Online citations, reference lists, and bibliographies.
← Back to Search

Myosin Isozyme Transitions Occurring During The Postnatal Development Of The Rat Soleus Muscle.

G. Butler-Browne, R. Whalen
Published 1984 · Biology, Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
The myosin isozymes present in the developing rat soleus muscle from 1 week to 6 weeks after birth were investigated using biochemical and immunological methods. Electrophoresis of native myosin reveals that adult slow myosin is present in the soleus as early as 1 week after birth. At this time, embryonic and neonatal myosin can also be demonstrated. Using an immunotransfer technique, the presence of slow myosin heavy chain can be demonstrated at all time points examined whereas neonatal myosin heavy chain diminishes in quantity between 2 and 3 weeks, and is undetectable in the adult soleus. Specific polyclonal antibodies were prepared to embryonic, neonatal, and adult fast and slow myosins. Immunocytochemistry reveals a cellular heterogeneity at all stages examined. Different combinations of myosin isozymes can be found in the soleus fibers depending on the stage of development; these results suggest therefore that myosin isozyme transitions are occurring. Approximately half the fibers contain embryonic and slow myosin at 1 week after birth; these fibers subsequently contain only slow myosin. A second group of fibers contains embryonic and neonatal myosin at 1 week and most of them subsequently accumulate adult fast myosin. A portion of this latter group begins to acquire slow myosin from 4 weeks of age. These data are interpreted to suggest that a preprogrammed sequence of myosin isozymes is embryonic----neonatal----adult fast. At any time during development of an individual fiber, induction of slow myosin accumulation and repression of other types can occur.
This paper references
10.1016/0022-510X(76)90001-0
Adaptive transformation of rat soleus motor units during growth: Histochemistry and contraction speed
E. Kugelberg (1976)
10.1042/BJ1570087
Electrophoretic analysis of multiple forms of myosin in fast-twitch and slow-twitch muscles of the chick.
J. F. Hoh (1976)
10.1016/0022-2836(73)90244-1
Polarity of the myosin molecule.
R. Starr (1973)
10.1083/JCB.90.1.128
Development of muscle fiber specialization in the rat hindlimb
N. Rubinstein (1981)
10.1016/0022-2836(78)90049-9
Identification of a novel form of myosin light chain present in embryonic muscle tissue and cultured muscle cells.
R. Whalen (1978)
10.1083/JCB.92.2.471
Distribution and properties of myosin isozymes in developing avian and mammalian skeletal muscle fibers
G. Gauthier (1982)
The sequential replacement of myosin subunit isoforms during muscle type transformation induced by long term electrical stimulation.
W. E. Brown (1983)
10.1111/J.1432-1033.1981.TB05347.X
Analysis of myosin light and heavy chain types in single human skeletal muscle fibers.
R. Billeter (1981)
10.1016/0012-1606(81)90396-1
Species- and age-dependent changes in the relative amounts of cardiac myosin isoenzymes in mammals.
A. Lompre (1981)
10.1002/MUS.880040204
The adaptive response of skeletal muscle to increased use
S. Salmons (1981)
10.1016/0012-1606(78)90229-4
Myogenic and neurogenic contributions to the development of fast and slow twitch muscles in rat.
N. Rubinstein (1978)
10.1113/jphysiol.1980.sp013531
selective elimination of motor nerve terminals in the rat soleus muscle during development.
Y. Miyata (1980)
10.1113/jphysiol.1979.sp013051
The size of motor units during post‐natal development of rat lumbrical muscle.
W. Betz (1979)
10.1016/0014-4886(72)90071-4
Biphasic development of muscle fibers in the fetal lamb.
C. Ashmore (1972)
10.1038/282522A0
Distribution of light chains in fast skeletal myosin
S. Lowey (1979)
10.1113/jphysiol.1974.sp010670
The formation of synapses in striated muscle during development
M. Bennett (1974)
10.1146/ANNUREV.PH.43.030181.002531
Development, innervation, and activity-pattern induced changes in skeletal muscle.
F. Jólesz (1981)
10.1001/ARCHNEUR.1967.00470290096012
Neuronal trophic function. A new aspect demonstrated histochemically in developing soleus muscle.
G. Karpati (1967)
10.1083/JCB.42.1.135
THE HISTOGENESIS OF RAT INTERCOSTAL MUSCLE
A. Kelly (1969)
10.1038/299830A0
Denervation of newborn rat muscles does not block the appearance of adult fast myosin heavy chain
G. Butler-Browne (1982)
10.1111/j.1749-6632.1979.tb56514.x
EMBRYOLOGY OF TWO MURINE MUSCLE DISEASES: MUSCULAR DYSTROPHY AND MUSCULAR DYSGENESIS * †
A. Platzer (1979)
10.1113/jphysiol.1970.sp009187
Neuromuscular transmission in new‐born rats
P. A. Redfern (1970)
10.1038/292805A0
Three myosin heavy-chain isozymes appear sequentially in rat muscle development
R. Whalen (1981)
10.1111/j.1749-6632.1974.tb20506.x
THE USE AND ABUSE OF MUSCLE HISTOCHEMISTRY
M. Brooke (1974)
10.1113/jphysiol.1976.sp011565
Polyneuronal innervation of skeletal muscle in new‐born rats and its elimination during maturation.
M. C. Brown (1976)
10.1111/J.1432-1033.1980.TB04434.X
Use of antibodies against dodecylsulfate-denatured heavy meromyosins to probe structural differences between muscular myosin isoenzymes.
K. Schwartz (1980)
10.1073/PNAS.76.10.5197
Contractile protein isozymes in muscle development: identification of an embryonic form of myosin heavy chain.
R. Whalen (1979)
10.1111/J.1432-1033.1979.TB13253.X
An electrophoretic study of native myosin isozymes and of their subunit content.
A. D'albis (1979)
10.1016/0014-4886(81)90282-X
Effect of denervation of neonatal rat sciatic nerve on the differentiation of myosin in a single muscle fiber
S. Ishiura (1981)
10.1038/280321A0
Rabbit skeletal myosin isoenzymes from fetal, fast-twitch and slow-twitch muscles
J. Hoh (1979)
10.1038/298294A0
Fetal myosin heavy chains in regenerating muscle
S. Sartore (1982)



This paper is referenced by
10.1007/1-4020-5177-8_3
Striated Muscle Plasticity: Regulation of the Myosin Heavy Chain Genes
F. Haddad (2006)
10.1165/AJRCMB/6.3.335
Myosin heavy chain expression in respiratory muscles of the rat.
W. LaFramboise (1992)
10.1016/0960-8966(91)90004-C
Myosin isoform transitions and physiological properties of regenerated and re-innervated soleus muscles of the rat
C. Davis (1991)
10.1093/JN/133.1.140
Early postnatal food intake alters myofiber maturation in pig skeletal muscle.
Louis Lefaucheur (2003)
10.1159/000016658
Sexual Dimorphism in the Rabbit Masseter Muscle: Myosin Heavy Chain Composition of Neuromuscular Compartments
A. English (1999)
10.1242/jeb.01076
Hypergravity from conception to adult stage: effects on contractile properties and skeletal muscle phenotype
C. Bozzo (2004)
10.1007/978-1-4471-3682-8_25
Skeletal Muscle and Peripheral Nerves
J. P. Barbet (1993)
10.1007/BF00318358
Presence of embryonic myosin in normal postural muscles of the adult rat
L. Wanek (2004)
10.1007/BF00121158
Differences in myosin composition between human oro-facial, masticatory and limb muscles: enzyme-, immunohisto-and biochemical studies
P. Stål (2004)
10.1523/JNEUROSCI.07-12-04176.1987
Reinnervation of muscle fiber types in the newborn rat soleus
L. C. Soileau (1987)
RESPOSTA DAS FIBRAS MUSCULARES ESQUELÉTICAS DE EQUINOS DA RAÇA PURO SANGUE ÁRABE AO TREINAMENTO DE ENDURO
A. S. Rino (2010)
10.1083/JCB.123.4.823
Type 2X-myosin heavy chain is coded by a muscle fiber type-specific and developmentally regulated gene
C. Denardi (1993)
10.1113/jphysiol.2002.024760
Alterations in Slow‐Twitch Muscle Phenotype in Transgenic Mice Overexpressing the Ca2+ Buffering Protein Parvalbumin
E. Chin (2003)
10.1007/3540528806_3
Cellular and molecular diversities of mammalian skeletal muscle fibers.
D. Pette (1990)
10.1146/ANNUREV.CELLBIO.12.1.417
The mammalian myosin heavy chain gene family.
A. Weiss (1996)
10.1016/S0385-8146(99)00028-0
Developmental changes in histochemical properties of intrinsic laryngeal muscles in rats.
K. Hangai (1999)
Equine locomotory muscles : postnatal development and the influence of exercise
E. Dingboom (2002)
Murgia Muscle Diversity and Plasticity Activity-Dependent Signaling Pathways Controlling
S. Schiaffino (2007)
10.1016/S0305-0491(98)00018-2
Selective gene expression during adaptation of muscle in response to different physiological demands.
G. Goldspink (1998)
10.1016/S0309-1740(00)00051-6
Quantification of myosin heavy chain isoform in porcine muscle using an enzyme-linked immunosorbent assay.
F. F. Depreux (2000)
10.1016/0012-1606(91)90473-G
Emergence of the mature myosin phenotype in the rat diaphragm muscle.
W. LaFramboise (1991)
10.1002/AJA.1002030104
Pattern of muscle fiber type formation in the pig
L. Lefaucheur (1995)
10.1210/en.2014-1195
Myofiber androgen receptor promotes maximal mechanical overload-induced muscle hypertrophy and fiber type transition in male mice.
A. Ferry (2014)
Cardiac atrophy due to cancer: Characterization, Mechanisms and Sex Differences
Pippa F. Cosper (2011)
Plasticity in Skeletal , Cardiac , and Smooth Muscle Invited Review : Plasticity and energetic demands of contraction in skeletal and cardiac muscle
G. Sieck (2001)
10.1152/JAPPLPHYSIOL.00353.2003
Endogenous expression and developmental changes of HSP72 in rat skeletal muscles.
T. Ogata (2003)
10.1046/j.1469-7580.1997.19040613.x
Changes in muscle fibre type, muscle mass and IGF‐I gene expression in rabbit skeletal muscle subjected to stretch
S. Yang (1997)
10.1007/BF00240928
Spatial and temporal patterns of myosin heavy chain expression in developing rat extraocular muscle
J. Brueckner (2004)
10.1002/J.2048-7940.1995.TB01654.X
Clinical nursing implications for the recovery of atrophied skeletal muscle following bed rest.
B. S. St Pierre (1995)
Developmental modulation of myosin expression by thyroid hormone in avian skeletal muscle.
M. Gardahaut (1992)
10.1016/0014-5793(91)80315-T
Biphasic expression of slow myosin light chains and slow tropomyosin isoforms during the development of the human quadriceps muscle
C. Laurent-Winter (1991)
10.1016/0304-4165(90)90181-U
Electrophoretic separation and immunological identification of type 2X myosin heavy chain in rat skeletal muscle.
W. LaFramboise (1990)
See more
Semantic Scholar Logo Some data provided by SemanticScholar