Please confirm you are human (Sign Up for free to never see this)
← Back to Search
Laccases And Their Occurrence In Prokaryotes
Published 2003 · Biology, Medicine
Save to my Library
Download PDFAnalyze on Scholarcy
Laccases are copper-containing proteins that require O2 to oxidize phenols, polyphenols, aromatic amines, and different non-phenolic substrates by one-electron transfer, resulting in the formation of reactive radicals. Although their specific physiological functions are not completely understood, there are several indications that laccases are involved in the morphogenesis of microorganisms (e.g., fungal spore development, melanization) and in the formation and/or degradation of complex organic substances such as lignin or humic matter. Owing to their high relative non-specific oxidation capacity, laccases are useful biocatalysts for diverse biotechnological applications. To date, laccases have been found only in eukaryotes (fungi, plants); however, databank searches and experimental data now provide evidence for their distribution in prokaryotes. This survey shows that laccase-like enzymes occur in many gram-negative and gram-positive bacteria. Corresponding genes have been found in prokaryotes that are thought to have branched off early during evolution, e.g., the extremely thermophilic Aquifex aeolicus and the archaeon Pyrobaculum aerophilum. Phylogenetically, the enzymes are members of the multi-copper protein family that have developed from small-sized prokaryotic azurins to eukaryotic plasma proteins.
This paper references
CotA of Bacillus subtilis is a copper-dependent laccase.
M. Hullo (2001)
Polyphenol oxidase in Azospirillum lipoferum isolated from rice rhizosphere: Evidence for laccase activity in non-motile strains of Azospirillum lipoferum
A. Givaudan (1993)
Identification and characterization of a gene cluster involved in manganese oxidation by spores of the marine Bacillus sp. strain SG-1.
L. V. van Waasbergen (1996)
Molecular cloning and functional characterization of a unique multipotent polyphenol oxidase from Marinomonas mediterranea.
A. Sánchez-Amat (2001)
Enzymatic Manganese(II) Oxidation by a Marine α-Proteobacterium
C. A. Francis (2001)
Phenolic derivatives related to lignin metabolism as substrates for Azospirillum laccase activity
D. Faure (1996)
Molecular cloning, chromosomal mapping, and sequence analysis of copper resistance genes from Xanthomonas campestris pv. juglandis: homology with small blue copper proteins and multicopper oxidase.
Y. A. Lee (1994)
Laccase activity tests and laccase inhibitors.
C. Johannes (2000)
Crystal structures of the Met148Leu and Ser86Asp mutants of rusticyanin from Thiobacillus ferrooxidans: insights into the structural relationship with the cupredoxins and the multi copper proteins.
L. Kanbi (2002)
Potential applications of oxidative enzymes and phenoloxidase-like compounds in wastewater and soil treatment: a review
N. Durán (2000)
Degradation and transformation of aquatic humic substances by laccase-producing fungi Cladosporium cladosporioides and Polyporus versicolor
H. Claus (1998)
Partial purification and characterization of manganese-oxidizing factors of Pseudomonas fluorescens GB-1.
M. Okazaki (1997)
Structure of the M148Q mutant of rusticyanin at 1.5 A: a model for the copper site of stellacyanin.
M. Hough (2001)
The complete genome of the hyperthermophilic bacterium Aquifex aeolicus
G. Deckert (1998)
Isolation of Azospirillum lipoferum 4T Tn5 Mutants Affected in Melanization and Laccase Activity.
D. Faure (1994)
Structural studies on copper-containing plant oxidases.
A. Messerschmidt (1992)
The evidence of a laccase-like enzyme activity in a Bacillus sphaericus strain
H. Claus (1997)
Fungal laccase: properties and activity on lignin
A. Leonowicz (2001)
Purification and preliminary crystallographic study of Trametes versicolor laccase in its native form.
T. Bertrand (2002)
Purification and characterization of laccase from white rot fungus Trametes sanguinea M85-2
Y. Nishizawa (1995)
Syringaldazine, an effective reagent for detecting laccase and peroxidase in fungi
J. Harkin (2005)
Characterization of extracellular Mn2+-oxidizing activity and isolation of an Mn2+-oxidizing protein from Leptothrix discophora SS-1.
L. Adams (1987)
Oxidation of phenolate siderophores by the multicopper oxidase encoded by the Escherichia coli yacK gene.
C. Kim (2001)
The structure and function of fungal laccases
C. Thurston (1994)
Purification and characterization of the first bacterial laccase in the rhizospheric bacterium Azospirillum lipoferum
Grigorios Diamantidis (2000)
Recent advances on the molecular genetics of ligninolytic fungi.
D. Cullen (1997)
Comparison of Fungal Laccases and Redox Mediators in Oxidation of a Nonphenolic Lignin Model Compound
K. Li (1999)
Laccase-Catalyzed Oxidation of Mn2+ in the Presence of Natural Mn3+ Chelators as a Novel Source of Extracellular H2O2 Production and Its Impact on Manganese Peroxidase
D. Schlosser (2002)
The blue oxidases, ascorbate oxidase, laccase and ceruloplasmin. Modelling and structural relationships.
A. Messerschmidt (1990)
A novel extracytoplasmic phenol oxidase of Streptomyces: its possible involvement in the onset of morphogenesis.
K. Endo (2002)
Laccase: new functions for an old enzyme.
A. M. Mayer (2002)
Laccase: properties, catalytic mechanism, and applicability
A. Yaropolov (1994)
Copper resistance in Pseudomonas syringae mediated by periplasmic and outer membrane proteins.
J. S. Cha (1991)
Aromatic ring cleavage of 4,6‐di(tert‐butyl)guaiacol, a phenolic lignin model compound, by laccase of Coriolus versicolor
S. Kawai (1988)
Stoichiometry and spectroscopic identity of copper centers in phenoxazinone synthase: a new addition to the blue copper oxidase family.
J. Freeman (1993)
Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum
S. Fitz-Gibbon (2002)
Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments.
H. Takami (2002)
Is heat the only factor inducing thermotaxis in Dictyostelium discoideum pseudoplasmodia
M. Kitami (1983)
Loss of cytochrome c oxidase activity and acquisition of resistance to quinone analogs in a laccase-positive variant of Azospirillum lipoferum.
G. Alexandre (1999)
Laccases are widespread in bacteria.
G. Alexandre (2000)
Laccase-like Activity of Nucleoside Oxidase in the Presence of Nucleosides
Yoshikazu Isono (1989)
Partial purification and characterization of mangeneseoxidizing factors of Pseudomonas fluorescens GB1
M Okazaki (1997)
A pluripotent polyphenol oxidase from the melanogenic marine Alteromonas sp shares catalytic capabilities of tyrosinases and laccases.
A. Sánchez-Amat (1997)
Comparative Study of Substrates and Inhibitors of Azospirillum lipoferum and Pyricularia oryzae Laccases.
D. Faure (1995)
Laccase and the Deposition of Lignin in Vascular Plants
J. F. Dean (1994)
Crystal structure and electron transfer kinetics of CueO, a multicopper oxidase required for copper homeostasis in Escherichia coli
S. Roberts (2002)
Die Laccasen des Ascomyceten Podospora anserina: Beiträge zur Kenntnis von Struktur und Funktion eines Systems multipler Enzyme
H. Molitoris (1976)
cumA Multicopper Oxidase Genes from Diverse Mn(II)-Oxidizing and Non-Mn(II)-OxidizingPseudomonas Strains
C. A. Francis (2001)
cumA, a Gene Encoding a Multicopper Oxidase, Is Involved in Mn2+ Oxidation in Pseudomonas putida GB-1
G. Brouwers (1999)
Oxidative coupling of aromatic compounds by enzymes from soil microorganisms
RD Sjoblad (1981)
Purification, crystallisation and X-ray diffraction study of fully functional laccases from two ligninolytic fungi.
Matteo Antorini (2002)
A fungal metabolite mediates degradation of non‐phenolic lignin structures and synthetic lignin by laccase
C. Eggert (1996)
Dimethoxyphenol oxidase activity of different microbial blue multicopper proteins.
F. Solano (2001)
Molecular and Biochemical Characterization of a Highly Stable Bacterial Laccase That Occurs as a Structural Component of theBacillus subtilis Endospore Coat*
L. Martins (2002)
This paper is referenced by
Vladimir Jiranek Angela Matthews , Antonio Grimaldi , Michelle Walker , of Enzymes for Use in Vinification Lactic Acid Bacteria as a Potential Source
Angela Matthews (2004)
Copper(I) ATPases: Transport Mechanism and Cellular Functions in Bacteria
J. M. Argüello (2013)
Chemo‐Enzymatic Oxidative Rearrangement of Tertiary Allylic Alcohols: Synthetic Application and Integration into a Cascade Process
E. Brenna (2018)
Current Trends in the Production of Ligninolytic Enzymes
S. Rodríguez-Couto (2019)
Laccase-catalyzed carbon–nitrogen bond formation: coupling and derivatization of unprotected l-phenylalanine with different para-hydroquinones
V. Hahn (2008)
Changes in the phyllosphere community of the resurrection fern, Polypodium polypodioides, associated with rainfall and wetting.
Evelyn F. Jackson (2006)
Development of strong enzymatic biocatalysts for dye decolorization
C. Britos (2016)
X‐ray structure of a two‐domain type laccase: A missing link in the evolution of multi‐copper proteins
H. Komori (2009)
Formation of protein-oligosaccharide conjugates by laccase and tyrosinase.
Emilia Selinheimo (2008)
Characterization of PIR1, a GATA family transcription factor involved in iron responses in the white-rot fungus Phanerochaete chrysosporium.
P. Canessa (2012)
Industrial and biotechnological applications of ligninolytic enzymes of the basidiomycota: A review
Márcia Jaqueline Mendonça Maciel (2010)
EFECTO DEL pH INICIAL DE DESARROLLO DE Pleurotus ostreatus EN FERMENTACIÓN SUMERGIDA SOBRE SU ACTIVIDAD DE LACASAS
Ciba-Ipn Tlaxcala (2009)
Investigating the lignocellulolytic gut microbiome of huhu grubs
Jayadev Payyakkal Viswam (2016)
A novel laccase with inhibitory activity towards HIV-I reverse transcriptase and antiproliferative effects on tumor cells from the fermentation broth of mushroom Pleurotus cornucopiae.
Xiangli Wu (2014)
Fungi from Extreme Environments: A Potential Source of Laccases Group of Extremozymes
O. Prakash (2019)
Bifunctional in vivo role of laccase exploited in multiple biotechnological applications
A. Sharma (2018)
Sprouting and Solid-State Bioprocessing by Rhizopus oligosporus Increase the In Vitro Antibacterial Activity of Aqueous Soybean Extracts Against Helicobacter pylori
P. McCue (2004)
Laccases from actinomycetes for lignocellulose degradation
T. P. Mamphogoro (2012)
Induction of laccase production and analysis of laccase isozymes in Trichophyton rubrum LKY-7
Eun Seon Shin (2010)
Microbial Extracellular Enzymes and the Degradation of Natural and Synthetic Polymers in Soil
R. Burns (2013)
Expression and Characterization of a Recombinant Laccase with Alkalistable and Thermostable Properties from Streptomyces griseorubens JSD-1
Haiwei Feng (2015)
Knockdown of a laccase in Populus deltoides confers altered cell wall chemistry and increased sugar release
A. Bryan (2016)
The multicopper oxidase CutO confers copper tolerance to Rhodobacter capsulatus.
J. Wiethaus (2006)
RECOMBINANT EXPRESSION AND CHARACTERIZATION OF TWO ISOFORMS OF ANOPHELES GAMBIAE LACCASE-2
M. Kanost (2009)
Biodecolorization of textile dye effluent by Pseudomonas putida SKG-1 (MTCC 10510) under the conditions optimized for monoazo dye orange II color removal in simulated minimal salt medium
S. Garg (2012)
Laccase - A Wonder Molecule : A Review of its Properties and Applications
Hiren V. Prajapati (2018)
Expanding the laccase-toolbox: a laccase from Corynebacterium glutamicum with phenol coupling and cuprous oxidase activity.
Esther Ricklefs (2014)
Lignin Biodegradation with Laccase-Mediator Systems
L. Christopher (2014)
Decolourization of synthetic dyes by laccase enzyme produced by Kluyveromyces dobzhanskii DW1 and Pichia manshurica DW2
S. M. Wakil (2019)
Chitosan Microbeads as Supporter for Pseudomonas putida with Surface Displayed Laccases for Decolorization of Synthetic Dyes
Zhiqiang Bai (2019)
Laccase-mediator systems and their applications: A review
O. Morozova (2007)
Gene cloning, identification, and characterization of the multicopper oxidase CumA from Pseudomonas sp. 593
Sheng Yang (2017)See more