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Functional MRI Of Tongue Motor Tasks In Patients With Tongue Cancer: Observations Before And After Partial Glossectomy

Samantha Haupage, K. Peck, R. Branski, M. Hsu, A. Holodny, D. Kraus
Published 2010 · Medicine

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IntroductionThe current study seeks to provide preliminary data regarding this central, adaptive response during tongue motor tasks utilizing functional magnetic resonance imaging (fMRI) before and after glossectomy.MethodsSix patients, with confirmed histological diagnoses of oral tongue cancer, underwent fMRI before and 6 months after partial glossectomy. These data were compared to nine healthy controls. All subjects performed three tongue motor tasks during fMRI: tongue tapping (TT), dry swallow (Dry), and wet swallow (Wet).ResultsFollowing surgery, increased activation was subjectively observed in the superior parietal lobule, supplementary motor area, and anterior cingulate. Region of interest (ROI) analysis of the precentral gyrus confirmed increased cortical activity following surgery. In addition, comparisons between pre-surgical scans and controls suggested the dry swallow task was sensitive to elicit tongue-related activation in the precentral gyrus (p ≤ 0.05).ConclusionsThe adaptive changes in the cortex following partial glossectomy reflect recruitment of the parietal, frontal, and cingulate cortex during tongue motor tasks. In addition, post-operative activation patterns more closely approximated control levels than the pre-operative scans. Furthermore, the dry swallow task appears most specific to elicit tongue-related cortical activity.
This paper references
10.1002/MRM.1910310307
Artifacts due to stimulus correlated motion in functional imaging of the brain
J. Hajnal (1994)
10.1006/CBMR.1996.0014
AFNI: software for analysis and visualization of functional magnetic resonance neuroimages.
R. Cox (1996)
10.1006/nimg.1999.0498
Stochastic Designs in Event-Related fMRI
Karl J. Friston (1999)
10.1002/ANA.410310502
Functional reorganization of the brain in recovery from striatocapsular infarction in man
C. Weiller (1992)
10.1152/JN.2001.85.2.938
Cerebral cortical representation of automatic and volitional swallowing in humans.
R. Martin (2001)
10.1002/(SICI)1097-0193(1997)5:5<329::AID-HBM1>3.0.CO;2-5
Selective averaging of rapidly presented individual trials using fMRI
A. Dale (1997)
10.1016/j.bandl.2004.08.004
Improved picture naming in chronic aphasia after TMS to part of right Broca’s area: An open-protocol study
M. Naeser (2005)
10.1097/00005537-199806000-00022
Surgical Variables Affecting Speech in Treated Patients With Oral and Oropharyngeal Cancer
B. Pauloski (1998)
10.1002/hbm.20743
Neural activation of swallowing and swallowing‐related tasks in healthy young adults: An attempt to separate the components of deglutition
G. Malandraki (2009)
10.1097/00005537-199909000-00011
Cortical Representation of Swallowing in Normal Adults: Functional Implications
K. Mosier (1999)
10.1007/s00455-003-0509-5
Cortical Regulation During the Early Stage of Initiation of Voluntary Swallowing in Humans
Y. Watanabe (2003)
10.1177/10454411010120010101
Neural control of tongue movement with respect to respiration and swallowing.
A. Sawczuk (2001)
10.1177/000348940511400905
Cortical Adaptation following Partial Glossectomy with Primary Closure: Implications for Reconstruction of the Oral Tongue
K. Mosier (2005)
10.1002/MRM.1910300204
Processing strategies for time‐course data sets in functional mri of the human brain
P. Bandettini (1993)
10.1016/S1388-2457(03)00237-2
Neurophysiology of swallowing
C. Ertekin (2003)
10.1007/s00455-009-9250-z
Age-Related Differences in Laterality of Cortical Activations in Swallowing
G. Malandraki (2009)
10.1002/hed.20013
Surgical variables affecting swallowing in patients treated for oral/oropharyngeal cancer
B. Pauloski (2004)
10.1016/S1047-9651(03)00124-4
Integrated technology for evaluation of brain function and neural plasticity.
P. Rossini (2004)
10.1007/s002210100813
Parallel cortical networks for volitional control of swallowing in humans
K. Mosier (2001)
10.1002/j.2048-7940.1991.tb01231.x
Rehabilitation of Swallowing and Communication Following Glossectomy
G. R. LaBlance (1991)



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