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Exploring Bioactive Compounds In Anaerobically Digested Slurry: Extraction, Characterization, And Assessment Of Antifungal Activity

Jiaxin Lu, Atif Muhmood, Hong-tao Liu, R. Dong, S. Pang, Shubiao Wu
Published 2020 · Chemistry

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Anaerobically digested slurry is well known for its use as a bio-fertilizer because of its high macro-nutrient content (e.g. N, P, K), which is essential for plant growth. The suppressive effect of slurry land application on pathogenic fungal growth due to the presence of bioactive and antimicrobial substances generated during anaerobic digestion has recently been reported. However, knowledge about the identification, characterization, and subsequent antimicrobial activity evaluation of various bioactive compounds in the anaerobically digested slurry is still insufficient. Ultrasound-assisted extraction using three solvents, ethyl acetate (EA), dichloromethane (DM), and n -butanol (NB), was employed for extraction of bioactive compounds. After extraction and characterization, antifungal activity against Fusarium oxysporum was assessed. EA was found to be a more efficient extractant with less evaporating time (4 min), irrespective of temperature. DM was found to be efficient in the extraction of O-heterocycles, while N-heterocycles were enriched in EA extracts. Furthermore, the bioactive compounds, 1,2-benzenedicarboxylic acid, butyl 2-methylpropyl ester (54.9%), and 9-octadecenamide, (Z)-(2.51%) were detected in the EA extract, while tetrahydro-2-furanmethanamine (1.32%), cyclic octatomic sulfur (1.17%), squalene (4.06%), and cholestan-3-ol (9.06%) were detected in the DM extract. The EA extract achieved approximately 84% inhibition of F. oxysporum , while only 63% inhibition was observed with the DM extract. Collectively, these findings indicate that in addition to its role as a fertilizer, digested slurry may also contribute to the control of phytopathogens upon land application because of the presence of various bioactive compounds. However, further work is needed to explore the diversity of bioactive compounds in digested manures and evaluate their antimicrobial potential. Graphical Abstract
This paper references
10.1021/TX015508+
Synthesis of new carboxylesterase inhibitors and evaluation of potency and water solubility.
C. Wheelock (2001)
10.1021/AR010071I
Unsaturated O- and N-heterocycles from carbohydrate feedstocks.
F. W. Lichtenthaler (2002)
10.1016/J.FITOTE.2005.02.002
Preliminary assay on the radical scavenging activity of olive wood extracts.
J. Altarejos (2005)
10.1016/J.CHROMA.2005.12.055
Isolation and identification of radical scavengers in olive tree (Olea europaea) wood.
M. Pérez-Bonilla (2006)
10.1080/03601230601020944
The conversion of chicken manure to biooil by fast pyrolysis II. Analysis of chicken manure, biooils, and char by curie-point pyrolysis-gas chromatography/mass spectrometry (Cp Py-GC/MS)
Morris I Schnitzer (2007)
10.1016/J.APSOIL.2006.09.011
Soil enzyme activities, microbial community composition and function after 47 years of continuous green manuring
Sara Elfstrand (2007)
10.17660/ACTAHORTIC.2008.776.16
The potential of biological soil disinfestation to manage Fusarium foot and root rot in Asparagus
W. Blok (2008)
10.3390/molecules14062167
Effect of Extraction Solvent/Technique on the Antioxidant Activity of Selected Medicinal Plant Extracts
B. Sultana (2009)
10.1007/s00216-008-2512-z
Characterization of volatile and semivolatile compounds in waste landfill leachates using stir bar sorptive extraction–GC/MS
L. Badoil (2009)
10.1016/j.chroma.2008.11.076
Determination of four heterocyclic insecticides by ionic liquid dispersive liquid-liquid microextraction in water samples.
Y. Liu (2009)
10.1007/s10705-010-9346-8
Effects of organic wastes digestion for biogas production on mineral nutrient availability of biogas effluents
K. Moeller (2010)
10.1016/j.biortech.2010.04.073
Fractionation and identification of organic nitrogen species from bio-oil produced by fast pyrolysis of sewage sludge.
Jing-Pei Cao (2010)
Synthesis and Antimicrobial Activity of New Indole Derivatives
K. Nataraj (2010)
10.1016/j.chroma.2011.07.102
Comparison of the performance of conventional, temperature-controlled, and ultrasound-assisted ionic liquid dispersive liquid-liquid microextraction combined with high-performance liquid chromatography in analyzing pyrethroid pesticides in honey samples.
Jiaheng Zhang (2011)
10.1016/j.ejmech.2011.09.023
1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study.
Tarunkumar Nanjibhai Akhaja (2011)
Physical and chemical characteristics of anaerobically digested slurry from large-scale biogas project in Jiangsu Province.
Jin Hong-mei (2011)
10.3923/JM.2011.270.280
Diversity, Pathogenicity and Toxicology of A. niger: An Important Spoilage Fungi
A. K. Gautam (2011)
10.1016/J.BIOMBIOE.2012.04.010
Co-composting of the solid fraction of anaerobic digestates, to obtain added-value materials for use in agriculture
M. Bustamante (2012)
10.1016/j.biortech.2012.02.059
Petroleum and polycyclic aromatic hydrocarbons (PAHs) degradation and naphthalene metabolism in Streptomyces sp. (ERI-CPDA-1) isolated from oil contaminated soil.
C. Balachandran (2012)
10.1007/s00374-012-0719-9
Soil C and N mineralisation and agricultural value of the products of an anaerobic digestion system
C. D. L. Fuente (2012)
10.1002/jssc.201200431
Methodological aspects of sample preparation for the determination of carbamate residues: a review.
Y. Santaladchaiyakit (2012)
10.4103/0974-8490.91028
GC-MS analysis of phytocomponents in the ethanol extract of Polygonum chinense L
B. Ezhilan (2012)
10.1016/J.FUEL.2012.12.093
Organonitrogen compounds identified in degraded wheat straw by oxidation in a sodium hypochlorite aqueous solution
Y. Lu (2013)
10.1016/J.BIOCONTROL.2013.10.008
Biological control of plant pathogens by microorganisms isolated from agro-industrial composts
F. Suárez-Estrella (2013)
10.1155/2013/719593
Effect of Extraction Conditions on the Antioxidant Activity of Olive Wood Extracts
M. Pérez-Bonilla (2013)
10.1002/JHET.1123
Synthesis of Some New Benzo[b][1,4]diazepine Based Heterocycles
I. El-Azab (2013)
10.1007/s00216-013-7344-9
Dispersive liquid–liquid microextraction in food analysis. A critical review
P. Viñas (2013)
10.1016/J.CROPRO.2013.03.004
The use of liquid swine manure for the control of potato cyst nematode through soil disinfestation in laboratory conditions
J. Lopez-Robles (2013)
10.1016/J.DESAL.2013.07.010
Concentrating process of liquid digestate by disk tube-reverse osmosis system
H. Gong (2013)
10.1007/s10098-013-0640-4
Anaerobic fermentation by aquatic product wastes and other auxiliary materials
Aimin Liu (2013)
10.1016/J.FUEL.2013.04.064
Molecular characterization of nitrogen-containing species in switchgrass bio-oils at various harvest times
D. Cole (2013)
10.1016/j.biortech.2013.01.052
The fate of antagonistic microorganisms and antimicrobial substances during anaerobic digestion of pig and dairy manure.
Y. Cao (2013)
10.3390/molecules19022166
Synthesis, Biological Evaluation and Structure-Activity Relationships of New Quinoxaline Derivatives as Anti-Plasmodium falciparum Agents
A. Gil (2014)
10.1155/2014/175457
A Simple Microfluidic Chip Design for Fundamental Bioseparation
A. S. Chan (2014)
10.13031/TRANS.57.10622
Effects of Digestate from Swine Manure Digester on in Vitro Growth of Crop Fungal Pathogens: A Laboratory Study
X. Tao (2014)
10.1155/2014/150509
Isolation and Bioactivity Analysis of Ethyl Acetate Extract from Acer tegmentosum Using In Vitro Assay and On-Line Screening HPLC-ABTS+ System
K. Lee (2014)
10.1007/s11707-014-0411-5
Ecological analysis of a typical farm-scale biogas plant in China
Na Duan (2014)
Biogas residues - aspects of nutrient management and soil fertility
B. Eichler-Loebermann (2014)
10.1021/cr300122t
Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings.
P. Majumdar (2014)
10.1021/ACSSUSCHEMENG.5B00841
Renewable N-Heterocycles Production by Thermocatalytic Conversion and Ammonization of Biomass over ZSM-5
L. Xu (2015)
10.1016/J.SOILBIO.2015.02.006
Manure-based biogas fermentation residues – Friend or foe of soil fertility?
H. Insam (2015)
10.1007/s13593-015-0284-3
Effects of anaerobic digestion on soil carbon and nitrogen turnover, N emissions, and soil biological activity. A review
K. Moeller (2015)
Design and synthesis of potentially antibiofilm active compounds based on 2-aminoimidazoles and related structures
T. Tran (2015)
10.4137/CMO.S26067
Treating Elderly Patients With Hormone Receptor–Positive Advanced Breast Cancer
David Riseberg (2015)
10.5897/AJBX2014.14292
Bayoud disease of date palm in Algeria: History, epidemiology and integrated disease management
Ie Benzohra (2015)
10.1016/j.scitotenv.2015.02.009
Evaluation of hormone-like activity of the dissolved organic matter fraction (DOM) of compost and digestate.
B. Scaglia (2015)
10.1039/C5EE01633A
New opportunities for agricultural digestate valorization: current situation and perspectives
F. Monlau (2015)
10.3109/19401736.2013.869675
Haplotypes and variable position detection in the mitochondrial DNA coding region encompassing nucleotide positions 10,716–11,184
I. Hameed (2015)
10.1016/j.biortech.2016.07.125
The influence of flue gas desulphurization gypsum additive on characteristics and evolution of humic substance during co-composting of dairy manure and sugarcane pressmud.
Xiaobo Guo (2016)
10.1021/ACSSUSCHEMENG.5B00586
Anaerobic Digestion and Storage Influence Availability of Plant Hormones in Livestock Slurry
X. Li (2016)
10.1007/s00253-016-7571-z
The alkaloid gramine in the anaerobic digestion process—inhibition and adaptation of the methanogenic community
Denny Popp (2016)
10.4103/0975-7406.171678
Synthesis, characterization and in silico biological activity of some 2-(N,N-dimethyl guanidinyl)-4,6-diaryl pyrimidines
R. K. Kumarachari (2016)
10.1016/J.APSOIL.2016.05.010
Soil chemical and microbial responses to biogas slurry amendment and its effect on Fusarium wilt suppression
Y. Cao (2016)
10.1155/2017/9064531
Wound Myiasis Caused by Sarcophaga (Liopygia) Argyrostoma (Robineau-Desvoidy) (Diptera: Sarcophagidae): Additional Evidences of the Morphological Identification Dilemma and Molecular Investigation
A. Giangaspero (2017)
10.1016/J.ARABJC.2012.10.008
Studies on synthesis of pyrimidine derivatives and their antimicrobial activity
C. Mallikarjunaswamy (2017)
10.1155/2017/1207061
In Vitro Antifungal Activity of Hexahydropyrimidine Derivatives against the Causative Agents of Dermatomycosis
Francislene J Martins (2017)
10.1234/CT.V38I1.1330
EFECTO AGRONÓMICO DEL BIOSÓLIDO EN CULTIVO DE TOMATE (Solanum lycopersicum): CONTROL BIOLÓGICO DE Rhizoctonia solani
E. L. Dávila (2017)
Synthesis of a novel series of imines containing nitrogen heterocycles as promising antibacterial and antifungal agents
N. C. Desai (2017)
10.1016/J.INDCROP.2017.10.038
Solvent selection for efficient extraction of bioactive compounds from grape pomace
Diandra Pintać (2018)



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