Online citations, reference lists, and bibliographies.
← Back to Search

Direct Gene Transfer Into Mouse Diaphragm

H. Davis, B. Jasmin
Published 1993 · Biology, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Direct gene transfer into skeletal muscle is a potential therapeutic strategy for inherited primary myopathies such as Duchenne muscular dystrophy (DMD). In order to affect the life‐expectancy of these patients, it will be necessary to carry out gene therapy on the diaphragm. To this end, we report efficient introduction of pure recombinant plasmid DNA into the mouse diaphragm, without causing significant damage. Application of this approach to the diaphragm of the mdx mouse will provide information on the potential usefulness of gene therapy for the treatment of DMD patients.
This paper references
10.1093/HMG/1.6.363
Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle.
J. Wolff (1992)
10.1073/PNAS.81.4.1189
X chromosome-linked muscular dystrophy (mdx) in the mouse.
G. Bulfield (1984)
10.1089/HUM.1993.4.2-151
Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression.
H. Davis (1993)
Methods for Studying Mononuclear Phagocytes (Adams
A. M. Dannenberg (1981)
10.1038/338259A0
Association of dystrophin and an integral membrane glycoprotein
K. Campbell (1989)
10.1016/0014-5793(93)80602-Q
Restoration of dystrophin‐associated proteins in skeletal muscle of mdx mice transgenic for dystrophin gene
K. Matsumura (1993)
10.1016/0092-8674(91)90035-W
Membrane organization of the dystrophin-glycoprotein complex
J. Ervasti (1991)
10.1016/0014-5793(92)81000-C
Age and sex influence expression of plasmid DNA directly injected into mouse skeletal muscle
D. Wells (1992)
10.1172/JCI115902
Widespread long-term gene transfer to mouse skeletal muscles and heart.
L. Stratford-Perricaudet (1992)
10.1093/NAR/17.6.2365
Construction of plasmids that express E. coli beta-galactosidase in mammalian cells.
G. Macgregor (1989)
10.1093/OXFORDJOURNALS.BMB.A072349
Duchenne/Becker muscular dystrophy: a short overview of the gene, the protein, and current diagnostics.
L. Kunkel (1989)
10.1089/HUM.1993.4.6-733
Plasmid DNA is superior to viral vectors for direct gene transfer into adult mouse skeletal muscle.
H. Davis (1993)
10.1038/352536A0
The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy
H. Stedman (1991)
10.1016/B978-0-12-044220-1.50047-7
HISTOCHEMICAL STAINS FOR MACROPHAGES IN CELL SMEARS AND TISSUE SECTIONS: β-GALACTOSIDASE, ACID PHOSPHATASE, NONSPECIFIC ESTERASE, SUCCINIC DEHYDROGENASE, AND CYTOCHROME OXIDASE
A. Dannenberg (1981)
10.1089/HUM.1990.1.3-241
Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector.
L. Stratford-Perricaudet (1990)
10.1073/PNAS.89.7.2581
Adenovirus as an expression vector in muscle cells in vivo.
B. Quantin (1992)
Conditions affecting direct gene transfer into rodent muscle in vivo.
J. Wolff (1991)
BioTechniques 11 , 474485 . Ill ]
B. Quantin (1991)
10.1016/0278-6915(83)90119-9
Methods for Studying Mononuclear Phagocytes
D. Adams (1981)
10.1016/0012-1606(88)90183-2
Embryonic and neonatal myosin heavy chain in denervated and paralyzed rat skeletal muscle.
S. Schiaffino (1988)
10.1126/SCIENCE.1690918
Direct gene transfer into mouse muscle in vivo.
J. Wolff (1990)
10.1093/HMG/1.1.35
Human dystrophin expression corrects the myopathic phenotype in transgenic mdx mice.
D. Wells (1992)
10.1002/j.1460-2075.1986.tb04620.x
Use of a recombinant retrovirus to study post‐implantation cell lineage in mouse embryos.
J. Sanes (1986)
10.1038/ng0493-283
The structural and functional diversity of dystrophin
A. H. Ahn (1993)
Nature Genetics 3,283-291
A. H. Ahn (1993)
10.1016/S0095-5108(18)30549-9
Duchenne and Becker muscular dystrophies: genetics, prenatal diagnosis, and future prospects.
F. Bieber (1990)
10.1016/0378-1119(86)90137-X
Powerful and versatile enhancer-promoter unit for mammalian expression vectors.
M. K. Foecking (1986)



This paper is referenced by
10.1038/sj.gt.3300553
Mini- and full-length dystrophin gene transfer induces the recovery of nitric oxide synthase at the sarcolemma of mdx4cv skeletal muscle fibers
A. Decrouy (1998)
10.1007/978-1-4419-1207-7_3
Gene Therapy for the Respiratory Muscles
G. Danialou (2010)
10.1038/sj.gt.3300407
Mini-dystrophin gene transfer in mdx4cv diaphragm muscle fibers increases sarcolemmal stability
A. Decrouy (1997)
10.1007/978-94-011-0547-7_5
Intramuscular injection of plasmid DNA.
D. Wells (1995)
10.1177/096368979900800305
Extracorporeal Circulation as a New Experimental Pathway for Myoblast Implantation in mdx Mice
Y. Torrente (1999)
10.1007/s004410000247
Gene transfer into individual muscle fibers and conditional gene expression in living animals
Andreas Sander (2000)
10.1016/S0065-2660(05)54001-X
The mechanism of naked DNA uptake and expression.
J. Wolff (2005)
10.1017/S146239940200515X
Immunological hurdles in the path to gene therapy for Duchenne muscular dystrophy.
D. Wells (2002)
10.1038/sj.gt.3301425
The role of receptors in the maturation-dependent adenoviral transduction of myofibers
Baohong Cao (2001)
10.1038/SJ.GT.3302379
Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD)
T. Athanasopoulos (2004)
10.1016/S0264-410X(00)00247-4
Recombinant plasmid expressing a truncated dengue-2 virus E protein without co-expression of prM protein induces partial protection in mice.
Raquel Ocazionez Jimenez (2000)
10.1007/978-94-011-0547-7_18
DNA-based immunization.
H. L. Davis (1995)
10.1089/HUM.1995.6.9-1129
Nonviral gene therapy: the promise of genes as pharmaceutical products.
F. Ledley (1995)
10.1006/MTHE.2002.0723
Ultrasound increases plasmid-mediated gene transfer to dystrophic muscles without collateral damage.
G. Danialou (2002)
10.1134/S1062359010050031
Muscle regeneration and the state of the thymus in adult rats under laser irradiation and alloplasty of newborn gastrocnemius muscle and diaphragm
N. Bulyakova (2010)
10.1016/0264-410X(94)90073-6
Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen.
H. Davis (1994)
10.1111/j.1749-6632.1995.tb44728.x
Use of Plasmid DNA for Direct Gene Transfer and Immunization
H. Davis (1995)
10.1165/AJRCMB.13.5.7576685
Efficiency and functional consequences of adenovirus-mediated in vivo gene transfer to normal and dystrophic (mdx) mouse diaphragm.
B. Petrof (1995)
PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version
E. Kulczykowska (2001)
10.1046/J.1365-2109.1997.T01-1-00845.X
Transient expression of two luciferase reporter gene constructs in developing embryos of Macrobrachium lanchesteri (De Man)
J. Ben-sheng (1997)
10.1016/S0169-409X(97)00112-9
Pharmacokinetic considerations in somatic gene therapy.
Shapiro Ledley T (1998)
Review article Gene therapy in Duchenne muscular dystrophy
K. Inui (1996)
10.1146/annurev.immunol.18.1.927
DNA vaccines: immunology, application, and optimization*.
S. Gurunathan (2000)
10.1007/978-1-4613-0357-2_16
DNA-Based Immunization: Prospects For a Hepatitis B Vaccine
H. Davis (1995)
10.1007/978-3-642-59955-2
On Vaccines
R. Robertson (2009)
10.1023/A:1016420102549
Pharmaceutical Approach to Somatic Gene Therapy
F. Ledley (2004)
10.1007/s10126-004-5129-z
Analysis of DNA-Vaccinated Fish Reveals Viral Antigen in Muscle, Kidney and Thymus, and Transient Histopathologic Changes
K. Garver (2004)
10.1002/(SICI)1521-2254(200003/04)2:2<76::AID-JGM97>3.0.CO;2-4
Hypothesis: naked plasmid DNA is taken up by cells in vivo by a receptor‐mediated process
V. Budker (2000)
10.1111/j.1440-169X.2009.01117.x
The feasibility of non‐viral gene transfer to the diaphragm in vivo
M. Beshay (2009)
10.1089/HUM.1993.4.2-151
Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression.
H. Davis (1993)
10.1002/jor.20781
Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin‐deficient mice
B. Wang (2009)
10.1016/0387-7604(96)00043-5
Gene therapy in Duchenne muscular dystrophy
K. Inui (1996)
See more
Semantic Scholar Logo Some data provided by SemanticScholar