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Yersiniosis I: Microbiological And Clinicoepidemiological Aspects Of Plague And Non-Plague Yersinia Infections

R. Smego, J. Frean, H. Koornhof
Published 1999 · Biology, Medicine

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The nature of a microorganism may be so fascinating and intellectually appealing that individuals are drawn to try and unravel the mysteries of its microbial past, present and future. Such would seem to be the case with the charismatic yersiniae as described by Bottone [1, 2]. Basic laboratory and clinicoepidemiologic investigations over the past two decades have sought to unravel the keys to the pathogenesis of these prototypic invasive and immunogenic pathogens. We have learned much about the molecular biological basis of yersinia, witnessed an evolving epidemiology of transmission and drug resistance capabilities, categorized the remarkable array of clinical manifestations caused by its human disease-causing species, and compared the historical contribution of yersiniae to the misery and suffering of mankind to the present-day scourges, tuberculosis and acquired immunodeficiency syndrome (AIDS).
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