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Calculation Of O2 Saturation And Of The Oxyhemoglobin Dissociation Curve For Different Species, Using A New Programmable Pocket Calculator
Published 2004 · Chemistry, Medicine
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SummaryThe degree of O2 saturation and different data of acid-base status are determined frompO2, pH, andpCO2 values by a programmable pocket calculator. Since the operating program should be usable for different species and also in the range of very low O2 saturations, obviously the usual Hill equation for calculating the oxygen dissociation curve of hemoglobin is not applicable; the same is true in some cases for the Adair equation. Thus a 3-fold subdivision of the dissociation curve was undertaken and programmed. Suitable programs for several species could be established despite the limited number of program steps in the new calculator, giving systematic deviations in calculated O2 saturations of ≤ ± 0.9 saturation percent over the full range of dissociation curves. A reverse procedure for calculation ofpO2 from saturation is added. In situations wherepCO2 or base excess are not known or only estimated, limits of the arising error are stated. In the acid-base-program 7 parameters are evaluated partially using empirical formulae derived from nomograms. The programmable pocket calculator offers advantages of small size, economy, and independence of line voltage compared to much more spacious units and a precision equal or superior to nomograms.