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Prospective Study Of Type 2 Diabetes Mellitus And Risk Of Primary Open-angle Glaucoma In Women.

L. Pasquale, J. Kang, J. Manson, W. Willett, B. Rosner, S. Hankinson
Published 2006 · Medicine

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PURPOSE To study the relation between type 2 diabetes mellitus (T2DM) and incident primary open-angle glaucoma (POAG) in women. DESIGN Prospective cohort analysis. PARTICIPANTS Seventy-six thousand three hundred eighteen women enrolled in the Nurses' Health Study (NHS). METHODS Women enrolled in the NHS from 1980 to 2000 were observed. Eligible participants were at least 40 years old, did not have POAG at baseline, and reported receiving eye examinations during follow-up. Potential confounders were assessed on biennial questionnaires, and a diagnosis of T2DM was confirmed on a validated supplemental questionnaire. During follow-up, 429 self-reported POAG cases confirmed by medical chart review were identified. MAIN OUTCOME MEASURES Multivariable rate ratios (RRs) of POAG and associated 95% confidence intervals (CIs) obtained from proportional hazards models. RESULTS After controlling for age, race, hypertension, body mass index, physical activity, alcohol intake, smoking, and family history of glaucoma, T2DM was positively associated with POAG (RR = 1.82 [95% CI = 1.23-2.70]). Nonetheless, the association did not strengthen with longer duration of diabetes: RR = 2.24 (95% CI = 1.31-3.84) for duration < 5 years versus RR = 1.54 (95% CI = 0.90-2.62) for duration > or = 5 years). In secondary analyses, to evaluate the potential for detection bias we controlled for additional factors such as the number of eye examinations, but T2DM remained positively associated with POAG. CONCLUSION Type 2 diabetes mellitus is associated with an increased risk of POAG in women.
This paper references
Automated perimetric changes following panretinal photocoagulation in diabetic retinopathy.
P. Khosla (1993)
Intraocular pressure in an American community. The Beaver Dam Eye Study.
B. Klein (1992)
10.1016/S0161-6420(90)32557-5
Visual field defects in patients with insulin-dependent and noninsulin-dependent diabetes.
G. Trick (1990)
10.1016/S0021-5155(02)00666-4
Association of life-style with intraocular pressure in middle-aged and older Japanese residents.
M. Yoshida (2003)
10.1093/AJE/KWG167
Antioxidant intake and primary open-angle glaucoma: a prospective study.
J. Kang (2003)
10.1093/AJCN/79.5.755
Dietary fat consumption and primary open-angle glaucoma.
J. Kang (2004)
10.1016/S0002-9394(18)91189-X
Methods of Diagnosis
Edward Jackson (1918)
10.1016/S0168-8227(03)00082-2
Blue-on-yellow perimetry versus achromatic perimetry in type 1 diabetes patients without retinopathy.
F. Afrashi (2003)
10.2337/DIACARE.21.9.1414
Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections
H. King (1998)
10.1016/S0161-6420(95)31055-X
Diabetes, intraocular pressure, and primary open-angle glaucoma in the Baltimore Eye Survey.
J. Tielsch (1995)
10.1016/0002-9394(71)91088-9
Diabetes mellitus and primary open-angle glaucoma. The XXVII Edward Jackson Memorial Lecture.
B. Becker (1971)
10.2307/2530888
Analysis of Survival Data.
N. Breslow (1984)
10.1016/S0161-6420(97)30247-4
Open-angle glaucoma and diabetes: the Blue Mountains eye study, Australia.
P. Mitchell (1997)
10.1016/S0895-4356(00)00291-2
Risk factors for open-angle glaucoma: a case-control study.
D. Kaimbo (2001)
10.1093/OXFORDJOURNALS.AJE.A115686
Weight as a risk factor for clinical diabetes in women.
G. Colditz (1990)
10.3341/KJO.1992.6.2.91
Glaucoma risk factors in primary open-angle glaucoma patients compared to ocular hypertensives and control subjects.
K. Uhm (1992)
10.1016/J.OPHTHA.2004.05.024
Impact of diabetes on glaucoma screening using frequency-doubling perimetry.
T. Realini (2004)
10.1056/NEJMOA010492
Diet, lifestyle, and the risk of type 2 diabetes mellitus in women.
F. Hu (2001)
10.3109/09286589409047221
Genetic risk factor in primary open-angle glaucoma: a case-control study.
G. Charliat (1994)
10.1136/bjo.84.11.1218
Glaucoma incidence in an unselected cohort of diabetic patients: is diabetes mellitus a risk factor for glaucoma?
J. Ellis (2000)
10.1016/S0161-6420(96)30511-3
Primary open-angle glaucoma, intraocular pressure, and diabetes mellitus in the general elderly population. The Rotterdam Study.
I. Dielemans (1996)
10.7326/0003-4819-122-7-199504010-00001
Weight Gain as a Risk Factor for Clinical Diabetes Mellitus in Women
G. Colditz (1995)
10.1111/j.1464-5491.2004.01173.x
Diabetes mellitus as a risk factor for primary open‐angle glaucoma: a meta‐analysis
S. Bonovas (2004)
10.1093/IJE/29.4.661
Relationship between intraocular pressure and obesity in Japan.
K. Mori (2000)
10.1001/ARCHOPHT.1987.01060080068030
A case-control study of risk factors in open angle glaucoma.
M. Wilson (1987)
10.2337/diacare.25.2007.s5
Report of the expert committee on the diagnosis and classification of diabetes mellitus.
J. Gavin (2003)
10.1002/dmrr.529
Elevated intraocular pressure is associated with insulin resistance and metabolic syndrome
S. W. Oh (2005)
10.1056/NEJMOA021423
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults.
E. Calle (2003)
10.1038/eye.1994.64
The African Caribbean eye survey: Risk factors for glaucoma in a sample of African Caribbean people living in London
R. Wormald (1994)
10.1002/(SICI)1096-9136(199712)14:5+3.3.CO;2-I
The Rising Global Burden of Diabetes and its Complications: Estimates and Projections to the Year 2010
A. F. Amos (1997)
10.1016/J.OPHTHA.2004.10.046
Long-term physiologic changes of intraocular pressure: a 10-year longitudinal analysis in young and middle-aged Japanese men.
Tadashi Nakano (2005)
10.1016/S0161-6420(99)90417-7
Age-related changes in intraocular pressure in a large Japanese population: a cross-sectional and longitudinal study.
H. Nomura (1999)
10.3341/KJO.2002.16.1.13
Relationship between intraocular pressure and systemic health parameters in the Korean population.
J. Lee (2002)
10.1093/OXFORDJOURNALS.AJE.A113634
Intraocular pressure, cardiovascular risk variables, and visual field defects.
M. C. Leske (1983)
10.1016/0140-6736(91)90664-B
Physical activity and incidence of non-insulin-dependent diabetes mellitus in women
J. Manson (1991)
10.1076/ceyr.28.1.47.23487
Diabetes has an additive effect on neural apoptosis in rat retina with chronically elevated intraocular pressure
A. Kanamori (2004)
10.1097/00061198-199400320-00001
The ocular hypertension treatment study.
M. Kass (1994)
Effect of high glucose on fibronectin expression and cell proliferation in trabecular meshwork cells.
T. Sato (2002)
10.1001/ARCHOPHT.119.12.1819
The prevalence of glaucoma in a population-based study of Hispanic subjects: Proyecto VER.
H. Quigley (2001)
10.1111/j.1755-3768.1994.tb07181.x
The effect of panretinal laser photocoagulation on visual acuity, visual fields and on subjective visual impairment in preproliferative and early proliferative diabetic retinopathy
M. Henricsson (1994)
10.1001/ARCHOPHT.1997.01100160742012
Associations with intraocular pressure in the Barbados Eye Study.
S. Wu (1997)
10.1001/ARCHOPHT.120.6.714
The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma.
M. Gordon (2002)
10.1001/ARCHOPHT.123.3.381
Intraocular pressure measured with a noncontact tonometer in an elderly Chinese population: the Shihpai Eye Study.
H. Lin (2005)
10.1016/S0749-3797(18)31205-4
Risk factors for primary open angle glaucoma.
J. Katz (1988)
10.1097/00061198-199902000-00004
Body mass index in glaucoma.
P. Gasser (1999)
10.1016/S0161-6420(94)31191-2
Open-angle glaucoma and older-onset diabetes. The Beaver Dam Eye Study.
B. Klein (1994)
10.1016/J.EXER.2004.08.006
Ocular structure and function in an aged monkey with spontaneous diabetes mellitus.
M. Johnson (2005)
10.1016/S0161-6420(03)00075-7
Hypertension, diabetes, and longitudinal changes in intraocular pressure.
A. Hennis (2003)



This paper is referenced by
10.4103/0974-620X.149858
Magnitude and determinants of glaucoma in type II diabetics: A hospital based cross-sectional study in Maharashtra, India
Sheetal Dharmadhikari (2015)
10.1136/bmjopen-2015-010360
Evaluation of the associations between changes in intraocular pressure and metabolic syndrome parameters: a retrospective cohort study in Japan
H. Yokomichi (2016)
Validación de la historia clínica informatizada de atención primaria y su aplicación para la investigación clínico-epidemiológica de la hipertensión arterial en una cohorte de pacientes con diabetes tipo 2
Burgos Lunar (2012)
10.1371/journal.pone.0112460
Diabetes, Glucose Metabolism, and Glaucoma: The 2005–2008 National Health and Nutrition Examination Survey
D. Zhao (2014)
10.1002/SIM.6061
Functional analysis of glaucoma data.
Mohammad Hosseini-Nasab (2014)
10.1097/IJG.0b013e3181e3d483
The Relationship Between Diabetes Mellitus and Exfoliation Syndrome in a United States Veterans Affairs Population: A Case-control Study
S. D. Wood (2011)
10.1097/ICU.0b013e328331903c
Ophthalmic manifestations of endocrine disorders: approaches and medical management
A. Hendrick (2009)
10.1016/J.OPHTHA.2007.04.049
Type 2 diabetes mellitus and the risk of open-angle glaucoma the Los Angeles Latino Eye Study.
V. Chopra (2008)
10.2217/BMM-2016-0167
Low-level expression of SOD1 in peripheral blood samples of patients diagnosed with primary open-angle glaucoma.
Licelly Canizales (2016)
10.1007/s10792-013-9737-3
Prevalence of diabetes mellitus and hypertension among Indian glaucoma patients and evaluation of systemic therapy
Abhishek Dave (2013)
An investigation of genetic risk factors in primary open-angle glaucoma
S. Park (2009)
10.1016/j.diabres.2016.01.016
Metabolic syndrome and eye diseases.
S. Poh (2016)
10.1016/S0181-5512(08)75460-3
Dépistage itinérant du glaucome associé à celui de la rétinopathie diabétique en Bourgogne
J. Beynat (2008)
Census of Alabama Eye Care Providers
P. MacLennan (2012)
A study of case finding for chronic open angle glaucoma by UK community optometrists
Joy Myint (2013)
10.1111/aos.13805
Increased risk of open‐angle glaucoma among patients with diabetes mellitus: a 10‐year follow‐up nationwide cohort study
T. H. Rim (2018)
10.1167/tvst.9.12.22
Inter-Eye Association of Visual Field Defects in Glaucoma and Its Clinical Utility
Bettina Teng (2020)
10.1016/j.ophtha.2019.12.004
Artificial Intelligence Classification of Central Visual Field Patterns in Glaucoma.
Mengyu Wang (2019)
10.31782/ijcrr.2020.122218
Association of Type 2 Diabetes Mellitus with Central Corneal Thickness and Intraocular Pressure – A Case Control Study
K. Kalaivani (2020)
Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: part 4: observational studies.
L. Manchikanti (2009)
10.7326/0003-4819-147-8-200710160-00010-w1
Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration
J. Vandenbroucke (2007)
10.1097/01.NAJ.0000345434.37734.ee
Primary open-angle glaucoma.
N. Sharts-Hopko (2009)
10.7555/JBR.30.20140075
Manifestations of type 2 diabetes in corneal endothelial cell density, corneal thickness and intraocular pressure
Stella Briggs (2015)
10.4103/0974-9233.186097
Lack of Correlation Between Diabetic Macular Edema and Thickness of the Peripapillary Retinal Nerve Fibre Layer
H. Alkuraya (2016)
10.1016/S0027-9684(15)30314-X
Predicting glaucoma diagnosis in an elderly sample: revisiting the established populations for epidemiologic studies of the elderly.
D. Howard (2011)
The ophthalmic study guide for nurses and health professionals Dorothy Field The ophthalmic study guide for nurses and health professionals , Julie Tillotson and Mandy Macfarlane M&K Publishing 224pp £39 978 1 905539 40 6 9781905539406 [Formula: see text].
D. Field (2010)
10.1016/j.mrgentox.2010.02.003
Reactive oxygen species promote localized DNA damage in glaucoma-iris tissues of elderly patients vulnerable to diabetic injury.
J. Szaflik (2010)
10.2147/DMSO.S160978
Severity of primary open-angle glaucoma in patients with hypertension and diabetes
Anadi Khatri (2018)
Tip 2 Diabetes Mellituslu Hastalarda Santral Kornea Kalınlığı
Fatih Aydin (2007)
Retinal Haemodynamics in Primary Open Angle Glaucoma Patients with Differing Nocturnal Blood Pressure Profiles
Firdaus Yusof Alias (2014)
Risk factors and long term progression in open angle glaucoma patients.
A. Pantalon (2016)
10.1038/s41598-017-11365-z
Prevalence and causes of low vision and blindness in a Chinese population with type 2 diabetes: the Dongguan Eye Study
Ying Cui (2017)
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