Online citations, reference lists, and bibliographies.
← Back to Search

Tolerance Of Normal Tissue To Therapeutic Irradiation.

B. Emami, J. Lyman, A. Brown, L. Coia, M. Goitein, J. Munzenrider, B. Shank, L. Solin, M. Wesson
Published 1991 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
The importance of knowledge on tolerance of normal tissue organs to irradiation by radiation oncologists cannot be overemphasized. Unfortunately, current knowledge is less than adequate. With the increasing use of 3-D treatment planning and dose delivery, this issue, particularly volumetric information, will become even more critical. As a part of the NCI contract N01 CM-47316, a task force, chaired by the primary author, was formed and an extensive literature search was carried out to address this issue. In this issue. In this manuscript we present the updated information on tolerance of normal tissues of concern in the protocols of this contract, based on available data, with a special emphasis on partial volume effects. Due to a lack of precise and comprehensive data base, opinions and experience of the clinicians from four universities involved in the contract have also been contributory. Obviously, this is not and cannot be a comprehensive work, which is beyond the scope of this contract.
This paper references
10.2214/AJR.130.5.877
Thoracic effects of therapeutic irradiation for breast carcinoma.
J. Meyer (1978)
10.1016/S0009-9260(69)80043-7
Dose, time and fractionation: a clinical hypothesis.
F. Ellis (1969)
10.1016/0002-9610(86)90086-3
Surgical treatment of radiation injuries of the colon and rectum.
S. Jao (1986)
10.7326/0003-4819-94-3-338
The late appearance of chronic pericardial disease in patients treated by radiotherapy for Hodgkin's disease.
M. M. Applefeld (1981)
Development of radiation pneumonitis. Time and dose factors.
F. L. Jennnings (1962)
10.2214/AJR.96.1.28
Analysis of complications following megavoltage therapy for squamous cell carcinomas of the tonsillar area.
B. Grant (1966)
10.2214/AJR.108.2.293
Complications in 831 patients with squamous cell carcinoma of the intact uterine cervix treated with 3,000 rads or more whole pelvis irradiation.
M. F. Strockbine (1970)
Drug-induced heart disease
M. Bristow (1980)
10.1016/0360-3016(81)90443-0
Cerebral radionecrosis: incidence and risk in relation to dose, time, fractionation and volume.
J. E. Marks (1981)
10.1148/88.2.326
Hypothyroidism after external irradiation to the thyroid region.
J. Einhorn (1967)
Radiation oncology: rationale, technique, results
W. Moss (1973)
10.1016/0360-3016(79)91215-X
Endocrine factors influencing radiation injury to central nervous tissue.
S. Aristizabal (1979)
10.1002/1097-0142(197805)41:5<1746::AID-CNCR2820410515>3.0.CO;2-C
Remineralization of enamel by a saliva substitute designed for use by irradiated patients
I. Shannon (1978)
10.1017/S0317167100025087
Lumbo-sacral radiculopathy induced by radiation.
E. M. Ashenhurst (1977)
Mural thrombosis of the heart induced by radiation.
J. M. Brown (1973)
10.1016/0360-3016(86)90412-8
Dose volume histogram analysis of liver radiation tolerance.
M. Austin-Seymour (1986)
10.1259/0007-1285-21-249-464
Radiation myelitis of the cervical spinal cord.
G. Boden (1948)
10.3109/02841867509132663
Radiation-induced lesions of the brachial plexus correlated to the dose-time-fraction schedule.
H. Svensson (1975)
10.1259/0007-1285-36-423-163
Fractionation and dose-rate. II. Dose-time relationships in radiotherapy and the validity of cell survival curve models.
J. Fowler (1963)
10.1001/ARCHNEUR.1981.00510120087024
Radiation Damage to the Nervous System
H. Tewfik (1981)
10.1001/ARCHOTOL.1968.00770010158008
Radiation effects on the inner ear.
J. Gamble (1968)
10.1001/JAMA.1974.03230380028017
Radiation-induced coronary artery disease.
G. P. Tracy (1974)
10.1148/81.5.881
A SPATIAL MODEL OF TIME-DOSE-AREA RELATIONSHIPS IN RADIATION THERAPY.
C. F. V. Essen (1963)
10.1159/000413234
State of the art of high energy photon treatment planning.
J. Purdy (1987)
10.1017/S0022215100064495
Irradiation of the ear.
W. Leach (1965)
10.1148/75.1.50
Some factors altering the severity of acute radiation pneumonitis: variation with cortisone, heparin, and antibiotics.
W. Moss (1960)
10.1148/93.2.289
Effects of thoracic irradiation on pulmonary arterial perfusion in man.
S. Goldman (1969)
10.1148/112.3.685
Osteoradionecrosis of the mandible resulting from external megavoltage radiation therapy.
V. S. Cheng (1974)
10.1016/0360-3016(87)90041-1
A quantified approach to the analysis and prevention of urinary complications in radiotherapeutic treatment of cancer of the cervix.
H. Pourquier (1987)
10.1148/121.2.461
Hepatic radiation tolerance in Hodgkin's disease patients.
H. Poussin-Rosillo (1976)
10.1002/LARY.5540900313
Radiotherapy of early glottic cancer
A. Harwood (1980)
10.1152/JAPPL.1961.16.2.331
Effects of irradiation of chest on pulmonary function in man.
C. Emirgil (1961)
10.1001/ARCHINTE.1975.00330060087012
Thyroid Function After Radiation and Surgery for Head and Neck Cancer
R. Shafer (1975)
10.1016/0360-3016(88)90426-9
Definitive irradiation for early stage breast cancer: The University of Pennsylvania experience.
L. Solin (1988)
10.1002/1097-0142(197309)32:3<547::AID-CNCR2820320306>3.0.CO;2-4
Radiation pneumonitis: A new approach to the derivation of time‐dose factors
W. Wara (1973)
10.1002/1097-0142(197410)34:4<1278::AID-CNCR2820340440>3.0.CO;2-F
Areas of failure found at reoperation (second or symptomatic look) following “curative surgery” for adenocarcinoma of the rectum: Clinicopathologic correlation and implications for adjuvant therapy
L. Gunderson (1974)
Optic chiasmal radionecrosis.
Hammer Hm (1983)
10.1159/000173586
Postpericardiectomy syndrome in a patient with radiation-induced pericardial effusion.
E. Ferrannini (1983)
10.1159/000392813
Radiation-Induced Heart Disease1
J. Stewart (1972)
10.1016/0033-0620(84)90003-3
Radiation-induced heart disease: an update.
J. Stewart (1984)
10.1001/JAMA.1962.03050370026006
Ionizing radiation and the ear.
S. Borsanyi (1962)
10.1148/117.1.149
Bladder cancer: results of radiation therapy in 384 patients.
D. Goffinet (1975)
10.3109/02841868009130164
Dose effect relationships in cervical and thoracic radiation myelopathies.
B. Holdorff (1980)
10.1016/0360-3016(83)90420-0
Surfactant release as an early measure of radiation pneumonitis.
P. Rubin (1983)
10.1097/00004728-197904000-00017
Radiation Necrosis of the Brain: Correlation Between Patterns on Computed Tomography and Dose of Radiation
M. Mikhael (1979)
10.2214/AJR.131.1.63
Value of computed tomography in radiotherapy of lung cancer.
B. Emami (1978)
10.1016/S0039-6109(16)42585-5
Defining the needs for adjuvant therapy of rectal and colonic cancer.
W. Enker (1981)
Clinical spectrum of radiation induced pericarditis.
G. Ca (1983)
10.1016/0360-3016(84)90202-5
Unilateral radiation nephropathy--the long-term significance.
T. Kim (1984)
10.1016/0360-3016(78)90144-X
Radiation myelopathy of the cervical spinal cord: time, dose and volume factors.
J. Abbatucci (1978)
10.1016/0360-3016(86)90279-8
A prospective study of treatment techniques to minimize the volume of pelvic small bowel with reduction of acute and late effects associated with pelvic irradiation.
M. Gallagher (1986)
10.2214/AJR.108.1.27
Dose, time, volume relationships in squamous cell carcinoma of the supraglottic larynx.
L. Shukovsky (1970)
The effect of radiation on normal tissues in management of head and neck cancer
F. Parsons (1984)
Biophysical models in radiation oncology
Kristian R. Albert (1984)
10.1148/74.1.104
Time-dose relationship of radiation; fibrosis of lung.
J. Evans (1960)
10.1148/119.3.665
Osteonecrosis in patients treated with definitive radiotherapy for squamous cell carcinomas of the oral cavity and naso-and oropharynx.
J. Bedwinek (1976)
10.1016/0360-3016(81)90032-8
Idiopathic interstitial pneumonia following bone marrow transplantation: the relationship with total body irradiation.
T. Keane (1981)
10.1016/0360-3016(86)90069-6
The predictive value of skin telangiectasia for late radiation effects in different normal tissues.
I. Turesson (1986)
10.2214/AJR.136.1.123
Contribution of CT to quantitative radiation therapy planning.
S. Prasad (1981)
48 Reports of Radiotherapy and Oncology cardiac mortality following radiation therapy for Hodgkin ’ s disease : analysis with the relative seriality model
Cassady
10.1016/0360-3016(84)90263-3
Treatment-related morbidity in phase III RTOG studies of extended-field irradiation for carcinoma of the prostate.
M. Pilepich (1984)
10.1148/23.1.153
Radiation myelitis of the dorsolumbar spinal cord.
J. Maier (1969)
10.1148/132.2.479
Factors predisposing to radiation-related small-bowel damage.
R. A. Potish (1979)
10.1016/0360-3016(81)90115-2
Brain tolerance unit: a method to estimate risk of radiation brain injury for various dose schedules.
R. Pezner (1981)
10.1016/0037-198X(74)90009-1
Complications of radiation therapy: the alimentary tract.
B. Roswit (1974)
10.1016/0360-3016(81)90152-8
The effects of radiation of parotid salivary function.
J. E. Marks (1981)
10.1016/S0161-6420(82)34612-6
Radiation optic neuropathy.
G. Brown (1982)
10.1016/0002-9343(81)90168-6
Pericardial disease in patients with cancer. The differentiation of malignant from idiopathic and radiation-induced pericarditis.
M. Posner (1981)
10.1002/1097-0142(19840715)54:2<235::AID-CNCR2820540210>3.0.CO;2-H
Radiation therapy alone in the treatment of carcinoma of the uterine cervix. II. Analysis of complications
C. Perez (1984)
10.7326/0003-4819-80-5-593
Latent radiation injury of lungs or heart activated by steroid withdrawal.
R. Castellino (1974)
10.1002/1097-0142(197605)37:5<2414::AID-CNCR2820370533>3.0.CO;2-J
Enhanced pulmonary toxicity with bleomycin and radiotherapy in oat cell lung cancer
L. Einhorn (1976)
10.1259/0007-1285-47-554-157
Letter: The late vascular effects of radiation.
J. Hopewell (1974)
Radiation-induced heart disease. Clinical and experimental aspects.
J. Stewart (1971)
10.2214/AJR.129.1.127
Severe radiation injuries of the lung.
B. Roswit (1977)
10.1016/S0368-2242(50)80056-8
Radiation myelitis of the brain-stem
G. Boden (1950)
10.1148/112.1.187
Local control and site of failure in radically irradiated supraglottic laryngeal cancer.
N. Ghossein (1974)
10.1016/0002-9149(75)90004-1
Radiation-related pericarditis.
R. Martin (1975)
10.3109/02841868309135967
Electrocardiographic changes after radiation therapy for carcinoma of the breast. Incidence and functional significance.
J. Lindahl (1983)
10.1148/122.2.389
Physiological and radiographic assessment during the development of pulmonary radiation fibrosis.
F. Prato (1977)
10.1016/0167-8140(90)90057-4
Radiation-induced brachial plexus injury: follow-up of two different fractionation schedules.
S. Powell (1990)
10.1016/0360-3016(86)90284-1
Renal complications secondary to radiation treatment of upper abdominal malignancies.
C. Willett (1986)
10.1016/0360-3016(84)90203-7
Symptomatic radiation-induced pericarditis in Hodgkin's disease.
W. Mill (1984)
10.1016/0360-3016(81)90131-0
Radiation pneumonitis following large single dose irradiation: a re-evaluation based on absolute dose to lung.
J. Van Dyk (1981)
10.5555/URI:PII:0093775480900093
Complications of radiation treatment of Hodgkin's disease.
T. L. Thar (1980)
10.2214/AJR.105.3.659
Radiation tolerance of the thoracic spinal cord.
T. Phillips (1969)
10.1001/jama.1968.03150100059015
Morphology of radiation-induced heart disease.
L. Fajardo (1968)
10.2307/3574407
The effect of multiple small doses of x rays on skin reactions in the mouse and a basic interpretation.
B. Douglas (1976)
10.1159/000392812
Radiation Pathology and the Clinical Response of Lung and Esophagus1
T. L. Phillips (1972)
10.1259/0007-1285-36-423-153
I. The Dose-time Relationship in Radiotherapy and the Validity of Cell Survival Curve Models
F. Ellis (1963)
10.1017/S0022215100065233
Effects on the hearing of patients treated by irradiation in the head and neck area.
A. Dias (1966)
10.1097/00004424-197705000-00004
Regional and total lung function in patients following pulmonary irradiation.
F. Prato (1977)
10.1016/0360-3016(82)90517-X
Changes in early and late radiation responses with altered dose fractionation: implications for dose-survival relationships.
H. Thames (1982)
10.1016/0360-3016(84)90184-6
The latent period in clinical radiation myelopathy.
T. Schultheiss (1984)
10.1159/000392805
CLINICAL RADIATION TOLERANCE OF THE SKIN AND UPPER AERODIGESTIVE TRACT.
C. F. V. Essen (1972)
10.1148/108.2.397
The pulmonary effect of mantle irradiation in patients with Hodgkin's disease.
J. Lokich (1973)
10.1016/0360-3016(77)90157-2
Radiation related toxicities in National Wilms' Tumor Study Number 1.
M. Tefft (1977)
10.2307/3572601
Clinical Radiation Pathology
P. Rubin (1968)
10.1016/0360-3016(83)90225-0
The effects of irradiation on the eye and optic nerve.
J. T. Parsons (1983)
10.1002/1097-0142(197910)44:4<1256::AID-CNCR2820440415>3.0.CO;2-T
The morphologic effects of radiation administered therapeutically for intracranial gliomas.A Postmortem study of 25 cases
P. Burger (1979)
10.1016/0037-198X(74)90008-X
Complications of radiation therapy: the thorax.
H. Libshitz (1974)
10.1016/0360-3016(82)90179-1
Irradiation of mouse lungs causes a dose-dependent increase in lung weight.
J. Sharplin (1982)
10.1016/S0140-6736(64)92010-0
CHRONIC BRONCHITIS AND RADIOTHERAPY OF THE LUNG.
P. Gillam (1964)
10.1001/ARCHINTE.1973.00320090059006
Acute and late reactions to irradiation in the treatment of Hodgkin's disease.
A. Glicksman (1973)
Tolerance of normal tissue to therapeutic irradiation
B Emami (1991)
10.1016/0360-3016(78)90002-0
Radiation pneumonitis: experience following a large single dose of radiation.
C. Fryer (1978)
10.1002/1097-0142(197805)41:5<1751::AID-CNCR2820410516>3.0.CO;2-N
Radiation myelopathy of the thoracic spinal cord in long term survivors treated with radical radiotherapy using conventional fractionation
P. M. Lambert (1978)
Complications of intensive megavoltage radiotherapy for Hodgkin's disease.
H. Kaplan (1973)
10.1002/1097-0142(19810415)47:8<1980::AID-CNCR2820470813>3.0.CO;2-Y
Osteonecrosis in patients irradiated for head and neck carcinoma
R. Morrish (1981)
10.1118/1.595312
Models in radiotherapy: volume effects.
T. Schultheiss (1983)
Some observations concerning pericardial effusions and their relationship to the venous and lymphatic circulation of the heart.
A. Miller (1970)
10.1016/0360-3016(84)90163-9
Cataracts after total body irradiation and marrow transplantation: a sparing effect of dose fractionation.
H. Deeg (1984)
Magnetic Resonance Imaging of Radiation Injury to the Brain
J. Curnes (1986)
10.1001/ARCHSURG.1983.01390080013004
Surgical management of small-bowel radiation enteritis.
K. Lillemoe (1983)
10.1016/0360-3016(80)90107-8
Computed axial tomography (CAT) contribution for dosimetry and treatment evaluation in lung cancer
P. V. Houtte (1980)
10.1001/ARCHOTOL.1973.00780020117011
Radiation necrosis of the larynx. Etiology and management.
P. Stell (1973)
10.1002/1097-0142(197707)40:1<170::AID-CNCR2820400128>3.0.CO;2-9
Use of body scanner in radiotherapy treatment planning
J. Munzenrider (1977)
10.1002/1097-0142(19830501)51:9<1599::AID-CNCR2820510908>3.0.CO;2-O
Protons or megavoltage X‐rays as boost therapy for patients irradiated for localized prostatic carcinoma an early phase I/II comparison
J. Duttenhaver (1983)
10.1002/1097-0142(197602)37:2+<1186::AID-CNCR2820370830>3.0.CO;2-V
Quantification of combined radiation therapy and chemotherapy effects on critical normal tissues
T. Phillips (1976)
10.1002/1097-0142(197307)32:1<206::AID-CNCR2820320131>3.0.CO;2-9
Radiographic appearance of the chest following extended field radiation therapy for Hodgkin's disease. A consideration of time‐dose relationships
H. Libshitz (1973)
10.1016/0360-3016(83)90105-0
Iso-effect tables for tolerance of irradiated normal human tissues.
L. Cohen (1983)
10.3109/02841867309131095
Radiation induced pericarditis in Hodgkin's disease.
R. Marks (1973)
10.1378/CHEST.59.3.271
Radiographic visualization of lymphatic drainage of heart muscle and pericardial sac in the dog.
A. Miller (1971)
10.1164/ARRD.1964.89.2.264
RADIATION PNEUMONITIS. CASE REPORT OF BILATERAL REACTION AFTER UNILATERNAL IRRADIATION.
J. C. Smith (1964)
10.1016/0360-3016(80)90429-0
Dissociation of early and late damage in mouse lung
E. Travis (1980)
10.1001/jama.1968.03150040021004
Physiologic changes before and after radiation treatment for carcinoma of the lung.
P. Germon (1968)
10.1016/0360-3016(83)90361-9
Radiobiological considerations in magna-field irradiation.
R. Evans (1983)
10.1016/0360-3016(80)90316-8
Supradiaphragmatic Hodgkin's disease: significance of large mediastinal masses.
L. Prosnitz (1980)
10.1002/1097-0142(197602)37:2+<1152::AID-CNCR2820370826>3.0.CO;2-T
Long‐term effects of external radiation on the pituitary and thyroid glands
Z. Fuks (1976)
10.1016/S0140-6736(85)92089-6
SEVERE CONSTRICTIVE PERICARDITIS AFTER SINGLE 16 MeV ANTERIOR MANTLE IRRADIATION FOR HODGKIN'S DISEASE
R. Coltart (1985)
10.1016/0360-3016(81)90017-1
An iso-effect table for radiation tolerance of the human spinal cord.
L. Cohen (1981)
10.1002/1097-0142(197506)35:6<1558::AID-CNCR2820350613>3.0.CO;2-7
Radiation tolerance of the spinal cord
W. Wara (1975)
10.1016/0360-3016(81)90140-1
Some factors influencing salivary function when treating with radiotherapy.
J. Mira (1981)
10.1002/1097-0142(197308)32:2<328::AID-CNCR2820320208>3.0.CO;2-A
Lung function after mantle field irradiation in Hodgkin's disease
H. Host (1973)
10.7326/0003-4819-96-2-264_1
Principles of Cancer Treatment
S. Carter (1981)
10.1288/00005537-198411000-00034
Management of Head and Neck Cancer: A Multidisciplinary Approach
R. Million (1984)
10.1016/0360-3016(79)90068-3
The response of pig skin to single and fractionated high dose-rate and continuous low dose-rate 137Cs-irradiation-I: Experimental design and results.
I. Turesson (1979)
10.1002/1097-0142(19830315)51:6<980::AID-CNCR2820510603>3.0.CO;2-Y
Ocular and orbital complications following radiation therapy of paranasal sinus malignancies and review of literature
N. Nakissa (1983)
10.1002/1097-0142(197606)37:6<2605::AID-CNCR2820370607>3.0.CO;2-W
Carcinoma of the nasopharynx. Eighteen years' experience with megavoltage radiation therapy
R. Hoppe (1976)
10.1056/NEJM198303103081005
Late cardiac effects of therapeutic mediastinal irradiation. Assessment by echocardiography and radionuclide angiography.
J. Gottdiener (1983)
10.1148/104.3.629
Retinal and optic nerve complications in a high dose irradiation technique of ethmoid sinus and nasal cavity.
L. Shukovsky (1972)
10.7326/0003-4819-86-1-81
Pulmonary effects of radiation therapy.
N. Gross (1977)
10.1016/S0009-9260(76)80107-9
Acute transient radiation hepatitis following whole abdominal irradiation.
T. Kim (1976)
10.1016/0360-3016(77)90190-0
Early radiation dose-response in lung: an ultrastructural study.
H. Moosavi (1977)
10.1016/S0039-6109(16)42931-2
The surgical management of the radiation-injured intestine.
G. Marks (1983)
10.1016/0360-3016(80)90380-6
Radiation necrosis of the mandible: a 10 year study. Part I. Factors influencing the onset of necrosis.
C. G. Murray (1980)
10.1016/0360-3016(82)90462-X
How important is breathing in radiation therapy of the thorax?
R. Henkelman (1982)
10.2307/3575550
Repair in mouse lung after split doses of X rays.
E. Travis (1981)
10.1159/000392794
A Direction for Clinical Radiation Pathology
P. Rubin (1972)
10.5555/URI:PII:0093775476900439
The role of megavoltage radiation therapy in the treatment of prostatic carcinoma.
D. A. Pistenma (1976)
10.1148/99.2.403
Dose response in human and experimental radiation-induced heart disease. Application of the nominal standard dose (NSD) concept.
J. Stewart (1971)
10.1016/0360-3016(79)90951-9
Adriamycin cardiotoxicity in stage IV breast cancer: possible enhancement with prior left chest radiation therapy.
T. Kinsella (1979)
10.2307/3575726
Radiation response of the canine cardiovascular system.
P. Gavin (1982)
10.1002/1097-0142(197702)39:2+<973::AID-CNCR2820390737>3.0.CO;2-O
Bladder cancer. Superiority of preoperative irradiation and cystectomy in clinical stages B2 and C
L. S. Miller (1977)
10.1016/0360-3016(86)90413-X
Dose dependence of complication rates in cervix cancer radiotherapy.
C. Orton (1986)
10.7326/0003-4819-101-3-417_2
Conservative management of breast cancer: New surgical and radiotherapeutic techniques
J. Harris (1983)
10.1016/0002-9149(85)90409-6
Early cardiac changes related to radiation therapy.
M. Ikäheimo (1985)
10.1016/0360-3016(83)90262-6
Liver complications in lymphomas treated with a combination of chemotherapy and radiotherapy: preliminary results.
E. Haddad (1983)
10.1148/82.6.1055
SEQUELAE OF RADICAL RADIOTHERAPY OF CARCINOMA OF THE LUNG.
S. Hellman (1964)
10.1016/0360-3016(86)90358-5
Oral side effects of head and neck irradiation: correlation between clinical manifestations and laboratory data.
A. Kuten (1986)
10.1148/130.2.473
Assessment of renal function following irradiation of the intact spleen for Hodgkin disease.
B. Birkhead (1979)
10.1016/0002-9610(72)90077-3
Carcinoma of the nasopharynx. Review of 146 patients with emphasis on radiation dose and time factors.
H. Mönch (1972)
10.1016/0360-3016(82)90166-3
Long-term effects of radiotherapy on taste and salivary function in man.
K. Mossman (1982)
10.3109/02841856609139546
Time-dose considerations in radiation myelopathy.
H. L. Atkins (1966)
10.1097/00004728-198609000-00004
Assessment of acute radiation-induced pulmonary changes using computed tomography.
K. Mah (1986)
10.1016/0360-3016(80)90175-3
Therapeutic irradiation and brain injury.
G. Sheline (1980)
10.1016/0360-3016(80)90381-8
Radiation necrosis of the mandible: a 10 year study. Part II. Dental factors; onset, duration and management of necrosis.
C. G. Murray (1980)
10.1016/B978-0-08-092557-8.50004-5
FROM THE PREFACE TO THE FIRST EDITION
S. R. Sandler (1986)
10.1002/1097-0142(197503)35:3<795::AID-CNCR2820350335>3.0.CO;2-M
Dose and treatment factors in radiation related pericardial effusion associated with the mantle technique for Hodgkin's disease
R. Byhardt (1975)
10.1097/00005792-197505000-00005
RADIATION-RELATED PERICARDIAL EFFUSIONS IN PATIENTS WITH HODGKIN'S DISEASE
J. Ruckdeschel (1975)
10.1288/00005537-197604000-00018
Sensori‐Neural hearing loss following radiotherapy to the nasopharynx
J. Moretti (1976)
10.1097/00000658-198112000-00010
Radiation Injury of the Rectum: Evaluation of Surgical Treatment
P. Anseline (1981)
10.1002/1097-0142(19820215)49:4<655::AID-CNCR2820490409>3.0.CO;2-I
The significance of laryngeal edema following radiotherapy of carcinoma of the vocal cord
K. Fu (1982)
Experimental radiation-induced heart disease. I. Light microscopic studies.
L. Fajardo (1970)
10.1148/89.2.302
RADIATION-INDUCED HEART DISEASE. A STUDY OF TWENTY-FIVE PATIENTS.
J. Stewart (1967)
10.1259/0007-1285-25-292-190
The limit of renal tolerance to x-rays; an investigation into renal damage occurring following the treatment of tumours of the testis by abdominal baths.
P. B. Kunkler (1952)
10.1016/0360-3016(85)90178-6
Excisional biopsy, axillary node dissection and definitive radiotherapy for Stages I and II breast cancer.
B. Danoff (1985)
10.1259/0007-1285-54-645-787
Tolerance of the mature human central nervous system to photon irradiation.
D. Wigg (1981)
10.1016/S0161-6420(85)33898-8
Radiation optic neuropathy.
L. Kline (1985)
10.1136/thx.20.4.303
Effect of Chronic Bronchitis on Changes in Pulmonary Function Caused by Irradiation of the Lungs
B. Hoffbrand (1965)
10.1016/0360-3016(79)90809-5
Radiotherapy of early glottic cancer--II.
A. Harwood (1979)
Response of radiation pneumonitis to adrenocorticoids.
P. Rubin (1958)
10.1016/0360-3016(76)90147-4
Radiation myelopathy of the thoracic spinal cord.
H. Reinhold (1976)
10.1016/0002-9343(81)90574-X
Radiation heart disease. Analysis of 16 young (aged 15 to 33 years) necropsy patients who received over 3,500 rads to the heart.
F. Brosius (1981)
Pathology of radiation injury
L. Fajardo (1982)
10.1002/1097-0142(196905)23:5<1001::AID-CNCR2820230505>3.0.CO;2-E
Bilateral radiation pneumonitis, a complication of the radiotherapy of bronchogenic carcinoma (report and analysis of seven cases with autopsy)
D. Bennett (1969)
Radiation injury of bone : bone injuries following radiation therapy of tumors
K. Shimanovskaya (1983)
10.1002/1097-0142(197606)37:6<2813::AID-CNCR2820370637>3.0.CO;2-S
Mantle irradiation in Hodgkin's disease. An analysis of technique, tumor eradication, and complications
R. Carmel (1976)
10.2214/AJR.117.3.553
Carcinoma of the larynx. Results of radiation therapy in 213 patients.
D. Goffinet (1973)
10.1097/00005792-196705000-00003
HEART DISEASE FOLLOWING RADIATION
K. Cohn (1967)



This paper is referenced by
10.1007/s11884-019-00565-0
Consequences of Pelvic Radiotherapy on Urinary Function in Women
Ly N. Hoang (2019)
10.1017/S1460396918000547
A review of radiation genomics: integrating patient radiation response with genomics for personalised and targeted radiation therapy
Lu Xu (2019)
10.1016/j.brachy.2008.07.007
Late chest wall toxicity after MammoSite breast brachytherapy.
J. Brashears (2009)
10.1017/S1460396919000499
Impact of brachial plexus movement during radical radiotherapy for head and neck cancers: the case for a larger planning organ at risk volume margin
A. Sarwar (2020)
10.3389/fonc.2020.00568
Single-Isocenter Volumetric Modulated Arc Therapy vs. CyberKnife M6 for the Stereotactic Radiosurgery of Multiple Brain Metastases
Rami A. El Shafie (2020)
10.18869/ACADPUB.IJRR.18.1.117
Estimation of the visual system complication probability on children with Medulloblastoma after Craniospinal irradiation with three-dimensional conformal radiotherapy
P. Shoa (2020)
10.1016/S1278-3218(97)82943-5
Mécanismes biologiques des effets tardifs des radiations ionisantes
E. Lartigau (1997)
10.1016/0360-3016(94)90207-0
Estimation of normal tissue complication probabilities with three-dimensional technology.
L. Marks (1994)
10.1016/0167-8140(93)90264-9
Probability of radiation-induced complications in normal tissues with parallel architecture under conditions of uniform whole or partial organ irradiation.
E. Yorke (1993)
10.1016/0360-3016(93)90398-F
Use of Veff and iso-NTCP in the implementation of dose escalation protocols.
R. Ten Haken (1993)
10.1016/0360-3016(94)00471-4
Analysis of clinical complication data for radiation hepatitis using a parallel architecture model.
A. Jackson (1995)
10.1016/1053-4296(92)90025-G
Three-Dimensional Conformal Radiation Therapy at the Memorial Sloan-Kettering Cancer Center.
Leibel (1992)
10.1118/1.1288393
Red marrow dosimetry for radiolabeled antibodies that bind to marrow, bone, or blood components.
G. Sgouros (2000)
Radiation Therapy for Benign Disease
T. Eng (2019)
10.1016/0924-4212(96)80033-8
Aspects physiopathologiques de la fibrose radio-induite
S. Delanian (1995)
10.3109/02841869709109220
Specification of the dose to organs at risk in external beam radiotherapy.
E. Dale (1997)
10.1259/BJR.70.833.9227235
Predicting late rectal complications following prostate conformal radiotherapy using biologically effective doses and normalized dose-surface histograms.
R. Mackay (1997)
10.1111/j.1754-9485.2010.02164.x
Rectal dose reduction with IMRT for prostate radiotherapy
N. Hardcastle (2010)
10.1002/hed.25997
Analysis of skin dose distribution for the prediction of severe radiation dermatitis in head and neck squamous cell carcinoma patients treated with concurrent chemo‐radiotherapy
P. Bonomo (2019)
10.1046/j.1464-410x.2001.02145.x
Radical radiation therapy options for organ‐confined prostate cancer
P. Plowman (2001)
10.1016/S0167-8140(98)00057-7
Regional dose response to pulmonary irradiation using a manual method.
B. Levinson (1998)
10.1093/JJCO/29.3.164
Radiation-induced esophageal carcinoma 30 years after mediastinal irradiation: case report and review of the literature.
O. Micke (1999)
10.1016/S1278-3218(00)87980-9
La radiothérapie conformationnelle du cancer bronchique non à petites cellules
F. Mornex (1999)
Die Beeinflussung von Nebenwirkungen der Strahlentherapie des Beckens durch hydrolytische Enzyme. Eine randomisierte Doppelblindstudie.
N. Zamboglou (2000)
10.1002/(SICI)1097-0347(200005)22:3<303::AID-HED15>3.0.CO;2-U
Surgical treatment of recalcitrant radiation‐induced gastric erosions
Y. Yeung (2000)
10.1053/SRAO.2000.9424
The physical parameters and molecular events associated with radiation-induced lung toxicity.
Z. Vujasković (2000)
10.1016/S0167-8140(01)00281-X
Rectal sequelae after conformal radiotherapy of prostate cancer: dose-volume histograms as predictive factors.
S. Wachter (2001)
10.1054/BRST.2000.0259
Successful treatment of radiation induced breast ulcer with hyperbaric oxygen.
M. Borg (2001)
10.1053/SRAO.2001.23481
Partial irradiation of the rectum.
A. Jackson (2001)
10.1007/S11864-002-0044-X
Inoperable localized stage I and stage II non-small-cell lung cancer
E. Gressen (2002)
10.1053/SNUC/2002.31025
Phase I study of peptide receptor radionuclide therapy with [In-DTPA]octreotide: the Rotterdam experience.
R. Valkema (2002)
10.1016/S0377-2217(02)00078-4
Optimal adaptive control of treatment planning in radiation therapy
G. Arcangeli (2002)
See more
Semantic Scholar Logo Some data provided by SemanticScholar