Please confirm you are human (Sign Up for free to never see this)
← Back to Search
The Commercialization Of Medical Nanotechnology For Medical Applications
D. W. Hobson
Published 2016 · Business
Save to my Library
Download PDFAnalyze on Scholarcy
The potential for nanotechnology to advance medical science has been demonstrated and is increasing as the ability to manufacture and combine an ever expanding selection of nanotechnologies creates a wide variety of opportunities. Mechanisms for the commercialization of these “nanomedical” products have met with both success and failure but always with valuable lessons to apply toward advancing the future for the technology platforms. Nanotechnology applications in medicine are already having a significant impact on marketed products as well as increasing the number of commercially viable products in both pharmaceutical and medical device pipelines directed toward a wide variety of therapeutic applications. Commercial uses of nanotechnology in the development and formulation of new pharmaceuticals as well as incorporation into the designs of medical devices are increasing and hold much promise for commercial success. Regulatory agencies and legal firms worldwide are cautiously examining some aspects of many nanotechnology products toward demonstrating sustainable histories of safety and efficacy in these various medical applications. Approaches that have been successful in commercializing approved and currently marketed nanomedical products have met with many challenges and have identified and resolved critical issues that could have prevented or hindered market entry. The commercial path becoming increasingly better defined for new and developing products that hold much promise to significantly improve medicine in areas such as nanomaterial-enabled pharmaceuticals, targeted nanomolecular therapeutics and diagnostics, nanobrachytherapy agents and nano-enabled medical devices.
This paper references
The bactericidal effect of silver nanoparticles.
J. R. Morones (2005)
Recent advancements in nanotechnological strategies in selection, design and delivery of biomolecules for skin regeneration.
Purna Sai Korrapati (2016)
Three-Dimensional Printing Surgical Applications
Ahmad Alali (2015)
Protecting new ideas and inventions in nanomedicine with patents.
R. Bawa (2005)
Cardiotoxicity reduction induced by halofantrine entrapped in nanocapsule devices.
E. A. Leite (2007)
Determining the relationship between nanoparticle characteristics and immunotoxicity: key challenges and approaches.
C. David (2016)
Biotechnology as a route to nanotechnology
Stimuli-responsive poly(N-isopropyl acrylamide)-co-tyrosine@gadolinium: Iron oxide nanoparticle-based nanotheranostic for cancer diagnosis and treatment.
E. Roy (2016)
Recent insights in nanotechnology-based drugs and formulations designed for effective anti-cancer therapy
Ewelina Piktel (2016)
The pathway to commercialization for nanomedicine.
T. Flynn (2005)
Patents and nanomedicine.
R. Bawa (2007)
FDA's Approach to Regulation of Products of Nanotechnology
M. Hamburg (2012)
Patenting of nanopharmaceuticals in drug delivery: no small issue.
L. D. du Toit (2007)
SCCP (Scientific Committee on Consumer Products) / SCHER (Scientific Committee on Health& Environment Risks) / SCENIHR (Scientific Committee on Emerging and Newly- Identified Health Risks) opinion on: Risk assessment methodologies and approaches for genotoxic and carcinogenic substances
H. Autrup (2009)
Nanomedicines: addressing the scientific and regulatory gap
S. Tinkle (2014)
Tissue growth into three-dimensional composite scaffolds with controlled micro-features and nanotopographical surfaces.
E. Tamjid (2013)
Commercialization of nanotechnology.
D. W. Hobson (2009)
Applications of nanoparticles for diagnosis and therapy of cancer.
S. Baetke (2015)
Nanoprobes for two-photon excitation time-resolved imaging of living animals: In situ analysis of tumor-targeting dynamics of nanocarriers.
W. Yang (2016)
Recent Trends of Biocompatible and Biodegradable Nanoparticles in Drug Delivery: A Review.
D. Sundar (2016)
Liposome encapsulation improves efficacy of betamethasone dipropionate in atopic eczema but not in psoriasis vulgaris
H. C. Korting (2004)
The potential risks of nanomaterials: a review carried out for ECETOC
P. Borm (2006)
An antibacterial coating based on a polymer/sol-gel hybrid matrix loaded with silver nanoparticles
P. Rivero (2011)
Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date
Daniel Bobo (2016)
Nonobatteries: decreasing size power sources for growing technologies.
D. Lowy (2008)
Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe
Evan Phillips (2014)
Biofilm on dental implants: a review of the literature.
K. Subramani (2009)
Nanomaterial toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput screening.
A. Nel (2013)
Cardiovascular nanomedicine: a posse ad esse.
B. Godin (2012)
Multifunctional aptamer-based nanoparticles for targeted drug delivery to circumvent cancer resistance.
J. Liu (2016)
Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction
M. Santoso (2016)
Nanomedicine and Tissue Engineering
C. Sudhakar (2015)
A new framework for determining critical success/failure factors in projects
W. Belassi (1996)
Nanosilver as a new generation of nanoproduct in biomedical applications.
K. Chaloupka (2010)
Maximum Likelihood Estimation for an Innovation Diffusion Model of New Product Acceptance
David C. Schmittlein (1982)
Self nanoprecipitating preconcentrate of tamoxifen citrate for enhanced bioavailability.
Sonali V Kapse (2012)
Directed migration of cancer cells by the graded texture of the underlying matrix
Jinseok Park (2016)
The impact of effective patents on future innovations in nanomedicine.
Rita Bosetti (2012)
Has nanomedicine lived up to its promise?
S. Venkatraman (2014)
Nanocrystalline hydroxyapatite-based material already contributes to implant stability after 3 months: a clinical and radiologic 3-year follow-up investigation.
S. Ghanaati (2014)
Nanoparticles applied to antineoplastic agents: a patent landscape.
I. Fierro (2014)
Progress in the Development of Nanotheranostic Systems
H. Cui (2016)
The Nanopharmacology and Nanotoxicology of Nanomaterials: New Opportunities and Challenges.
A. Radomska (2016)
Trends in nanotechnology patents applied to the health sector.
A. M. S. Antunes (2012)
Blood clearance and organ distribution of intravenously administered polymethacrylic nanoparticles in mice.
A. Rolland (1989)
Biodegradable polymer nanocapsules containing a sunscreen agent: preparation and photoprotection.
R. Alvarez-Román (2001)
An integrated optical interferometric nanodevice based on silicon technology for biosensor applications
Francisco Prieto (2003)
Grey Goo on the Skin? Nanotechnology, Cosmetic and Sunscreen Safety
G. Nohynek (2007)
Guidance on the Determination of Potential Health Effects of Nanomaterials Used in Medical Devices
A. Proykova (2014)
A novel therapeutic design of microporous-structured biopolymer scaffolds for drug loading and delivery.
B. Dorj (2014)
At the cutting edge: applications and perspectives of laser nanosurgery in cell biology
Paolo Ronchi (2012)
A New Polymer Concept for Coating of Vascular Stents Using PTFEP (poly(bis(trifluoroethoxy)phosphazene) to Reduce Thrombogenicity and Late In-Stent Stenosis
G. Richter (2005)
New advances in electrochemical biosensors for the detection of toxins: Nanomaterials, magnetic beads and microfluidics systems. A review.
Laia Reverté (2016)
Design strategies of hybrid metallic nanoparticles for theragnostic applications.
J. Gautier (2013)
Dealing with nanosafety around the globe-Regulation vs. innovation.
M. Wacker (2016)
Cancer nanomedicines: so many papers and so few drugs!
Vincent J Venditto (2013)
Toxicology of antimicrobial nanoparticles for prosthetic devices
R. E. Nuñez-Anita (2014)
Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy.
Edgar Pérez-Herrero (2015)
Electrochemical biosensors based on nanofibres for cardiac biomarker detection: A comprehensive review.
B. Rezaei (2016)
Choosing a Wound Dressing Based on Common Wound Characteristics.
Ganary Dabiri (2016)
Nanotechnology-Based Photodynamic Therapy: Concepts, Advances, and Perspectives.
Tarun Garg (2015)
Intestinal absorption of insulin nanoparticles: contribution of M cells.
M. A. Lopes (2014)
Gelatin coated hybrid lipid nanoparticles for oral delivery of amphotericin B.
S. Jain (2012)
Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter
Graphene-based nanomaterials for bioimaging.
J. Lin (2016)
Biocompatibility of silver containing silica films on Bioverit® II middle ear prostheses in rabbits
Franziska Duda (2015)
Changes in cardiopulmonary function induced by nanoparticles.
Erin E Mann (2012)
Application of nanotechnology in cancer: a review
S. Kolhe (2012)
Transforming Nanomedicines From Lab Scale Production to Novel Clinical Modality.
Dalit Landesman-Milo (2016)
High-Content Screening for Assessing Nanomaterial Toxicity.
Lingling Huo (2015)
Antimicrobial Polymers with Metal Nanoparticles
H. Palza (2015)
Phytantriol Based “Stealth” Lyotropic Liquid Crystalline Nanoparticles for Improved Antitumor Efficacy and Reduced Toxicity of Docetaxel
S. Jain (2015)
Therapeutic gold, silver, and platinum nanoparticles.
M. Yamada (2015)
Particle uptake by Peyer’s patches: a pathway for drug and vaccine delivery
Monjed Shakweh (2004)
Prospects and developments in cell and embryo laser nanosurgery.
Vikram Kohli (2009)
Efficient Targeting of Adipose Tissue Macrophages in Obesity with Polysaccharide Nanocarriers.
Liang Ma (2016)
Nanocoating of titanium implant surfaces with organic molecules. Polysaccharides including glycosaminoglycans.
K. Gurzawska (2012)
A primary battery-on-a-chip using monolayer graphene.
R. M. Iost (2016)
Safety assessment of nanoparticles for drug delivery by means of classic in vitro assays and beyond
Stefan Lorscheidt (2016)
Three-dimensional printing and the surgeon.
A. Mel (2016)
Issues and concerns in nanotech product development and its commercialization.
I. P. Kaur (2014)
Dendrimer-based nanocarriers: a versatile platform for drug delivery.
Hao-jui Hsu (2017)
Assessment of the oxidative potential of nanoparticles by the cytochrome c assay: assay improvement and development of a high-throughput method to predict the toxicity of nanoparticles
M. Delaval (2016)
Traditional Therapies for Skin Wound Healing.
Rúben F. Pereira (2016)
Nanomedicine for targeted cancer therapy: towards the overcoming of drug resistance.
Alina Shapira (2011)
Silver and nanoparticles of silver in wound dressings: a review of efficacy and safety.
L. Wilkinson (2011)
Understanding Nanomedicine: An Introductory Textbook
Rob Burgess (2012)
Optical nanobiosensor for monitoring an apoptotic signaling process in a single living cell following photodynamic therapy.
P. Kasili (2005)
Nanotechnology and regenerative therapeutics in plastic surgery: The next frontier.
A. Tan (2016)
Nanotechnology Patent Procurement and Litigation in Europe
Hanna R. Laure´n (2012)
Enhanced Antitumor Efficacy and Reduced Toxicity of Docetaxel Loaded Estradiol Functionalized Stealth Polymeric Nanoparticles.
S. Jain (2015)
Therapeutic nanosystems for oral administration of insulin.
F. A. do Carmo (2014)
Techniques for Investigating Molecular Toxicology of Nanomaterials.
Y. Wang (2016)
Nanocoating for biomolecule delivery using layer-by-layer self-assembly.
M. Keeney (2015)
Nanotechnology-Based Biosensors and Diagnostics: Technology Push versus Industrial/Healthcare Requirements
S. K. Vashist (2012)
Nanoscale Science and Engineering: Unifying and Transforming Tools
M. Roco (2004)
A nanotechnology-based delivery system: Nanobots. Novel vehicles for molecular medicine.
T. Jacob (2011)
This paper is referenced by
Nanomaterials engineering for drug delivery: a hybridization approach.
M. Mohammadi (2017)
Integrated Safety and Risk Assessment for Medical Devices and Combination Products
S. Gad (2019)