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Intracellular Uptake Of Anionic Superparamagnetic Nanoparticles As A Function Of Their Surface Coating.

C. Wilhelm, C. Billotey, J. Roger, J. N. Pons, J. Bacri, F. Gazeau
Published 2003 · Medicine, Materials Science

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A new class of superparamagnetic nanoparticles bearing negative surface charges is presented. These anionic nanoparticles show a high affinity for the cell membrane and, as a consequence, are captured by cells with an efficiency three orders of magnitude higher than the widely used dextran-coated iron oxide nanoparticles. The surface coating of anionic particle with albumin strongly reduces the non specific interactions with the plasma membrane as well as the overall cell uptake and at the same time restores the ability to induce specific interactions with targeted cells by the coadsorption on the particle surface of a specific ligand. Kinetics of cellular particle uptake for different cell lines are quantitated using two new complementary assays (Magnetophoresis and Electron Spin Resonance).
This paper references
10.1038/sj.cgt.7700357
Heat-inducible TNF-α gene therapy combined with hyperthermia using magnetic nanoparticles as a novel tumor-targeted therapy
A. Ito (2001)
10.1111/j.1349-7006.2001.tb01070.x
Targeting Hyperthermia for Renal Cell Carcinoma Using Human MN Antigenspecific Magnetoliposomes
M. Shinkai (2001)
10.2144/99262RR04
Organelle isolation by magnetic immunoabsorption.
A. Kausch (1999)
10.1042/BJ3380123
Purification of intracellular compartments involved in antigen processing: a new method based on magnetic sorting.
L. A. Perrin-Cocon (1999)
10.1021/BI00054A021
Quantitative analysis of liposome-cell interactions in vitro: rate constants of binding and endocytosis with suspension and adherent J774 cells and human monocytes.
K. Lee (1993)
10.1016/S0022-1759(01)00433-1
Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles.
C. H. Dodd (2001)
10.1109/TMAG.1981.1061188
Preparation of aqueous magnetic liquids in alkaline and acidic media
R. Massart (1981)
10.1016/S0304-8853(99)00156-0
Magnetic resonance of nanoparticles in a ferrofluid: evidence of thermofluctuational effects
F. Gazeau (1999)
10.1007/S100510050512
Static magneto-optical birefringence of size-sorted γ-Fe2O3 nanoparticles
E. Hasmonay (1998)
10.1097/00004424-199510000-00006
Cellular Uptake and Trafficking of a Prototypical Magnetic Iron Oxide Label In Vitro
E. Schulze (1995)
10.1016/S0006-3495(99)77182-1
Detection of single mammalian cells by high-resolution magnetic resonance imaging.
S. J. Dodd (1999)
10.1148/RADIOLOGY.214.2.R00FE19568
Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model.
A. Moore (2000)
10.1021/BC980125H
High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates.
L. Josephson (1999)
10.1006/JCIS.1997.5125
Thiolation of Maghemite Nanoparticles by Dimercaptosuccinic Acid
Fauconnier (1997)
10.1002/jlb.44.1.17
Surface Charge of Macrophages and Their Interaction With Charged Particles
S. Mutsaers (1988)
10.1016/S0142-9612(01)00267-8
Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake.
Y. Zhang (2002)
10.1002/MRM.1910290504
Monocrystalline iron oxide nanocompounds (MION): Physicochemical properties
T. Shen (1993)
10.1038/74464
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
M. Lewin (2000)
10.1083/JCB.77.3.R35
Recovery of surface membrane in anterior pituitary cells. Variations in traffic detected with anionic and cationic ferritin
M. Farquhar (1978)
10.1002/mrm.10110
MRI of insulitis in autoimmune diabetes
A. Moore (2002)
10.1073/PNAS.96.26.15256
Neurotransplantation of magnetically labeled oligodendrocyte progenitors: magnetic resonance tracking of cell migration and myelination.
J. Bulte (1999)
10.1038/nbt1201-1141
Magnetodendrimers allow endosomal magnetic labeling and in vivo tracking of stem cells
J. Bulte (2001)
10.1021/BC000079X
Improvement of MRI probes to allow efficient detection of gene expression.
D. Högemann (2000)
Magnetic fluids and applications handbook
B. M. Berkovskiĭ (1996)
10.1016/0730-725X(95)00024-B
Physical and chemical properties of superparamagnetic iron oxide MR contrast agents: ferumoxides, ferumoxtran, ferumoxsil.
C. W. Jung (1995)
10.1021/LA000053U
Liquid−Gas Transitions in Charged Colloidal Dispersions: Small-Angle Neutron Scattering Coupled with Phase Diagrams of Magnetic Fluids
E. Dubois (2000)
10.1021/BI980096Y
Liposome-cell interactions in vitro: effect of liposome surface charge on the binding and endocytosis of conventional and sterically stabilized liposomes.
C. R. Miller (1998)
10.1083/JCB.100.2.606
Anionized and cationized hemeundecapeptides as probes for cell surface charge and permeability studies: differentiated labeling of endothelial plasmalemmal vesicles
N. Ghinea (1985)
10.1002/mrm.10418
Cell internalization of anionic maghemite nanoparticles: Quantitative effect on magnetic resonance imaging
C. Billotey (2003)
10.1007/s00249-001-0200-4
Magnetophoresis and ferromagnetic resonance of magnetically labeled cells
C. Wilhelm (2002)
10.1021/BC000018Z
High-generation polycationic dendrimers are unusually effective at disrupting anionic vesicles: membrane bending model.
Z. Zhang (2000)
10.1002/JMRI.1880070629
Uptake of dextran‐coated monocrystalline iron oxides in tumor cells and macrophages
A. Moore (1997)
10.1103/PHYSREVE.65.031404
Binding of biological effectors on magnetic nanoparticles measured by a magnetically induced transient birefringence experiment.
C. Wilhelm (2002)
10.1038/73219
In vivo magnetic resonance imaging of transgene expression
R. Weissleder (2000)
10.1016/0730-725X(95)00023-A
Surface properties of superparamagnetic iron oxide MR contrast agents: ferumoxides, ferumoxtran, ferumoxsil.
C. W. Jung (1995)



This paper is referenced by
10.1161/ATVBAHA.108.165514
Iron oxide particles for atheroma imaging.
T. Tang (2009)
10.1080/02656730410001726956
Transient solution to the bioheat equation and optimization for magnetic fluid hyperthermia treatment
H. Bagaria (2005)
10.1201/B11760-19
Nanomagnetic Gene Transfection
Nguyen Tk Thanh (2012)
10.1016/J.MSEC.2011.11.010
Studies of the magnetic field intensity on the synthesis of chitosan-coated magnetite nanocomposites by co-precipitation method
W. Zhang (2012)
Applications of magnetic particles for oligodendrocyte precursor cell transplantation strategies
Stuart I Jenkins (2013)
10.1161/ATVBAHA.108.165514
Iron oxide particles for atheroma imaging.
Tjun Yip Tang (2009)
10.3109/1061186X.2010.542243
Thiolated polyacrylic acid-modified iron oxide nanoparticles for in vitro labeling and MRI of stem cells
A. Vetter (2011)
10.1902/JOP.2006.050064
Phenotypic study of human gingival fibroblasts labeled with superparamagnetic anionic nanoparticles.
A. Naveau (2006)
10.1088/0957-4484/20/40/405102
Superparamagnetic magnetite nanocrystal clusters: a sensitive tool for MR cellular imaging.
Fenghua Xu (2009)
10.1007/978-3-540-77496-9_13
Noninvasive cell tracking.
F. Kiessling (2008)
10.1021/jp304630q
Nanoparticle surface charge mediates the cellular receptors used by protein-nanoparticle complexes.
C. Fleischer (2012)
10.1016/J.NUCLCARD.2004.09.002
Magnetic resonance molecular imaging with nanoparticles
G. Lanza (2004)
Nanoparticles delivery to cancer: Approaches and limitation
H. Tamam (2019)
Multimodal characterization of superparamagnetic particles of iron oxide for inflammation imaging : application to experimental cerebral ischemia
M. Marinescu (2012)
10.3390/ma4040703
Efficacy and Durability in Direct Labeling of Mesenchymal Stem Cells Using Ultrasmall Superparamagnetic Iron Oxide Nanoparticles with Organosilica, Dextran, and PEG Coatings
Y. Wang (2011)
10.1039/C1JM11172H
A facile method to synthesize superparamagnetic and up-conversion luminescent NaYF4:Yb, Er/Tm@SiO2@Fe3O4 nanocomposite particles and their bioapplication
D. Hu (2011)
10.1016/j.aquatox.2018.04.011
Cytotoxicity of CeO2 nanoparticles using in vitro assay with Mytilus galloprovincialis hemocytes: Relevance of zeta potential, shape and biocorona formation.
M. Sendra (2018)
10.33549/PHYSIOLRES.933426
Carbohydrate-modified magnetic nanoparticles for radical scavenging.
M. Moskvin (2016)
10.1007/S12668-012-0043-8
Transmission Near-Field Scanning Optical Microscopy Investigation on Cellular Uptake Behavior of Iron Oxide Nanoparticles
Y. Zhang (2012)
10.1186/1743-8977-10-56
Altered characteristics of silica nanoparticles in bovine and human serum: the importance of nanomaterial characterization prior to its toxicological evaluation
Emilia Izak-Nau (2013)
10.1016/J.BIOMATERIALS.2005.12.022
Uptake of functionalized, fluorescent-labeled polymeric particles in different cell lines and stem cells.
M. Lorenz (2006)
10.1016/j.actbio.2011.07.033
Criteria impacting the cellular uptake of nanoparticles: a study emphasizing polymer type and surfactant effects.
A. Musyanovych (2011)
10.1039/C2SM25861G
Synthesis and characterization of pH-sensitive poly(N-2-hydroxyethyl acrylamide)–acrylic acid (poly(HEAA/AA)) nanogels with antifouling protection for controlled release
C. Zhao (2012)
10.1016/S0066-4103(04)55005-6
Microscopy in magnetic resonance imaging
P. Narasimhan (2005)
10.1007/s12013-012-9367-9
Oxidative Stress and Dermal Toxicity of Iron Oxide Nanoparticles In Vitro
A. Murray (2012)
10.1016/j.biomaterials.2011.01.042
In vivo magnetic resonance imaging of cell tropism, trafficking mechanism, and therapeutic impact of human mesenchymal stem cells in a murine glioma model.
Li-Ying Chien (2011)
10.1016/j.ijpharm.2011.07.017
Insights into the mechanism of magnetofection using MNPs-PEI/pDNA/free PEI magnetofectins.
Yongjie Ma (2011)
DESENVOLVIMENTO DE NANOPARTÍCULAS DE PLA E PLA-PEG PARA ADMINISTRAÇÃO INTRANASAL DE ZIDOVUDINA
R. Mainardes (2007)
10.1002/9783527610419.NTLS0001
Biofunctionalization of Fluorescent Nanoparticles
M. Murcia (2007)
10.1016/j.watres.2020.116216
The dual effect of natural organic matter on the two-step internalization process of Au@Sio2 in freshwater.
Dingyuan Liang (2020)
10.1016/J.BIOMATERIALS.2007.07.029
Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential.
Swanand D. Patil (2007)
10.3390/jfb6020171
Carbohydrate-Derived Amphiphilic Macromolecules: A Biophysical Structural Characterization and Analysis of Binding Behaviors to Model Membranes
Adriana A. T. Martin (2015)
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