Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

The Action Of Chromium On Serum Lipids And On Atherosclerosis In Cholesterol-fed Rabbits.

Abraham S. Abraham, M. Sonnenblick, M. Eini
Published 1982 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Eight rabbits, fed on a 1% cholesterol diet for 30 days, were injected daily with potassium chromate for a further 60 days. A 50% reduction in aortic intimal plaque area and in aortic total cholesterol content was observed. However, although levels of serum cholesterol and triglycerides were consistently lower and levels of high density lipoprotein fractions consistently higher in the chromium-treated as compared to the control rabbits, these differences did not reach statistical significance. A further 6 rabbits were injected with potassium chromate and fed on a 1% cholesterol diet for 12 weeks. Mean aortic cholesterol content (+/-SEM) was 40.23 mg/10 cm aortic length (+/-7.50) as compared to 66.24 mg/10 cm (+/- 7.89) in a control group (P less than 0.05), whereas the area of aortic intima covered by macroscopic plaques was 67.5% (+/-2.79) and 81.1% (+/-3.14) (P less than 0.01) respectively.
This paper references
10.1093/AJCN/33.11.2294
The effect of chromium on established atherosclerotic plaques in rabbits.
Abraham S. Abraham (1980)
10.1016/S0140-6736(76)90291-9
SERUM-HIGH-DENSITY-LIPOPROTEIN AND ATHEROSCLEROTIC HEART-DISEASE
K. Berg (1976)
10.1016/S0140-6736(76)92991-3
SERUM-H.D.L.IN ATHEROSCLEROTIC HEART-DISEASE
K. Berg (1976)
10.1016/0009-8981(67)90027-7
Electrophoresis and sudan black staining of lipoproteins on gelatinised cellulose acetate
B. Colfs (1967)
10.1016/0021-9150(81)90041-1
Elevation of serum HDL and HDL cholesterol in cholesterol in cholesterol-FED male rabbits treated with estrogen
T. I. Pynadath (1981)
10.1056/NEJM197602052940601
Serum lipoproteins and coronary heart disease in a population study of Hawaii Japanese men.
G. Rhoads (1976)
10.1016/0002-9343(51)90183-0
Protein-lipid relationships in human plasma. II. In atherosclerosis and related conditions.
D. Barr (1951)
Intestinal absorption of trace quantities of chromium.
R. Donaldson (1966)
10.1161/01.CIR.55.5.767
HDL Cholesterol and Other Lipids in Coronary Heart Disease: The Cooperative Lipoprotein Phenotyping Study
W. Castelli (1977)
10.1016/0003-2697(74)90035-9
The direct determination of serum chromium by an atomic absorption spectrophotometer with a heated graphite atomizer.
R. Pekarek (1974)
10.7326/0003-4819-90-1-85
Cholesterol in the prediction of atherosclerotic disease. New perspectives based on the Framingham study.
W. Kannel (1979)
10.1016/0002-9343(77)90874-9
High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study.
T. Gordon (1977)
10.1016/S0140-6736(77)92274-7
THE TROMSØHEART-STUDY: HIGH-DENSITY LIPOPROTEIN AND CORONARY HEART-DISEASE: A PROSPECTIVE CASE-CONTROL STUDY
N. E. Miller (1977)
10.1016/0021-9150(82)90201-5
The effect of chromium on cholesterol-induced atherosclerosis in rabbits.
Abraham S. Abraham (1982)
10.1152/AJPLEGACY.1965.209.2.433
INFLUENCE OF CHROMIUM, CADMIUM, AND LEAD ON RAT AORTIC LIPIDS AND CIRCULATING CHOLESTEROL.
H. Schroeder (1965)
10.3181/00379727-109-27358
Effect of Chromium, Cadmium and Lead on Serum Cholesterol of Rats
H. Schroeder (1962)
10.1093/JN/94.4.475
Serum cholesterol levels in rats fed thirteen trace elements.
H. Schroeder (1968)
10.1093/JN/106.10.1391
Effect of dietary chromium on glucose tolerance and serum cholesterol in guinea pigs.
A. Preston (1976)
10.1016/0021-9150(78)90151-X
Pharmacological profile of BR-931, a new hypolipidemic agent that increases high-density lipoproteins.
C. Sirtori (1978)
Review of Pediatrics
Donald A. Hillman (1981)
10.1016/S0140-6736(80)90280-9
ALPHA LIPOPROTEIN (HDL) CHOLESTEROL IN THE SERUM AND THE RISK OF CORONARY HEART DISEASE AND DEATH
A. Keys (1980)
10.1093/AJCP/27.5_TS.583
Simple rapid microtechnic for serum total cholesterol.
Bennie Zak (1957)



This paper is referenced by
10.1254/JJP.33.279
Experimental hyperlipidemia and atherosclerosis induced by cholesterol diet in SPF Japanese white rabbits.
S. Nakayama (1983)
10.17221/2010-VETMED
Chromium as an essential nutrient: a review
A. Pechová (2018)
10.1007/978-1-4684-4775-0
Biochemistry of the Essential Ultratrace Elements
E. Frieden (1984)
10.1007/s12011-018-1356-4
Effects of Selenium- and Chromium-Enriched Diets on Growth Performance, Lipid Profile, and Mineral Concentration in Different Tissues of Growing Rabbits
S. Amer (2018)
Performance of Dual Purpose Chicken Supplemented with Chromium Yeast and Nano Chromium
V. Malathi (2015)
10.1007/BF01145323
Progression and regression of coronary artery disease in one year
J. Balkin (2005)
10.1016/0026-0495(92)90318-5
The effects of chromium supplementation on serum glucose and lipids in patients with and without non-insulin-dependent diabetes.
Abraham S. Abraham (1992)
10.1016/S0306-9877(97)90219-X
Exploiting complementary therapeutic strategies for the treatment of type II diabetes and prevention of its complications.
M. Mccarty (1997)
10.1146/ANNUREV.NU.08.070188.002551
Chromium in human nutrition.
E. Offenbacher (1988)
10.1007/s12011-011-9116-8
The Effect of Different Levels of Organic and Inorganic Chromium Supplementation on Production Performance, Carcass Traits and Some Blood Parameters of Broiler Chicken Under Heat Stress Condition
M. Moeini (2011)
10.4093/JKD.2016.17.2.112
Micronutrients and Diabetes Mellitus: The Role of Chromium
Ju Hee Kang (2016)
10.1063/1.5125399
Progress in chromium research and related diseases
Yiyuan Tao (2019)
10.5897/JPHE.9000026
Chromium and copper in toenails of some Kano inhabitants
J. Ayodele (2009)
10.1016/S0306-9877(98)90065-2
Complementary measures for promoting insulin sensitivity in skeletal muscle.
M. Mccarty (1998)
10.1007/978-3-030-03742-0_5
Chromium in Health and Longevity
Ruslana Iskra (2018)
10.1016/S0306-9877(96)90243-1
Up-regulation of intracellular signalling pathways may play a central pathogenic role in hypertension, atherogenesis, insulin resistance, and cancer promotion--the 'PKC syndrome'.
M. Mccarty (1996)
10.1016/S2095-3119(14)60835-2
Effects of organic chromium supplementation to finishing lambs diet on growth performance, carcass characteristics and meat quality
L. Moreno-Camarena (2015)
10.1007/s40572-016-0117-9
Environmental Metals and Cardiovascular Disease in Adults: A Systematic Review Beyond Lead and Cadmium
Anne E Nigra (2016)
EFFECT OF SUPPLEMENTING DIFFERENT SOURCES OF CHROMIUM TO DIET ON SOME PHYSIOLOGICAL TRAITS OF BROILER CHICKENS
Luma K. Al-Bandr (2010)
10.1006/rtph.1997.1136
Chromium as an essential nutrient for humans.
R. Anderson (1997)
10.1016/0026-0495(85)90151-9
Glucose tolerance and plasma lipid distributions in rats fed a high-sucrose, high-cholesterol, low-chromium diet.
D. Donaldson (1985)
10.3923/PJN.2010.942.949
Effect of supplementing different levels of chromium yeast to diet on broiler chickens on some physiological traits.
D. Ibrahim (2010)
Effects of Dietary Chromium on Immune System
E. E. Gültepe (2017)
10.1016/0048-9697(89)90196-4
Essentiality of chromium in humans.
R. Anderson (1989)
10.1016/j.jtemb.2017.03.007
Effects of dietary chromium supplementation on muscle and bone mineral interaction in broiler chicken.
A. A. Saeed (2017)
10.1038/srep15606
Chromium exposure and incidence of metabolic syndrome among American young adults over a 23-year follow-up: the CARDIA Trace Element Study
J. Bai (2015)
Chromium, vanadium and ascorbate effects on lipids, cortisol, glucose and tissue ascorbate of guinea pigs
Wole Kola Oladut (1986)
Semantic Scholar Logo Some data provided by SemanticScholar