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Microbial Reduction Of 2-keto Acetals As A Biocatalytic Approach To The Enantioselective Synthesis Of Optically Active 2-hydroxy Acetals

P. Ferraboschi, E. Santaniello, M. Tingoli, F. Aragozzini, F. Molinari
Published 1993 · Chemistry

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Abstract The reduction of the 2-keto acetals 1a and 1b by means of different microorganisms constitutes the biocatalytic access to optically active (46 to 100% ee) 2-hydroxy acetals, (S)-2a or (R)- and (S)-2b, representative compounds of a class of synthetically useful chiral building blocks.
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