Online citations, reference lists, and bibliographies.
← Back to Search

Rapid And Efficient Synthesis Of Peptide Fragments Containing α-aminoisobutyric Acid Using Fmoc-amino Acid Chlorides/potassium Salt Of 1-hydroxybenzotriazole

V. V. S. Babu, H. Gopi
Published 1998 · Chemistry

Save to my Library
Download PDF
Analyze on Scholarcy
The synthesis of peptides containing multiple Aib residues was accomplished using Fmoc-Aib-Cl in presence of KOBt. As no additional base was added, the duration of coupling reactions could be extended. Thus, the synthesis of the alamethicin 1-4 fragment, Aib-Pro-Aib-Ala, the emerimicin 2- 6 fragment, Aib-Aib-Aib-Val-Gly and the Aib tetramer, Fmoc-(Aib)4-OBzl were accomplished in good yield and purity.
This paper references

This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar