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Expression Of Peroxiredoxin 1, 2, 3, And 6 Genes In Cancer Cells During Drug Resistance Formation

E. Kalinina, T. Berezov, A. Shtil, N. Chernov, V. Glazunova, M. Novichkova, N. Nurmuradov
Published 2012 · Biology, Medicine

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We studied the expression of peroxiredoxin genes (PRDX1, PRDX2, PRDX3, and PRDX6) in human erythroleukemia K652, human breast carcinoma MCF-7, and human ovarian carcinoma SKOV-3 cells during cisplatin resistance development. It was found that drug resistance formation was accompanied by a significant increase in the expression of PRDX1, PRDX2, PRDX3, PRDX6 genes in all cancer cell strains, which confirms the important contribution of redox-dependent mechanisms into the development of cisplatin resistance of cancer cells.
This paper references
Br. J. Cancer
M. Gerretsen (1993)
Role of reactive oxygen species in cis-dichlorodiammineplatinum-induced cytotoxicity on bladder cancer cells.
A. Miyajima (1997)
Role of Peroxiredoxins in Regulating Intracellular Hydrogen Peroxide and Hydrogen Peroxide-induced Apoptosis in Thyroid Cells*
H. Kim (2000)
J. Biol. Chem
H Kim (2000)
Overexpression of peroxiredoxin in human breast cancer.
D. Y. Noh (2001)
Anticancer Res
D Y Noh (2001)
Biol. Chem
B Hofmann (2002)
Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling
Z. Wood (2003)
Role of Nrf2 in the Regulation of CD36 and Stress Protein Expression in Murine Macrophages: Activation by Oxidatively Modified LDL and 4-Hydroxynonenal
Tetsuro Ishii (2004)
Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review).
G. Wang (2004)
Circ. Res
T Ishii (2004)
Oncol. Rep
G Wang (2004)
Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism.
Y. Manevich (2005)
Biol. Med
Y Manevich (2005)
Oxidative Stress. Prooxidants and Antioxidants [in Russian]
E B Men 'shikova (2006)
Selected flavonoids potentiate the toxicity of cisplatin in human lung adenocarcinoma cells: a role for glutathione depletion.
R. Kachadourian (2007)
Int. J. Oncol
R Kachadourian (2007)
Peroxiredoxin 6: a bifunctional enzyme with glutathione peroxidase and phospholipase A₂ activities.
A. Fisher (2011)
Peroxiredoxin 6 Overexpression Attenuates Cisplatin-Induced Apoptosis in Human Ovarian Cancer Cells
J. Pak (2011)
Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H₂O₂, and protein chaperones.
S. Rhee (2011)
Mitochondrial Peroxiredoxin III is a Potential Target for Cancer Therapy
I. Song (2011)
Cancer Invest
J H Pak (2011)
Antioxid. Redox. Signal
A B Fisher (2011)
Antioxid. Redox. Signal
S G Rhee (2011)
Int. J. Mol. Sci
G. An (2014)

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