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Lung Cancer And Related Risk Factors: An Update Of The Literature.

A. Ruano-Raviña, A. Figueiras, J. Barros-Dios
Published 2003 · Medicine

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At the present time, lung cancer is the leading cause of cancer-related death in males. Diagnostic difficulty makes detection complicated and this, in conjunction with the low survival rate, renders the disease a serious health problem. In-depth knowledge of associated risk factors is therefore called for, in order to prevent or at least reduce the appearance of lung cancer and to open new avenues of research. Although the disease has a multicausal aetiology, tobacco accounts for 85-90% of all cases. This paper reviews the current situation, dividing the risk factors, for study purposes, into two groups; intrinsic (non-modifiable) and extrinsic (modifiable).
This paper references
A molecular epidemiological case-control study of lung cancer.
D. Tang (1995)
10.1136/jech.44.2.114
A case-control study of lung cancer with special reference to the effect of air pollution in Poland.
W. Jędrychowski (1990)
10.1093/CARCIN/19.8.1329
The role of ethnicity in cancer susceptibility gene polymorphisms: the example of CYP1A1.
S. Garte (1998)
10.1023/A:1018465507029
Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons
P. Boffetta (2004)
10.1097/00001648-199909000-00005
Lung cancer and indoor air pollution arising from Chinese-style cooking among nonsmoking women living in Shanghai, China.
L. Zhong (1999)
10.1002/1097-0142(20001201)89:11+<2474::AID-CNCR26>3.0.CO;2-2
Early lung cancer action project
C. Henschke (2000)
10.1097/00001648-199511000-00010
Meta-analysis of studies of lung cancer among silicotics.
A. Smith (1995)
10.1016/0169-5002(94)90751-x
Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population.
K. Nakachi (1993)
Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility.
T. Rebbeck (1997)
10.1093/IJE/22.4.592
Race and sex differences in lung cancer risk associated with cigarette smoking.
R. Harris (1993)
10.5271/SJWEH.376
Work-related cancer in the Nordic countries.
A. Andersen (1999)
10.1097/00008571-199404000-00002
Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: possible relevance to low smoking exposure.
F. Uematsu (1994)
10.1136/oem.57.1.10
Occupational exposure to carcinogens in the European Union
T. Kauppinen (2000)
10.1016/0169-5002(95)96291-3
Analysis of cytochrome P450 2E1 genetic polymorphisms in relation to human lung cancer.
S. Kato (1994)
Lung cancer in women: the importance of smoking, family history of cancer, and medical history of respiratory disease.
K. E. Osann (1991)
10.1016/S0169-5002(96)90211-1
Estimating the effect of dietary fat on the risk of lung cancer in nonsmoking women.
M. Alavanja (1996)
10.1002/IJC.2910590411
At least one in seven cases of cancer is caused by smoking. Global estimates for 1985
D. Parkin (1994)
10.1093/IJE/26.2.256
Family history of cancer and risk of lung cancer in lifetime non-smokers and long-term ex-smokers.
R. Brownson (1997)
A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.
P. Fernandez-Salguero (1995)
Host factors in lung cancer risk: a review of interdisciplinary studies.
C. Amos (1992)
A population-based case-control study on fruit and vegetable intake and lung cancer: a paradox effect? Nutr Cancer 2002;43:47—51
A Ruano-Ravina (2002)
10.1023/A:1008906706084
Vegetable and fruit consumption and lung cancer risk in the Netherlands Cohort Study on Diet and Cancer
L. Voorrips (2004)
Procarcinogenic and anticarcinogenic effects of beta-carotene.
X. Wang (1999)
10.1016/S0140-6736(94)90818-4
p53 mutation hotspot in radon-associated lung cancer
J. Taylor (1994)
10.1002/AJIM.4700170606
Smoking patterns by occupation and duration of employment.
L. Levin (1990)
10.1093/OXFORDJOURNALS.AJE.A008783
Family history of cancer and risk of lung cancer among lifetime nonsmoking women in the United States.
A. Wu (1996)
10.1093/JNCI/86.18.1398
Biomarkers of environmental tobacco smoke in preschool children and their mothers.
F. Crawford (1994)
10.1038/19655
Co-carcinogenic effect of β-carotene
M. Paolini (1999)
10.1056/NEJM199605023341802
Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease.
G. Omenn (1996)
Dietary fats and lung cancer risk among women: the Missouri Women’s Health Study (United States). Cancer Causes Control 1997;8:883—93
CA Swanson (1997)
10.2307/3434125
Long-Term Concentrations of Ambient Air Pollutants and Incident Lung Cancer in California Adults: Results from the AHSMOG Study
W. L. Beeson (1998)
10.1378/chest.123.1_suppl.21s
Epidemiology of lung cancer.
A. Alberg (2003)
10.1016/S1383-5718(99)00092-3
Polymorphisms of the GSTM1 and CYP2D6 genes associated with susceptibility to lung cancer in Chinese.
Y. Gao (1999)
10.1093/JNCI/88.3-4.183
Differences in lung cancer risk between men and women: examination of the evidence.
E. Zang (1996)
Effects of watercress consumption on metabolism of a tobacco-specific lung carcinogen in smokers.
S. Hecht (1995)
10.1056/NEJM199605023341801
Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease.
C. Hennekens (1996)
Differences in the urinary metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in black and white smokers.
J. Richie (1997)
10.1093/OXFORDJOURNALS.AJE.A008965
Familial risk of lung cancer among nonsmokers and their relatives.
A. Schwartz (1996)
in non - smoking women
CA Swanson (1996)
10.1093/JNCI/88.9.612
Importance of α-Carotene, β-Carotene, and Other Phytochemicals in the Etiology of Lung Cancer
R. Ziegler (1996)
10.1023/A:1018424614723
Dietary fat and lung cancer: a case-control study in Uruguay
E. de Stefani (2004)
10.1177/030089169207800419
Libri Ricevuti: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
T. Dragani (1992)
A case-control study of genetic susceptibility and risk factors of lung cancer
A. Ruano Raviña (2001)
10.1093/CARCIN/19.4.703
Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis by dietary olive oil and squalene.
T. J. Smith (1998)
10.1093/JNCI/91.14.1194
Tobacco smoke carcinogens and lung cancer.
S. Hecht (1999)
10.1093/AJE/KWF070
Exposure to residential radon and lung cancer in Spain: a population-based case-control study.
J. Barros-Dios (2002)
on the evaluation of the carcinogenic risks to humans
IARC. Monograph (1995)
10.1093/OXFORDJOURNALS.EPIREV.A017982
Epidemiology and prevention of lung cancer in nonsmokers.
R. Brownson (1998)
Estimation of the burden of occupational cancer in Spain. Research Project funded by the Health Research Fund (Exp 97/1105E) and the Europe Against Cancer Programme (SOC 96-2007420 sf02)
M. Kogevinas (1998)
10.1164/ARRD.1986.134.3.466
Personal and family history of respiratory disease and lung cancer risk.
J. Samet (1986)
10.1093/CARCIN/17.5.1021
Environmental air pollution and DNA adducts in Copenhagen bus drivers--effect of GSTM1 and NAT2 genotypes on adduct levels.
P. S. Nielsen (1996)
10.1093/JNCI/70.6.1033
Dark tobacco and lung cancer in Cuba.
O. G. Joly (1983)
10.1093/OXFORDJOURNALS.AJE.A009258
Intake of vitamins E, C, and A and risk of lung cancer. The NHANES I epidemiologic followup study. First National Health and Nutrition Examination Survey.
L. Yong (1997)
10.1179/OEH.1998.4.4.236
A standard tool for the analysis of occupational lung cancer in epidemiologic studies.
W. Ahrens (1998)
10.1007/978-3-642-85851-2
Cancer Incidence in Five Continents
Freddie Ian Bray (1970)
10.1097/00008469-200012000-00004
Diet and lung cancer: a new approach
A. Ruano-Raviña (2000)
Cancer Epidemiology and Prevention, 2nd ed
JA Baron (1996)
10.1097/00008571-199612000-00006
Lung cancer risk in relation to the CYP2C9*1/CYP2C9*2 genetic polymorphism among African-Americans and Caucasians in Los Angeles County, California.
S. London (1996)
10.1080/009841097160393
The changing cigarette, 1950-1995.
D. Hoffmann (1997)
10.1289/EHP.95103S8143
The changing epidemiology of smoking and lung cancer histology.
E. Wynder (1995)
10.1016/1047-2797(94)90054-X
The epidemiology of lung cancer in women.
V. Ernster (1994)
10.1093/OXFORDJOURNALS.AJE.A117254
Invited commentary: lung cancer and exposure to residential radon.
J. Lubin (1994)
10.1006/PMED.1997.0183
The changing cigarette.
D. Hoffmann (1997)
10.1023/A:1018405321141
Industries and cancer
E. Ward (2004)
10.1016/0091-7435(91)90026-Z
A case-control study of air pollution and tobacco smoking in lung cancer among women in Athens.
K. Katsouyanni (1991)
10.1093/CARCIN/14.7.1479
The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung.
A. Hirvonen (1993)
10.1001/JAMA.287.9.1132
Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution.
C. Pope (2002)
10.1097/00001648-200203000-00022
Noxious exposures in leisure time and risk of lung cancer: a neglected exposure?
A. Ruano-Raviña (2002)
10.1056/NEJM199401203300302
Residential radon exposure and lung cancer in Sweden.
G. Pershagen (1994)
10.1016/0022-4375(94)90061-2
Environmental Tobacco Smoke and Lung Cancer in Nonsmoking Women: A Multicenter Study
Igor Sartori (1996)
The etiology of
D Xu-Dong (1995)
10.1056/nejm199404143301501
The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers.
O. Heinonen (1994)
10.1016/S0025-7125(05)70427-2
Early detection in lung cancer. Case finding and screening.
D. Wolpaw (1996)
10.1136/JCP.33.1.98-B
IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
R. Carter (1979)
10.1097/00004032-199811000-00008
Radon reduction systems in the construction of new houses in Gainesville, Florida.
F. Najafi (1998)
10.1016/S0213-9111(99)71368-3
Tabaquismo en adolescentes. Prevalencia estimada mediante declaración y cotinina sérica
A. León (1999)
Cancer incidence, mortality and prevalence worldwide, version 1.0
J Ferlay (2000)
10.1001/JAMA.1995.03520310011007
Environmental Tobacco Smoke and Lung Cancer in Nonsmoking Women
E. Fontham (1995)
Cancer Epidemiology and Prevention, 2nd ed
CS Muir (1996)
10.1136/bmj.312.7041.1259
Lung cancer, smoking, and environment: a cohort study of the Danish population
G. Engholm (1996)
10.1093/CARCIN/18.8.1529
Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) polymorphisms and lung cancer risk among Northwestern Mediterraneans.
J. To-Figueras (1997)
10.1016/0140-6736(92)90866-2
Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners
K. Vahakangas (1992)
10.1016/S0169-5002(96)90213-5
The etiology of lung cancer in nonsmoking females in Harbin, China.
X. Dai (1996)
Dietary fat and lung cancer: a case-control study in Uruguay. Cancer Causes Control 1997;8:913—21
E De Stefani (1997)
10.1207/S15327914NC431_5
A Population-Based Case-Control Study on Fruit and Vegetable Intake and Lung Cancer: A Paradox Effect?
A. Ruano-Raviña (2002)
10.1023/A:1018468429744
Dietary fats and lung cancer risk among women: the Missouri Women's Health Study (United States)
C. Swanson (2004)
10.1097/00001648-199807001-00272
LONG-TERM AMBIENT CONCENTRATIONS OF SELECTED AIR POLLUTANTS AND INCIDENT MALIGNANT NEOPLASMS IN CALIFORNIA ADULTS: RESULTS FROM THE AHSMOG STUDY
W. L. Beeson (1998)
10.1093/OXFORDJOURNALS.AJE.A114336
Carotenoid intake, vegetables, and the risk of lung cancer among white men in New Jersey.
R. Ziegler (1986)
10.1097/00008469-199908000-00008
GSTM1, GSTP1, CYP1A1 and CYP2D6 polymorphisms in lung cancer patients from an environmentally polluted region of Poland: correlation with lung DNA adduct levels.
D. Butkiewicz (1999)
10.1007/BF00115646
Nutrition and lung cancer
R. Ziegler (2004)
10.1023/A:1018492818416
Ambient air pollution exposure and cancer
K. Katsouyanni (2004)
10.1378/CHEST.96.1_SUPPLEMENT.17S
Genetic events in the pathogenesis of lung cancer.
J. Minna (1989)
10.1289/EHP.96104750
Air pollution and lung cancer in Trieste, Italy: spatial analysis of risk as a function of distance from sources.
A. Biggeri (1996)
10.1002/(SICI)1097-0215(19970529)71:5<760::AID-IJC12>3.0.CO;2-C
Fatty foods and the risk of lung cancer: A case‐control study from Uruguay
E. de Stefani (1997)
Lung cancer and related risk factors : an update of the literature
A. Ruano-Ravinaa (2003)
10.1023/A:1018417623867
Reactive chemicals and cancer.
A. Blair (1997)



This paper is referenced by
Urban vs. rural patients. Differences in stage and overall survival among patients treated surgically for lung cancer.
P. Rybojad (2013)
10.1016/j.ejca.2013.02.025
Diabetes mellitus as an independent risk factor for lung cancer: a meta-analysis of observational studies.
Jung-Yun Lee (2013)
10.1016/j.cllc.2011.10.002
Antidiabetes drugs correlate with decreased risk of lung cancer: a population-based observation in Taiwan.
S. Lai (2012)
10.1097/00005217-199916010-00016
CONTINUING EDUCATION CREDIT
Thomas Berk (2008)
10.1016/j.envpol.2019.01.083
Geolocation of premises subject to radon risk: Methodological proposal and case study in Madrid.
B. Frutos (2019)
10.1016/J.YPMED.2004.05.011
Effect of smoking on hearing loss: quality assessment and meta-analysis.
Kyoko Nomura (2005)
Consommation alimentaire d’antioxydants et risque de cancer du poumon : une étude cas-témoins montréalaise
M. Shareck (2009)
Inflammation enhanced colon cancer & natural anti-cancer plant compounds
Shannon M. Butler (2011)
Lung cancer and related risk factors : an update of the literature
A. Ruano-Ravinaa (2003)
10.1016/j.jenvrad.2020.106420
A full-scale experimental study of sub-slab pressure fields induced by underground perforated pipes as a soil depressurisation technique in radon mitigation.
B. Frutos (2020)
10.1016/j.medcli.2018.06.026
Metformin improves survival in lung cancer patients with type 2 diabetes mellitus: A meta-analysis.
S. Zeng (2019)
10.1375/JSC.6.1.45
Smoking Cessation Practices of Dental Care Providers in Eastern Province of Saudi Arabia
Ahmad E Subaie (2011)
Surgical treatment of T3 and T4 non-small cell lung cancer
C. Pitz (2004)
10.12659/PJR.890103
The assessment of the role of baseline low-dose CT scan in patients at high risk of lung cancer
Katarzyna Kołaczyk (2014)
10.7282/T3W9576R
INHIBITION OF LUNG TUMORIGENESIS AND CANCER CELL GROWTH BY EGCG AND OTHER CHEMOPREVENTIVE AGENTS by
Huanyu Jin (2013)
10.1016/j.lungcan.2014.09.012
Metformin decreases lung cancer risk in diabetic patients in a dose-dependent manner.
Ming-Ju Tsai (2014)
10.1016/J.ARBR.2012.08.004
Exposure to Residential Radon and Lung Cancer in Never-smokers: The Preliminary Results of the LCRINS Study
A. Ruano-Raviña (2012)
DIETA Y CÁNCER DE PULMÓN EN EL ÁREA SANITARIA DE SANTIAGO DE COMPOSTELA
M. Física (2005)
New malignancies among cancer survivors: SEER Cancer Registries, 1973-2000.
R. Curtis (2006)
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