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Methods And Strategies For Radiation Dose Optimization — And Reduction — In MDCT With Special Focus On The Image Quality
Published 2007 · Medicine
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The danger of ionizing radiation is related to the potential long-term risk of carcinogenesis. In Chapters. 1 and 2 of this book, Chadwick and Cohen have detailed how this risk is evaluated and considered in the field of low-level radiation in which diagnostic imaging (including CT) in comprised. The linear no threshold (LNT) theory of carcinogenesis is based on the risk of hereditary mutations deriving from cellular effects in germ cells. This theory considers that the cancer risk is linearly proportional to the dose at high doses as well as at low doses, from zero dose up. On the other hand, failure of the LNT theory is based on series of investigations showing that there is substantial evidence that low-level radiation does not have any carcinogenic effect and may even be protective against cancer, a view known as “hormesis”.