Online citations, reference lists, and bibliographies.
← Back to Search

Antitumor And Antimetastatic Activity Of Fucoidan, A Sulfated Polysaccharide Isolated From The Okhotsk Sea Fucus Evanescens Brown Alga

T. V. Alekseyenko, S. Y. Zhanayeva, A. A. Venediktova, T. Zvyagintseva, T. Kuznetsova, N. Besednova, T. Korolenko
Published 2007 · Chemistry, Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
Antitumor and antimetastatic activities of fucoidan, a sulfated polysaccharide isolated from Fucus evanescens (brown alga in Okhotsk sea), was studied in C57Bl/6 mice with transplanted Lewis lung adenocarcinoma. Fucoidan after single and repeated administration in a dose of 10 mg/kg produced moderate antitumor and antimetastatic effects and potentiated the antimetastatic, but not antitumor activities of cyclophosphamide. Fucoidan in a dose of 25 mg/kg potentiated the toxic effect of cyclophosphamide.
This paper references



This paper is referenced by
AMELIORATIVE EFFECT OF RED ALGAE ACANTHOPHORA SPICIFERA AGAINST PUFFER FISH AROTHRON HISPIDUS INDUCED BIOCHEMICAL AND OXIDATIVE STRESS IN MICE.
K. Mohana Priya (2013)
Environmental Eco-Friendly Marine Resource Macro Algae (Seaweeds): An Omnipotent Source for Value Added Products and its Applications
Balasubramaniyan Bharathiraja (2016)
10.1134/S1063074009020084
Comparative study of chemical composition and antitumor activity of aqueous-ethanol extracts of brown algae Laminaria cichorioides, Costaria costata, and Fucus evanescens
T. Imbs (2009)
10.1371/journal.pone.0043483
Anticancer Properties and Mechanisms of Fucoidan on Mouse Breast Cancer In Vitro and In Vivo
Meilan Xue (2012)
10.3390/md18090476
Marine Cyanobacteria and Microalgae Metabolites—A Rich Source of Potential Anticancer Drugs
Arijit Mondal (2020)
10.1039/C5RA23995H
A review of the components of brown seaweeds as potential candidates in cancer therapy
Ejaz Hussain (2016)
10.1007/978-981-10-1950-0_10
Algae as Source of Food and Nutraceuticals
Katarzyna Godlewska (2017)
10.2174/1381612825666190425155126
Molecular Mechanisms Underlying Cancer Preventive and Therapeutic Potential of Algal Polysaccharides.
Soraya Sajadimajd (2019)
Anti-Proliferation Activity of Fucoidan in MKN45 Gastric Cancer Cells and Downregulation of Phosphorylated ASK1, a Cell Cycle-Regulated Kinase
M. Yoshimoto (2015)
10.1016/j.biopha.2018.12.069
Microalgae in modern cancer therapy: Current knowledge.
M. A. Abd El-Hack (2019)
10.1016/J.CARBPOL.2011.07.032
Structural characterization of a sulfated glucan isolated from the aqueous extract of Hedysarum polybotrys Hand.-Mazz
Yikai Shi (2012)
Study of Fucoidan Digestibility via an in Vitro Digestion System
Yuanyang Cao (2015)
10.1016/j.ijbiomac.2018.04.163
Investigation of antioxidant and anticancer potential of fucoidan from Sargassum polycystum.
Subramanian Palanisamy (2018)
10.1002/mc.22236
Low fucose containing bacterial polysaccharide facilitate mitochondria‐dependent ROS‐induced apoptosis of human lung epithelial carcinoma via controlled regulation of MAPKs‐mediated Nrf2/Keap1 homeostasis signaling
S. R. Chowdhury (2015)
10.3892/etm.2013.1368
Fucoidan induces caspase-dependent apoptosis in MC3 human mucoepidermoid carcinoma cells
Hangeun Lee (2014)
10.1016/j.rvsc.2018.04.007
Fucoidan suppresses excessive phagocytic capacity of porcine peripheral blood polymorphonuclear cells by modulating production of tumor necrosis factor-alpha by lipopolysaccharide-stimulated peripheral blood mononuclear cells.
Hyeong-Mok Kim (2018)
SCREENING OF ANTI-OXIDANT ACTIVITY OF METHANOLIC EXTRACT OF GRACILARIA FERGUSONII J.AG. (RED SEAWEED) IN HARE ISLAND, THOOTHUKUDI, TAMIL NADU, INDIA
Iniya Udhaya (2017)
10.3390/md12020851
Fucoidan as a Marine Anticancer Agent in Preclinical Development
J. Kwak (2014)
10.1016/j.ijbiomac.2013.06.030
Brown seaweed fucoidan: biological activity and apoptosis, growth signaling mechanism in cancer.
K. Senthilkumar (2013)
10.3390/md13074398
Purification and Characterization of a Fucoidanase (FNase S) from a Marine Bacterium Sphingomonas paucimobilis PF-1
Woo Jung Kim (2015)
10.1139/y11-093
Antioxidant, anti-inflammatory, and antiproliferative activities of organic fractions from the Mediterranean brown seaweed Cystoseira sedoides.
Lamia Mhadhebi (2011)
10.1016/j.algal.2020.101884
Antitumoral effects of fucoidan on bladder cancer
C.C.F. do-Amaral (2020)
10.1007/s10517-014-2719-2
Effect of Biologically Active Substances Derived from Hydrobionts of the Pacific Ocean on Parameters of Lipid Metabolism during Experimental Hypercholesterolemia
T A Kuznetsova (2014)
10.1016/j.ijbiomac.2019.11.191
"Fucoidan, a natural biopolymer in cancer combating: From edible algae to nanocarrier tailoring".
Samar M. Etman (2019)
10.1016/B978-0-12-809816-5.00010-4
Fucoidans: Anticancer Activity and Molecular Mechanisms of Action
O. Malyarenko (2017)
Fucoidan as a Marine Anticancer Agent in
Jong-Young Kwak (2014)
10.15171/JHP.2018.37
Isolation, characterisation and in vitro screening of anticataract potential of Fucoidan from Sargassum wightii Greville
Sathiya Ramu (2018)
10.1007/s10811-010-9632-5
Bioactive compounds in seaweed: functional food applications and legislation
S. L. Holdt (2010)
10.1021/IE400527B
Microwave–Hydrothermal Extraction and Degradation of Fucoidan from Supercritical Carbon Dioxide Deoiled Undaria pinnatifida
A. Quitain (2013)
10.1016/J.PHYTOL.2015.09.007
Bioactive compounds from brown seaweeds: Phloroglucinol, fucoxanthin and fucoidan as promising therapeutic agents against breast cancer
D. Padua (2015)
10.1016/j.tiv.2010.06.018
A glycoprotein from Laminaria japonica induces apoptosis in HT-29 colon cancer cells.
Hiroe Go (2010)
10.1007/978-1-4614-1247-2_1
Taxonomy of Marine Macroalgae Used as Sources of Bioactive Compounds
F. Rindi (2012)
See more
Semantic Scholar Logo Some data provided by SemanticScholar