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News On The Journal Neurological Sciences In 2017

I. Donato, A. Federico
Published 2017 · Medicine

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As usually, we report in this survey the main advances in neurology and neurosciences, as reported in the articles published in Neurological Sciences in the 2017 volume and related to all the main topics of neurology. Cerebrovascular diseases remain among the dominant topics for neurological research and practice. A growing interest is addressed to pathophysiology of stroke [1], and especially toward genetic causes [2–4]. Early rehabilitation is linked to a better recovery and more positive outcomes [5, 6]. Infections, aneurysms, dissections, venous thrombosis, and autoimmune diseases are rarer cause of stroke which may be underconsidered in the final diagnosis [7–11]. It has been established that standardization of stroke assessment and organization of stroke networks could be able to reduce mortality and dependency in stroke patients [12]. Intravenous thrombolysis remains the standard treatment for acute ischemic stroke within 4.5 h of symptom onset. Extra-ischemic brain hemorrhages after thrombolysis for ischemic stroke occur in less than 3% of treated patients, but they worsen prognosis [13] and the administration of thrombolytic therapy in elderly patients with dementia and acute ischemic stroke is still controversial [14]. Multiple sclerosis (MS) is another very common topic. Since it usually occurs in young adults with a female prevalence and obvious difficulty management during pregnancy and puerperium, the collaboration between neurologists, gynecologists, and psychologists for an interdisciplinary approach has been reported [15]. Conventional magnetic resonance imaging (MRI) remains a fundamental tool to diagnose and monitor MS and advancedMRI techniques are improving the understanding of the mechanisms underlying tissue injury, repair, and functional adaptation in MS [16]. Pharmacological development for MS is growing up in the last years. Rescue therapy with alemtuzumab in multiple sclerosis post-natalizumab puerperium reactivation has shown high efficacy [17]. Safety and tolerability of fingolimod has been better understood [18, 19]. Therapeutic potential of curcumin is a matter of debate [20]. Tetrahydrocannabinolcannabidiol (THC/CBD) oromucosal spray has shown to be effective in improving overactive bladder symptoms in MS patients demonstrating a favorable impact on detrusor overactivity [21], and treatment with botulinum toxin type A (BoNTA) for MS-related spasticity has beneficial effects but also high level of discontinuation [22]. Myeloablative autologous hematopoietic stem cell transplant (AHSCT) has proven to be safe and efficacious to control the aggressive forms of MS with better outcome in RR-MS [23]. Alzheimer’s disease (AD) is the main cause of dementia, but rarer alternative diagnosis such as Creutzfeldt-Jakob disease and Whipple disease has to be considered [24, 25]. Also, dementia with Lewy body (LBD) is often misdiagnosed as AD [26, 27]. Association of arterial stiffness with cognition impairment in patients with Lewy body disorder has been evaluated and compared with AD findings [28]. Benzodiazepines (BZD) and cognitive impairment represent an interesting aspect of research, since patients with highdose BZD intake show profound changes in cognitive function [29]. Several articles reported neuropsychological assessments to distinguish AD from normal aging and from other dementias (vascular dementia, frontotemporal dementia, LBD) [30–35]. Recently, eye-tracking has been proposed as an integrative tool for cognitive assessment [36]. Cognitive training, active music therapy, and neuroeducation are emerging issues in mild-moderate AD [37, 38]. Parkinson’s disease (PD) is the most important field of research into movement disorders. The research of diagnostic and prognostic biomarkers is a field of high interest in PD [39–46]. Non-motor symptoms are now better recognized and treated [47–49]. Rasagiline has proved to be effective for dysexecutive syndrome [50]. Weight gain after subthalamic nucleus deep brain stimulation is a common side effect, * Antonio Federico
This paper references
Non-invasive vagus nerve stimulation (nVNS) as symptomatic treatment of migraine in young patients: a preliminary safety study
L. Grazzi (2017)
The role of anti-CGRP antibodies in the pathophysiology of primary headaches
P. Barbanti (2017)
A novel SPAST frameshift mutation in a Chinese family with hereditary spastic paraplegia
Wang Yu-liang (2016)
Adaptation and psychometric properties of the Italian version of the Non-Motor Symptoms Questionnaire for Parkinson’s disease
Ilaria Cova (2017)
Mobile phone use and risk of brain tumours: a systematic review of association between study quality, source of funding, and research outcomes
M. Prasad (2017)
Accompanying migrainous features in pediatric migraine patients with restless legs syndrome
M. S. Sevindik (2017)
Chronic demyelinating neuropathy with anti-myelin-associated glycoprotein antibody without any detectable M-protein
Yuki Sakamoto (2017)
Italian normative data and validation of two neuropsychological tests of face recognition: Benton Facial Recognition Test and Cambridge Face Memory Test
A. Albonico (2017)
Spontaneous brain activity in the sensorimotor cortex in amyotrophic lateral sclerosis can be negatively regulated by corticospinal fiber integrity
W. Sako (2017)
Long-term efficacy and side effects of low-dose tacrolimus for the treatment of Myasthenia Gravis
Xiaoyong Tao (2016)
Association of arterial stiffness with cognition in patients with Lewy body disorder
D. W. Ryu (2017)
Quarterly repeat cycles of onabotulinumtoxinA in chronic migraine patients: the benefits of the prolonged treatment on the continuous responders and quality-of-life conversion rate in a real-life setting
A. Santoro (2017)
Safety and tolerability of fingolimod in patients with relapsing-remitting multiple sclerosis: results of an open-label clinical trial in Italy
A. Laroni (2016)
Onabotulinumtoxin A for chronic migraine with medication overuse: clinical results of a long-term treatment
L. Grazzi (2017)
Analysis of hematological parameters in patients treated with ketogenic diet due to drug-resistant epilepsy
Engin Kose (2017)
Music intervention on cognitive dysfunction in healthy older adults: a systematic review and meta-analysis
B. Xu (2017)
Neurosyphilis combined with acute anterior thalamic infarction
Jin San Lee (2017)
Rescue therapy with alemtuzumab in multiple sclerosis post-natalizumab puerperium reactivation
Jessica Frau (2017)
The Tower of London (ToL) in Italy: standardization of the ToL test in an Italian population
Maddalena Boccia (2017)
An eye-tracking controlled neuropsychological battery for cognitive assessment in neurological diseases
B. Poletti (2016)
Combined visual and semi-quantitative assessment of 123I-FP-CIT SPECT for the diagnosis of dopaminergic neurodegenerative diseases
J. Ueda (2017)
Cognitive training in Alzheimer’s disease: a controlled randomized study
A. Giovagnoli (2017)
Phenotypic variability of TTR Val122Ile mutation: a Caucasian patient with axonal neuropathy and normal heart
C. Stancanelli (2016)
Epidemiological information of dementia with Lewy bodies
T. Kawada (2017)
Neuropsychological heterogeneity in patients with primary familial brain calcification due to a novel mutation in SLC20A2
C. Chiriaco (2017)
Calcitonin gene-related peptide antagonism and cluster headache: an emerging new treatment
Håkan Ashina (2017)
Do bilateral and unilateral greater occipital nerve block effectiveness differ in chronic migraine patients?
H. A. Ünal-Artık (2017)
Treatment with telmisartan, a long-acting angiotensin II receptor blocker, prevents migraine attacks in Japanese non-responders to lomerizine
Ken Ikeda (2017)
Phenotypic spectrum of POLG1 mutations
J. Finsterer (2017)
Association of cytochrome P4502E1 and NAD(P)H:quinone oxidoreductase 1 genetic polymorphisms with susceptibility to large artery atherosclerotic ischemic stroke: a case–control study in the Turkish population
Aysun Türkanoǧlu Özçelik (2017)
Sporadic Creutzfeldt-Jakob disease presenting with isolated progressive non-fluent aphasia in a young woman
A. Terrin (2017)
TLR4 polymorphisms affect stroke risk and inflammatory response in Chinese ischemic stroke patients
Lian Sheng Gu (2017)
Neurobiology of chronicization
G. C. Manzoni (2017)
Rasagiline for dysexecutive symptoms during wearing-off in Parkinson’s disease: a pilot study
Domiziana Rinaldi (2017)
SYNE1 related cerebellar ataxia presents with variable phenotypes in a consanguineous family from Turkey
E. Yucesan (2017)
SNCA 3′UTR genetic variants in patients with Parkinson’s disease and REM sleep behavior disorder
M. Toffoli (2017)
Intranasal sumatriptan for acute migraine attacks: a systematic review and meta-analysis
A. Menshawy (2017)
Essential trace elements in amyotrophic lateral sclerosis (ALS): Results in a population of a risk area of Italy
G. Forte (2017)
Flow-metabolism uncoupling in the cervical spinal cord of ALS patients
T. Yamashita (2017)
The Italian dementia with Lewy bodies study group (DLB-SINdem): toward a standardization of clinical procedures and multicenter cohort studies design
L. Bonanni (2016)
Treating migraine with contra
G Allais (2017)
MRI measurements of brainstem structures in patients with vascular parkinsonism, progressive supranuclear palsy, and Parkinson’s disease
B. C. Kim (2017)
Minor salivary gland biopsy for the diagnosis of familial amyloid polyneuropathy
Fernanda de Paula Eduardo (2016)
Lamivudine and fingolimod co-administration in two patients with multiple sclerosis and occult hepatitis B virus infection
Francesco Saccà (2016)
Health-related quality of life and ways of coping with stress in patients with migraine
M. Vladetić (2016)
Downbeat nystagmus as an initial clinical sign in spinocerebellar ataxia type 6
Tatsuya Ueno (2017)
A wearable proprioceptive stabilizer for rehabilitation of limb and gait ataxia in hereditary cerebellar ataxias: a pilot open-labeled study
L. Leonardi (2016)
Evaluation of inner retinal layers with optic coherence tomography in vigabatrin-exposed patients
Betül Tuğcu (2017)
Identification of a novel SPG4 tandem base substitution in a Chinese hereditary spastic paraplegia family
Guohua Zhao (2016)
Role of CACNA1C gene polymorphisms and protein expressions in the pathogenesis of schizophrenia: a case-control study in a Chinese population
Sheng-yu Zhang (2017)
Risk factors for unprovoked epileptic seizures in multiple sclerosis: a systematic review and meta-analysis
S. Gasparini (2016)
Camptocormia as an onset symptom of myasthenia gravis
Toko Sato (2016)
High frequencies of circulating Tfh-Th17 cells in myasthenia gravis patients
Yongxiang Yang (2017)
Epidemiology and cerebrovascular events related to cervical and intracranial arteries dissection: the experience of the city of Pisa
N. Giannini (2017)
Hub-and-spoke stroke network in the Veneto region: a retrospective study investigating the effectiveness of the stroke pathway and trends over time
L Nardetto (2017)
Association between brain structural anomalies, electroencephalogram and history of seizures in Mucopolysaccharidosis type II (Hunter syndrome)
R. E. Jiménez-Arredondo (2016)
Novel POLG mutations and variable clinical phenotypes in 13 Italian patients
P. Da Pozzo (2016)
Cognitive and behavioral disorders in Parkinson’s disease: an update. I: cognitive impairments
C. Papagno (2017)
Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy
E. Baldin (2016)
Weight gain after subthalamic nucleus deep brain stimulation in Parkinson’s disease is influenced by dyskinesias’ reduction and electrodes’ position
Roberta Balestrino (2017)
Multifocal cognitive dysfunction in high-dose benzodiazepine users: a cross-sectional study
Angela Federico (2016)
The effect of different ankle and knee supports on balance in early ambulation of post-stroke hemiplegic patients
Burcu Talu (2017)
Impact of serum uric acid, albumin and their interaction on Parkinson’s disease
Lijun Wang (2016)
Vitamin D supplementation: a useful strategy for restless legs syndrome exacerbation in a patient with Turner syndrome
L. Buratti (2017)
High-dose Ig VENA is well tolerated and efficacious in patients with multifocal motor neuropathy
Eduardo Nobile-Orazio (2017)
Thrombolysis in dementia patients with acute stroke: is it justified?
M. Paciaroni (2016)
Diagnostics of anti-MAG antibody polyneuropathy
D. Franciotta (2017)
Assessment of free and cued recall in Alzheimer’s disease and vascular and frontotemporal dementia with 24-item Grober and Buschke test
M. Cerciello (2016)
Plasma miR-122 as a potential diagnostic and prognostic indicator in human glioma
Ying Tang (2017)
Intravenous mannitol in status migrainosus treatment: a clinical case series
R. Simone (2017)
The Parkinson’s Disease-Cognitive Rating Scale (PD-CRS): normative values from 268 healthy Italian individuals
Gabriella Santangelo (2017)
Serum uric acid levels and freezing of gait in Parkinson’s disease
R. Ou (2017)
Cerebrospinal fluid levels of neurofilament light chain in multiple system atrophy relative to Parkinson’s disease: a meta-analysis
X. Hu (2016)
Early experience with compassionate use of 2 hydroxypropyl-beta-cyclodextrin for Niemann–Pick type C disease: review of initial published cases
J. E. Megías-Vericat (2017)
The SG13S114 polymorphism of the ALOX5AP gene is associated with ischemic stroke in Europeans: a meta-analysis of 8062 subjects
Zhongjun Chen (2016)
Role of CACNA 1 C gene polymorphisms and protein expressions in the pathogenesis of schizophrenia : a case - control study in a Chinese population
SY Zhang
Determinants of botulinum toxin discontinuation in multiple sclerosis: a retrospective study
P. Latino (2017)
Migraine with aura and white matter lesions: an MRI study
C. Uggetti (2017)
Management of pregnancy-related issues in multiple sclerosis patients: the need for an interdisciplinary approach
M. Amato (2017)
The PACE study: lifetime and past-year prevalence of headache in Parma’s adult general population
A. Taga (2017)
Neuropsychological assessment in migraine patients: a descriptive review on cognitive implications
M. Foti (2017)
Dissecating aneurysm of extracranial internal carotid artery presenting with Tapia syndrome in patient with essential thrombocythemia
Alessandro Introna (2017)
Atypical Leber’s hereditary optic neuropathy in a 10-year-old male: a case report
Y. J. Yoo (2017)
Cerebellar vermis: a vulnerable location of remote brain haemorrhages after thrombolysis for ischaemic stroke
Herbert Tejada-Meza (2016)
Serum methylmalonic acid correlates with neuropathic pain in idiopathic Parkinson’s disease
J. Park (2017)
Early rehabilitation: benefits in patients with severe acquired brain injury
R. Formisano (2016)
Behavioral therapy: emotion and pain, a common anatomical background
Lauren A.-M. Dahlke (2017)
Decreased serum proNGF concentration in patients with Parkinson’s disease
Xiao-Min Xu (2017)
Usefulness of nutraceuticals in migraine prophylaxis
F. D’onofrio (2017)
Perilesional edema in brain metastasis from non-small cell lung cancer (NSCLC) as predictor of response to radiosurgery (SRS)
P. Tini (2017)
Ketogenic diet in migraine: rationale, findings and perspectives
P. Barbanti (2017)
Treating migraine with contraceptives
Gianni Allais (2017)
Raven coloured progressive matrices in migraine without aura patients
Giovanna Viticchi (2017)
The use of nutraceutics in children‘s and adolescent’s headache
Roberto Sangermani (2017)
Capgras syndrome in Parkinson’s disease: two new cases and literature review
Antonino Cannas (2016)
A case of recurrent stroke due to late onset antiphospholipid syndrome
Marianna Riolo (2017)
The expression of miRNA-221 and miRNA-222 in gliomas patients and their prognosis
Liang Xue (2016)
Migraine with aura white matter lesions: preliminary data on clinical aspects
Alberto Galli (2017)
2017a) The SG13S114 polymorphism of the ALOX5AP gene is associated with ischemic stroke in Europeans: a meta-analysis
Z Chen (2017)
Contribution of auditory P300 test to the diagnosis of mild cognitive impairment in Parkinson’s disease
Fikriye Yilmaz (2017)
Phenytoin: neuroprotection or neurotoxicity?
J. K. Keppel Hesselink (2017)
Terminal latency abnormality in amyotrophic lateral sclerosis without split hand syndrome
Donghwi Park (2017)
The correlation of lymphocyte subsets, natural killer cell, and Parkinson’s disease: a meta-analysis
S. Jiang (2017)
Action mechanisms of Onabotulinum toxin-A: hints for selection of eligible patients
Carlo Lovati (2017)
Therapeutic potential of curcumin for multiple sclerosis
Munibah Qureshi (2017)
Edinburgh Cognitive and Behavioural ALS Screen (ECAS)-Italian version: regression based norms and equivalent scores
M. Siciliano (2017)
Wilson’s disease presenting as central pontine myelinolysis
Mahdi Safdarian (2017)
Prevalence of rapid eye movement sleep behavior disorder (RBD) in Parkinson’s disease: a meta and meta-regression analysis
X. Zhang (2016)
Transcutaneous supraorbital neurostimulation for the prevention of chronic migraine: a prospective, open-label preliminary trial
P. Fiore (2017)
Headache and arterial hypertension
C. Finocchi (2017)
Headache in children and dynamic thiol/disulfide balance evaluation with a new method
Aysegül Nese Citak Kurt (2017)
Serum glutathione peroxidase, xanthine oxidase, and superoxide dismutase activities and malondialdehyde levels in patients with Parkinson’s disease
B. Gökçe Çokal (2016)
Cerebral venous thrombosis: continental disparities
Laith Maali (2017)
Amyotrophic lateral sclerosis and myasthenia gravis: association or chance occurrence?
S. Pasqua (2016)
Vitamin D levels in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
Maria Alessandra Carluccio (2017)
Repeated sessions of transcranial direct current stimulation evaluation on fatigue and daytime sleepiness in Parkinson’s disease
B. Forogh (2016)
Cognitive and behavioral disorders in Parkinson’s disease: an update. II: behavioral disorders
L. Trojano (2017)
Autologous hematopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: comparison with secondary progressive multiple sclerosis
B. Casanova (2017)
The Italian Neuroimaging Network Initiative (INNI): enabling the use of advanced MRI techniques in patients with MS
Massimo Filippi (2017)
THC/CBD oromucosal spray in patients with multiple sclerosis overactive bladder: a pilot prospective study
G. Maniscalco (2017)
Thymectomy is a beneficial therapy for patients with non-thymomatous ocular myasthenia gravis: a systematic review and meta-analysis
Kai Zhu (2017)
Pathogenic mechanisms following ischemic stroke
S. E. Khoshnam (2017)
The Italian version of cognitive function instrument (CFI): reliability and validity in a cohort of healthy elderly
E. Chipi (2017)
Autism, epilepsy, and synaptopathies: a not rare association
R. Keller (2017)
Diagnostics of dysimmune peripheral neuropathies
D. Franciotta (2017)
SAND: a Screening for Aphasia in NeuroDegeneration. Development and normative data
E. Catricalà (2017)
Mindfulness and pharmacological prophylaxis have comparable effect on biomarkers of inflammation and clinical indexes in chronic migraine with medication overuse: results at 12 months after withdrawal
L. Grazzi (2017)
Pediatric migraine with aura in an Italian case series
A. Taga (2017)
A case of rapidly progressive dementia: Whipple disease of CNS
Maria Elena Pessa (2017)
VRT (verbal reasoning test): a new test for assessment of verbal reasoning. Test realization and Italian normative data from a multicentric study
Benedetta Basagni (2017)
Different phenotypes in identical twins with cerebrotendinous xanthomatosis: case series
D. Zádori (2016)
A case of Wilson’s disease presenting with paroxysmal dystonia
Hyun Jae Kim (2017)
Methylprednisolone plus diazepam i.v. as bridge therapy for medication overuse headache
Matteo Paolucci (2017)
Hormonal effect on the relationship between migraine and female sexual dysfunction
V. B. Dogan (2017)
Tremor analysis separates Parkinson’s disease and dopamine receptor blockers induced parkinsonism
Aasef G. Shaikh (2017)
Multifocal cognitive dysfunction in high Neurol Sci (2018) 39:15–21 17 dose benzodiazepine users: a cross-sectional study
A Federico (2017)
review of initial published cases
JE Megías-Vericat (2018)
Serial magnetic resonance study in super refractory status epilepticus: progressive involvement of striatum and pallidus is a possible predictive marker of negative outcome
Alessandra Ferrari (2017)
Compound heterozygosity in the GALC gene in a late onset Iranian patient with spastic paraparesis, peripheral neuropathy and leukoencephalopathy
Liana Africa (2017)
Guillain–Barré syndrome variant with facial diplegia and paresthesias after reactivation of varicella zoster virus
Xiaodong Chen (2017)
3-Hz postural tremor in multiple system atrophy cerebellar type (MSA-C)—a static posturography study
X. Li (2017)
Comparison of neutrophil–lymphocyte ratio (NLR) in Parkinson’s disease subtypes
Ceyla Ataç Uçar (2016)

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