Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

Transmission Near-Field Scanning Optical Microscopy Investigation On Cellular Uptake Behavior Of Iron Oxide Nanoparticles

Y. Zhang, Jennifer Reiber Kyle, Miro Penchev, Vahid R. Yazdanpanah, J. Yu, Y. Li, M. Yang, G. Budak, E. Ozbay, M. Ozkan, C. Ozkan
Published 2012 · Materials Science

Save to my Library
Download PDF
Analyze on Scholarcy
Cellular uptake behavior of iron oxide nanoparticles is investigated using a transmission near-field scanning optical microscopy (NSOM) without the need of fluorescent labeling. By using the transmission NSOM system, we could simultaneously explore the near-field optical analysis of the cell interior and record the topographic information of the cell surface. The cell endocytosis of iron oxide nanoparticles by normal breast MCF10A cells is first studied by this transmission NSOM system, and this dual functional nanoscale-resolution microscopy shows the capability of mapping the spatial localization of nanoparticles in/outside cell surface without the need of fluorescence labeling. Nanoscale optical signature patterns for iron oxide nanoparticle-loaded vesicles inside the cells were observed and analyzed.
This paper references
Fluorophore‐Conjugated Iron Oxide Nanoparticle Labeling and Analysis of Engrafting Human Hematopoietic Stem Cells
Dustin J. Maxwell (2008)
The Cell: A Molecular Approach
Sreeurpa Ray (2014)
From images to interactions: high-resolution phase imaging in tapping-mode atomic force microscopy.
M. Stark (2001)
Near-Field Optics: Microscopy, Spectroscopy, and Surface Modification Beyond the Diffraction Limit
E. Betzig (1992)
Size-dependent cellular uptake and expulsion of single-walled carbon nanotubes: single particle tracking and a generic uptake model for nanoparticles.
Hong Jin (2009)
Cell biology beyond the diffraction limit: near-field scanning optical microscopy.
F. de Lange (2001)
Near‐field scanning optical microscopy in liquid for high resolution single molecule detection on dendritic cells
M. Koopman (2004)
Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells.
B. Chithrani (2006)
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications.
A. Gupta (2005)
Proton transverse relaxation rate (R2) images of iron‐loaded liver tissuepping local tissue iron concentrations with MRI
Paul R. Clark (2003)
T Enderle (1998)
Physical limits of hyperthermia using magnetite fine particles
R. Hergt (1998)
Antibiofouling polymer-coated superparamagnetic iron oxide nanoparticles as potential magnetic resonance contrast agents for in vivo cancer imaging.
Haerim Lee (2006)
The molecular approach
D. Strosberg (2005)
Spectroscopy, imaging, and probes
H. Mader (2008)
Handbook of Biological Confocal Microscopy
J. Pawley (1990)
Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating.
C. Wilhelm (2003)
Revealing the topography of cellular membrane domains by combined atomic force microscopy/fluorescence imaging.
D. Z. Frankel (2006)
Synthesis of Complexable Fluorescent Superparamagnetic Iron Oxide Nanoparticles (FL SPIONs) and Cell Labeling for Clinical Application.
Jaeho Lee (2008)
Domains in cell plasma membranes investigated by near-field scanning optical microscopy.
J. Hwang (1998)
Fluorescence methods and applications: spectroscopy, imaging, and probes; [this volume is the result of the 10th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging, and Probes held September 9 - 12, 2007 at the Salzburg Congress Center, Salzburg, Austria]
O. S. Wolfbeis (2008)
Near-field fluorescence microscopy of cells.
T. Enderle (1998)
Near-field scanning fluorescence microscopy study of ion channel clusters in cardiac myocyte membranes.
A. Ianoul (2004)
Interaction of Anionic Superparamagnetic Nanoparticles with Cells: Kinetic Analyses of Membrane Adsorption and Subsequent Internalization
C. Wilhelm (2002)
Labeling TiO2 nanoparticles with dyes for optical fluorescence microscopy and determination of TiO2-DNA nanoconjugate stability.
K. Thurn (2009)

This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar