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Health-Related Quality Of Life, Sexuality And Hormone Status After Laparoscopic Roux-En-Y Gastric Bypass In Women

Rebecca Paul, Ellen Andersson, Mikael Wirén, Jessica Frisk
Published 2019 · Medicine
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Objective Few studies have been carried out concerning the influence of bariatric surgery on female sexuality and hormones, particularly utilizing hormone-based questionnaires. The effect of bariatric surgery on sex hormone levels, sexual function and health-related quality of life (HRQL) in women was analyzed in this study. Participants were included in a single-center study at a regional hospital in Sweden, with a duration of one-year follow-up. Methods One hundred non-smoking women, undergoing laparoscopic Roux-en-Y gastric bypass, were included in the study. Blood assay for sex-hormone binding globulin (SHBG), testosterone, estrogen, progesterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) was analyzed. Participants completed the Female Sexual Function Index (FSFI), Women’s Health Questionnaire (WHQ) and Psychological General Well-being Inventory (PGWB) parallel to lab testing. Results At one-year follow-up, several significant results were found concerning hormones and questionnaires. Testosterone decreased and SHBG increased, N  = 68/100. Desire, arousal, orgasm, satisfaction and total score domains for the FSFI increased after one year, N  = 53/100. WHQ domains concerning depressed mood, somatic symptoms, memory, anxiety, sexual behavior and attractiveness improved after one year, N  = 47/100. All domains in the PGWB ( N  = 52), including anxiety, depressed mood, positive well-being, self-control, general health, vitality and total score improved at follow-up. Spearman’s Rho coefficient analysis found correlation between testosterone/WHQ-sexual problems (0.3), SHBG/WHQ-general health (0.3) and SHBG/FSFI-arousal (−0.3). Conclusions Bariatric surgery normalizes levels of sex-hormones in women, and results in improved sexual function, health-related quality of life and psychological well-being.
This paper references
10.1007/BF03344053
Adrenal and gonadal function in obesity
Renato Pasquali (2002)
10.1001/jamasurg.2013.5022
Changes in sexual functioning and sex hormone levels in women following bariatric surgery.
David B Sarwer (2014)
10.1016/0960-0760(95)00108-C
Sex hormone-binding globulin and female reproductive function
Nicholas Botwood (1995)
10.1055/s-2007-978681
Sex steroid hormones, sex hormone-binding globulin, and obesity in men and women.
André Tchernof (2000)
10.1038/oby.2006.62
Obesity and sexual quality of life.
Ronette L Kolotkin (2006)
10.1007/s11695-017-3025-7
4-Year Changes in Sex Hormones, Sexual Functioning, and Psychosocial Status in Women Who Underwent Bariatric Surgery
David B Sarwer (2017)
10.1007/s11695-012-0588-1
A Review of the Relationships Between Extreme Obesity, Quality of Life, and Sexual Function
David B Sarwer (2012)
10.1055/s-0032-1328880
The impact of bariatric surgery on obesity-related infertility and in vitro fertilization outcomes.
Orkun Tan (2012)
10.1016/j.yhbeh.2011.03.013
Sexual desire, sexual arousal and hormonal differences in premenopausal US and Dutch women with and without low sexual desire
Julia R. Heiman (2011)
10.1016/j.socscimed.2015.12.024
"When the honeymoon is over, the real work begins:" Gastric bypass patients' weight loss trajectories and dietary change experiences.
Amanda Lynch (2016)
10.1152/physrev.00033.2011
Pathophysiology of human visceral obesity: an update.
André Tchernof (2013)
10.1001/jamasurg.2018.1162
Changes in Sexual Functioning in Women and Men in the 5 Years After Bariatric Surgery.
Kristine J. Steffen (2019)
10.1038/sj.ijir.3901548
Association of body weight with sexual function in women
Katherine Esposito (2007)
10.1007/s40618-014-0169-3
Functional hypothalamic amenorrhea and its influence on women’s health
Blazej Meczekalski (2014)
10.4239/wjd.v3.i4.71
Defining the role of bariatric surgery in polycystic ovarian syndrome patients.
Shaveta M Malik (2012)
10.1016/j.soard.2018.02.009
Long-term follow-up of disease-specific quality of life after bariatric surgery.
Simon Biron (2018)
10.1080/09513590.2016.1236243
The impact of gastric bypass surgery on sex hormones and menstrual cycles in premenopausal women
Mette Mandrup Kjær (2017)
The psychological general well-being (PGWB) index
HJ Dupuy (1984)
10.1016/j.fertnstert.2009.08.028
Reproductive health of women electing bariatric surgery.
Gabriella G. Gosman (2010)
10.1016/j.soard.2010.05.015
Significant resolution of female sexual dysfunction after bariatric surgery.
Dale S Bond (2011)
10.1007/s13679-017-0266-7
Quality of Life After Bariatric Surgery
Laura M. Mazer (2017)
10.1016/j.yhbeh.2015.11.003
Increasing women's sexual desire: The comparative effectiveness of estrogens and androgens
Maurand Cappelletti (2016)
10.1530/endoabs.41.EP819
Changes in testosterone levels and sex hormone-binding globulin levels in extremely obese men after bariatric surgery
Patchaya Boonchaya-anant (2016)
10.1038/oby.2008.641
Obesity and menstrual irregularity: associations with SHBG, testosterone, and insulin.
Shuying Wei (2009)
10.1016/j.soard.2012.01.011
Six-year changes in health-related quality of life in gastric bypass patients versus obese comparison groups.
Ronette L Kolotkin (2012)
10.1016/j.soard.2016.09.022
Sexual functioning of men and women with severe obesity before bariatric surgery.
Kristine J. Steffen (2017)
The women's health questionnaire: a measure of midaged women's perceptions of their emotional and physical health
M. Hunter (1992)
10.1007/s11695-012-0823-9
Reduced Circulating Androgen Levels After Gastric Bypass Surgery in Severely Obese Women
Barbara van Ernst (2012)
10.1080/009262300278597
The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function.
Raymond C. Rosen (2000)
10.1007/s11695-015-1729-0
Roux-en-Y Gastric Bypass Surgery in Patients with Polycystic Ovary Syndrome and Metabolic Syndrome
Sahruh Turkmen (2015)
10.3389/fphys.2018.01834
Effect of Estrogen on Musculoskeletal Performance and Injury Risk
Nkechinyere Chidi-Ogbolu (2019)
10.3109/00016349309021159
A Swedish version of the Women's Health Questionnaire. A measure of postmenopausal complaints.
Ingela K Wiklund (1993)
10.1080/08870449208404294
The women's health questionnaire: A measure of mid-aged women's perceptions of their emotional and physical health
Myra S Hunter (1992)



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