Online citations, reference lists, and bibliographies.
← Back to Search

Recent Progresses In Graphene Based Bio-functional Nanostructures For Advanced Biological And Cellular Interfaces

Chuanxiong Nie, Lang Ma, Shuang Li, Xin Fan, Y. Yang, Chong Cheng, W. Zhao, Changsheng Zhao
Published 2019 · Materials Science

Cite This
Download PDF
Analyze on Scholarcy
Share
Abstract Currently, abundant efforts have been devoted to research on graphene in interdisciplinary applications due to their unique physicochemical, electronic and biological properties. Accompanying the rapid developments of graphene, it is highly important to explore graphene based bio-functional nanostructures (G-BFNs) to bridge the gap between the fundamental advantages of graphene and the requirements in designing hybridized biomaterials. Here, this review aims to outline and summarize the recent advancements in fabricating G-BFNs for advanced biological and cellular interfaces. We first discuss the general protocols for the synthesis of G-BFNs, especially diverse facile and eco-friendly strategies. Then, we carefully summarize the current developed G-BFNs based on their nanostructures and biofunctionalities, such as physiologically-stability, stimuli-responsibility, graphene-inorganic nanohybrids, functional nano-inks, nacre-like layered composites, macroporous scaffolds, 3D printed microlattices, and injectable hydrogels. Moreover, biointeractions at the interfaces of G-BFNs with viruses, bacteria and stem cells, and the relevant biocompatibilities are also highlighted. Furthermore, the emerging applications and future perspectives of G-BFNs in nanotherapeutics, anti-pathogens, tissue regeneration, and monitoring biosensors are carefully discussed. We envision that such a timely and cutting-edge review will not only take a step towards the development of G-BFNs but also inspire new opportunities by using emerged nanomaterials for biological and cellular interfaces.
This paper references
10.1016/J.CARBON.2013.09.016
One-pot synthesis of graphene/hydroxyapatite nanorod composite for tissue engineering
Zengjie Fan (2014)
10.1021/acsnano.6b07311
Graphene Oxide Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents.
J. Zhu (2017)
10.1016/j.actbio.2017.01.027
Bioinspired and biocompatible carbon nanotube-Ag nanohybrid coatings for robust antibacterial applications.
Chuanxiong Nie (2017)
10.1002/ADFM.201604096
Ultrafine Graphene Nanomesh with Large On/Off Ratio for High‐Performance Flexible Biosensors
Y. Yang (2017)
10.1038/nnano.2016.38
A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy.
H. Lee (2016)
10.1039/c2cs35342c
Nano-graphene in biomedicine: theranostic applications.
K. Yang (2013)
10.1021/acsnano.7b02706
Fatigue Resistant Bioinspired Composite from Synergistic Two-Dimensional Nanocomponents.
Sijie Wan (2017)
10.1002/adma.201400523
Guiding stem cell differentiation into oligodendrocytes using graphene-nanofiber hybrid scaffolds.
S. Shah (2014)
10.1002/adma.201602547
Carbon-Based Microbial-Fuel-Cell Electrodes: From Conductive Supports to Active Catalysts.
S. Li (2017)
10.1016/j.jconrel.2014.06.026
Reduced graphene oxide nanosheets coated with an anti-angiogenic anticancer low-molecular-weight heparin derivative for delivery of anticancer drugs.
G. Shim (2014)
10.1002/anie.201306871
Polyaniline-coupled multifunctional 2D metal oxide/hydroxide graphene nanohybrids.
Shuang Li (2013)
10.1016/J.NANTOD.2018.12.003
Laser-derived graphene: A three-dimensional printed graphene electrode and its emerging applications
Narendra Kurra (2019)
10.1002/anie.201702076
Ultrafast Delamination of Graphite into High-Quality Graphene Using Alternating Currents.
S. Yang (2017)
10.1002/smll.201401706
Virus capture and destruction by label-free graphene oxide for detection and disinfection applications.
Zhiyong Song (2015)
10.1002/adma.201506410
2D-Crystal-Based Functional Inks.
F. Bonaccorso (2016)
10.1021/jacs.5b12950
Pathogen Inhibition by Multivalent Ligand Architectures.
Sumati Bhatia (2016)
10.1002/adma.201302219
Axonal alignment and enhanced neuronal differentiation of neural stem cells on graphene-nanoparticle hybrid structures.
Aniruddh Solanki (2013)
10.1016/J.CARBON.2013.09.015
Accelerated differentiation of neural stem cells into neurons on ginseng-reduced graphene oxide sheets
O. Akhavan (2014)
10.1039/c3an01796f
Effects of surface charges of graphene oxide on neuronal outgrowth and branching.
Q. Tu (2014)
10.1021/JP2102226
Simultaneous Reduction and Surface Functionalization of Graphene Oxide for Hydroxyapatite Mineralization
H. Liu (2012)
10.1002/ADFM.201701513
Highly Elastic Graphene‐Based Electronics Toward Electronic Skin
Y. J. Yun (2017)
10.1038/nmat3776
Stimuli-responsive nanocarriers for drug delivery.
S. Mura (2013)
10.1039/c5cs00569h
Bioinspired polymer vesicles and membranes for biological and medical applications.
C. Palivan (2016)
10.1016/J.NANTOD.2016.12.006
Photoluminescence mechanism in graphene quantum dots: Quantum confinement effect and surface/edge state
S. Zhu (2017)
10.1021/acsnano.6b07352
Biomimetic Phospholipid Membrane Organization on Graphene and Graphene Oxide Surfaces: A Molecular Dynamics Simulation Study.
Nathalie Willems (2017)
10.1021/acsnano.8b00304
Generalized 3D Printing of Graphene-Based Mixed-Dimensional Hybrid Aerogels.
Xingwei Tang (2018)
10.1021/la904014z
Graphene oxide as a matrix for enzyme immobilization.
J. Zhang (2010)
10.1002/smll.201801606
Recent Advances in Synthesis and Applications of 2D Junctions.
Yang Ma (2018)
10.3144/EXPRESSPOLYMLETT.2017.8
Layer-by-layer gelatin/chitosan polyelectrolyte coated nanoparticles on Ti implants for prevention of implant-associated infections
Tanatchaporn Sangfai (2017)
10.1002/adma.201200452
Bio-inspired nacre-like composite films based on graphene with superior mechanical, electrical, and biocompatible properties.
Y. Li (2012)
10.1002/adma.201204419
Incorporating graphene oxide and gold nanoclusters: a synergistic catalyst with surprisingly high peroxidase-like activity over a broad pH range and its application for cancer cell detection.
Yu Tao (2013)
10.1016/J.CARBON.2014.11.029
Covalent conjugation of mechanically stiff graphene oxide flakes to three-dimensional collagen scaffolds for osteogenic differentiation of human mesenchymal stem cells
S. Kang (2015)
10.1002/ADFM.201801056
Biomimetic Ultralight, Highly Porous, Shape‐Adjustable, and Biocompatible 3D Graphene Minerals via Incorporation of Self‐Assembled Peptide Nanosheets
Keheng Li (2018)
10.1016/J.NANTOD.2018.02.009
Graphene/Semiconductor Hybrid Heterostructures for Optoelectronic Device Applications
C. Xie (2018)
10.1002/adma.201403322
Ultratough, ultrastrong, and highly conductive graphene films with arbitrary sizes.
M. Zhang (2014)
10.1021/nl400368v
Strong two-photon-induced fluorescence from photostable, biocompatible nitrogen-doped graphene quantum dots for cellular and deep-tissue imaging.
Qian Liu (2013)
10.1002/chem.201801085
Black Phosphorus Quantum Dots Gated, Carbon-Coated Fe3 O4 Nanocapsules (BPQDs@ss-Fe3 O4 @C) with Low Premature Release Could Enable Imaging-Guided Cancer Combination Therapy.
M. Zhang (2018)
10.1021/MA102371D
General Avenue to Individually Dispersed Graphene Oxide-Based Two-Dimensional Molecular Brushes by Free Radical Polymerization
Lanyan Kan (2011)
10.1021/bm100470q
Fabrication, mechanical properties, and biocompatibility of graphene-reinforced chitosan composites.
Hailong Fan (2010)
10.1016/J.NANTOD.2016.12.011
Covalent three-dimensional networks of graphene and carbon nanotubes: synthesis and environmental applications
Archi Dasgupta (2017)
10.1021/acsnano.7b05921
Scalable Production of Graphene-Based Wearable E-Textiles
N. Karim (2017)
10.1021/acsnano.5b05373
Ultrafast Synthesis of Multifunctional N-Doped Graphene Foam in an Ethanol Flame.
Xusheng Du (2016)
10.1021/acs.chemrev.5b00417
Supramolecular Architectures of Dendritic Amphiphiles in Water.
B. Thota (2016)
10.1016/j.biomaterials.2015.11.041
Hybrid graphene/Au activatable theranostic agent for multimodalities imaging guided enhanced photothermal therapy.
S. Gao (2016)
10.1002/adma.201302810
3D graphene oxide-polymer hydrogel: near-infrared light-triggered active scaffold for reversible cell capture and on-demand release.
W. Li (2013)
10.1002/adma.201503045
Multifunctional Pristine Chemically Modified Graphene Films as Strong as Stainless Steel.
Miao Zhang (2015)
10.1002/anie.201713387
A Water-Soluble Warped Nanographene: Synthesis and Applications for Photoinduced Cell Death.
Hsing-An Lin (2018)
10.1016/J.MATTOD.2015.12.004
Mesoscale design of multifunctional 3D graphene networks
P. Sherrell (2016)
10.1002/ADFM.201703096
Self‐Healing Graphene Oxide Based Functional Architectures Triggered by Moisture
Huhu Cheng (2017)
10.1039/B613014N
The growing applications of click chemistry.
J. Moses (2007)
10.1002/adma.201702149
Electron Transfer Directed Antibacterial Properties of Graphene Oxide on Metals.
Sunita Panda (2018)
10.1002/adma.201301046
Non-invasive synergistic treatment of brain tumors by targeted chemotherapeutic delivery and amplified focused ultrasound-hyperthermia using magnetic nanographene oxide.
Hung-Wei Yang (2013)
10.1126/SCIENCE.1147241
Mussel-Inspired Surface Chemistry for Multifunctional Coatings
H. Lee (2007)
10.1002/marc.200900641
Polymer Brushes via Controlled, Surface-Initiated Atom Transfer Radical Polymerization (ATRP) from Graphene Oxide.
S. Lee (2010)
10.1021/acsnano.7b05215
Two-Dimensional Graphene Augments Nanosonosensitized Sonocatalytic Tumor Eradication.
Chen Dai (2017)
10.1039/C3GC42545B
Co-immobilization of multi-enzyme on control-reduced graphene oxide by non-covalent bonds: an artificial biocatalytic system for the one-pot production of gluconic acid from starch
Fuhua Zhao (2014)
10.1002/ADFM.201606477
Functionalized Graphene as Extracellular Matrix Mimics: Toward Well-Defined 2D Nanomaterials for Multivalent Virus Interactions
M. F. Gholami (2017)
10.1002/ADFM.201203637
Self-Supporting Graphene Hydrogel Film as an Experimental Platform to Evaluate the Potential of Graphene for Bone Regeneration
Jiayu Lu (2013)
10.1021/acsnano.7b00370
Smart Contact Lenses with Graphene Coating for Electromagnetic Interference Shielding and Dehydration Protection.
S. Lee (2017)
10.1039/C2JM14718A
The preparation of functionalized graphene oxide for targeted intracellular delivery of siRNA
X. Yang (2012)
10.1039/C1JM10749F
Green and facile synthesis of highly biocompatible graphene nanosheets and its application for cellular imaging and drug delivery
Kunping Liu (2011)
10.1016/j.biomaterials.2017.10.004
When stem cells meet graphene: Opportunities and challenges in regenerative medicine.
Kenry (2018)
10.1002/adma.201301082
Cell-laden microengineered and mechanically tunable hybrid hydrogels of gelatin and graphene oxide.
S. R. Shin (2013)
10.1016/j.biomaterials.2012.06.064
The interactions between pristine graphene and macrophages and the production of cytokines/chemokines via TLR- and NF-κB-related signaling pathways.
Hejiang Zhou (2012)
10.1002/adma.201202211
Uniform polypyrrole nanoparticles with high photothermal conversion efficiency for photothermal ablation of cancer cells.
Zhengbao Zha (2013)
10.1021/bc200397j
Graphene oxide-polyethylenimine nanoconstruct as a gene delivery vector and bioimaging tool.
Hyunwoo Kim (2011)
10.1002/anie.201507070
Endoperoxides Revealed as Origin of the Toxicity of Graphene Oxide.
Hanna Pieper (2016)
10.4028/www.scientific.net/JNanoR.45.199
Reduced Graphene Oxide Paper: Fabrication by a Green Thermal Reduction Method and Preliminary Study of its In Vitro Cytotoxicity
Xin Wang (2017)
10.1002/adma.201706435
A Bioinspired Interface Design for Improving the Strength and Electrical Conductivity of Graphene-Based Fibers.
T. Ma (2018)
10.1002/ADFM.201707024
Direct 3D Printing of Ultralight Graphene Oxide Aerogel Microlattices
Y. Jiang (2018)
10.1016/j.jhazmat.2018.07.107
Antibacterial biocompatible arginine functionalized mono-layer graphene: No more risk of silver toxicity.
A. R. Rafieerad (2018)
10.1039/C5GC01979F
Biocompatible reduced graphene oxide sheets with superior water dispersibility stabilized by cellulose nanocrystals and their polyethylene oxide composites
Y. Ye (2016)
10.1016/j.biomaterials.2014.03.087
Simulation and analysis of cellular internalization pathways and membrane perturbation for graphene nanosheets.
J. Mao (2014)
10.1002/ADFM.201501250
Carbon and Graphene Quantum Dots for Optoelectronic and Energy Devices: A Review
Xiao-ming Li (2015)
10.1002/anie.201302048
Near-infrared- and pH-responsive system for reversible cell adhesion using graphene/gold nanorods functionalized with i-motif DNA.
Wangrong Li (2013)
10.1039/C0JM04043F
High strength graphene oxide/polyvinyl alcohol composite hydrogels
L. Zhang (2011)
10.1002/anie.201307830
Written-in conductive patterns on robust graphene oxide biopaper by electrochemical microstamping.
Kesong Hu (2013)
10.1021/nl1024744
Derivitization of pristine graphene with well-defined chemical functionalities.
Li-hong Liu (2010)
10.1016/j.addr.2016.04.028
Toxicology of graphene-based nanomaterials.
G. Lalwani (2016)
10.1039/C1JM13356J
Graphene supported Au-Pd bimetallic nanoparticles with core-shell structures and superior peroxidase-like activities
H. Chen (2011)
10.1021/la903265p
Water-soluble graphene covalently functionalized by biocompatible poly-L-lysine.
Changsheng Shan (2009)
10.1002/adma.201104964
Multimodal imaging guided photothermal therapy using functionalized graphene nanosheets anchored with magnetic nanoparticles.
K. Yang (2012)
10.1016/j.jconrel.2016.02.015
Assessing biocompatibility of graphene oxide-based nanocarriers: A review.
Siaw Fui Kiew (2016)
10.1021/nl100996u
Graphene in mice: ultrahigh in vivo tumor uptake and efficient photothermal therapy.
K. Yang (2010)
10.1002/ADFM.201702493
High‐Performance Wearable Micro‐Supercapacitors Based on Microfluidic‐Directed Nitrogen‐Doped Graphene Fiber Electrodes
Guan Wu (2017)
10.1021/cr400532z
Functional nanomaterials for phototherapies of cancer.
Liang Cheng (2014)
10.1021/acsami.7b16283
Mussel-Inspired Synthesis of NIR-Responsive and Biocompatible Ag-Graphene 2D Nanoagents for Versatile Bacterial Disinfections.
X. Fan (2018)
10.1021/MA101526K
Dopamine-Induced Reduction and Functionalization of Graphene Oxide Nanosheets
L. Xu (2010)
10.1039/C3NJ01641B
Tunable and selective detection of cancer cells using a betainized zwitterionic polymer with BODIPY and graphene oxide
So Yeong Lee (2014)
10.1002/ADFM.201604620
Redox Sensitive Hyaluronic Acid‐Decorated Graphene Oxide for Photothermally Controlled Tumor‐Cytoplasm‐Selective Rapid Drug Delivery
Tingjie Yin (2017)
10.1002/smll.201602133
Graphene Oxide Nanosheets Retard Cellular Migration via Disruption of Actin Cytoskeleton.
Xin Tian (2017)
10.1021/bm500602w
Heparin-like properties of sulfated alginates with defined sequences and sulfation degrees.
Øystein Arlov (2014)
10.1002/ADFM.201401300
Layer-by-layer assembly of 3D tissue constructs with functionalized graphene.
S. R. Shin (2014)
10.1002/smll.201801883
Large-Stroke Electrochemical Carbon Nanotube/Graphene Hybrid Yarn Muscles.
J. Qiao (2018)
10.1021/ACS.CHEMMATER.5B00774
Gram-Scale Synthesis of Graphene Quantum Dots from Single Carbon Atoms Growth via Energetic Material Deflagration
Yousong Liu (2015)
10.1016/J.SNB.2018.11.152
In-situ electrochemically deposited Fe3O4 nanoparticles onto graphene nanosheets as amperometric amplifier for electrochemical biosensing applications
Thi Ngoc Nga Dau (2019)
10.1021/acsnano.7b07737
Surface Oxidation of Graphene Oxide Determines Membrane Damage, Lipid Peroxidation, and Cytotoxicity in Macrophages in a Pulmonary Toxicity Model.
Ruibin Li (2018)
10.1038/nature10381
Synthesis, assembly and applications of semiconductor nanomembranes
J. Rogers (2011)
10.1002/smll.201302182
Controlling mechanical properties of cell-laden hydrogels by covalent incorporation of graphene oxide.
Chaenyung Cha (2014)
10.1002/smll.201802625
Stretchable Transparent Conductive Films from Long Carbon Nanotube Metals.
Peng Wang (2018)
10.1021/jacs.5b11411
Mechanisms of the Antimicrobial Activities of Graphene Materials.
Xuefeng Zou (2016)
10.1002/adma.201100905
Enhancing the photothermal stability of plasmonic metal nanoplates by a core-shell architecture.
X. Huang (2011)
10.1002/adma.201702831
Topological Design of Ultrastrong and Highly Conductive Graphene Films.
Yeye Wen (2017)
10.1021/acs.nanolett.7b01215
Effect of Graphene on Nonneuronal and Neuronal Cell Viability and Stress.
S. K. Rastogi (2017)
10.1002/ADFM.201000540
Self‐Assembled Graphene–Enzyme Hierarchical Nanostructures for Electrochemical Biosensing
Q. Zeng (2010)
10.1002/smll.201601001
From Graphite to Graphene Oxide and Graphene Oxide Quantum Dots.
B. Liu (2017)
10.1002/adma.201502866
Rapid and Versatile Photonic Annealing of Graphene Inks for Flexible Printed Electronics.
E. Secor (2015)
10.1002/adma.201700909
Graphene in the Design and Engineering of Next-Generation Neural Interfaces.
K. Kostarelos (2017)
10.1002/anie.201803076
Wrapping Nanocellulose Nets around Graphene Oxide Sheets.
R. Xiong (2018)
10.1021/CM503782P
Processable Aqueous Dispersions of Graphene Stabilized by Graphene Quantum Dots
P. He (2015)
10.1021/acs.chemrev.7b00194
Form Follows Function: Nanoparticle Shape and Its Implications for Nanomedicine.
Calum Kinnear (2017)
10.1016/j.biomaterials.2016.12.022
Graphene quantum dots with nitrogen-doped content dependence for highly efficient dual-modality photodynamic antimicrobial therapy and bioimaging.
Wen-Shuo Kuo (2017)
10.1021/cr500537t
Design, synthesis, and characterization of graphene-nanoparticle hybrid materials for bioapplications.
P. T. Yin (2015)
10.1016/J.PROGPOLYMSCI.2017.12.001
Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applications
Wensi Zhang (2017)
10.1021/acs.nanolett.7b00093
Mimicking Horseradish Peroxidase and NADH Peroxidase by Heterogeneous Cu2+-Modified Graphene Oxide Nanoparticles.
Shan Wang (2017)
10.1002/adma.201502486
Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy.
Jibin Song (2015)
10.1016/j.bios.2015.01.039
An ultrasensitive electrochemical DNA biosensor based on graphene/Au nanorod/polythionine for human papillomavirus DNA detection.
Huayu Huang (2015)
10.1021/ja806499w
Diazonium functionalization of surfactant-wrapped chemically converted graphene sheets.
Jay R. Lomeda (2008)
10.1038/nature11458
A roadmap for graphene
K. Novoselov (2012)
10.1016/j.biomaterials.2014.02.011
Magnetic and fluorescent graphene for dual modal imaging and single light induced photothermal and photodynamic therapy of cancer cells.
Ganesh Gollavelli (2014)
10.1002/anie.201410139
Biologically inspired dynamic material systems.
A. Studart (2015)
10.1016/J.CEJ.2013.05.019
Biomimetic assembly of polydopamine-layer on graphene: Mechanisms, versatile 2D and 3D architectures and pollutant disposal
Chong Cheng (2013)
10.1002/smll.201603935
Simulated Sunlight-Mediated Photodynamic Therapy for Melanoma Skin Cancer by Titanium-Dioxide-Nanoparticle-Gold-Nanocluster-Graphene Heterogeneous Nanocomposites.
Y. Cheng (2017)
10.1002/adma.201605479
Pyroprotein-Based Electronic Textiles with High Stability.
J. W. Jeon (2017)
10.1021/acsami.7b18459
Chemical Approach to Ultrastiff, Strong, and Environmentally Stable Graphene Films.
Mingmao Wu (2018)
10.1016/j.biomaterials.2014.10.065
Hyaluronic acid-modified Fe3O4@Au core/shell nanostars for multimodal imaging and photothermal therapy of tumors.
J. Li (2015)
10.1002/smll.201801983
Electroactive Scaffolds for Neurogenesis and Myogenesis: Graphene-Based Nanomaterials.
Zhongyang Zhang (2018)
10.1021/cr500304f
Broad family of carbon nanoallotropes: classification, chemistry, and applications of fullerenes, carbon dots, nanotubes, graphene, nanodiamonds, and combined superstructures.
V. Georgakilas (2015)
10.1021/ja803688x
PEGylated nanographene oxide for delivery of water-insoluble cancer drugs.
Zhuang Liu (2008)
10.1016/J.MATTOD.2016.11.002
Learning from nature: constructing high performance graphene-based nanocomposites
Shanshan Gong (2017)
10.1002/ADFM.201702891
Recent Advances in Sensing Applications of Graphene Assemblies and Their Composites
T. Tung (2017)
10.1021/acsnano.7b07528
Highly Self-Healable 3D Microsupercapacitor with MXene-Graphene Composite Aerogel.
Y. Yue (2018)
10.1016/J.MEMSCI.2014.11.005
Novel heparin-mimicking polymer brush grafted carbon nanotube/PES composite membranes for safe and efficient blood purification
Chuanxiong Nie (2015)
10.1021/ACS.JPCC.5B05251
Graphene Oxide and Pluronic Copolymer Aggregates–Possible Route to Modulate the Adsorption of Fluorophores and Imaging of Live Cells
N. Kundu (2015)
10.3390/ijerph13040430
Antiviral Activity of Graphene–Silver Nanocomposites against Non-Enveloped and Enveloped Viruses
Yi-Ning Chen (2016)
10.1038/nature12763
Face-to-face transfer of wafer-scale graphene films
L. Gao (2014)
10.1039/C1GC15393E
From graphite oxide to highly water dispersible functionalized graphene by single step plant extract-induced deoxygenation
D. Mhamane (2011)
10.1016/j.biomaterials.2017.10.034
Mitochondrial specific photodynamic therapy by rare-earth nanoparticles mediated near-infrared graphene quantum dots.
Dandan Zhang (2018)
10.1016/J.PMATSCI.2017.08.004
Graphene: A versatile platform for nanotheranostics and tissue engineering
R. Bai (2018)
10.1016/J.NANTOD.2016.08.006
Shining carbon dots: Synthesis and biomedical and optoelectronic applications
F. Yuan (2016)
10.1002/adma.201203229
New horizons for diagnostics and therapeutic applications of graphene and graphene oxide.
Lingyan Feng (2013)
10.1002/anie.201407113
Mussel-inspired dendritic polymers as universal multifunctional coatings.
Q. Wei (2014)
10.1002/adma.201304737
A universal approach to crosslinked hierarchical polymer multilayers as stable and highly effective antifouling coatings.
Q. Wei (2014)
10.1021/MA201620W
Supramolecular Hybrid Hydrogels from Noncovalently Functionalized Graphene with Block Copolymers
Jianghua Liu (2011)
10.1002/ADMA.200803633
Aqueous Stabilization and Self‐Assembly of Graphene Sheets into Layered Bio‐Nanocomposites using DNA
A. Patil (2009)
10.1088/0022-3727/47/9/094012
Functionalization of graphene nanoribbons
Boštjan Genorio (2014)
10.1021/acs.chemrev.6b00520
Functional Graphene Nanomaterials Based Architectures: Biointeractions, Fabrications, and Emerging Biological Applications.
Chong Cheng (2017)
10.1016/j.biomaterials.2011.07.071
Synergistic effect of chemo-photothermal therapy using PEGylated graphene oxide.
W. Zhang (2011)
10.1016/J.CARBPOL.2010.08.038
Preparation of chitosan/graphene oxide composite film with enhanced mechanical strength in the wet state
D. Han (2011)
10.1002/ADFM.201701837
Combination of Surface Charge and Size Controls the Cellular Uptake of Functionalized Graphene Sheets
Zhaoxu Tu (2017)
10.1002/ADFM.201301951
A Multi‐synergistic Platform for Sequential Irradiation‐Activated High‐Performance Apoptotic Cancer Therapy
Zhaowei Chen (2014)
10.1002/adma.201705452
A Water-Processable and Bioactive Multivalent Graphene Nanoink for Highly Flexible Bioelectronic Films and Nanofibers.
C. Cheng (2018)
10.1021/bm3014999
General and biomimetic approach to biopolymer-functionalized graphene oxide nanosheet through adhesive dopamine.
Chong Cheng (2012)
10.1002/9781119069447.CH11
Toxicity Studies and Biomedical Applications of Graphene Oxide
Larisa Kovbasyuk (2016)
10.1021/bm101031a
Blood compatible graphene/heparin conjugate through noncovalent chemistry.
D. Lee (2011)
10.1021/acsnano.6b03358
The Effects of Extensive Glomerular Filtration of Thin Graphene Oxide Sheets on Kidney Physiology.
Dhifaf A Jasim (2016)
10.1007/s40820-018-0206-4
A Review on Graphene-Based Nanomaterials in Biomedical Applications and Risks in Environment and Health
Thabitha P. Dasari Shareena (2018)
10.1002/adma.201501177
Reversible and Rewritable Surface Functionalization and Patterning via Photodynamic Disulfide Exchange.
X. Du (2015)
10.1002/adma.201503319
Soft Graphene Nanofibers Designed for the Acceleration of Nerve Growth and Development.
Zhang-Qi Feng (2015)
10.1002/adma.201605529
Programmable Nano-Bio Interfaces for Functional Biointegrated Devices.
P. Cai (2017)
10.1021/cr100440g
Protein-nanoparticle interactions: opportunities and challenges.
M. Mahmoudi (2011)
10.1016/j.tibtech.2014.03.004
Lab-on-a-chip technologies for stem cell analysis.
P. Ertl (2014)
10.1021/acsnano.7b02182
Graphene Electronic Tattoo Sensors.
Shideh Kabiri Ameri (2017)
10.1002/adma.200902144
Dendritic polyglycerols for biomedical applications.
M. Calderón (2010)
10.1016/j.biomaterials.2013.08.058
Cholesteryl hyaluronic acid-coated, reduced graphene oxide nanosheets for anti-cancer drug delivery.
W. Miao (2013)
10.1002/anie.201201114
Multivalency as a chemical organization and action principle.
Carlo Fasting (2012)
10.1021/acsnano.6b00168
Intraparticle Molecular Orbital Engineering of Semiconducting Polymer Nanoparticles as Amplified Theranostics for in Vivo Photoacoustic Imaging and Photothermal Therapy.
Yan Lyu (2016)
10.1021/cr300335p
Graphene: promises, facts, opportunities, and challenges in nanomedicine.
H. Y. Mao (2013)
10.1021/ja510147n
Stimuli-Responsive Nanomaterials for Biomedical Applications
Angela P. Blum (2015)
10.1002/ADFM.201504030
Conductive Screen Printing Inks by Gelation of Graphene Dispersions
Kirill A Arapov Kirill Arapov (2016)
10.1002/anie.201005075
Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells.
J. Yang (2011)
10.1002/ADFM.201802585
Highly Brilliant Noniridescent Structural Colors Enabled by Graphene Nanosheets Containing Graphene Quantum Dots
Yingxue Zhang (2018)
10.1016/J.PROGPOLYMSCI.2011.08.003
Graphene–DNA hybrid materials: Assembly, applications, and prospects
T. Premkumar (2012)
10.1002/adma.201503255
Highly Elastic and Conductive Human-Based Protein Hybrid Hydrogels.
N. Annabi (2016)
10.1002/ADFM.201001692
Simultaneous Reduction and Surface Functionalization of Graphene Oxide by Mussel‐Inspired Chemistry
S. M. Kang (2010)
10.1021/ACS.JPCC.5B08421
A Gel-Based Approach To Design Hierarchical CuS Decorated Reduced Graphene Oxide Nanosheets for Enhanced Peroxidase-like Activity Leading to Colorimetric Detection of Dopamine
S. Dutta (2015)
10.1002/ADFM.201502049
Virus-Inspired Mimics Based on Dendritic Lipopeptides for Efficient Tumor-Specific Infection and Systemic Drug Delivery
Z. Zhang (2015)
10.1002/adma.201100010
Graphene-biomineral hybrid materials.
S. Kim (2011)
10.1021/ja100938r
Toward a universal "adhesive nanosheet" for the assembly of multiple nanoparticles based on a protein-induced reduction/decoration of graphene oxide.
J. Liu (2010)
10.1016/j.biomaterials.2013.04.066
Graphene oxide mediated delivery of methylene blue for combined photodynamic and photothermal therapy.
A. Sahu (2013)
10.1021/acsnano.6b00200
Self-Powered Electrical Stimulation for Enhancing Neural Differentiation of Mesenchymal Stem Cells on Graphene-Poly(3,4-ethylenedioxythiophene) Hybrid Microfibers.
W. Guo (2016)
10.1039/B917752C
Noncovalent DNA decorations of graphene oxide and reduced graphene oxide toward water-soluble metal–carbon hybrid nanostructures via self-assembly
J. Liu (2010)
10.1039/c7cs00730b
Wearable and flexible electronics for continuous molecular monitoring.
Yiran Yang (2019)
10.1039/C2JM35379B
Porphyrin functionalized graphene nanosheets-based electrochemical aptasensor for label-free ATP detection
Hongfen Zhang (2012)
10.1039/c5cs00021a
Environmental applications of graphene-based nanomaterials.
François Perreault (2015)
10.1039/C4GC00264D
A one-pot biosynthesis of reduced graphene oxide (RGO)/bacterial cellulose (BC) nanocomposites
Avinav G. Nandgaonkar (2014)
10.1016/j.biomaterials.2015.01.053
ATP-responsive DNA-graphene hybrid nanoaggregates for anticancer drug delivery.
Ran Mo (2015)
10.1002/adma.201505326
New-Generation Graphene from Electrochemical Approaches: Production and Applications.
S. Yang (2016)
10.1039/C0JM01859G
Preparation and characterisation of covalent polymer functionalized graphene oxide
Yue Lin (2011)
10.1021/ja2010175
Ultrasmall reduced graphene oxide with high near-infrared absorbance for photothermal therapy.
J. Robinson (2011)
10.1021/ja200218y
Size fractionation of graphene oxide sheets by pH-assisted selective sedimentation.
X. Wang (2011)
10.1002/adma.201802669
Atomic Fe-Nx Coupled Open-Mesoporous Carbon Nanofibers for Efficient and Bioadaptable Oxygen Electrode in Mg-Air Batteries.
Chong Cheng (2018)
10.1002/ADFM.201100078
Water‐Soluble Poly(N‐isopropylacrylamide)–Graphene Sheets Synthesized via Click Chemistry for Drug Delivery
Y. Pan (2011)
10.1016/J.SNB.2016.01.036
Study on rolling circle amplification of Ebola virus and fluorescence detection based on graphene oxide
J. Wen (2016)
10.1002/adma.201100261
Bioinspired effective prevention of restacking in multilayered graphene films: towards the next generation of high-performance supercapacitors.
Xiaowei Yang (2011)
10.1016/J.NANTOD.2018.06.008
Nanomedicine for tumor microenvironment modulation and cancer treatment enhancement
J. Liu (2018)
10.1016/J.PROGPOLYMSCI.2014.03.001
Graphene-polymer nanocomposites for structural and functional applications
Kesong Hu (2014)
10.1016/j.biomaterials.2011.11.064
The influence of surface chemistry and size of nanoscale graphene oxide on photothermal therapy of cancer using ultra-low laser power.
K. Yang (2012)
10.1016/J.CARBON.2017.02.049
3D bioprinted graphene oxide-incorporated matrix for promoting chondrogenic differentiation of human bone marrow mesenchymal stem cells
X. Zhou (2017)
10.1002/ADFM.201702741
Straightforward Immunosensing Platform Based on Graphene Oxide-Decorated Nanopaper : A Highly Sensitive and Fast Biosensing Approach
N. Cheeveewattanagul (2017)
10.1002/smll.201503524
3D Printing of Graphene Aerogels.
Qiangqiang Zhang (2016)
10.1016/J.MATTOD.2015.04.005
Photoluminescent carbon nanodots: synthesis, physicochemical properties and analytical applications
Prathik Roy (2015)
10.1016/J.NANTOD.2018.02.010
Recent advances in functional nanomaterials for light–triggered cancer therapy
S. Gai (2018)
10.1002/adma.201104070
Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and photothermal therapy monitored in situ.
S. Hu (2012)
10.1016/J.MATTOD.2016.02.021
Graphene nano-heterostructures for quantum devices
D. Bischoff (2016)
10.1002/adma.201700707
2D Porous Carbons prepared from Layered Organic-Inorganic Hybrids and their Use as Oxygen-Reduction Electrocatalysts.
S. Li (2017)
10.1016/J.PROGPOLYMSCI.2009.03.001
Dynamic covalent polymers: Reorganizable polymers with dynamic covalent bonds
T. Maeda (2009)
10.1002/ADFM.201500365
Graphene Potentiates the Myocardial Repair Efficacy of Mesenchymal Stem Cells by Stimulating the Expression of Angiogenic Growth Factors and Gap Junction Protein
Jooyeon Park (2015)
10.1021/cr3000412
Functionalization of graphene: covalent and non-covalent approaches, derivatives and applications.
V. Georgakilas (2012)
10.1002/smll.201402648
Glowing graphene quantum dots and carbon dots: properties, syntheses, and biological applications.
X. T. Zheng (2015)
10.1016/j.biomaterials.2012.07.040
Size-dependent genotoxicity of graphene nanoplatelets in human stem cells.
O. Akhavan (2012)
10.1002/anie.201612422
Controlled Covalent Functionalization of Thermally Reduced Graphene Oxide To Generate Defined Bifunctional 2D Nanomaterials
A. Faghani (2017)
10.1016/J.CARBON.2013.09.080
Graphene oxide/hydroxyapatite composite coatings fabricated by electrophoretic nanotechnology for biological applications
M. Li (2014)
10.1021/acs.nanolett.5b02256
Multivalency at Interfaces: Supramolecular Carbohydrate-Functionalized Graphene Derivatives for Bacterial Capture, Release, and Disinfection.
Zhenhui Qi (2015)
10.1002/ADFM.201705708
Nonchemotherapic and Robust Dual‐Responsive Nanoagents with On‐Demand Bacterial Trapping, Ablation, and Release for Efficient Wound Disinfection
Y. Yang (2018)
10.1016/J.MATTOD.2015.10.002
Wrinkled, rippled and crumpled graphene: an overview of formation mechanism, electronic properties, and applications
Shikai Deng (2016)
10.1002/ADFM.201201020
Photothermally Sensitive Poly(N‐isopropylacrylamide)/Graphene Oxide Nanocomposite Hydrogels as Remote Light‐Controlled Liquid Microvalves
Chun-hua Zhu (2012)



This paper is referenced by
10.1016/j.msec.2020.110972
Bacterial attachment to oxygen-functionalized graphenic surfaces.
W. Pajerski (2020)
10.1016/j.jconrel.2019.07.016
Two dimensional carbon based nanocomposites as multimodal therapeutic and diagnostic platform: A biomedical and toxicological perspective.
Namdev L. Dhas (2019)
10.1016/j.cplett.2019.136896
Effects of chlorine adatoms on small lithium nanoclusters adsorbed on graphene
X. Song (2020)
10.22034/JTM.2020.218433.1024
Physical evaluation of 3D-printed gelatin-hydroxyapatite-reduced graphene oxide nanocomposite as a bone tissue engineering scaffold
H. Nosrati (2020)
10.1016/j.msec.2019.110282
Fabrication of regular macro-mesoporous reduced graphene aerogel beads with ultra-high mechanical property for efficient bilirubin adsorption.
Z. Li (2020)
10.1002/smll.201902522
Depriving Bacterial Adhesion-Related Molecule to Inhibit Biofilm Formation Using CeO2 -Decorated Metal-Organic Frameworks.
H. Qiu (2019)
10.1039/C9GC02266J
Graphene-based advanced nanoplatforms and biocomposites from environmentally friendly and biomimetic approaches
Lang Ma (2019)
10.1186/s40580-020-00237-4
Graphene impregnated electrospun nanofiber sensing materials: a comprehensive overview on bridging laboratory set-up to industry
Adel Mohammed Al-Dhahebi (2020)
10.3390/jnt1010002
Synthesis of Graphene Nanoribbons–Hydroxyapatite Nanocomposite Applicable in Biomedicine and Theranostics
H. Nosrati (2020)
10.1016/j.ccr.2019.213041
Emerging 2D material-based nanocarrier for cancer therapy beyond graphene
Yingwei Wang (2019)
10.1186/s13065-020-00712-3
Comparison of the effect of argon, hydrogen, and nitrogen gases on the reduced graphene oxide-hydroxyapatite nanocomposites characteristics
Hassan Nosrati (2020)
10.1039/d0tb01149e
Functionalized graphene oxide as a vehicle for targeted drug delivery and bioimaging applications.
Neha Karki (2020)
10.1016/j.cej.2020.126182
Near infrared light-triggered on-demand Cur release from Gel-PDA@Cur composite hydrogel for antibacterial wound healing
Bailong Tao (2021)
Semantic Scholar Logo Some data provided by SemanticScholar