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N-acetylation In Chitosan And The Rate Of Its Enzymic Hydrolysis.
S. Hirano, H. Tsuchida, N. Nagao
Published 1989 · Materials Science, Medicine
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Partially N-acetylated derivatives (degree of substitution (d.s.) 0.2, 0.4, 0.6 and 0.8 for N-acetyl) of chitosan were prepared from prawn shell chitosan, and their susceptibility towards a lysozyme from hen egg-white, three microbial chitinases and a chitinase from potato skins was examined. The partially N-acetylated derivatives (d.s. 0.4-0.8 for N-acetyl) were 1.5-4.0 times more digestible than N-acetylchitosan (d.s. 1.0 for N-acetyl), and their enzymic hydrolysis rate is controlled by the d.s. for N-acetyl group. These data suggest that chitosan is usable as a digestible material in the biomedical and biotechnological fields.
This paper references
Lysozyme degradation of partially deacetylated chitin, its films and hydrogels.
S. Pangburn (1982)
A modified colorimetric method for the estimation of N-acetylamino sugars.
J. L. Reissig (1955)
Purification and mode of action of a chitosanase from Penicillium islandicum
D. Fenton (1981)
Chitosanase, a novel enzyme.
R. Monaghan (1973)
The Determination of Hexosamines According to Elson and Morgan.
G. Blix (1948)
Preparation of d-Glucosamine Oligosaccharides by the Enzymatic Hydrolysis of Chitosan
M. Izume (1987)
A Simple Activity Measurement of Lysozyme
T. Imoto (1971)
Heterogeneous Distribution of Amino Groups in Partially N-Acetylated Derivatives of Chitosan
S. Hirano (1981)
The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.
S. Hirano (1980)
Selective N-acylation of chitosan.
S. Hirano (1976)
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