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The Relationship Between Lesion Localization And Dysphagia In Acute Stroke

S. Daniels, Shweta Pathak, Shalini V. Mukhi, Carol B. Stach, R. Morgan, Jane A. Anderson
Published 2017 · Medicine

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Factors that can facilitate early identification of individuals at risk of dysphagia such as stroke location are potentially of great benefit. The aim of this study was to examine the role of hemisphere and lesion location in assessing dysphagia pattern and airway invasion as identified through the use of validated, standardized interpretation measures for the videofluoroscopic swallowing study. Consecutive patients (N = 80) presenting with stroke symptoms who had a first-time acute ischemic stroke confirmed on diffusion-weighted magnetic resonance imaging (DW-MRI) scan participated. Three swallowing outcome variables were assessed using regression models: modified barium swallow impairment profile (MBSImP) oral impairment (OI) and pharyngeal impairment (PI) scores and penetration aspiration scale (PAS) score. Subjects were primarily male and demonstrated mild stroke and mild to moderate dysphagia. There was a significantly higher likelihood of abnormal PAS scores for infratentorial lesions compared to right hemisphere location (Odds ratio: 3.1, SE: 1.8, p = 0.046) and for Whites compared to African Americans (Odds ratio: 5.5, SE: 2.6, p = <0.001). However, OI scores were higher (worse) in African Americans compared to Whites (Beta = −1.2; SE: 0.56; p = 0.037). PI scores had no significant association with race or lesion location. Using DW-MRI to identify infratentorial stroke can help identify individuals at risk of airway invasion; however, imaging information concerning supratentorial infarct hemisphere and location may not be useful to predict which individuals with mild stroke are at risk for dysphagia and aspiration when admitted with acute stroke symptoms. Future studies should explore the role of race in the development of stroke-related dysphagia.
This paper references
10.1161/STROKEAHA.108.518969
Supratentorial Regions of Acute Ischemia Associated With Clinically Important Swallowing Disorders: A Pilot Study
M. González-Fernández (2008)
10.1016/S1052-3057(96)80018-8
Lesion site in unilateral stroke patients with dysphagia.
B. Jacobson (1996)
10.1161/STROKEAHA.113.001690
Lesion Location Predicts Transient and Extended Risk of Aspiration After Supratentorial Ischemic Stroke
M. Galovic (2013)
10.1159/000324940
MRI-Based Neuroanatomical Predictors of Dysphagia after Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
H. Flowers (2011)
10.1016/0003-9993(93)90082-L
Swallowing after unilateral stroke of the cerebral cortex.
J. Robbins (1993)
10.1007/BF02493452
Aspiration after stroke: Lesion analysis by brain MRI
M. Alberts (2006)
10.1007/978-1-4614-3794-9_5
Cerebral Cortical Control of Deglutition
D. Vasant (2013)
10.1016/j.apmr.2016.03.025
Rapid Aspiration Screening for Suspected Stroke: Part 1: Development and Validation.
S. Daniels (2016)
10.3109/14417040008996802
The Neuroscientific Principles of Swallowing and Dysphagia
A. Miller (2000)
10.1111/ene.12670
The impact of lesion location on dysphagia incidence, pattern and complications in acute stroke. Part 1: dysphagia incidence, severity and aspiration
S. Suntrup (2015)
10.1016/j.apmr.2008.02.016
Racial disparities in the development of dysphagia after stroke: analysis of the California (MIRCal) and New York (SPARCS) inpatient databases.
M. González-Fernández (2008)
10.1111/jon19999291
Lesion Localization in Acute Stroke
S. Daniels (1999)
10.1161/01.STR.24.12.1823
A Model for Management of Patients With Stroke During the Acute Phase: Outcome and Economic Implications
I. Odderson (1993)
10.1007/s004559910006
Screening for Oropharyngeal Dysphagia in Stroke: Insufficient Evidence for Guidelines
R. Martino (2000)
10.1016/j.jstrokecerebrovasdis.2009.01.009
Oropharyngeal dysphagia after stroke: incidence, diagnosis, and clinical predictors in patients admitted to a neurorehabilitation unit.
P. Falsetti (2009)
10.1152/PHYSREV.2001.81.2.929
Brain stem control of swallowing: neuronal network and cellular mechanisms.
A. Jean (2001)
10.1161/01.STR.0000190056.76543.eb
Dysphagia After Stroke: Incidence, Diagnosis, and Pulmonary Complications
R. Martino (2005)
10.1007/s00455-008-9185-9
MBS Measurement Tool for Swallow Impairment—MBSImp: Establishing a Standard
Bonnie Martin-Harris (2008)
10.1007/BF00236530
Identification of the medullary swallowing regions in the rat
J. Kessler (2004)
10.1161/STROKEAHA.109.566133
Relevance of Subcortical Stroke in Dysphagia
M. Cola (2010)
10.1097/EDE.0000000000000186
On the Causal Interpretation of Race
T. VanderWeele (2014)
Brain control of swallowing: neuronal network and cellular mechanisms
A. Jean (2001)
10.1007/BF00417897
A penetration-aspiration scale
J. Rosenbek (2004)
10.1161/01.STR.0000177529.86868.8d
Formal Dysphagia Screening Protocols Prevent Pneumonia
J. Hinchey (2005)
10.1044/SASD8.2.18
Book Reviews: The Neuroscientific Principles of Swallowing and Dysphagia
K. Brewster (1999)
10.12786/BN.2014.7.1.54
Association between Location of Brain Lesion and Clinical Factors and Findings of Videofluoroscopic Swallowing Study in Subacute Stroke Patients
Woo Hyun Jeon (2014)
Multicollinearity in Regression Analyses Conducted in Epidemiologic
M. Lee (2016)
10.1016/j.apmr.2010.12.005
Racial disparities in the development of dysphagia after stroke: further evidence from the Medicare database.
S. Bussell (2011)



This paper is referenced by
10.1016/j.nicl.2019.101685
Mapping acute lesion locations to physiological swallow impairments after stroke
J. Wilmskoetter (2019)
Kobe University Repository : Kernel タイトル Tit le Inappropriate Timing of Swallow in the Respiratory Cycle Causes Breathing-Swallowing
Naomi Yagi (2019)
10.1055/s-0039-1688815
Clinical Decision Making in Patients with Stroke-Related Dysphagia.
Cecilia Felix (2019)
10.1080/10749357.2019.1623519
Relationship between pharyngeal response time and lateralized brain lesion in stroke
Thaís Coelho Alves (2019)
10.5535/arm.2019.43.2.149
Comparison of Dysphagia Between Infratentorial and Supratentorial Stroke Patients
Y. K. Kim (2019)
10.1111/nmo.13953
Role of rs6265 BDNF polymorphisms and post‐stroke dysphagia recovery—A prospective cohort study
Hyun Mi Oh (2020)
10.1097/MRR.0000000000000385
Post-stroke dysphagia rehabilitation in the old and oldest old: outcome and relevance for discharge home
A. Castagna (2019)
10.5535/arm.2019.43.1.11
Effects of Neuromuscular Electrical Stimulation for Masseter Muscle on Oral Dysfunction After Stroke
K. W. Lee (2019)
10.1007/s00455-019-10064-3
Use of the Penetration-Aspiration Scale in Dysphagia Research: A Systematic Review
James C Borders (2019)
10.1016/j.physbeh.2018.05.010
Differences in swallow physiology in patients with left and right hemispheric strokes
J. Wilmskoetter (2018)
10.1007/s11910-020-01081-z
Post-stroke Dysphagia: Recent Insights and Unanswered Questions
C. Jones (2020)
10.1007/s00455-020-10204-0
Ischemic Lesion Location Based on the ASPECT Score for Risk Assessment of Neurogenic Dysphagia
Sriramya Lapa (2020)
10.5535/arm.2019.43.2.142
Association Between Duration of Dysphagia Recovery and Lesion Location on Magnetic Resonance Imaging in Patients With Middle Cerebral Artery Infarction
J. Kim (2019)
10.1016/j.jstrokecerebrovasdis.2019.04.025
Predictive Factors of Swallowing Disorders and Bronchopneumonia in Acute Ischemic Stroke.
Avinash Beharry (2019)
10.1044/2020_AJSLP-20-00027
Factors Influencing Initiation of Pharyngeal Swallow in Healthy Adults.
Ankita M. Bhutada (2020)
10.1044/2019_AJSLP-19-00068
Cortical and Subcortical Control of Swallowing-Can We Use Information From Lesion Locations to Improve Diagnosis and Treatment for Patients With Stroke?
J. Wilmskoetter (2020)
10.1007/s00415-020-10244-4
Association between stroke lesions and videofluoroscopic findings in acute stroke patients
M. Nakamori (2020)
10.3389/fphys.2017.00676
Inappropriate Timing of Swallow in the Respiratory Cycle Causes Breathing–Swallowing Discoordination
Naomi Yagi (2017)
10.3389/fneur.2019.00817
Early Predictors for Infectious Complications in Patients With Spontaneous Intracerebral Hemorrhage and Their Impact on Outcome
A. Lindner (2019)
10.5762/KAIS.2019.20.7.36
Characteristics of the Oropharyngeal Swallowing Impairment in Stroke Patient using the Modified Barium Swallowing Impairment Profile
Ikjae Im (2019)
10.1007/s40141-020-00290-4
Avoiding the Downward Spiral After Stroke: Early Identification and Treatment of Dysphagia
Rachel W. Mulheren (2020)
10.1007/s00455-018-9963-y
The Relationship Between Leukoaraiosis Involving Contralateral Corticobulbar Tract and Dysphagia in Patients with Acute Unilateral Corona Radiata Infarction with Corticobulbar Tract Involvement
Eun Jae Ko (2018)
10.1016/j.apmr.2019.12.013
Inconsistent Classification of Mild Stroke and Implications of Health Services Delivery.
Pamela S Roberts (2020)
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