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Lipid Bilayers: Thermodynamics, Structure, Fluctuations, And Interactions.

S. Tristram-Nagle, J. Nagle
Published 2004 · Chemistry, Medicine

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This article, adapted from our acceptance speech of the Avanti Award in Lipids at the 47th Biophysical Society meeting in San Antonio, 2003, summarizes over 30 years of research in the area of lipid bilayers. Beginning with a theoretical model of the phase transition (J.F.N.), we have proceeded experimentally using dilatometry and density centrifugation to study volume, differential scanning calorimetry to study heat capacity, and X-ray scattering techniques to study structure of lipid bilayers as a function of temperature. Electron density profiles of the gel and ripple phases have been obtained as well as profiles from several fluid phase lipids, which lead to many structural results that compliment molecular dynamics simulations from other groups. Using the theory of liquid crystallography plus oriented lipid samples, we are the first group to obtain both material parameters (KC and B) associated with the fluctuations in fluid phase lipids. This allows us to use fully hydrated lipid samples, as in vivo, to obtain the structure.
This paper references
10.1103/PHYSREVE.57.7014
Interbilayer interactions from high-resolution x-ray scattering
H. Petrache (1998)
10.1016/S0006-3495(89)82807-3
Structure of the fully hydrated gel phase of dipalmitoylphosphatidylcholine.
M. Wiener (1989)
10.1016/0003-2697(78)90509-2
A differontial dilatometer
D. Wilkinson (1978)
10.1016/S0006-3495(96)79576-0
Small-angle x-ray scattering from lipid bilayers is well described by modified Caillé theory but not by paracrystalline theory.
R. Zhang (1996)
10.1103/PHYSREVLETT.81.2610
Simulations of Interacting Membranes in the Soft Confinement Regime.
Nikolai Gouliaev (1998)
Prog. Colloid Polym. Sci
L Perera (1997)
10.1103/PHYSREVE.50.5047
Theory of the structure factor of lipid bilayers.
Zhang (1994)
Order and disorder in fully hydrated unoriented bilayers of gel phase DPPC
W.-J Sun (1994)
X-ray structure determination of L ␣ phase DPPC bilayers
J F Nagle (1996)
L B ′ → L C ′ phase transition in phosphatidylcholine lipid bilayers : a disorderorder transition in two dimensions
V. A. Raghunathan (1996)
10.1063/1.1678914
Theory of biomembrane phase transitions
J. Nagle (1973)
10.1016/0304-4157(89)90010-5
Hydration forces between phospholipid bilayers
R. Rand (1989)
10.1103/PHYSREVE.49.4665
Order and disorder in fully hydrated unoriented bilayers of gel-phase dipalmitoylphosphatidylcholine.
Sun (1994)
10.1103/PHYSREVB.22.312
Observation of algebraic decay of positional order in a smectic liquid crystal
J. Als-Nielsen (1980)
10.1016/S0009-3084(98)00068-1
Fluid phase structure of EPC and DMPC bilayers.
H. Petrache (1998)
10.1021/BI00365A034
Area per molecule and distribution of water in fully hydrated dilauroylphosphatidylethanolamine bilayers.
T. McIntosh (1986)
10.1016/j.bpj.2018.11.1237
Structure of gel phase DMPC determined by X-ray diffraction.
S. Tristram-Nagle (2002)
10.1016/0005-2736(85)90448-1
Static and dynamic calorimetric studies on the three kinds of phase transition in the systems of l- and dl-dipalmitoylphosphatidylcholine/water
Michiko Kodama (1985)
10.1016/0005-2736(82)90049-9
Characterization of the sub-transition of hydrated dipalmitoylphosphatidylcholine bilayers: X-ray diffraction study
M. J. Ruocco (1982)
10.1103/PHYSREVE.63.011907
Method for obtaining structure and interactions from oriented lipid bilayers.
Y. Lyatskaya (2001)
X - ray structure determination of L  phase DPPC bilayers
J. F. Nagle (1996)
Dimer models on anisotropic lattices
J. Nagle (1989)
10.1016/S0006-3495(98)77950-0
Determination of the hydrocarbon core structure of fluid dioleoylphosphocholine (DOPC) bilayers by x-ray diffraction using specific bromination of the double-bonds: effect of hydration.
K. Hristova (1998)
10.1016/S0304-4157(00)00016-2
Structure of lipid bilayers.
J. Nagle (2000)
10.1016/S0006-3495(98)77580-0
Structure and interactions of fully hydrated dioleoylphosphatidylcholine bilayers.
S. Tristram-Nagle (1998)
10.1016/S0006-3495(78)85441-1
Lecithin bilayers. Density measurement and molecular interactions.
J. Nagle (1978)
Crystalline physics. remarks on the X-ray scattering of smectic A phases
A Caillé (1972)
Dilatometric studies of the subtransition in DPPC
J F Nagle (1982)
10.1016/S0006-3495(98)77563-0
Phospholipid component volumes: determination and application to bilayer structure calculations.
R. Armen (1998)
10.1021/BI00388A016
Kinetics of the subtransition in dipalmitoylphosphatidylcholine.
S. Tristram-Nagle (1987)
10.1016/S0006-3495(93)81475-9
Measurement of chain tilt angle in fully hydrated bilayers of gel phase lecithins.
S. Tristram-Nagle (1993)
10.1016/S0006-3495(96)79701-1
X-ray structure determination of fully hydrated L alpha phase dipalmitoylphosphatidylcholine bilayers.
J. Nagle (1996)
10.1016/S0006-3495(98)77658-1
Adsorbed to a rigid substrate, dimyristoylphosphatidylcholine multibilayers attain full hydration in all mesophases.
J. Katsaras (1998)
10.1073/PNAS.93.14.7008
Structure of the ripple phase in lecithin bilayers.
W. Sun (1996)
Characterization of the subtransition of hydrated dipalmitoylphosphatidylcholine bilayers. X-ray diffraction study
M J Ruocco (1982)
10.1063/1.1150529
Sample cell capable of 100% relative humidity suitable for x-ray diffraction of aligned lipid multibilayers
J. Katsaras (2000)
Comment on growth of molecular superlattice in fully hydrated DPPC during subgel phase formation
J F Nagle (1998)
10.1016/0005-2736(94)90227-5
Kinetics of subgel formation in DPPC: X-ray diffraction proves nucleation-growth hypothesis.
S. Tristram-Nagle (1994)
1973a. Theory of biomembrane phase transitions
J. F. Nagle (1973)
10.1007/3-798-51084-9_12
The role of water in the hydration force - molecular dynamics simulations
L. Perera (1997)
Static and dynamic calorimetric studies on the three kinds of phase transition in the systems of l-and dl-dipalmitoylphosphtidylcholine/water
M Kodama (1985)
10.1073/PNAS.70.12.3443
Lipid bilayer phase transition: density measurements and theory.
J. Nagle (1973)
10.1021/BI00259A015
Dilatometric studies of the subtransition in dipalmitoylphosphatidylcholine.
Nagle Jf (1982)
New method to obtain structure of biomembranes using diffuse X-ray scattering: application to fluid phase DOPC lipid bilayers
Y Liu (2003)
Simulations of interacting
N. 5060–5063. Gouliaev (1998)
10.1038/scientificamerican01051918-5supp
A differential dilatometer.
D. A. Wilkinson (1978)
Lipid bilayer phase transition: dilatometry and theory
J F Nagle (1973)
10.1039/DC9868100151
Theory of lipid monolayer and bilayer chain-melting phase transitions.
J. Nagle (1986)
Static and dynamic calorimetric studies on the three kinds of phase transition in the systems of land dldipalmitoylphosphtidylcholine / water
M. Kodama (1985)
L B → L C phase transition in phosphatidylcholine lipid bilayers: a disorder-order transition in two dimensions
V A Raghunathan (1996)
10.1016/S0006-3495(01)75941-3
Molecular simulation of dioleoylphosphatidylcholine lipid bilayers at differing levels of hydration.
R. J. Mashl (2001)
10.1103/PHYSREVA.37.3993
Phase transformations in lipids follow classical kinetics with small fractional dimensionalities.
Yang (1988)
10.1021/BI00350A003
Structure of the crystalline bilayer in the subgel phase of dipalmitoylphosphatidylglycerol.
A. Blaurock (1986)
10.1107/S0021889894007867
A Large-Format High-Resolution Area X-ray Detector Based on a Fiber-Optically Bonded Charge-Coupled Device (CCD)
M. Tate (1995)
10.1007/S100510050201
Comment on “Growth of Molecular Superlattice in Fully Hydrated Dipalmitoylphosphatidylcholine during Subgel Phase Formation Process” by H. Takahashi, K. Hatta and I. Hatta
J. Nagle (1998)
10.1073/PNAS.77.9.5060
Scanning calorimetric evidence for a third phase transition in phosphatidylcholine bilayers.
S. Chen (1980)
10.1038/213974a0
Chemistry and Physics of Lipids
C. Adams (1967)
10.1103/PHYSREVE.54.4446
L beta '-->Lc' phase transition in phosphatidylcholine lipid bilayers: A disorder-order transition in two dimensions.
Raghunathan (1996)
X-ray structure determination
J. F. Nagle (1996)
10.1146/ANNUREV.PC.31.100180.001105
Theory of the Main Lipid Bilayer Phase Transition
J. Nagle (1980)



This paper is referenced by
10.1016/j.bpj.2014.10.058
Time-resolved fluorescence in lipid bilayers: selected applications and advantages over steady state.
M. Amaro (2014)
10.1063/1.5120456
Water hydrogen-bonding structure and dynamics near lipid multibilayer surface: Molecular dynamics simulation study with direct experimental comparison.
Euihyun Lee (2019)
10.1074/jbc.M611463200
Interaction of the Mitochondria-targeted Antioxidant MitoQ with Phospholipid Bilayers and Ubiquinone Oxidoreductases*
A. James (2007)
10.1007/978-3-319-19060-0
Membrane Hydration
E. Disalvo (2015)
10.1063/1.1828435
Distance measurements between paramagnetic centers and a planar object by matrix Mims electron nuclear double resonance.
Paul-Philipp Zänker (2005)
Optical characterization of thermal transport from the nanoscale to the macroscale
Aaron J. Schmidt (2008)
10.1021/JM061053F
Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer.
A. Gorfe (2007)
Fluctuations et déstabilisation d'une bicouche lipidique supportée
S. Lecuyer (2006)
10.1073/pnas.0907354106
Measurement of the membrane curvature preference of phospholipids reveals only weak coupling between lipid shape and leaflet curvature
M. M. Kamal (2009)
10.1063/1.4773856
Effects of interleaflet coupling on the morphologies of multicomponent lipid bilayer membranes.
Chloe M. Funkhouser (2013)
10.1016/J.BBAMEM.2007.02.020
Characterization of the conformational and orientational dynamics of ganglioside GM1 in a dipalmitoylphosphatidylcholine bilayer by molecular dynamics simulations.
R. Y. Patel (2007)
10.1039/c6sm00695g
Swelling of phospholipid membranes by divalent metal ions depends on the location of the ions in the bilayers.
Richard J Alsop (2016)
10.1134/S0006350907050016
Water state and diffusion through lipid bilayers: Effect of hydration degree
A. Khakimov (2007)
10.1007/S10973-007-8653-Z
Calorimetric and EPR studies of the thermotropic phase behavior of phospholipid membranes
D. Pentak (2008)
Chemistry and Physics of Lipids
G. Pabsta (2009)
10.1103/PHYSREVLETT.122.248101
Phase Transitions in a Single Supported Phospholipid Bilayer: Real-Time Determination by Neutron Reflectometry.
Y. Gerelli (2019)
10.1021/acs.jpcb.6b02982
Quantifying the Heterogeneous Dynamics of a Simulated Dipalmitoylphosphatidylcholine (DPPC) Membrane.
Neha Shafique (2016)
10.1021/jacs.5b08894
Mechanical Properties of Nanoscopic Lipid Domains.
J. Nickels (2015)
10.1007/s00232-010-9254-5
Comparing Membrane Simulations to Scattering Experiments: Introducing the SIMtoEXP Software
N. Kučerka (2010)
10.1103/PHYSREVE.84.031909
Phase transitions and spatially ordered counterion association in ionic-lipid membranes: a statistical model.
M. Tamashiro (2011)
10.1016/j.biochi.2011.06.027
Lipid hydration and mobility: an interplay between fluorescence solvent relaxation experiments and molecular dynamics simulations.
P. Jurkiewicz (2012)
Influence of the presence of solutes on the structural and dynamical properties of lipid membranes and water[HBNI Th108]
U. Baul (2016)
10.1007/S10483-018-2252-6
Modeling biomembranes and red blood cells by coarse-grained particle methods
H. Li (2017)
10.1016/j.jcis.2016.10.091
Lubrication synergy: Mixture of hyaluronan and dipalmitoylphosphatidylcholine (DPPC) vesicles.
A. Raj (2017)
10.1016/J.VIBSPEC.2018.06.004
Raman spectroscopy for quantification of water-to-lipid ratio in phospholipid suspensions
S. Adichtchev (2018)
10.1201/B16617-3
Soft Matter Physics of Lipid Membrane–Based Assemblies
D. Harries (2014)
10.1016/j.xphs.2016.02.012
A Universal Correlation Predicts Permeability Coefficients of Fluid- and Gel-Phase Phospholipid and Phospholipid-Cholesterol Bilayers for Arbitrary Solutes.
J. Nitsche (2016)
10.1063/1.4895546
Theoretical vibrational sum-frequency generation spectroscopy of water near lipid and surfactant monolayer interfaces.
S. Roy (2014)
10.1016/J.CPLETT.2007.01.023
Interplay between the Belousov–Zhabotinsky reaction–diffusion system and biomimetic matrices
S. Ristori (2007)
SIMULATION OF ROTATIONAL DIFFUSION AND HYDRATION OF LAURDAN IN A DPPC BILAYER
Ryan Frei (2007)
10.1021/jp312845w
Solid-state nuclear magnetic resonance measurements of HIV fusion peptide 13CO to lipid 31P proximities support similar partially inserted membrane locations of the α helical and β sheet peptide structures.
C. M. Gabrys (2013)
10.1007/3-540-31618-3_1
Membrane Protein Simulations: Modelling a Complex Environment
P. Bond (2006)
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