← Back to Search
Preparation And Optimization Of Pickering Emulsion Stabilized By Chitosan-tripolyphosphate Nanoparticles For Curcumin Encapsulation
B. R. Shah, Y. Li, Weiping Jin, Yaping An, L. He, Zhenshun Li, Wei Xu, Bin Li
Published 2016 · Chemistry
Download PDFAnalyze on Scholarcy
Abstract In recent decades the preparation of Pickering emulsion has attracted much attention due to a wide range of its useful applicability in cosmetic, food and pharmaceutical industries. The objective of the current study was to optimize the preparation of Chitosan-tripolyphosphate (CS-TPP) nanoparticles stabilized Pickering emulsion as a delivery system for curcumin. The CS-TPP nanoparticles (NPs) were prepared by the ionic gelation techniques between CS and TPP. The effect of preparation conditions, storage time, pH and salt on the stability of Pickering emulsion was evaluated. Then curcumin was encapsulated and its stability and release kinetics were evaluated based on spectrophotometric measurements to quantify the amount of encapsulated curcumin in the Pickering emulsion as a function of time. Overall, these results showed that after optimization, Pickering emulsions could be fabricated with uniform particle size distribution, long-term stability, high stability against pH, salts and can be an effective route for delivery of bioactive compounds.
This paper references
Pickering Emulsions Stabilized by Monodisperse Latex Particles: Effects of Particle Size
B. P. B. and (2001)
Triglyceride-water emulsions stabilised by starch-based nanoparticles
Y. Tan (2014)
Monodisperse chitosan nanoparticles for mucosal drug delivery.
H. Zhang (2004)
The storage stability of chitosan/tripolyphosphate nanoparticles in a phosphate buffer
Min Lang Tsai (2011)
Enhanced stability of curcumin in colloidosomes stabilized by silica aggregates
Y. Zhao (2014)
PS colloidal particles stabilized by graphene oxide.
X. Song (2011)
Chitosan nanofibers from an easily electrospinnable UHMWPEO-doped chitosan solution system.
Y. Zhang (2008)
Interactions between liposomes and chitosan
I. Henriksen (1994)
Food emulsions and foams: Stabilization by particles
E. Dickinson (2010)
Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications.
J. Berger (2004)
Fate of curcumin encapsulated in silica nanoparticle stabilized Pickering emulsion during storage and simulated digestion
Rohan V Tikekar (2013)
Curcumin: Getting Back to the Roots
S. Shishodia (2005)
Topical delivery of lipophilic drugs from o/w Pickering emulsions.
J. Frelichowska (2009)
pH-dependent characteristics of gel-like emulsion stabilized by threadfin bream sarcoplasmic proteins
Bung-Orn Hemung (2013)
Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems.
J. Cui (2009)
Effects of oil type and aqueous phase composition on oil–water mixtures containing particles of intermediate hydrophobicity
B. Binks (2000)
Hydrophobically modified ethyl(hydroxyethyl)cellulose as stabilizer and emulsifying agent in macroemulsions
Maria Karlberg (2005)
Curcuminoids-loaded lipid nanoparticles: novel approach towards malaria treatment.
Aditya P Nayak (2010)
beta-Cyclodextrin-curcumin self-assembly enhances curcumin delivery in prostate cancer cells.
Murali M Yallapu (2010)
Optimization of fabrication parameters to produce chitosan-tripolyphosphate nanoparticles for delivery of tea catechins.
B. Hu (2008)
Recent advances on chitosan-based micro- and nanoparticles in drug delivery.
S. Agnihotri (2004)
Preparation of alginate coated chitosan microparticles for vaccine delivery
X. Li (2008)
Octadecenylsuccinic anhydride pickering emulsion stabilized by γ-methacryloxy propyl trimethoxysilane grafted montmorillonite
Yu Dehai (2013)
Why is chitosan mucoadhesive?
Ioannis A Sogias (2008)
Emulsions stabilized with solid nanoparticles: Pickering emulsions
Y. Chevalier (2013)
Food Emulsions: Principles, Practice, and Techniques
D. J. Mcclements (1998)
Encapsulation of curcumin in cationic micelles suppresses alkaline hydrolysis.
Mandy H M Leung (2008)
Particles as surfactants—similarities and differences
B. Binks (2002)
Chitosan-tripolyphosphate submicron particles as the carrier of entrapped rutin.
K. Konecsni (2012)
Preparation and Characterization of Venlafaxine Hydrochloride-Loaded Chitosan Nanoparticles and In Vitro Release of Drug
S. Shah (2009)
Effect of chitosan on the stability and properties of modified lecithin stabilized oil-in-water monodisperse emulsion prepared by microchannel emulsification
A. M. Chuah (2009)
The influence of multivalent phosphate structure on the properties of ionically cross-linked chitosan films for controlled drug release.
X. Shu (2002)
Antibacterial activity of chitosan tripolyphosphate nanoparticles loaded with various metal ions
W. Du (2009)
The effect of prolonged storage at different temperatures on the particle size distribution of tripolyphosphate (TPP)-chitosan nanoparticles
Gordon A. Morris (2011)
This paper is referenced by
Fabrication and characterization of Pickering emulsion stabilized by soy protein isolate-chitosan nanoparticles.
H. Yang (2020)
Novel polysaccharide-polypeptides nanocomplexes: assembly, characterization, and applications in delivery of black tea polyphenols
Y. Jiang (2017)
Two-Step Optimization to Develop a Transdermal Film Loaded With Dapoxetine Nanoparticles: A Promising Technique to Improve Drug Skin Permeation
T. Ahmed (2020)
Gentamicin decorated phosphatidylcholine-chitosan nanoparticles against biofilms and intracellular bacteria.
Yuanhao Qiu (2020)
Encapsulation optimization of lemon balm antioxidants in calcium alginate hydrogels
Samira Najafi-Soulari (2016)
A glycated whey protein isolate-epigallocatechin gallate nanocomplex enhances the stability of emulsion delivery of β-carotene during simulated digestion.
Q. Wang (2019)
Recent advances in emulsion-based delivery approaches for curcumin: From encapsulation to bioaccessibility
Andrea Araiza-Calahorra (2018)
Bioaccessibility and antioxidant activity of curcumin after encapsulated by nano and Pickering emulsion based on chitosan-tripolyphosphate nanoparticles.
B. R. Shah (2016)
Curcumin, a Compound from Natural Sources, a True Scientific Challenge – A Review
Z. Stanić (2016)
Amorphous nano-curcumin stabilized oil in water emulsion: Physico chemical characterization.
N. P. Aditya (2017)
Magnetic cellulose nanocrystal stabilized Pickering emulsions for enhanced bioactive release and human colon cancer therapy.
L. Low (2019)
CURCUMIN NANO-THERAPEUTICS FOR CANCER CHEMOTHERAPY: PROMISES AND CHALLENGES FOR THE FUTURE
M. Das (2016)
Oil-in-Water Emulsions Stabilized by Saponified Epoxidized Soybean Oil-Grafted Hydroxyethyl Cellulose.
Xujuan Huang (2017)
Pickering emulsions stabilized with cashew gum nanoparticles as indomethacin carrier.
Mayrla R Lima Cardial (2019)
Chitosan-based nanoparticles for improved anticancer efficacy and bioavailability of mifepristone
H. Zhang (2016)
Enhanced Curcumin Bioavailability through Nonionic Surfactant/Caseinate Mixed Nanoemulsions.
Francesca Cuomo (2019)
l-Arginine/l-lysine functionalized chitosan-casein core-shell and pH-responsive nanoparticles: fabrication, characterization and bioavailability enhancement of hydrophobic and hydrophilic bioactive compounds.
Zhiyang Du (2020)
Foams for Food Applications
A. L. Ellis (2018)
Chitosan based Pickering emulsion as a promising approach for topical application of rutin in a solubilized form intended for wound healing: In vitro and in vivo study.
M. H. Asfour (2017)
CURCUMIN NANO-THERAPEUTICS FOR CANCER CHEMOTHERAPY: PROMISES AND CHALLENGES FOR THE FUTURE
↓ Telomerase (2016)
Characterization of Nano Chitosan-Cucumber Suri (Cucumis melo L.) Seeds with Sodium Tripolyphosphate as Crosslinker
Rissa Laila Vifta (2019)
Bioadhesive hydrocaffeic acid modified chitosan colloidal particles using as particulate emulsifiers
Rongli Zhang (2019)
Curcumin-loaded chitosan/carboxymethyl starch/montmorillonite bio-nanocomposite for reduction of dental bacterial biofilm formation.
Shabnam Jahanizadeh (2017)
Pickering stabilized nanocellulose-alginate: A diosgenin-mediated delivery of quinalizarin as a potent cyto-inhibitor in human lung/breast cancer cell lines.
Sevinc Ilkar Erdagi (2020)
Fabrication and characterization of citral-loaded oil-in-water Pickering emulsions stabilized by chitosan-tripolyphosphate particles.
H. Tian (2019)
Encapsulation of Vitamin D3 in Pickering Emulsion Stabilized by Nanofibrillated Mangosteen Cellulose: Effect of Environmental Stresses.
Wiphada Mitbumrung (2019)
Using Flammulina velutipes derived chitin-glucan nanofibrils to stabilize palm oil emulsion:A novel food grade Pickering emulsifier.
J. Xiao (2020)
Encapsulation of probiotic Lactobacillus acidophilus by ionic gelation with electrostatic extrusion for enhancement of survival under simulated gastric conditions and during refrigerated storage
J. U. Kim (2017)
Colloidal aspects of digestion of Pickering emulsions: Experiments and theoretical models of lipid digestion kinetics.
A. Sarkar (2019)
Pickering emulsions stabilized by hydrophobically modified hemp powders: the effect of formula compositions on emulsifying capability and stability
Wenhua Ou (2019)
Fabrication of chitosan gel droplets via crosslinking of inverse Pickering emulsifications.
Y. Zhang (2018)
Effect of polyanions variation on the particle size of chitosan nanoparticle prepared by ionic gelation method
Evi Triwulandari (2018)See more