Online citations, reference lists, and bibliographies.
← Back to Search

Headaches Add To The Burden Of Epilepsy

Marte Syvertsen, G. Helde, L. Stovner, E. Brodtkorb
Published 2007 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
The objective was to investigate and classify headaches in 109 consecutive adult patients with epilepsy. A semi-structured interview was performed in those who confirmed such symptoms (65%). Interictal headaches were present in 52%; 20% had interictal migraine. Postictal headache was reported in 44%. Migraine characteristics were present in 42% of these, and most of them (74%) also suffered from interictal migraine. Six percent had preictal headache. In partial epilepsy, there was an association between headache lateralisation and interictal EEG abnormalities (p=0.02). We conclude that headache, including migraine, is very common in patients with epilepsy. Unilateral headache may represent a lateralising sign in focal epilepsy. Seizures often trigger postictal headaches with migraine features, which often are associated with interictal migraine. Migrainous headaches sometimes proceed into epileptic seizures. The comorbidity of migraine and epilepsy should receive ample clinical attention, as it may influence antiepileptic drug choice, and the headache may need specific treatment.
This paper references
10.1212/01.wnl.0000188820.17776.cd
Preictal headache in partial epilepsy
A. Yankovsky (2005)
10.1046/j.1526-4610.2002.02154.x
Headache Associated with Epileptic Seizures: Epidemiology and Clinical Characteristics
S. Foerderreuther (2002)
10.1016/0896-6974(96)00004-7
Frequency and characteristics of interictal headaches in patients with epilepsy
M. Ito (1996)
10.1055/S-2004-815831
Comorbidity headache and epilepsy in childhood.
Yamane‚ Le (2004)
10.1111/j.1528-1157.1989.tb05291.x
Experience with the International League Against Epilepsy Proposals for Classification of Epileptic Seizures and the Epilepsies and Epileptic Syndromes in a Pediatric Outpatient Epilepsy Clinic
J. Eslava-Cobos (1989)
10.1212/WNL.43.12.2476
Migraine‐related seizures in adults with epilepsy, with EEG correlation
D. Marks (1993)
10.1046/J.1468-2982.1999.1909797.X
Migraine-Related Seizures in an Epileptic Population
SK Veliog;lu (1999)
Mulit-center study on post-ictal headache in patients with localizationrelated epilepsy
M Ito (2002)
10.1111/j.1468-2982.2004.00628.x
Characteristics of Postictal Headache in Patients with Partial Epilepsy
M. Ito (2004)
[Epilepsy and migraine].
L. Badalian (1969)
10.1002/ana.20778
Suppression of cortical spreading depression in migraine prophylaxis
C. Ayata (2006)
10.1212/WNL.44.11.2105
Comorbidity of migraine and epilepsy
R. Ottman (1994)
10.1055/s-2004-815831
Comorbidity headache and epilepsy in childhood.
L. Yamane (2004)
10.1212/WNL.56.1.130
Lateralizing value of peri-ictal headache: A study of 100 patients with partial epilepsy
A. Bernasconi (2001)
10.1016/0896-6974(94)00007-M
Self-reported characteristics of postictal headaches
S. Schachter (1995)
10.1111/j.1528-1157.1989.tb05316.x
Proposal for Revised Classification of Epilepsies and Epileptic Syndromes
K. Yoshimura (1994)
10.1159/000048105
A Case of Pheochromocytoma with Renal Artery Stenosis and Post-Surgical Watery Diarrhea
C. Blasi (2001)
Epilepsy and migraine. Epilepsy Behav 4 (Suppl 2):S13–24
ME Bigal (2003)
10.1016/S1474-4422(03)00590-8
The International Classification of Headache Disorders: 2nd edition
J. Olesen (2003)
10.1212/WNL.47.4.1104
Use of sumatriptan in post-ictal migraine headache
J. Jacob (1996)
10.1111/j.1468-2982.2005.00912.x
The Impact of Migraine on Epilepsy: A Prospective Prognosis Study
SK Veliog;lu (2005)
10.1046/j.1528-1157.2001.35100.x
Proposal for a New Classification of Outcome with Respect to Epileptic Seizures Following Epilepsy Surgery
H. Wieser (2001)
10.1002/ana.10674
Novel mutations in the Na+, K+‐ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions
K. R. Vanmolkot (2003)
10.1111/J.1468-2982.2004.00711.X
A Report on the Journal 2004
P. Goadsby (2004)
10.1046/j.1440-1819.2003.01136.x
Multi‐center study on post‐ictal headache in patients with localization‐related epilepsy
M. Ito (2003)
10.1136/jnnp.51.4.596
Post epileptic headache and migraine.
R. D'alessandro (1988)
10.1046/j.1468-2982.2000.00145.x
Prevalence of Migraine and Non-Migrainous Headache—Head-HUNT, A Large Population-Based Study
K. Hagen (2000)
10.1046/j.1526-4610.2003.03111.x
Clinical Characteristics of Patients With Comorbidity of Migraine and Epilepsy
T. Leniger (2003)
10.1111/j.1528-1167.2005.64804.x
Characteristics of Headache Associated with Intractable Partial Epilepsy
A. Yankovsky (2005)
Antiepileptic drugs: indications other than epilepsy.
E. Spina (2004)
10.1017/S0317167100033771
Migraine-like symptoms triggered by occipital lobe seizures: response to sumatriptan.
A. Ogunyemi (1998)
10.1016/j.yebeh.2003.07.003
Epilepsy and migraine
M. Bigal (2003)
10.1055/S-2004-813350
The International Classification of Headache Disorders: 2nd edition.
P. Westerhuis (2004)
10.1111/j.1526-4610.2008.01121.x
The International Classification of Headache Disorders
J. Olesen (2008)
10.1046/j.1528-1157.2001.37500.x
Seizure‐Associated Headache in Epilepsy
T. Leniger (2001)
The impact of migraine on epilepsy: a prospective prognosis study
SK Velioglu (2005)
10.1034/j.1600-0404.2000.102002129.x
Clinical factors associated with post‐ictal headache in patients with epilepsy
M. Ito (2000)
10.1053/seiz.1999.0308
A comparison of post-ictal headache between patients with occipital lobe epilepsy and temporal lobe epilepsy
M. Ito (1999)
10.1053/seiz.2001.0583
Seizure-related headache in patients with epilepsy
F. Karaali-Savrun (2002)
10.1016/j.yebeh.2005.06.008
A structured, nurse-led intervention program improves quality of life in patients with epilepsy: A randomized, controlled trial
G. Helde (2005)
10.1046/j.1528-1157.2001.22001.x
Glossary of Descriptive Terminology for Ictal Semiology: Report of the ILAE Task Force on Classification and Terminology
W. Blume (2001)



This paper is referenced by
10.17712/nsj.2019.4.20190026
Hypsarrhythmia and spasms resolution after Valproic acid discontinuation in an infantile spasm patient.
Mohammed Alsallumi (2019)
10.1080/2331205X.2017.1312791
Narcolepsy, cataplexy, hypocretin and co-existing other health complaints: A review
S. Gauci (2017)
10.1007/978-1-84882-128-6_93
Migraine, Migralepsy and Basilar Migraine
S. Haut (2010)
10.5220/0002750204470451
EEG Signals in Epilepsy and Migraine - Analysis and Simulations by Multi-agent Systems
A. Viganó (2010)
10.1007/s11916-013-0351-x
Headache and Epilepsy
P. Bauer (2013)
10.1016/j.jns.2011.04.006
Headache among mesial temporal lobe epilepsy patients: A case-control study
J. Nunes (2011)
10.4172/NEUROPSYCHIATRY.1000398
Incidence and Characteristics of Headaches in a Retrospective Cohort of Taiwanese Children with Focal Epilepsy
I. Lee (2018)
HEADACHE ON EPILEPTIC PATIENTS
I. Made (2013)
10.1007/s10309-017-0158-6
Kopfschmerzen bei Epilepsie
U. Ermis (2017)
10.1111/j.1468-1331.2008.02353.x
Comorbidity of migraine and epilepsy in a Norwegian community
E. Brodtkorb (2008)
10.1016/S1474-4422(18)30085-1
International Classification of Headache Disorders
J. Olesen (2018)
10.17169/refubium-11237
Periiktaler und interiktaler Kopfschmerz bei Patienten mit Epilepsie
Beate geb. Wawrzyniak Duchaczek (2011)
10.1016/j.jfma.2011.08.022
ADHD-related symptoms, emotional/behavioral problems, and physical conditions in Taiwanese children with epilepsy.
Fang-Ju Tsai (2013)
10.21474/IJAR01/3256
JUVENILE MYOCLONIC EPILEPSY AND MIGRAINE: STUDY OF COMORBIDITY AND CLINICAL CO-OCCURRENCE.
Saleh Atteya (2017)
10.1212/WNL.0b013e3182617113
Comorbidity of migraine in children presenting with epilepsy to a tertiary care center
S. Kelley (2012)
10.1523/JNEUROSCI.0283-20.2020
Activation of Peripheral and Central Trigeminovascular Neurons by Seizure: Implications for Ictal and Postictal Headache
A. Melo-Carrillo (2020)
10.1177/0333102410370876
Postictal headache in South African adult patients with generalised epilepsy in a tertiary care setting: A cross-sectional study
S. Botha (2010)
10.1007/s00415-014-7391-y
Adverse events of placebo-treated, drug-resistant, focal epileptic patients in randomized controlled trials: a systematic review
G. Zaccara (2014)
10.1016/j.yebeh.2017.03.009
Epilepsy and headaches: Further evidence of a link
Asli Ece Çilliler (2017)
10.14800/MCE.197
Postictal headache in epileptic patients
Xiangqing Wang (2014)
10.1016/j.meatsci.2011.11.039
A perspective on the electrical stunning of animals: are there lessons to be learned from human electro-convulsive therapy (ECT)?
A. Zivotofsky (2012)
10.1007/S11916-008-0063-9
Secondary intracranial causes for headaches in children
R. Ahad (2008)
10.1016/j.yebeh.2018.08.035
New-onset interictal headache in Persons with epilepsy (PWE): A case–control study
Jashobanta Sahu (2018)
10.1016/j.eplepsyres.2013.12.013
Comorbidity between headache and epilepsy in a Chinese epileptic center
Xiang-Qing Wang (2014)
10.1016/j.yebeh.2012.09.025
“Headache and epilepsy” — How are they connected?
L. Papetti (2013)
10.1016/j.nrl.2011.10.016
Links between headaches and epilepsy: current knowledge and terminology.
A. Caminero (2014)
10.1007/s10072-017-3232-y
Prevalence and clinical characteristics of headache in juvenile myoclonic epilepsy: experience from a tertiary epilepsy center
Metin Dedei Daryan (2017)
10.1111/epi.12972
Prevalence and etiology of epilepsy in a Norwegian county—A population based study
M. Syvertsen (2015)
10.4236/JBBS.2019.93012
Clinical Characteristics of Headache in Egyptian Patients with Idiopathic Epilepsy
Mohamed A. Sayed (2019)
10.1002/9781444394047
Comorbidity in migraine
J. Schoenen (2011)
10.1016/J.NRL.2011.10.016
Vínculos existentes entre cefalea y epilepsia: terminología y conceptos actuales
A. Caminero (2014)
10.1002/epi4.12363
Headache in epilepsy: A prospective observational study
Mark A Whealy (2019)
See more
Semantic Scholar Logo Some data provided by SemanticScholar