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Abnormalities Of Central Motor Conduction In Parkinson's Disease

R. Kandler, J. Jarratt, H. Sagar, E. J. W. Gumpert, N. Jordan
Published 1990 · Medicine

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The new technique of magnetic stimulation was used to measure amplitude of the motor evoked potential (MEP) recorded from abductor digiti minimi whilst stimulating at the head, and motor conduction time (MCT) between head and neck. Bilateral studies were made in 12 normal subjects and 56 patients with Parkinson's disease. The amplitudes of the MEPs were significantly larger (P less than 0.05) in the patients (mean 1.6 mV, SD 1.4) compared with the normal subjects (mean 0.9 mV, SE 0.6). MCTs were significantly shorter (P less than 0.001) in patients (mean 8.1 ms, SD 1.3) compared with the normal subjects (mean 9.4 ms, SD 1.2). Although the pathophysiological basis of these changes has not been determined, they provide objective measurements which may be clinically valuable in monitoring therapy.
This paper references

This paper is referenced by
Chapter 42 Topics in transcranial magnetic stimulation
M. Hallett (2000)
Magnetic brain stimulation in multiple system atrophy
G. Wenning (1997)
Impaired motor cortical inhibition in Parkinson's disease: motor unit responses to transcranial magnetic stimulation
B. U. Kleine (2001)
Chapter 27 – Motor Evoked Potentials
N. Murray (2005)
Abnormal facilitation of the response to transcranial magnetic stimulation in patients with Parkinson's disease
J. Valls-Solé (1994)
Combination of rTMS and Treadmill Training Modulates Corticomotor Inhibition and Improves Walking in Parkinson Disease
Y. Yang (2013)
Neurophysiological evaluation of motor corticospinal pathways by TMS in idiopathic early-onset Parkinson’s disease
A. Perretti (2011)
Motor Evoked Potential in Patients with Parkinson’s Disease: A Transcranial Magnetic Stimulation Study
Haneen R. Ahmed (2018)
Sensory and motor evoked potentials in multiple system atrophy: A comparative study with Parkinson's disease
G. Abbruzzese (1997)
Central motor conduction time.
K. Udupa (2013)
Project title: Effects of combined repetitive transcranial magnetic stimulation and treadmill training on gait performance in Parkinson’s disease – a randomised controlled trial
Motor cortex dysfunction revealed by cortical excitability studies in Parkinson's disease: influence of antiparkinsonian treatment and cortical stimulation
Jean-Pascal Lefaucheur (2005)
The Effect of Fatigue on the Motor Evoked Potential of the Infraspinatus
Joseph Howard Cordell (2017)
Applications of Transcranial Magnetic Stimulation in Movement Disorders
R. Cantello (2002)
Longitudinal study of central motor conduction as a predictor of functional recovery after stroke.
A. Heald (1994)
Central motor conduction time in Parkinson's disease
Y. Mochizuki (1999)
Apomorphine can increase cutaneous inhibition of motor activity in Parkinson's disease.
P. Clouston (1996)
Parkinson's disease.
J. Rothwell (2013)
Parkinson's disease rigidity
R. Cantello (1991)
Silent period measurement revives as a valuable diagnostic tool with transcranial magnetic stimulation.
B. Haug (1992)
Befunde bei verschiedenen Krankheiten
C. Fauth (1992)
Transcranial magnetic stimulation and Parkinson’s disease
R. Cantello (2002)
Shortened silent period produced by magnetic cortical stimulation in patients with Parkinson's disease
K. Nakashima (1995)
Excitability of the lower-limb area of the motor cortex in Parkinson's disease
F. Vacherot (2010)
The soleus late response elicited by transcranial magnetic stimulation reflects agonist–antagonist postural adjustment in the lower limbs
Rie Suga (2001)
Transcranial Magnetic Stimulation in Parkinson's Disease
Jaychol Choi (1999)
Corticomotor excitability in drug-naive patients with Parkinson disease.
M. Derejko (2013)
Corticospinal Tract Impairment of Patients With Parkinson’s Disease: Triple Stimulation Technique Findings
Dan Xu (2020)
Individual Differences in Resting Corticospinal Excitability Are Correlated with Reaction Time and GABA Content in Motor Cortex
I. Greenhouse (2017)
Plastische Veränderungen des motorischen Kortex nach BIG-Physiotherapie bei Patienten mit idiopathischem Parkinson-Syndrom
Florian Restle (2015)
Motorisch evozierte Potenziale
C. Hess (2005)
VETA: a Matlab toolbox for the collection and analysis of electromyography combined with transcranial magnetic stimulation
Nicko Jackson (2019)
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