.051
Proton beam therapy versus conformal photon radiation therapy for childhood craniopharyngioma: multi-institutional analysis of outcomes, cyst dynamics, and toxicity.
A. Bishop (2014)
10.3171/JNS.1999.91.5.0831
Expression of vascular permeability factor in craniopharyngioma.
J. Vaquero (1999)
Craniopharyngioma in adults.
M. Banna (1973)
10.1017/S0012162204000374
Outcome of craniopharyngioma in children: long-term complications and quality of life.
A. Poretti (2004)
10.3171/2016.9.FOCUS16298
A quantitative analysis of craniopharyngioma cyst expansion during and after radiation therapy and surgical implications.
Kelly Lamiman (2016)
10.1007/s00381-010-1245-4
The role of inflammation in the genesis of the cystic component of craniopharyngiomas
B. Pettorini (2010)
10.1210/jc.2013-2000
Hypothalamic involvement predicts cognitive performance and psychosocial health in long-term survivors of childhood craniopharyngioma.
S. Fjalldal (2013)
10.1002/9780470479216.CORPSY1039
Wide‐Range Assessment of Memory and Learning
W. Adams (2010)
10.1111/j.1651-2227.1988.tb10705.x
Children with Craniopharyngioma
R. Sorva (1988)
10.1111/dom.12928
A randomized, placebo‐controlled trial of beloranib for the treatment of hypothalamic injury‐associated obesity
Ashley H Shoemaker (2017)
10.1111/j.1365-2559.2004.02029.x
Expression of enamel proteins and LEF1 in adamantinomatous craniopharyngioma: evidence for its odontogenic epithelial differentiation
S. Sekine (2004)



Semantic Scholar Logo Some data provided by SemanticScholar