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Activation Of Cerebellum And Basal Ganglia On Volitional Swallowing Detected By Functional Magnetic Resonance Imaging

M. Suzuki, Y. Asada, J. Ito, K. Hayashi, H. Inoue, H. Kitano
Published 2003 · Medicine

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Although regions of the sensorimotor cortex, insula, and anterior cingulate gyrus are reported to be activated during swallowing, findings concerning contributions of the cerebellum and basal ganglia have been contradictory. We investigated cerebellar and basal ganglionic activation using functional magnetic resonance imaging (fMRI). In 11 subjects, single-shot gradient-echo echoplanar image volumes sensitive to BOLD contrast were acquired in block design fashion using an oblique orientation covering both cerebrum and cerebellum. Using statistical parametric mapping, regional activation upon swallowing was observed in the sensorimotor cortex, insula, cerebellum, putamen, globus pallidus, thalamus, anterior cingulate gyrus, supplementary motor area, superior temporal gyrus, and substancia nigra. The cerebellum was activated bilaterally, especially on the left; activation of the putamen and globus pallidus was also found bilaterally. Thus, volitional swallowing involves the cerebellum and basal ganglia as well as cortical structures. The method used was well tolerated by normal subjects and should also be applicable to patients with dysphagia.
This paper references
10.1152/JN.1999.81.4.1917
Identification of the cerebral loci processing human swallowing with H2(15)O PET activation.
S. Hamdy (1999)
Basal ganglia as a sensory gating devise for motor control.
R. Kaji (2001)
10.1111/j.1749-6632.1990.tb48897.x
Does the Cerebellum Provide a Common Computation for Diverse Tasks? A Timing Hypothesis a
S. Keele (1990)
10.1016/0168-0102(94)90038-8
The supplementary motor area in the cerebral cortex
J. Tanji (1994)
10.1006/nimg.1999.0484
Multisubject fMRI Studies and Conjunction Analyses
Karl J. Friston (1999)
10.1152/JN.2001.85.2.938
Cerebral cortical representation of automatic and volitional swallowing in humans.
R. Martin (2001)
10.1152/AJPGI.2001.280.3.G354
Cerebral cortical representation of reflexive and volitional swallowing in humans.
M. Kern (2001)
10.1016/S0166-2236(99)01439-3
Parallel neural networks for learning sequential procedures
O. Hikosaka (1999)
10.1002/MRM.1910400108
Magnetic field changes in the human brain due to swallowing or speaking
R. Birn (1998)
10.1006/nimg.2001.0746
Modeling Geometric Deformations in EPI Time Series
J. Andersson (2001)
10.1097/00001416-199301000-00012
The Cerebellum and the Adaptive Coordination of Movement. Thach WT, Goodkin HP, Keating JG. Ann Rev Neurosci 15:403-442, 1992.
V. Lovelace-Chandler (1993)
Talairach: Co-planar stereotaxic atlas of the human brain
J. Talairach (1988)
Cerebral structures in three - dimensional space
J Talairach
10.1152/ajpgi.1999.277.1.G219
Cortical activation during human volitional swallowing: an event-related fMRI study.
S. Hamdy (1999)
10.1007/s002210100813
Parallel cortical networks for volitional control of swallowing in humans
K. Mosier (2001)
10.1152/AJPGI.2001.280.4.G531
Swallow-related cerebral cortical activity maps are not specific to deglutition.
M. Kern (2001)
10.1097/00005537-199909000-00011
Cortical Representation of Swallowing in Normal Adults: Functional Implications
K. Mosier (1999)
10.1002/(SICI)1097-0193(1999)7:2<106::AID-HBM4>3.0.CO;2-O
Event‐related fMRI of tasks involving brief motion
R. Birn (1999)
10.1002/1531-8249(199909)46:3<281::AID-ANA2>3.0.CO;2-L
The functional neuroanatomy of voluntary swallowing
D. Zald (1999)
10.1146/ANNUREV.NE.15.030192.002155
The cerebellum and the adaptive coordination of movement.
W. Thach (1992)
10.1097/00005537-200107000-00010
Functional Magnetic Resonance Imaging of the Pediatric Swallow: Imaging the Cortex and the Brainstem
C. Hartnick (2001)



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10.1016/j.clinph.2020.06.018
Reproducibility and reaction time of swallowing as markers of dysphagia in parkinsonian syndromes
G. Cosentino (2020)
10.1044/2019_AJSLP-19-00088
Motor Learning, Neuroplasticity, and Strength and Skill Training: Moving From Compensation to Retraining in Behavioral Management of Dysphagia.
E. Zimmerman (2020)
PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO GRANDE DO SUL INSTITUTO DE GERIATRIA E GERONTOLOGIA PROGRAMA DE PÓS-GRADUAÇÃO EM GERONTOLOGIA BIOMÉDICA
M. D. Oliveira (2014)
Funktionelle Bildgebung der cerebralen Repräsentation des Schluckens
N. Hosten (2015)
10.14802/jmd.19048
Oro-Pharyngeal Dysphagia in Parkinson’s Disease and Related Movement Disorders
Miseon Kwon (2019)
10.1044/PERSP2.SIG13.4
Swallowing Exercises in Patients Post-Stroke: What Is the Current Evidence?
Balaji Rangarathnam (2017)
Skill versus Strength in Swallowing Training: Neurophysiological, Biomechanical, and Structural Assessments
Oshrat Sella (2012)
10.1093/hmg/ddn117
Analysis of cerebellar function in Ube3a-deficient mice reveals novel genotype-specific behaviors.
D. Heck (2008)
10.1016/B978-0-444-52901-5.00021-6
Chapter 21 - Dysphagia
G. Malandraki (2013)
10.1007/s00415-006-0122-2
Swallowing in degenerative ataxias
L. Ramio-Torrentia (2006)
10.1007/s00455-017-9794-2
Swallowing Preparation and Execution: Insights from a Delayed-Response Functional Magnetic Resonance Imaging (fMRI) Study
J. A. Toogood (2017)
10.1007/s15006-019-0961-2
Schluckstörungen bei Senioren sind keine Bagatelle
Donata Gellrich (2019)
10.1113/jphysiol.2007.144592
Unilateral suppression of pharyngeal motor cortex to repetitive transcranial magnetic stimulation reveals functional asymmetry in the hemispheric projections to human swallowing
S. Mistry (2007)
10.1016/S1639-870X(07)70186-1
Fisiologia della deglutizione normale
L. Crevier-Buchman (2007)
10.1101/577148
Swallowing and chewing difficulties are associated with presynaptic dopaminergic dysfunction and greater non-motor symptom burden in early drug-naïve Parkinson’s patients
S. Polychronis (2019)
10.1002/hbm.23767
Decoding fMRI events in sensorimotor motor network using sparse paradigm free mapping and activation likelihood estimates
Francisca M Tan (2017)
10.1136/gut.2009.208975r
OC-070 Assessment of rectal compliance and sensory function following temporary sacral nerve stimulation
M. Abdel-Halim (2010)
10.1007/s00455-013-9450-4
Differences in Dysphagia Between Spinocerebellar Ataxia Type 3 and Type 6
C. Isono (2013)
10.1101/784769
Loss of cerebellar function selectively affects intrinsic rhythmicity of eupneic breathing
Y. Liu (2019)
10.1016/j.exger.2018.11.007
Brain signatures associated with swallowing efficiency in older people
Chia-shu Lin (2019)
10.1007/s00415-011-6129-3
Dysphagia in patients with acute striatocapsular hemorrhage
S. Suntrup (2011)
10.1159/000487800
Characteristics of Early Oropharyngeal Dysphagia in Patients with Multiple System Atrophy
H. Lee (2018)
Multisensory integration of olfaction
Robert A. Österbauer (2007)
10.1007/s00455-015-9627-0
Hypersialorrhea in Wilson’s Disease
Jean-Marc Trocello (2015)
Tele-rehabilitacioåln en la disfagia orofariålngea: un nuevo paradigma para tratar y empoderar a nuestros pacientes
H. B. Ambrós (2015)
10.1016/B978-0-323-18701-5.00003-8
Chapter 3 – Adult Neurologic Disorders
M. Crary (2016)
10.1044/2020_AJSLP-19-00073
Advances in the Use of Neuromodulation for Neurogenic Dysphagia: Mechanisms and Therapeutic Application of Pharyngeal Electrical Stimulation, Transcranial Magnetic Stimulation, and Transcranial Direct Current Stimulation.
A. Sasegbon (2020)
10.1161/STROKEAHA.108.518969
Neuroanatomical Basis of Swallowing disorders after Stroke: A Pilot Study
M. González-Fernández (2008)
10.1113/JP270817
High‐frequency focal repetitive cerebellar stimulation induces prolonged increases in human pharyngeal motor cortex excitability
D. Vasant (2015)
10.1111/nmo.13609
Rapid improvement in brain and swallowing behavior induced by cerebellar repetitive transcranial magnetic stimulation in poststroke dysphagia: A single patient case‐controlled study
D. Vasant (2019)
10.11334/JIBI.62.5_151
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朝則 喜友名 (2016)
10.1101/726711
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Jason A. Avery (2019)
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